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The map label for this gene is argD [H]

Identifier: 182677151

GI number: 182677151

Start: 179901

End: 181118

Strand: Direct

Name: argD [H]

Synonym: Bind_0150

Alternate gene names: 182677151

Gene position: 179901-181118 (Clockwise)

Preceding gene: 182677150

Following gene: 182677152

Centisome position: 4.31

GC content: 62.23

Gene sequence:

>1218_bases
GTGACTTCGTCGCTGCTTCCCACCTATGCCAGGGCGCCGATTGCTTTCGAGCGGGGCGAGGGTGCTTGGCTGACCTCGAC
GACGGGTGAACGCTTTCTCGATTTCGGCGGCGGCATTGCCGTGGCGAGCCTTGGCTATAGCCATCCCCATCTCATCAAGG
CGCTTCATGAGCAGGGCGACAAGCTCTGGCATACGTCAAATCTGTTCCAGATTCCTCAGGCCGAACGCCTGGCTGAACGG
CTCACCGCCGTGAGTTTCGCCGATTTCGTCTTTTTCACCAATTCCGGTGCGGAGGCGATGGAAGGCGTGATCAAGACGGC
GCGCAAATATCATGCGGCCTGCGGCCATCCGGAAAAGAACCGCATCATCACGTTCCAGGGCGCGTTCCATGGCCGCACGC
TCGCGACCATCGCCGCCGCCGGCAATGAGAAATATCTTGACGGTTTCGAACCGCGTCTGCCGGGCTTCGACAATGTCCCC
TTCGGCGATCTTGAGGCGGTCAAGGCCGCGATCAAGCCCGAGACCGGCGCGATCCTGATTGAACCCATTCAGGGCGAGGG
CGGCATTCGTGTCGTCTCGCCGGATTTTCTGCAAGCCTTGCGCAAGCTCTGTGACGAACAGGGCCTGTTGCTCCTCTTGG
ACGAGGTCCAGAGCGGCGTCGGGCGCAGCGGCAAGCTCTTTGCCTATGAATGGGCGGGCGTGGAGCCGGATGTCATGGCG
ATTGCCAAGGGCATCGGCGGTGGTTTTCCGCTCGGTGCCTTCATGGCGACCCGGGAAGCCGCCAAGGGCATGGTCGTCGG
CACGCATGGTTCGACCTATGGGGGCAACCCTTTGGCGACGAGCATCGGCAATGCCGTGCTCGATATCGTGCTGGAACCGA
GCTTCCTCGCCCATGTCGAGGCCACCGGGGTGCTGTTGCAGCAAAGGCTCGTCGCTTTGCGGGAACGCCATCCAGAGGTG
ATCGCCGAATTGCGAGGCGCAGGTTTGATGCGTGGGATCAAGGTTACCCTTCCGGTCGCGGATTTCGCGGCGGCGGCACG
CGCCGAAAAGCTGCTCGTCATCCCGGCGGGCGATAATGTCGTGCGCCTCCTTCCGCCGCTCATCATTGGCGAAGAGGAAG
TGGATGGCGCGATCGAGCGTTTGGACGCGGCTTGCGCGGCGCTCAAAGCCCGAATCAACGCCAATAGCTCCTCTCTCCTG
AGCGGAGCCGCTGAATGA

Upstream 100 bases:

>100_bases
TTGATTTTTAGGCGTTTCGCACGCGAAGACGCGGGACCCCACGTCGGGCTTCCTGCCACATGCGTTGCACGCCTTGCTAT
CCAACTTCGCGGAGCCGCCA

Downstream 100 bases:

>100_bases
CGCCTCTCCCTGTGTCCGATCTCATCGTGCAGCCCAAACATTTTCTTGATTTGTCCCGGCTTGAAGCCAAGGATCTCCGC
GCTATTCTCGATTTGGCGGC

Product: acetylornithine and succinylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MTSSLLPTYARAPIAFERGEGAWLTSTTGERFLDFGGGIAVASLGYSHPHLIKALHEQGDKLWHTSNLFQIPQAERLAER
LTAVSFADFVFFTNSGAEAMEGVIKTARKYHAACGHPEKNRIITFQGAFHGRTLATIAAAGNEKYLDGFEPRLPGFDNVP
FGDLEAVKAAIKPETGAILIEPIQGEGGIRVVSPDFLQALRKLCDEQGLLLLLDEVQSGVGRSGKLFAYEWAGVEPDVMA
IAKGIGGGFPLGAFMATREAAKGMVVGTHGSTYGGNPLATSIGNAVLDIVLEPSFLAHVEATGVLLQQRLVALRERHPEV
IAELRGAGLMRGIKVTLPVADFAAAARAEKLLVIPAGDNVVRLLPPLIIGEEEVDGAIERLDAACAALKARINANSSSLL
SGAAE

Sequences:

>Translated_405_residues
MTSSLLPTYARAPIAFERGEGAWLTSTTGERFLDFGGGIAVASLGYSHPHLIKALHEQGDKLWHTSNLFQIPQAERLAER
LTAVSFADFVFFTNSGAEAMEGVIKTARKYHAACGHPEKNRIITFQGAFHGRTLATIAAAGNEKYLDGFEPRLPGFDNVP
FGDLEAVKAAIKPETGAILIEPIQGEGGIRVVSPDFLQALRKLCDEQGLLLLLDEVQSGVGRSGKLFAYEWAGVEPDVMA
IAKGIGGGFPLGAFMATREAAKGMVVGTHGSTYGGNPLATSIGNAVLDIVLEPSFLAHVEATGVLLQQRLVALRERHPEV
IAELRGAGLMRGIKVTLPVADFAAAARAEKLLVIPAGDNVVRLLPPLIIGEEEVDGAIERLDAACAALKARINANSSSLL
SGAAE
>Mature_404_residues
TSSLLPTYARAPIAFERGEGAWLTSTTGERFLDFGGGIAVASLGYSHPHLIKALHEQGDKLWHTSNLFQIPQAERLAERL
TAVSFADFVFFTNSGAEAMEGVIKTARKYHAACGHPEKNRIITFQGAFHGRTLATIAAAGNEKYLDGFEPRLPGFDNVPF
GDLEAVKAAIKPETGAILIEPIQGEGGIRVVSPDFLQALRKLCDEQGLLLLLDEVQSGVGRSGKLFAYEWAGVEPDVMAI
AKGIGGGFPLGAFMATREAAKGMVVGTHGSTYGGNPLATSIGNAVLDIVLEPSFLAHVEATGVLLQQRLVALRERHPEVI
AELRGAGLMRGIKVTLPVADFAAAARAEKLLVIPAGDNVVRLLPPLIIGEEEVDGAIERLDAACAALKARINANSSSLLS
GAAE

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=384, Percent_Identity=33.59375, Blast_Score=226, Evalue=2e-59,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=34.5637583892617, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=28.604118993135, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=26.2068965517241, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442705, Length=435, Percent_Identity=25.2873563218391, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=23.9080459770115, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226442709, Length=400, Percent_Identity=26, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI188536080, Length=423, Percent_Identity=26.7139479905437, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI38679950, Length=423, Percent_Identity=26.7139479905437, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI38679946, Length=423, Percent_Identity=26.7139479905437, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1788044, Length=394, Percent_Identity=43.9086294416244, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1789759, Length=388, Percent_Identity=42.0103092783505, Blast_Score=317, Evalue=9e-88,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=34.4303797468354, Blast_Score=227, Evalue=9e-61,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=34.9127182044888, Blast_Score=201, Evalue=9e-53,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=34.6534653465347, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1786991, Length=410, Percent_Identity=31.9512195121951, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1786349, Length=297, Percent_Identity=30.6397306397306, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI25144271, Length=378, Percent_Identity=32.8042328042328, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=30.5936073059361, Blast_Score=176, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=262, Percent_Identity=34.3511450381679, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=25.7611241217799, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=447, Percent_Identity=23.7136465324385, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71981843, Length=163, Percent_Identity=29.4478527607362, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=400, Percent_Identity=35.5, Blast_Score=258, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6323470, Length=409, Percent_Identity=31.0513447432763, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6324386, Length=413, Percent_Identity=23.9709443099274, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6321456, Length=431, Percent_Identity=26.2180974477958, Blast_Score=96, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21357415, Length=382, Percent_Identity=31.6753926701571, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI161085790, Length=439, Percent_Identity=30.2961275626424, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=29.8165137614679, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI21356575, Length=412, Percent_Identity=27.9126213592233, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI281366494, Length=424, Percent_Identity=25.9433962264151, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24667139, Length=424, Percent_Identity=25.9433962264151, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24667143, Length=424, Percent_Identity=25.9433962264151, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42879; Mature: 42747

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSLLPTYARAPIAFERGEGAWLTSTTGERFLDFGGGIAVASLGYSHPHLIKALHEQGD
CCCCCCCHHHCCCEEEECCCCCEEECCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCC
KLWHTSNLFQIPQAERLAERLTAVSFADFVFFTNSGAEAMEGVIKTARKYHAACGHPEKN
CEEECCCCEECCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
RIITFQGAFHGRTLATIAAAGNEKYLDGFEPRLPGFDNVPFGDLEAVKAAIKPETGAILI
CEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEE
EPIQGEGGIRVVSPDFLQALRKLCDEQGLLLLLDEVQSGVGRSGKLFAYEWAGVEPDVMA
EEECCCCCEEEECHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCEEEEECCCCCHHHHH
IAKGIGGGFPLGAFMATREAAKGMVVGTHGSTYGGNPLATSIGNAVLDIVLEPSFLAHVE
HHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHEECCHHHHHHH
ATGVLLQQRLVALRERHPEVIAELRGAGLMRGIKVTLPVADFAAAARAEKLLVIPAGDNV
HHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCEEEEECHHHHHHHHCCCEEEEEECCCCH
VRLLPPLIIGEEEVDGAIERLDAACAALKARINANSSSLLSGAAE
HHHCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
TSSLLPTYARAPIAFERGEGAWLTSTTGERFLDFGGGIAVASLGYSHPHLIKALHEQGD
CCCCCCHHHCCCEEEECCCCCEEECCCCHHHHHCCCCEEEEECCCCCHHHHHHHHHCCC
KLWHTSNLFQIPQAERLAERLTAVSFADFVFFTNSGAEAMEGVIKTARKYHAACGHPEKN
CEEECCCCEECCCHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
RIITFQGAFHGRTLATIAAAGNEKYLDGFEPRLPGFDNVPFGDLEAVKAAIKPETGAILI
CEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEEEE
EPIQGEGGIRVVSPDFLQALRKLCDEQGLLLLLDEVQSGVGRSGKLFAYEWAGVEPDVMA
EEECCCCCEEEECHHHHHHHHHHHCCCCEEEEEHHHHHCCCCCCCEEEEECCCCCHHHHH
IAKGIGGGFPLGAFMATREAAKGMVVGTHGSTYGGNPLATSIGNAVLDIVLEPSFLAHVE
HHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHEECCHHHHHHH
ATGVLLQQRLVALRERHPEVIAELRGAGLMRGIKVTLPVADFAAAARAEKLLVIPAGDNV
HHHHHHHHHHHHHHHCCHHHHHHHHCCHHHCCEEEEECHHHHHHHHCCCEEEEEECCCCH
VRLLPPLIIGEEEVDGAIERLDAACAALKARINANSSSLLSGAAE
HHHCCCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]