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The map label for this gene is degQ [H]

Identifier: 182680791

GI number: 182680791

Start: 293772

End: 295217

Strand: Reverse

Name: degQ [H]

Synonym: XfasM23_0220

Alternate gene names: 182680791

Gene position: 295217-293772 (Counterclockwise)

Preceding gene: 182680792

Following gene: 182680790

Centisome position: 11.64

GC content: 55.26

Gene sequence:

>1446_bases
ATGCGACCGCTACCTACTTTACTGACGCTATCTATCGCTGCCGCATTCGGCGGTTTTGCAGCCACTGGGATGAATGCTTG
GCTTGATAACCGCGCCGAAGCGGCATCCAACACCAATGCCATCTCACCAATATCATCACTGCCAACGGGCACGGTGCCTC
AAACCACGGCTACCAACCAGCCGCTACCATCGTTAGCACCCATGCTGCAACAAGTGATGCCAGCAGTGGTCAGCATCAAC
AGTAAACAAGTGGTACGGGTGCGCAATCCATTTTTCGACGACCCGATCCTACGTCGGCTATTCCCAGAGATCCCCCAAGA
ACGGATTAATGAGTCGCTCGGATCTGGGGTGATCATCGACGCGCGCAATGGCTACGTACTTACCAATCATCACGTGATCG
AAAATGCCGACGCCGTGCAGGTGACATTAGCAGATGGGCGCAGCTTCAAGGCCGAGTTCCTCGGTTCTGACGCAGACACC
GACATCGCCTTGATCCGGATCAAAGCAAATAAACTGACCGAAATCAAACTCGCAGACAGTAACAAATTACGCGTGGGCGA
CTTCGTCGTAGCCATTGGTAACCCGTTCGGCTTTACCCAAACGGTGACCTCAGGCATCGTCTCGGCGGTAGGTCGCAGTG
GCATCCTCGGCCTGGGTTACCAAAACTTCATCCAAACCGACGCATCGATCAACCCGGGTAACTCAGGCGGCGCACTGGTG
AATCTTCATGGCCAGTTGGTTGGCATCAACACGGCCAGCTTCAACCCACAGGGCAGCATGGCTGGCAACATCGGCTTAGG
CCTGGCAATTCCTTCGAATCTAGCGCGCAACGTCGTCGAGCAATTGGTCACGAAAGGCGTTGTGGTACGCGGGACAATCG
GCGTACAAACACAGAATATTGATGCACGAATGGCACAAAGCTTAGGCCTGAGTAATCCACACGGCGCATTAGTGACTCGC
GTATTACCCAATTCCGCTGGTGCCGCAGCCGGACTGCAACCAGGTGATGTGATCCTGGCAGCCAATGACCAAAGGGTGGA
CAACGCGGAAACATTGCACAACTACGAAGGACTACAGCCCGTCGGTAGCTCAGTAACACTGGAAGTACACCGTGGCGGCA
AGCCACTCAAAATACGCCTCACACTCAAAGAATTGCCACGCGCAATCGCCGGAGAAACGCTGGATTCACGACTGTCGGGC
GCCATCTTCGTTGACCTGCCAGAGTCCCTCCGTCAATCAGGAATCGGTGGAGTCATGGTCAACAAAATCAAACACGGCAG
CCGCGCTGCGGCCAATGGGTTGGTAGCCGGAGATGTCATCATTGCCGCATCCATCGGTGAATTCTCTGATCTGGCGAGCT
GGCGGGCAAGCTTTTCCCACCCACCACAACGGCTGATACTGCGTGTGCTGCGCGGTAACGCACAGTATGATGCGCTGATG
CGCTGA

Upstream 100 bases:

>100_bases
ATCATAAGTTAAATGGAGTGGACGCACTCTATTATGGGTTGGTTTATCCAGCAGCCGACCCTATTCCATCTGTGCTCTGA
CCACATTTGAAAATCTCAAA

Downstream 100 bases:

>100_bases
TGCGCTGTCGTTAGGCATCATCGTCGGCACCTTGATCGGCAGATTCACCGATATAGTCGACTGACCACAAACGTTCCTCA
CCCACCCAGAATTCTCGTAT

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRPLPTLLTLSIAAAFGGFAATGMNAWLDNRAEAASNTNAISPISSLPTGTVPQTTATNQPLPSLAPMLQQVMPAVVSIN
SKQVVRVRNPFFDDPILRRLFPEIPQERINESLGSGVIIDARNGYVLTNHHVIENADAVQVTLADGRSFKAEFLGSDADT
DIALIRIKANKLTEIKLADSNKLRVGDFVVAIGNPFGFTQTVTSGIVSAVGRSGILGLGYQNFIQTDASINPGNSGGALV
NLHGQLVGINTASFNPQGSMAGNIGLGLAIPSNLARNVVEQLVTKGVVVRGTIGVQTQNIDARMAQSLGLSNPHGALVTR
VLPNSAGAAAGLQPGDVILAANDQRVDNAETLHNYEGLQPVGSSVTLEVHRGGKPLKIRLTLKELPRAIAGETLDSRLSG
AIFVDLPESLRQSGIGGVMVNKIKHGSRAAANGLVAGDVIIAASIGEFSDLASWRASFSHPPQRLILRVLRGNAQYDALM
R

Sequences:

>Translated_481_residues
MRPLPTLLTLSIAAAFGGFAATGMNAWLDNRAEAASNTNAISPISSLPTGTVPQTTATNQPLPSLAPMLQQVMPAVVSIN
SKQVVRVRNPFFDDPILRRLFPEIPQERINESLGSGVIIDARNGYVLTNHHVIENADAVQVTLADGRSFKAEFLGSDADT
DIALIRIKANKLTEIKLADSNKLRVGDFVVAIGNPFGFTQTVTSGIVSAVGRSGILGLGYQNFIQTDASINPGNSGGALV
NLHGQLVGINTASFNPQGSMAGNIGLGLAIPSNLARNVVEQLVTKGVVVRGTIGVQTQNIDARMAQSLGLSNPHGALVTR
VLPNSAGAAAGLQPGDVILAANDQRVDNAETLHNYEGLQPVGSSVTLEVHRGGKPLKIRLTLKELPRAIAGETLDSRLSG
AIFVDLPESLRQSGIGGVMVNKIKHGSRAAANGLVAGDVIIAASIGEFSDLASWRASFSHPPQRLILRVLRGNAQYDALM
R
>Mature_481_residues
MRPLPTLLTLSIAAAFGGFAATGMNAWLDNRAEAASNTNAISPISSLPTGTVPQTTATNQPLPSLAPMLQQVMPAVVSIN
SKQVVRVRNPFFDDPILRRLFPEIPQERINESLGSGVIIDARNGYVLTNHHVIENADAVQVTLADGRSFKAEFLGSDADT
DIALIRIKANKLTEIKLADSNKLRVGDFVVAIGNPFGFTQTVTSGIVSAVGRSGILGLGYQNFIQTDASINPGNSGGALV
NLHGQLVGINTASFNPQGSMAGNIGLGLAIPSNLARNVVEQLVTKGVVVRGTIGVQTQNIDARMAQSLGLSNPHGALVTR
VLPNSAGAAAGLQPGDVILAANDQRVDNAETLHNYEGLQPVGSSVTLEVHRGGKPLKIRLTLKELPRAIAGETLDSRLSG
AIFVDLPESLRQSGIGGVMVNKIKHGSRAAANGLVAGDVIIAASIGEFSDLASWRASFSHPPQRLILRVLRGNAQYDALM
R

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=341, Percent_Identity=32.5513196480938, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI7019477, Length=333, Percent_Identity=35.1351351351351, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI22129776, Length=357, Percent_Identity=32.7731092436975, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI24308541, Length=244, Percent_Identity=34.0163934426229, Blast_Score=125, Evalue=9e-29,
Organism=Escherichia coli, GI1786356, Length=466, Percent_Identity=43.3476394849785, Blast_Score=332, Evalue=5e-92,
Organism=Escherichia coli, GI1789629, Length=440, Percent_Identity=43.1818181818182, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1789630, Length=278, Percent_Identity=43.5251798561151, Blast_Score=204, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24646839, Length=304, Percent_Identity=33.8815789473684, Blast_Score=149, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 50511; Mature: 50511

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPLPTLLTLSIAAAFGGFAATGMNAWLDNRAEAASNTNAISPISSLPTGTVPQTTATNQ
CCCCHHHHHHHHHHHHCCHHHHCHHHHHCCHHHHCCCCCCCCCHHHCCCCCCCCCCCCCC
PLPSLAPMLQQVMPAVVSINSKQVVRVRNPFFDDPILRRLFPEIPQERINESLGSGVIID
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEE
ARNGYVLTNHHVIENADAVQVTLADGRSFKAEFLGSDADTDIALIRIKANKLTEIKLADS
CCCCEEEECCEEECCCCEEEEEECCCCCEEHHHCCCCCCCCEEEEEEECCCEEEEEECCC
NKLRVGDFVVAIGNPFGFTQTVTSGIVSAVGRSGILGLGYQNFIQTDASINPGNSGGALV
CCEEECEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCCCCCCCCEEE
NLHGQLVGINTASFNPQGSMAGNIGLGLAIPSNLARNVVEQLVTKGVVVRGTIGVQTQNI
EECCEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEEECEEECCC
DARMAQSLGLSNPHGALVTRVLPNSAGAAAGLQPGDVILAANDQRVDNAETLHNYEGLQP
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCC
VGSSVTLEVHRGGKPLKIRLTLKELPRAIAGETLDSRLSGAIFVDLPESLRQSGIGGVMV
CCCEEEEEEECCCCCEEEEEEHHHCCHHHHCCCHHHHCCCEEEEECCHHHHHCCCCCEEE
NKIKHGSRAAANGLVAGDVIIAASIGEFSDLASWRASFSHPPQRLILRVLRGNAQYDALM
HHHCCCCCHHHCCCEECCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHC
R
C
>Mature Secondary Structure
MRPLPTLLTLSIAAAFGGFAATGMNAWLDNRAEAASNTNAISPISSLPTGTVPQTTATNQ
CCCCHHHHHHHHHHHHCCHHHHCHHHHHCCHHHHCCCCCCCCCHHHCCCCCCCCCCCCCC
PLPSLAPMLQQVMPAVVSINSKQVVRVRNPFFDDPILRRLFPEIPQERINESLGSGVIID
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEE
ARNGYVLTNHHVIENADAVQVTLADGRSFKAEFLGSDADTDIALIRIKANKLTEIKLADS
CCCCEEEECCEEECCCCEEEEEECCCCCEEHHHCCCCCCCCEEEEEEECCCEEEEEECCC
NKLRVGDFVVAIGNPFGFTQTVTSGIVSAVGRSGILGLGYQNFIQTDASINPGNSGGALV
CCEEECEEEEEECCCCCHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCCCCCCCCEEE
NLHGQLVGINTASFNPQGSMAGNIGLGLAIPSNLARNVVEQLVTKGVVVRGTIGVQTQNI
EECCEEEEEEECCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCEEEEEEECEEECCC
DARMAQSLGLSNPHGALVTRVLPNSAGAAAGLQPGDVILAANDQRVDNAETLHNYEGLQP
HHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCC
VGSSVTLEVHRGGKPLKIRLTLKELPRAIAGETLDSRLSGAIFVDLPESLRQSGIGGVMV
CCCEEEEEEECCCCCEEEEEEHHHCCHHHHCCCHHHHCCCEEEEECCHHHHHCCCCCEEE
NKIKHGSRAAANGLVAGDVIIAASIGEFSDLASWRASFSHPPQRLILRVLRGNAQYDALM
HHHCCCCCHHHCCCEECCEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]