BacMap

Definition	Xylella fastidiosa M23 chromosome, complete genome.
Accession	NC_010577
Length	2,535,690

Click here to switch to the map view.

The map label for this gene is sdh [H]

Identifier: 182680678

GI number: 182680678

Start: 145902

End: 146717

Strand: Reverse

Name: sdh [H]

Synonym: XfasM23_0107

Alternate gene names: 182680678

Gene position: 146717-145902 (Counterclockwise)

Preceding gene: 182680679

Following gene: 182680676

Centisome position: 5.79

GC content: 57.11

Gene sequence:

>816_bases
ATGACTAAAACCATATTGATCACAGGAGCCACATCCGGCTTCGGCAGAGCCGCCGTGCATCGCTTCGCCAACGCCGGCTG
GCGTGTCATCGCCACAGGACGCCGCATTGAGCGCCTGGAAGCACTCGCCGCCGAATGGCCTCCTGGACACATCCACATCA
CCGCCTTCGATATGCGGGATAGCGCCACACTACACACCGCGATTCAAACGCTACCAGCAGACTTTGCCGACATCGACGTC
CTGGTCAACAACGCTGGTCTGGCACTGGGCACCGCACCAGCACAACACGCCGACCTGGCACAGTGGCGGGAGATGATCGA
CACCAACATCACCTCATTGGTGACCTTAACCCACCACGTCCTACCGACACTGATCGAACGCAAAGGCACGATCATCAACA
TCAGCTCCGTCGCCGCGACCTATCCCTACACAGGCGGTAATGTTTACGCTGGCACGAAAGCATTTGTGAAACAATTTTCC
CTGGGCCTGCGCTCGGATCTCCATGGCACCGGCGTACGCGTGACCAGCATAGAACCAGGGATGGCCGAGACCGAATTCAC
CTTAGTCCGTACTGGCGGCAACCAAGCCGCTTCCGACGCTCTGTATCGTGGCGCTCACCCGATCACAGCCGAAGATATTG
CCGAACAAATCTTCTACGTCGCCACACTACCACCACATCTCAACATCAATCGGCTAGAGATCATGCCCGTTAACCAATCG
TTCGCTGGCTTCCAAGTCGCACGACAACAGCAATCACAATTGATCACCCCGCCCCACACACTTCCCACTCACTCCAGCGG
CACATCTGACAAATAG

Upstream 100 bases:

>100_bases
AACACCGTGGCCACATGCAGCAATCGTTTTCACTCCCACCAACCATGCACAGCGTCGTCGATACAACCATCTACCACTAT
CCGCCACATACAGACACGCC

Downstream 100 bases:

>100_bases
GGATAACCCGTCAGACCGGCTTCCAACATATCGCTCAATGCCTTGGACTCCGCAGCAGACATCCCCGCCGCCGCAATACG
TTGCGCATAAACCCTGCGCA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTKTILITGATSGFGRAAVHRFANAGWRVIATGRRIERLEALAAEWPPGHIHITAFDMRDSATLHTAIQTLPADFADIDV
LVNNAGLALGTAPAQHADLAQWREMIDTNITSLVTLTHHVLPTLIERKGTIINISSVAATYPYTGGNVYAGTKAFVKQFS
LGLRSDLHGTGVRVTSIEPGMAETEFTLVRTGGNQAASDALYRGAHPITAEDIAEQIFYVATLPPHLNINRLEIMPVNQS
FAGFQVARQQQSQLITPPHTLPTHSSGTSDK

Sequences:

>Translated_271_residues
MTKTILITGATSGFGRAAVHRFANAGWRVIATGRRIERLEALAAEWPPGHIHITAFDMRDSATLHTAIQTLPADFADIDV
LVNNAGLALGTAPAQHADLAQWREMIDTNITSLVTLTHHVLPTLIERKGTIINISSVAATYPYTGGNVYAGTKAFVKQFS
LGLRSDLHGTGVRVTSIEPGMAETEFTLVRTGGNQAASDALYRGAHPITAEDIAEQIFYVATLPPHLNINRLEIMPVNQS
FAGFQVARQQQSQLITPPHTLPTHSSGTSDK
>Mature_270_residues
TKTILITGATSGFGRAAVHRFANAGWRVIATGRRIERLEALAAEWPPGHIHITAFDMRDSATLHTAIQTLPADFADIDVL
VNNAGLALGTAPAQHADLAQWREMIDTNITSLVTLTHHVLPTLIERKGTIINISSVAATYPYTGGNVYAGTKAFVKQFSL
GLRSDLHGTGVRVTSIEPGMAETEFTLVRTGGNQAASDALYRGAHPITAEDIAEQIFYVATLPPHLNINRLEIMPVNQSF
AGFQVARQQQSQLITPPHTLPTHSSGTSDK

Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me

COG id: COG4221

COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI109715829, Length=245, Percent_Identity=28.1632653061224, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI40548397, Length=186, Percent_Identity=32.7956989247312, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI214010158, Length=186, Percent_Identity=32.7956989247312, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI214010156, Length=186, Percent_Identity=32.7956989247312, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI22758144, Length=186, Percent_Identity=32.7956989247312, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=30.9278350515464, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=30.5699481865285, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI150247226, Length=187, Percent_Identity=30.4812834224599, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI22507405, Length=184, Percent_Identity=29.3478260869565, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7706318, Length=186, Percent_Identity=29.0322580645161, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI7657478, Length=191, Percent_Identity=31.9371727748691, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI4557649, Length=199, Percent_Identity=29.1457286432161, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157739938, Length=229, Percent_Identity=24.8908296943231, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226371731, Length=189, Percent_Identity=28.042328042328, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI50726952, Length=188, Percent_Identity=30.3191489361702, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI119392083, Length=189, Percent_Identity=27.5132275132275, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI31542939, Length=240, Percent_Identity=25.8333333333333, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI19743808, Length=187, Percent_Identity=26.2032085561497, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI44680136, Length=228, Percent_Identity=22.8070175438596, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI44680133, Length=228, Percent_Identity=22.8070175438596, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI17738292, Length=228, Percent_Identity=22.8070175438596, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=51.8218623481781, Blast_Score=257, Evalue=6e-70,
Organism=Escherichia coli, GI1787335, Length=221, Percent_Identity=28.0542986425339, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=35.8288770053476, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=29.2553191489362, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082160, Length=196, Percent_Identity=29.5918367346939, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786812, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=28.3582089552239, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=213, Percent_Identity=36.150234741784, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17560150, Length=213, Percent_Identity=35.6807511737089, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71994604, Length=230, Percent_Identity=29.5652173913043, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17563726, Length=242, Percent_Identity=33.0578512396694, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17560332, Length=244, Percent_Identity=30.327868852459, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=193, Percent_Identity=34.7150259067358, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=231, Percent_Identity=29.4372294372294, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=193, Percent_Identity=32.6424870466321, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=244, Percent_Identity=31.9672131147541, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=200, Percent_Identity=34, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17565030, Length=214, Percent_Identity=32.7102803738318, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562906, Length=198, Percent_Identity=31.8181818181818, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI72000259, Length=198, Percent_Identity=33.8383838383838, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=210, Percent_Identity=30.952380952381, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560220, Length=196, Percent_Identity=35.2040816326531, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=195, Percent_Identity=34.8717948717949, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=209, Percent_Identity=29.1866028708134, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=204, Percent_Identity=28.921568627451, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=243, Percent_Identity=26.7489711934156, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=217, Percent_Identity=30.4147465437788, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=191, Percent_Identity=28.2722513089005, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=190, Percent_Identity=26.8421052631579, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115534694, Length=186, Percent_Identity=30.6451612903226, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=197, Percent_Identity=27.9187817258883, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17558990, Length=221, Percent_Identity=28.5067873303167, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=246, Percent_Identity=35.7723577235772, Blast_Score=167, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6322227, Length=195, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=28.9772727272727, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322226, Length=190, Percent_Identity=23.6842105263158, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=30.6772908366534, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI23397609, Length=231, Percent_Identity=30.7359307359307, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=36.2244897959184, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=29.0196078431373, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=188, Percent_Identity=34.5744680851064, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24644339, Length=187, Percent_Identity=32.0855614973262, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24640442, Length=210, Percent_Identity=29.0476190476191, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24643142, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641388, Length=258, Percent_Identity=28.2945736434109, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358495, Length=227, Percent_Identity=26.8722466960352, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI116007234, Length=253, Percent_Identity=28.0632411067194, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571387, Length=254, Percent_Identity=25.9842519685039, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648693, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21355889, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007238, Length=185, Percent_Identity=29.7297297297297, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648944, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281364494, Length=259, Percent_Identity=23.1660231660232, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24663911, Length=254, Percent_Identity=24.8031496062992, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24580925, Length=247, Percent_Identity=25.5060728744939, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24584744, Length=187, Percent_Identity=28.8770053475936, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=195, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24584748, Length=195, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.276 [H]

Molecular weight: Translated: 29207; Mature: 29076

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTILITGATSGFGRAAVHRFANAGWRVIATGRRIERLEALAAEWPPGHIHITAFDMRD
CCEEEEEEECCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCC
SATLHTAIQTLPADFADIDVLVNNAGLALGTAPAQHADLAQWREMIDTNITSLVTLTHHV
CHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LPTLIERKGTIINISSVAATYPYTGGNVYAGTKAFVKQFSLGLRSDLHGTGVRVTSIEPG
HHHHHHCCCCEEEEHHHEEECCCCCCCEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCC
MAETEFTLVRTGGNQAASDALYRGAHPITAEDIAEQIFYVATLPPHLNINRLEIMPVNQS
CCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHEEEEEECCCCCCCCEEEEEECCCC
FAGFQVARQQQSQLITPPHTLPTHSSGTSDK
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TKTILITGATSGFGRAAVHRFANAGWRVIATGRRIERLEALAAEWPPGHIHITAFDMRD
CEEEEEEECCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHCCCCCEEEEEEEECCC
SATLHTAIQTLPADFADIDVLVNNAGLALGTAPAQHADLAQWREMIDTNITSLVTLTHHV
CHHHHHHHHHCCCCCCEEEEEEECCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
LPTLIERKGTIINISSVAATYPYTGGNVYAGTKAFVKQFSLGLRSDLHGTGVRVTSIEPG
HHHHHHCCCCEEEEHHHEEECCCCCCCEECCHHHHHHHHHHHHHCCCCCCCEEEEEECCC
MAETEFTLVRTGGNQAASDALYRGAHPITAEDIAEQIFYVATLPPHLNINRLEIMPVNQS
CCCCEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHEEEEEECCCCCCCCEEEEEECCCC
FAGFQVARQQQSQLITPPHTLPTHSSGTSDK
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]