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The map label for this gene is aspC [H]

Identifier: 182680598

GI number: 182680598

Start: 32727

End: 33929

Strand: Direct

Name: aspC [H]

Synonym: XfasM23_0026

Alternate gene names: 182680598

Gene position: 32727-33929 (Clockwise)

Preceding gene: 182680596

Following gene: 182680600

Centisome position: 1.29

GC content: 52.04

Gene sequence:

>1203_bases
GTGCCCTTATTTACAGATGTGGAATTGGTTCCGGGTGATCCCATTCTGAGCCTCAACGATGCTTATAACGCCGATACGCG
TACCAACAAGGTCAATTTGGGTATTGGTATTTATTGTGACGAGAGCGGTTGTATCCCGCTGTTGCGGGCTGTCCAGCAGG
TTGAAGAGCAACTTGCGAAGCATCCGAAACCGCGCGGTTATCTGCCGATTGATGGTTTGCCAGCCTATATCAAAGCCACA
CAACAATTGTTGTTTGGAGTTGACTCCCTCTTGTTGACGGCTGGCCGTGTGGCGACTTCACAGACTGTTGGAGGTTCTGG
TGCATTGCGGGTGGCTGCTGAGGTACTGAAGCAGGTGCTACCGCATGCCACTGTGGCCATTAGCCGTCCAAGCTGGGAGA
ACCACCGTGCTTTGTTCACCGCTGCTGGCTTCAAGATTGAGGACTATACCTATTTCGATACGCTCGGCCACGCGGTGGAC
TTTACTGGAATGGTGGCGGACTTGGCGAAGCTGCAACCAAAGACCGTGGTATTACTTCATGGTTGCTGTCATAACCCAAC
GGGTGCCGATCTCAGCAGGGATCAGTGGAAGCAGCTTGTTGCCTTGTTCCAGGAACGTCAATTGCTGCCATGTATCGATC
TGGCTTACCAAGGATTCAATCAGGGCATTGATGCGGATGCTTATGCCATACGTTTGCTTGCCGAAGAAGGTATTAGTAAC
TATGTAGTTGCCAACTCGTACTCCAAATCGTTCTCGTTGTATGGCGAGCGTGTTGGAGGGCTGTCGATCGTTGCTTCCAA
TACTGAGCAAGCCCAAGCAATCCAGTCACAAGTAAAGCGTATCATCCGTACGATTTATTCCAGTCCGCCGGCACACGGTG
CCTACTTGGTCGCGGGTGTGCTGAACAGTCATGAATTACGCACGCTGTGGGAGCAGGAGTTAACTCAGATGCGTGAACGT
ATCCACGGGTTGCGTGCGGGTTTGGTTGCTCGATTGAAGGCGCTGGGTGCGCCGGAGTTTGATTTCATACAACGTCAAGC
AGGCATGTTTTCGTATTCGGGGTTGAGCAAGATCCAGGTGGATCGTTTACGCGACGAGTTCGGGATTTATGCGGTCAGTA
GTGGACGTATCTGTGTGGCTGCGTTGAGTCAGCACAAATTGGAATACGTGGCCCAGGCTGTGGTGAAGGTGCATCAAGGC
TGA

Upstream 100 bases:

>100_bases
ATTAGCCTTGCTGCCTTGTTACGATGCAACCGTTTGGGCGTACTGCGTAACTGTGCGGGGGCCTAAGTATTTTCTCCTTC
GTTTTCAGTGAGTACCCACC

Downstream 100 bases:

>100_bases
GATGTGGTTCTGTTTTCCGGAACAGTAGGTGCCTGCATCAAGTCGTATTAGAGTCAGACATCGGCGCGCTACATCATGGA
GGGTGTCTGGTGAAGCGCCA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MPLFTDVELVPGDPILSLNDAYNADTRTNKVNLGIGIYCDESGCIPLLRAVQQVEEQLAKHPKPRGYLPIDGLPAYIKAT
QQLLFGVDSLLLTAGRVATSQTVGGSGALRVAAEVLKQVLPHATVAISRPSWENHRALFTAAGFKIEDYTYFDTLGHAVD
FTGMVADLAKLQPKTVVLLHGCCHNPTGADLSRDQWKQLVALFQERQLLPCIDLAYQGFNQGIDADAYAIRLLAEEGISN
YVVANSYSKSFSLYGERVGGLSIVASNTEQAQAIQSQVKRIIRTIYSSPPAHGAYLVAGVLNSHELRTLWEQELTQMRER
IHGLRAGLVARLKALGAPEFDFIQRQAGMFSYSGLSKIQVDRLRDEFGIYAVSSGRICVAALSQHKLEYVAQAVVKVHQG

Sequences:

>Translated_400_residues
MPLFTDVELVPGDPILSLNDAYNADTRTNKVNLGIGIYCDESGCIPLLRAVQQVEEQLAKHPKPRGYLPIDGLPAYIKAT
QQLLFGVDSLLLTAGRVATSQTVGGSGALRVAAEVLKQVLPHATVAISRPSWENHRALFTAAGFKIEDYTYFDTLGHAVD
FTGMVADLAKLQPKTVVLLHGCCHNPTGADLSRDQWKQLVALFQERQLLPCIDLAYQGFNQGIDADAYAIRLLAEEGISN
YVVANSYSKSFSLYGERVGGLSIVASNTEQAQAIQSQVKRIIRTIYSSPPAHGAYLVAGVLNSHELRTLWEQELTQMRER
IHGLRAGLVARLKALGAPEFDFIQRQAGMFSYSGLSKIQVDRLRDEFGIYAVSSGRICVAALSQHKLEYVAQAVVKVHQG
>Mature_399_residues
PLFTDVELVPGDPILSLNDAYNADTRTNKVNLGIGIYCDESGCIPLLRAVQQVEEQLAKHPKPRGYLPIDGLPAYIKATQ
QLLFGVDSLLLTAGRVATSQTVGGSGALRVAAEVLKQVLPHATVAISRPSWENHRALFTAAGFKIEDYTYFDTLGHAVDF
TGMVADLAKLQPKTVVLLHGCCHNPTGADLSRDQWKQLVALFQERQLLPCIDLAYQGFNQGIDADAYAIRLLAEEGISNY
VVANSYSKSFSLYGERVGGLSIVASNTEQAQAIQSQVKRIIRTIYSSPPAHGAYLVAGVLNSHELRTLWEQELTQMRERI
HGLRAGLVARLKALGAPEFDFIQRQAGMFSYSGLSKIQVDRLRDEFGIYAVSSGRICVAALSQHKLEYVAQAVVKVHQG

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=397, Percent_Identity=41.0579345088161, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI4504067, Length=398, Percent_Identity=39.9497487437186, Blast_Score=279, Evalue=4e-75,
Organism=Homo sapiens, GI117414139, Length=382, Percent_Identity=26.9633507853403, Blast_Score=148, Evalue=9e-36,
Organism=Escherichia coli, GI1790488, Length=398, Percent_Identity=47.4874371859297, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=46.2121212121212, Blast_Score=375, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71981858, Length=399, Percent_Identity=38.3458646616541, Blast_Score=317, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI25147133, Length=396, Percent_Identity=37.3737373737374, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17569539, Length=398, Percent_Identity=38.1909547738693, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17569537, Length=370, Percent_Identity=31.8918918918919, Blast_Score=187, Evalue=8e-48,
Organism=Caenorhabditis elegans, GI17550384, Length=265, Percent_Identity=36.9811320754717, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI25147136, Length=211, Percent_Identity=36.0189573459716, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323055, Length=404, Percent_Identity=36.6336633663366, Blast_Score=271, Evalue=9e-74,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=30.2325581395349, Blast_Score=215, Evalue=9e-57,
Organism=Drosophila melanogaster, GI19922362, Length=398, Percent_Identity=39.4472361809045, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI24654046, Length=398, Percent_Identity=39.4472361809045, Blast_Score=298, Evalue=5e-81,
Organism=Drosophila melanogaster, GI24580970, Length=397, Percent_Identity=37.7833753148615, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24580972, Length=397, Percent_Identity=37.7833753148615, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=37.9487179487179, Blast_Score=290, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43752; Mature: 43620

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLFTDVELVPGDPILSLNDAYNADTRTNKVNLGIGIYCDESGCIPLLRAVQQVEEQLAK
CCCCCCCEECCCCCEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
HPKPRGYLPIDGLPAYIKATQQLLFGVDSLLLTAGRVATSQTVGGSGALRVAAEVLKQVL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHC
PHATVAISRPSWENHRALFTAAGFKIEDYTYFDTLGHAVDFTGMVADLAKLQPKTVVLLH
CCCEEEEECCCCCCCCEEEEECCEEEECEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GCCHNPTGADLSRDQWKQLVALFQERQLLPCIDLAYQGFNQGIDADAYAIRLLAEEGISN
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
YVVANSYSKSFSLYGERVGGLSIVASNTEQAQAIQSQVKRIIRTIYSSPPAHGAYLVAGV
EEEECCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEH
LNSHELRTLWEQELTQMRERIHGLRAGLVARLKALGAPEFDFIQRQAGMFSYSGLSKIQV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHH
DRLRDEFGIYAVSSGRICVAALSQHKLEYVAQAVVKVHQG
HHHHHHHCEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PLFTDVELVPGDPILSLNDAYNADTRTNKVNLGIGIYCDESGCIPLLRAVQQVEEQLAK
CCCCCCEECCCCCEEECCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHH
HPKPRGYLPIDGLPAYIKATQQLLFGVDSLLLTAGRVATSQTVGGSGALRVAAEVLKQVL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHC
PHATVAISRPSWENHRALFTAAGFKIEDYTYFDTLGHAVDFTGMVADLAKLQPKTVVLLH
CCCEEEEECCCCCCCCEEEEECCEEEECEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
GCCHNPTGADLSRDQWKQLVALFQERQLLPCIDLAYQGFNQGIDADAYAIRLLAEEGISN
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
YVVANSYSKSFSLYGERVGGLSIVASNTEQAQAIQSQVKRIIRTIYSSPPAHGAYLVAGV
EEEECCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEH
LNSHELRTLWEQELTQMRERIHGLRAGLVARLKALGAPEFDFIQRQAGMFSYSGLSKIQV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHH
DRLRDEFGIYAVSSGRICVAALSQHKLEYVAQAVVKVHQG
HHHHHHHCEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]