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The map label for this gene is speA

Identifier: 182680677

GI number: 182680677

Start: 144043

End: 145929

Strand: Direct

Name: speA

Synonym: XfasM23_0106

Alternate gene names: 182680677

Gene position: 144043-145929 (Clockwise)

Preceding gene: 182680675

Following gene: 182680682

Centisome position: 5.68

GC content: 53.84

Gene sequence:

>1887_bases
ATGACCTGGTCTCAAGATCTGGCCCACAAGACGTATTCGATCCGGCATTGGGCTGATGGGTATTTCGAGGTGAACGATGC
TGGGCACATGGTGGTGATGCCGCTCGGTGGGGATGGTGTGCGGATCTCGCTCCCAGAGGTTGTGGATGCTGCGCGTGCTG
CAGGTGCCAAGTTACCGCTGCTGCTGCGTTTCCCTGATATTTTGGGGCATCGTCTGGGTAAATTGCAGGCGGCGTTCGCT
CAGGCACAGTCCGAGTGGGAGTATGCAGGTGGTTACACTGCGGTTTACCCGATTAAGGTCAATCAGCATCGCGGTGTGGC
GGGTGTTCTGGCGAGTCACCAGGGGGATGGTTTCGGTTTGGAAGCCGGCAGCAAACCGGAATTGATGGCGGTGTTGGCGT
TATCGCGTCCGGGTGGGTTGATTGTTTGTAATGGGTATAAGGATCGGGAGTACATCCGTCTTGCGTTGATCGGACGCAAG
CTTGGTTTGAAGACTTTTATTGTGATTGAGAAGCCGTCTGAATTGAGAATGGTGCTTGAGGAGGCGAAAACGCTCGATGT
ATTGCCTGGTTTGGGCGTCCGGGTGCGTTTGGCGTCGTTGGGTGCCGGGAAATGGCAGAACAGCGGTGGCGATAAGGCAA
AGTTCGGTTTGTCGCCGCGTCAAGTGTTGGATGTATGGAAGGTGTTGCGTGGTACTGAGTATGCAGATTGTTTAAATGTG
ATGCATTTTCATATGGGGTCGCAGATCTCCAATGTGCGTGATATCGCTAAGGGGATGCGTGAGGCGACCCGTTACTTTGT
CGAGCTTTCGCGCTTGGGTGCGAAGATCACGCATGTGGATGTTGGTGGTGGTCTTGGCATTGATTACGAGGGCACGCGTT
CGCGTAGTGACTGTTCGATCAATTATGGTCTGCAGGCGTATGCCAGTCATATCGTGCAGCCGCTGGCGAGTGCGTGTGAG
GATTATGATTTGGTGCCGCCACGCATTGTCACGGAGTGTGGTCGTGCAATGACGGCGCATCATGCGGTGCTGATCGCTAA
TGTGACCGAGGTCGAAGCGGTGCCGGAGGGTCGGGTGCCAGGGGTGTGTGATGATGAGCCTGCGGTGGTTCGCCACATGC
GCGAGATTTACGGGGAGTTGGATGCGCGTCCGGCAATAGAGTTGTTTTATGAAGCACAGCACTTTCATGCTGAGGGATTG
GCGGCTTACACCCTCGGGCAGATTGATTTGGTGCATCGCGCACGTATTGATGATTTGTTTTATGCGATTTCGCATGGGGT
GCGGGAGCGTCTCAGTCACGAGGAGAAGAGTCACCGTCCGGTGTTGGATGAGCTGAATGAGCGCTTGGTTGATAAATATT
TTGTCAATTTCAGTGTGTTTGAGTCGATTCCGGATGTGTGGGCTATCAATCAAATTTTTCCGATTGTCCCCATTGAGCGT
TTGAACGAGGTACCGACCCGACGTGGTGTGGTCTGTGATTTGACCTGCGATTCAGATGGTACGGTCAAGCAGTATGTGGA
AAACGAGAGTCTGGACAGTGCGTTGCCTCTGCATGTGTTGCGTCATGGCGAGGCTTACAGGATTGGCTTTTTCCTTGTGG
GTGCTTATCAGGAAATCCTTGGCGATATCCATAATTTGTTTGGCGATACCGATGCGGTTGAGGTTGCAGTCGACGGCAGG
GGGTATCGTATTGCGCAGCAGCGTTGCGGTGATACGACCGATGTGATGTTGGACTATGTCGGTTATGCGCTTGATGAGGT
GCGCAGGGTTTATGCGCAACGTATTGCGGCGGCGGGGATGTCTGCTGCGGAGTCCAAGGCATTGAGCGATATGTTGGAAG
CCGGTCTGACGGGTTATCCCTATTTGTCAGATGTGCCGCTGGAGTGA

Upstream 100 bases:

>100_bases
TTTTGTGGTGGATGTGGCTGTGTGATGTGCATTCTAACGGTCGCTGGTATCCAAGGCTTGTAGAATGCGGCTCCTTTGGC
TTTATTGAAGATTTTTATCC

Downstream 100 bases:

>100_bases
GTGGGAAGTGTGTGGGGCGGGGTGATCAATTGTGATTGCTGTTGTCGTGCGACTTGGAAGCCAGCGAACGATTGGTTAAC
GGGCATGATCTCTAGCCGAT

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 628; Mature: 627

Protein sequence:

>628_residues
MTWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPLLLRFPDILGHRLGKLQAAFA
QAQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRK
LGLKTFIVIEKPSELRMVLEEAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNV
MHFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSINYGLQAYASHIVQPLASACE
DYDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVPGVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGL
AAYTLGQIDLVHRARIDDLFYAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIER
LNEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGR
GYRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGMSAAESKALSDMLEAGLTGYPYLSDVPLE

Sequences:

>Translated_628_residues
MTWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPLLLRFPDILGHRLGKLQAAFA
QAQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRK
LGLKTFIVIEKPSELRMVLEEAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNV
MHFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSINYGLQAYASHIVQPLASACE
DYDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVPGVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGL
AAYTLGQIDLVHRARIDDLFYAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIER
LNEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGR
GYRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGMSAAESKALSDMLEAGLTGYPYLSDVPLE
>Mature_627_residues
TWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPLLLRFPDILGHRLGKLQAAFAQ
AQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKL
GLKTFIVIEKPSELRMVLEEAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNVM
HFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSINYGLQAYASHIVQPLASACED
YDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVPGVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGLA
AYTLGQIDLVHRARIDDLFYAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIERL
NEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGRG
YRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGMSAAESKALSDMLEAGLTGYPYLSDVPLE

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=625, Percent_Identity=46.4, Blast_Score=555, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_XYLF2 (B2I6M1)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001828837.1
- ProteinModelPortal:   B2I6M1
- GeneID:   6203266
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0106
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- ProtClustDB:   PRK05354
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC; SSF50621 Racem_decarbox_C

EC number: =4.1.1.19

Molecular weight: Translated: 69215; Mature: 69084

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPL
CCCCHHHHHHHEEEEECCCCEEEECCCCCEEEEEECCCCEEEECHHHHHHHHHCCCCCCE
LLRFPDILGHRLGKLQAAFAQAQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGL
EEECHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEEEEEECCCCCHHHHHCCCCCCCCCC
EAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGLKTFIVIEKPSELRMVLE
CCCCCCCEEEEEEECCCCCEEEECCCCCCHHEEEEEHHHHCCCEEEEEEECCHHHHHHHH
EAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNV
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
MHFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEE
NYGLQAYASHIVQPLASACEDYDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVP
ECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEEECHHHHCCCCCCCC
GVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGLAAYTLGQIDLVHRARIDDLF
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHH
YAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIER
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHH
LNEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEIL
HHCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHH
GDIHNLFGDTDAVEVAVDGRGYRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGM
HHHHHHHCCCCEEEEEECCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAAESKALSDMLEAGLTGYPYLSDVPLE
CHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPL
CCCHHHHHHHEEEEECCCCEEEECCCCCEEEEEECCCCEEEECHHHHHHHHHCCCCCCE
LLRFPDILGHRLGKLQAAFAQAQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGL
EEECHHHHHHHHHHHHHHHHHHHHCCHHCCCEEEEEEEEECCCCCHHHHHCCCCCCCCCC
EAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGLKTFIVIEKPSELRMVLE
CCCCCCCEEEEEEECCCCCEEEECCCCCCHHEEEEEHHHHCCCEEEEEEECCHHHHHHHH
EAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNV
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
MHFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSI
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEE
NYGLQAYASHIVQPLASACEDYDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVP
ECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEEECHHHHCCCCCCCC
GVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGLAAYTLGQIDLVHRARIDDLF
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHHHHHHHH
YAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIER
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHH
LNEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEIL
HHCCCCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCHHHHHCCCEEEEHHHHHHHHHHHH
GDIHNLFGDTDAVEVAVDGRGYRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGM
HHHHHHHCCCCEEEEEECCCCEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAAESKALSDMLEAGLTGYPYLSDVPLE
CHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA