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The map label for this gene is luxQ [H]

Identifier: 182680827

GI number: 182680827

Start: 341095

End: 342732

Strand: Reverse

Name: luxQ [H]

Synonym: XfasM23_0262

Alternate gene names: 182680827

Gene position: 342732-341095 (Counterclockwise)

Preceding gene: 182680828

Following gene: 182680821

Centisome position: 13.52

GC content: 55.07

Gene sequence:

>1638_bases
ATGCCACTGAAACAACAGAGCCAAACACCACCTACCGTACAAAGCGCGATCCTACAAACCACCCAAGACAGCAATACCAC
CCTTCATTGCAGTCTGGAACACTTACCGCAAGGGGTGGTGATTATCGACGCCGAACTGCGTCTAGCTGCTTGGAATACAC
GTTACGTCGAACTCTTCCACTTCCCCCCGGAACTGATGCAAGTCGGCCAACCGATCGAAGATTTATTCCGTTACAACGCA
GAGCGTGGCCTCCTTGGTGATGGCCCCATTGAAGAGGCAATCCAACGCCGCCTCAACCACCTGCGCAGCGGCAAGGCACA
CATCCGTGAAAGCGAGAAAGAAGACGGCACAGTACTGGAAATTCGCGGAAATTCCCTGCCAGAGGGTGGCTTCGTCACCA
GCTACACCGACATCACCAGCTACAAAAACGCCACACGCGAACTACGTTTACTCGCCGACACACTCGAACACCGTGTCGCC
GAGCGCACTCGCGACCTGGACCAAGCACGCCTTGAAGCCGAGAATGCCAATCGTTATAAAACCCGTTTCATCGCCTCAGC
AGTACACGATCTACTGCAACCACTCAATGCAGCACGCATGTTTGTAGCAATGTTGCGCAAACAATTGCACGACACAGATG
CACTGCGCATCGCCAACAACATTGATGGGGCGCTGATCGCAGAAGATGCCATCCTCAGCAGTCTACTGGACATCTCGCGG
CTTGAATCAGGTACCTTAAAAACGCAAGTGCATCACTTTGCACTGGGAACACTGCTAGAAACGCTGGCAGGTGAATTTGG
CATCCTTGCGCAAAGTCGCGGAATCTCCCTCAAATGGGTACCAAGCCATGCCATCGTATACAGCGACGAAACATTACTTC
GGCGGATTTTGCAGAATTTCCTTTCTAACGCAATCCGCTACACCCCGCGCGGACGCGTGCTGATAGGCTGCCGGCGACAT
GGCAACTGGTTACGCATCGAAGTACATGACCAAGGACCGGGCATTCCCGAAAGCTTGCAAAGCGAAATCTTCGAGGAATT
TCGACGCCTTGATGACGGCGTAGTCAACGACCGCGGTGCCGGCCTTGGATTGGCCATCGTCGAACGCATCGGACGCCTGC
TCAACCACCCTATCGGACTACGCTCCACACTTGGACATGGCAGCACGTTTTCAGTCAGCGTACCACTGGAGCAGATCACA
ACAACCCACCCCGTATTCACACGGACACCAATGCCCACCCGCGAGCTGGATGATGACCCGATGCTGCATGGCTGCCAGGT
CTGGTGTATAGACAACGACCCGAGCGTCTGCCAAATCATCCACACCCTGCTGGAACGCTGGCACTGTGCGGTTGGCTTTA
CCGGGAGTCTGGACGAAGCACTCATCACCGCCGCCACTGCACCACCGCCCGAACTGATCCTGATGGACACCAGTATCGAT
GAACACGGCGACACCCCTCTAATACCATTGCTGATGACACACTGGGGACACACACCACGCGTGATCCTGATGACCTCCGA
AGAAGATCCAACCCTACGCGACCGGGCATTGAATCGAGGCTGGGGCTTCCTGGGAAAACCTATACGGCCACCGGCATTAC
GTGCACTGATGACACAAACACTGCTACGCCAAGACTGA

Upstream 100 bases:

>100_bases
AGCACCAACCACATTTGGCTGACACAGAGGACGAGCAATGTTCATTCAGCAGCAACATTGCCTGGCCATGCTGTGCTAGA
GCAACAGACATAAACAAAAC

Downstream 100 bases:

>100_bases
ACACAACACAGAACATCCTTCACCAGCCGCGTTTATAAAGCCGTGTCTAGGCTTCAGGCTCAAGCGACTTCACCAATACC
GCTGCCTGGGTACGGCTATA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MPLKQQSQTPPTVQSAILQTTQDSNTTLHCSLEHLPQGVVIIDAELRLAAWNTRYVELFHFPPELMQVGQPIEDLFRYNA
ERGLLGDGPIEEAIQRRLNHLRSGKAHIRESEKEDGTVLEIRGNSLPEGGFVTSYTDITSYKNATRELRLLADTLEHRVA
ERTRDLDQARLEAENANRYKTRFIASAVHDLLQPLNAARMFVAMLRKQLHDTDALRIANNIDGALIAEDAILSSLLDISR
LESGTLKTQVHHFALGTLLETLAGEFGILAQSRGISLKWVPSHAIVYSDETLLRRILQNFLSNAIRYTPRGRVLIGCRRH
GNWLRIEVHDQGPGIPESLQSEIFEEFRRLDDGVVNDRGAGLGLAIVERIGRLLNHPIGLRSTLGHGSTFSVSVPLEQIT
TTHPVFTRTPMPTRELDDDPMLHGCQVWCIDNDPSVCQIIHTLLERWHCAVGFTGSLDEALITAATAPPPELILMDTSID
EHGDTPLIPLLMTHWGHTPRVILMTSEEDPTLRDRALNRGWGFLGKPIRPPALRALMTQTLLRQD

Sequences:

>Translated_545_residues
MPLKQQSQTPPTVQSAILQTTQDSNTTLHCSLEHLPQGVVIIDAELRLAAWNTRYVELFHFPPELMQVGQPIEDLFRYNA
ERGLLGDGPIEEAIQRRLNHLRSGKAHIRESEKEDGTVLEIRGNSLPEGGFVTSYTDITSYKNATRELRLLADTLEHRVA
ERTRDLDQARLEAENANRYKTRFIASAVHDLLQPLNAARMFVAMLRKQLHDTDALRIANNIDGALIAEDAILSSLLDISR
LESGTLKTQVHHFALGTLLETLAGEFGILAQSRGISLKWVPSHAIVYSDETLLRRILQNFLSNAIRYTPRGRVLIGCRRH
GNWLRIEVHDQGPGIPESLQSEIFEEFRRLDDGVVNDRGAGLGLAIVERIGRLLNHPIGLRSTLGHGSTFSVSVPLEQIT
TTHPVFTRTPMPTRELDDDPMLHGCQVWCIDNDPSVCQIIHTLLERWHCAVGFTGSLDEALITAATAPPPELILMDTSID
EHGDTPLIPLLMTHWGHTPRVILMTSEEDPTLRDRALNRGWGFLGKPIRPPALRALMTQTLLRQD
>Mature_544_residues
PLKQQSQTPPTVQSAILQTTQDSNTTLHCSLEHLPQGVVIIDAELRLAAWNTRYVELFHFPPELMQVGQPIEDLFRYNAE
RGLLGDGPIEEAIQRRLNHLRSGKAHIRESEKEDGTVLEIRGNSLPEGGFVTSYTDITSYKNATRELRLLADTLEHRVAE
RTRDLDQARLEAENANRYKTRFIASAVHDLLQPLNAARMFVAMLRKQLHDTDALRIANNIDGALIAEDAILSSLLDISRL
ESGTLKTQVHHFALGTLLETLAGEFGILAQSRGISLKWVPSHAIVYSDETLLRRILQNFLSNAIRYTPRGRVLIGCRRHG
NWLRIEVHDQGPGIPESLQSEIFEEFRRLDDGVVNDRGAGLGLAIVERIGRLLNHPIGLRSTLGHGSTFSVSVPLEQITT
THPVFTRTPMPTRELDDDPMLHGCQVWCIDNDPSVCQIIHTLLERWHCAVGFTGSLDEALITAATAPPPELILMDTSIDE
HGDTPLIPLLMTHWGHTPRVILMTSEEDPTLRDRALNRGWGFLGKPIRPPALRALMTQTLLRQD

