Click here to switch to the map view.

The map label for this gene is cocE [H]

Identifier: 182680872

GI number: 182680872

Start: 398178

End: 400169

Strand: Reverse

Name: cocE [H]

Synonym: XfasM23_0309

Alternate gene names: 182680872

Gene position: 400169-398178 (Counterclockwise)

Preceding gene: 182680873

Following gene: 182680870

Centisome position: 15.78

GC content: 52.46

Gene sequence:

>1992_bases
ATGCGCCGCTTCATCGCCGCTCTATCCTTCATCCTGCCTCTTGCCGCAATCGCCCAAACTGCACCCATGACACCTGACAT
CACCGGCAGGCAATTCGTCGTGCCAACAGAAAAGGACGATTACATCAAACGTGAAGTGATGATTCCGATGCGTGACGGAA
CAAAGCTACACACCGTCATTATTATTCCCAAGAAAGCCCAGCATGCACCGATGTTGCTCACACGAACACCATACAACGCC
AACGAGCGTAGCGAACGCATACTATCACCGCACATGAAAAACCTCCTGCCACAGGGAGATGACGTGTTCGCAACCGGCGA
CTACATCCGCGTGTTCCAAGACGTACGCGGCAAGTACGGCTCGGAAGGAGACTACGTTGTGACCCGACCATTACGGGGTG
TGCTCAACCTCACCAATATCGATCATGCAACCGATGCCTGGGACACCATTGATTGGTTGGTGAAAAACATCAAGCAGTCT
AATGGCAACGTCGGCATGATCGGCTCCTCGTATGAAGGGTTCACCGTCGTGATGGCCCTGACCGATCCACACCCAGCGTT
AAAAGTGGCTGCACCGGAAAGCCCGATGATTGATGGTTGGATGGGCGATGACTGGTTCAACTACGGCGCCTTCCGCCAAG
TCAATTTCGACTATTTCTCTGGCCAGATGACCAATCGCGGCAAAGGCCTATCCATCGCACGCCAAGGTTACGACGACTAC
AGCAACTTTCTGCAAGCAGGCTCGGCCGGCAACTATGCTAAAGCCGCAGGTTTAGAACAATTACCCTGGTGGCACAAACT
CACCGAACATCCAGCGTATGACAGCTTCTGGCAAGAACAAGCACTGGATAAAGTCATGGCACGCACCCCACTGAAAGTCC
CCACAATGTGGTTGCAGGGCCTATGGGATCAAGAAGACATGTGGGGAGCAATCCATTGTTATGCCGCGATGGAACCACGC
GACGTACACAACGACAAAAATTACTTGGTGATGGGTCCATGGCGTCACAGCCAAGTCAACTATGACGGCAGCAACCTAGG
CACCCTCAAATTCGACGGCAACACCTCACTGCAATTCCGCCACGATGTACTGAAACCATTCTTCGATCAATACTTGATTG
ATGGTGCCTCCAAAGCAGACACACCGCCTGTCCTTATCTACAACACTGGAGCGAACCATTGGGACCGCATGCAACACTGG
CCACGTAGCTGTGAGCGTGGCTGCGAGTACACATCCAAGCCGCTATACCTCAATGCTGGCGGCACACTGTCATTCCAGAC
ATCGCAAAGAAAGCAAAATGATTACGACGAATACATCTCCGATCCTGCTAACCCAGTCCCCTTTATGCCACGTCCAATAA
ACTTCAAAGACAACGCGATGTGGAGCACCTGGCTGGTTCAGGATCAACGCTTCGTTGACAACCGTCCAGACGTGTTGACT
TACCTCAGTGAACCACTGACCACACCCCTGCAAATCGCAGGCGTACCCCGGATCAACCTGCATGCCTCCACAAGTGGCAC
AGATAGCGATTGGGTGGTCAAACTGATTGATGTCTATCCAGATGAAATAGCATCCGATCCAAAGATGGGGGGCAACGAAC
TGGCAATATCACTCGGCATCTTCCGTGGCCGCTACCGCACCAGCTTCCAATATCCAACCCCAATGACGCCGAATCAGCCG
CTGTTGTACCGTTTCGACCTCCCAAATGCCAACCATACGTTCCTCACTGGACACCGCATCATGGTGCAGGTGCAATCCAG
CCTGTTTCCACTGTACGACCGCAACCCGCAGCGCTACGTACCGAATATCTTTTTCGCCAAACCTGATGATTACATCAAAG
CAACCCAACGCATCTGGCACACACCACGACAACCCAGTTTCGTCGAACTTCCTGTGGTGAATCCAGACATACTCACACAG
TGGACTCATTGGAACATCGGCAGCTCTCACAAAACAACGTTACCTACCCCATCACTCTCTGACTGGTTGTAG

Upstream 100 bases:

>100_bases
ACCTCACGATCCATGAGGTAGCACTGCGATAACACATCCATCGACTCTGTTTCAGCTACGTATTACATTTCATATACCCC
CGACCGGCTCAGAACTATTT

Downstream 100 bases:

>100_bases
AACACACATCATAATTGTGCAGCGTGACTTTGCTCCTGCGATGCCGATACAAATTCCCCACCCATCAACATTTTGATGCT
GACTGGATTCGACGGACATT

Product: X-Pro dipeptidyl-peptidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MRRFIAALSFILPLAAIAQTAPMTPDITGRQFVVPTEKDDYIKREVMIPMRDGTKLHTVIIIPKKAQHAPMLLTRTPYNA
NERSERILSPHMKNLLPQGDDVFATGDYIRVFQDVRGKYGSEGDYVVTRPLRGVLNLTNIDHATDAWDTIDWLVKNIKQS
NGNVGMIGSSYEGFTVVMALTDPHPALKVAAPESPMIDGWMGDDWFNYGAFRQVNFDYFSGQMTNRGKGLSIARQGYDDY
SNFLQAGSAGNYAKAAGLEQLPWWHKLTEHPAYDSFWQEQALDKVMARTPLKVPTMWLQGLWDQEDMWGAIHCYAAMEPR
DVHNDKNYLVMGPWRHSQVNYDGSNLGTLKFDGNTSLQFRHDVLKPFFDQYLIDGASKADTPPVLIYNTGANHWDRMQHW
PRSCERGCEYTSKPLYLNAGGTLSFQTSQRKQNDYDEYISDPANPVPFMPRPINFKDNAMWSTWLVQDQRFVDNRPDVLT
YLSEPLTTPLQIAGVPRINLHASTSGTDSDWVVKLIDVYPDEIASDPKMGGNELAISLGIFRGRYRTSFQYPTPMTPNQP
LLYRFDLPNANHTFLTGHRIMVQVQSSLFPLYDRNPQRYVPNIFFAKPDDYIKATQRIWHTPRQPSFVELPVVNPDILTQ
WTHWNIGSSHKTTLPTPSLSDWL

Sequences:

>Translated_663_residues
MRRFIAALSFILPLAAIAQTAPMTPDITGRQFVVPTEKDDYIKREVMIPMRDGTKLHTVIIIPKKAQHAPMLLTRTPYNA
NERSERILSPHMKNLLPQGDDVFATGDYIRVFQDVRGKYGSEGDYVVTRPLRGVLNLTNIDHATDAWDTIDWLVKNIKQS
NGNVGMIGSSYEGFTVVMALTDPHPALKVAAPESPMIDGWMGDDWFNYGAFRQVNFDYFSGQMTNRGKGLSIARQGYDDY
SNFLQAGSAGNYAKAAGLEQLPWWHKLTEHPAYDSFWQEQALDKVMARTPLKVPTMWLQGLWDQEDMWGAIHCYAAMEPR
DVHNDKNYLVMGPWRHSQVNYDGSNLGTLKFDGNTSLQFRHDVLKPFFDQYLIDGASKADTPPVLIYNTGANHWDRMQHW
PRSCERGCEYTSKPLYLNAGGTLSFQTSQRKQNDYDEYISDPANPVPFMPRPINFKDNAMWSTWLVQDQRFVDNRPDVLT
YLSEPLTTPLQIAGVPRINLHASTSGTDSDWVVKLIDVYPDEIASDPKMGGNELAISLGIFRGRYRTSFQYPTPMTPNQP
LLYRFDLPNANHTFLTGHRIMVQVQSSLFPLYDRNPQRYVPNIFFAKPDDYIKATQRIWHTPRQPSFVELPVVNPDILTQ
WTHWNIGSSHKTTLPTPSLSDWL
>Mature_663_residues
MRRFIAALSFILPLAAIAQTAPMTPDITGRQFVVPTEKDDYIKREVMIPMRDGTKLHTVIIIPKKAQHAPMLLTRTPYNA
NERSERILSPHMKNLLPQGDDVFATGDYIRVFQDVRGKYGSEGDYVVTRPLRGVLNLTNIDHATDAWDTIDWLVKNIKQS
NGNVGMIGSSYEGFTVVMALTDPHPALKVAAPESPMIDGWMGDDWFNYGAFRQVNFDYFSGQMTNRGKGLSIARQGYDDY
SNFLQAGSAGNYAKAAGLEQLPWWHKLTEHPAYDSFWQEQALDKVMARTPLKVPTMWLQGLWDQEDMWGAIHCYAAMEPR
DVHNDKNYLVMGPWRHSQVNYDGSNLGTLKFDGNTSLQFRHDVLKPFFDQYLIDGASKADTPPVLIYNTGANHWDRMQHW
PRSCERGCEYTSKPLYLNAGGTLSFQTSQRKQNDYDEYISDPANPVPFMPRPINFKDNAMWSTWLVQDQRFVDNRPDVLT
YLSEPLTTPLQIAGVPRINLHASTSGTDSDWVVKLIDVYPDEIASDPKMGGNELAISLGIFRGRYRTSFQYPTPMTPNQP
LLYRFDLPNANHTFLTGHRIMVQVQSSLFPLYDRNPQRYVPNIFFAKPDDYIKATQRIWHTPRQPSFVELPVVNPDILTQ
WTHWNIGSSHKTTLPTPSLSDWL

Specific function: Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants [H]

COG id: COG2936

COG function: function code R; Predicted acyl esterases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alpha/beta hydrolase family. Carboxylesterase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005674
- InterPro:   IPR008979
- InterPro:   IPR013736
- InterPro:   IPR000383 [H]

Pfam domain/function: PF02129 Peptidase_S15; PF08530 PepX_C [H]

EC number: NA

Molecular weight: Translated: 75696; Mature: 75696

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFIAALSFILPLAAIAQTAPMTPDITGRQFVVPTEKDDYIKREVMIPMRDGTKLHTVI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCEEEEEE
IIPKKAQHAPMLLTRTPYNANERSERILSPHMKNLLPQGDDVFATGDYIRVFQDVRGKYG
EEECCCCCCCEEEEECCCCCCHHHHHHHCHHHHHHCCCCCCEEECCHHHHHHHHHHHCCC
SEGDYVVTRPLRGVLNLTNIDHATDAWDTIDWLVKNIKQSNGNVGMIGSSYEGFTVVMAL
CCCCEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEE
TDPHPALKVAAPESPMIDGWMGDDWFNYGAFRQVNFDYFSGQMTNRGKGLSIARQGYDDY
ECCCCCEEEECCCCCCCCCCCCCCHHCCCCEEEECCHHCCCEECCCCCCCCHHHCCCHHH
SNFLQAGSAGNYAKAAGLEQLPWWHKLTEHPAYDSFWQEQALDKVMARTPLKVPTMWLQG
HHHHHCCCCCCCHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHC
LWDQEDMWGAIHCYAAMEPRDVHNDKNYLVMGPWRHSQVNYDGSNLGTLKFDGNTSLQFR
CCCCCCCCEEEEEEEECCCHHCCCCCCEEEECCCCCCEECCCCCCEEEEEECCCCCEEHH
HDVLKPFFDQYLIDGASKADTPPVLIYNTGANHWDRMQHWPRSCERGCEYTSKPLYLNAG
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECC
GTLSFQTSQRKQNDYDEYISDPANPVPFMPRPINFKDNAMWSTWLVQDQRFVDNRPDVLT
CEEEEECCHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHCCCCCHHHH
YLSEPLTTPLQIAGVPRINLHASTSGTDSDWVVKLIDVYPDEIASDPKMGGNELAISLGI
HHHCCCCCCEEECCCCEEEEEECCCCCCCHHEEEEEHHCCHHHCCCCCCCCCEEEEEEEE
FRGRYRTSFQYPTPMTPNQPLLYRFDLPNANHTFLTGHRIMVQVQSSLFPLYDRNPQRYV
ECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCEEEEEEECCCCCCCCCCCHHHC
PNIFFAKPDDYIKATQRIWHTPRQPSFVELPVVNPDILTQWTHWNIGSSHKTTLPTPSLS
CEEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHEEEEECCCCCCCCCCCCCCCHH
DWL
CCC
>Mature Secondary Structure
MRRFIAALSFILPLAAIAQTAPMTPDITGRQFVVPTEKDDYIKREVMIPMRDGTKLHTVI
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEEEEEECCCCEEEEEE
IIPKKAQHAPMLLTRTPYNANERSERILSPHMKNLLPQGDDVFATGDYIRVFQDVRGKYG
EEECCCCCCCEEEEECCCCCCHHHHHHHCHHHHHHCCCCCCEEECCHHHHHHHHHHHCCC
SEGDYVVTRPLRGVLNLTNIDHATDAWDTIDWLVKNIKQSNGNVGMIGSSYEGFTVVMAL
CCCCEEEECCCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEE
TDPHPALKVAAPESPMIDGWMGDDWFNYGAFRQVNFDYFSGQMTNRGKGLSIARQGYDDY
ECCCCCEEEECCCCCCCCCCCCCCHHCCCCEEEECCHHCCCEECCCCCCCCHHHCCCHHH
SNFLQAGSAGNYAKAAGLEQLPWWHKLTEHPAYDSFWQEQALDKVMARTPLKVPTMWLQG
HHHHHCCCCCCCHHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHC
LWDQEDMWGAIHCYAAMEPRDVHNDKNYLVMGPWRHSQVNYDGSNLGTLKFDGNTSLQFR
CCCCCCCCEEEEEEEECCCHHCCCCCCEEEECCCCCCEECCCCCCEEEEEECCCCCEEHH
HDVLKPFFDQYLIDGASKADTPPVLIYNTGANHWDRMQHWPRSCERGCEYTSKPLYLNAG
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECC
GTLSFQTSQRKQNDYDEYISDPANPVPFMPRPINFKDNAMWSTWLVQDQRFVDNRPDVLT
CEEEEECCHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECHHHCCCCCHHHH
YLSEPLTTPLQIAGVPRINLHASTSGTDSDWVVKLIDVYPDEIASDPKMGGNELAISLGI
HHHCCCCCCEEECCCCEEEEEECCCCCCCHHEEEEEHHCCHHHCCCCCCCCCEEEEEEEE
FRGRYRTSFQYPTPMTPNQPLLYRFDLPNANHTFLTGHRIMVQVQSSLFPLYDRNPQRYV
ECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEECCEEEEEEECCCCCCCCCCCHHHC
PNIFFAKPDDYIKATQRIWHTPRQPSFVELPVVNPDILTQWTHWNIGSSHKTTLPTPSLS
CEEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHEEEEECCCCCCCCCCCCCCCHH
DWL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10698749; 11742345; 12369817 [H]