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=315, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI48994928, Length=409, Percent_Identity=25.4278728606357, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=26.0869565217391, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789149, Length=272, Percent_Identity=30.5147058823529, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=412, Percent_Identity=26.6990291262136, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=240, Percent_Identity=27.9166666666667, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=237, Percent_Identity=29.957805907173, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1786783, Length=168, Percent_Identity=29.7619047619048, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=27.027027027027, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1786600, Length=278, Percent_Identity=25.5395683453237, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=27.6679841897233, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=28.8793103448276, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61053; Mature: 60921

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKQQSQTPPTVQSAILQTTQDSNTTLHCSLEHLPQGVVIIDAELRLAAWNTRYVELFH
CCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCCEEEEECCEEEEECCCEEEEEEE
FPPELMQVGQPIEDLFRYNAERGLLGDGPIEEAIQRRLNHLRSGKAHIRESEKEDGTVLE
CCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEE
IRGNSLPEGGFVTSYTDITSYKNATRELRLLADTLEHRVAERTRDLDQARLEAENANRYK
ECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TRFIASAVHDLLQPLNAARMFVAMLRKQLHDTDALRIANNIDGALIAEDAILSSLLDISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LESGTLKTQVHHFALGTLLETLAGEFGILAQSRGISLKWVPSHAIVYSDETLLRRILQNF
HCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEECCHHHHHHHHHHH
LSNAIRYTPRGRVLIGCRRHGNWLRIEVHDQGPGIPESLQSEIFEEFRRLDDGVVNDRGA
HHHHHEECCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GLGLAIVERIGRLLNHPIGLRSTLGHGSTFSVSVPLEQITTTHPVFTRTPMPTRELDDDP
CHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCHHHHCCCCCCEECCCCCCCCCCCCC
MLHGCQVWCIDNDPSVCQIIHTLLERWHCAVGFTGSLDEALITAATAPPPELILMDTSID
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCCC
EHGDTPLIPLLMTHWGHTPRVILMTSEEDPTLRDRALNRGWGFLGKPIRPPALRALMTQT
CCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LLRQD
HHHCC
>Mature Secondary Structure 
PLKQQSQTPPTVQSAILQTTQDSNTTLHCSLEHLPQGVVIIDAELRLAAWNTRYVELFH
CCCCCCCCCCHHHHHHHHHCCCCCCEEEEEHHHCCCCEEEEECCEEEEECCCEEEEEEE
FPPELMQVGQPIEDLFRYNAERGLLGDGPIEEAIQRRLNHLRSGKAHIRESEKEDGTVLE
CCHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEE
IRGNSLPEGGFVTSYTDITSYKNATRELRLLADTLEHRVAERTRDLDQARLEAENANRYK
ECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
TRFIASAVHDLLQPLNAARMFVAMLRKQLHDTDALRIANNIDGALIAEDAILSSLLDISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LESGTLKTQVHHFALGTLLETLAGEFGILAQSRGISLKWVPSHAIVYSDETLLRRILQNF
HCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCEEEECCHHHHHHHHHHH
LSNAIRYTPRGRVLIGCRRHGNWLRIEVHDQGPGIPESLQSEIFEEFRRLDDGVVNDRGA
HHHHHEECCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
GLGLAIVERIGRLLNHPIGLRSTLGHGSTFSVSVPLEQITTTHPVFTRTPMPTRELDDDP
CHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCHHHHCCCCCCEECCCCCCCCCCCCC
MLHGCQVWCIDNDPSVCQIIHTLLERWHCAVGFTGSLDEALITAATAPPPELILMDTSID
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCEEEEECCCC
EHGDTPLIPLLMTHWGHTPRVILMTSEEDPTLRDRALNRGWGFLGKPIRPPALRALMTQT
CCCCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
LLRQD
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA