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The map label for this gene is 182677150

Identifier: 182677150

GI number: 182677150

Start: 179040

End: 179630

Strand: Direct

Name: 182677150

Synonym: Bind_0149

Alternate gene names: NA

Gene position: 179040-179630 (Clockwise)

Preceding gene: 182677149

Following gene: 182677151

Centisome position: 4.29

GC content: 62.27

Gene sequence:

>591_bases
ATGGTTGTCTTGACGAGAATCTATACCCGTGGCGGCGATGGTGGGACGACCTCTCTGGGGACCGGCGAGAGGCGTAAGAA
ACAGGATTTGCGGATCGAAACTTACGGCACTGTCGATGAGGCCAATGCCTGCATCGGTCTTGCCCGGATCCATACCGCCA
GCGAGGCGGCTCACGCCAAGCTCGACGCCATGCTTTTATGCATCCAGAACGATCTGTTTGATCTCGGCGCCGATCTCTGC
ATGCCGGAAAATACCGCGGCCAATCCCAAGGTTGAGGCTTTGCGCATTCTGCCGGCCCAGGTTGAGAGGCTGGAACGCGA
CATCGATACGATCAATGCAGGGCTCGAGCCTTTGTCCTCCTTTGTCCTTCCGGGGGGCACACCGGCGGCGGCGGCGCTGC
ATCTCGCGCGCACCGTTGCGCGGCGCGCCGAACGCCTGCTGTGCGCTTTGCGGGAGACGCCGGGCGAGAGTGTGGGCGCA
CCAACGCTGGCCTATCTCAATCGGCTCTCGGATTTCCTGTTCGTTGCGGCGCGTCATGTCAATCAGCAGGGCGCGGGGGA
CGTGCTCTGGGTGCCGGGCTTGAACCGATGA

Upstream 100 bases:

>100_bases
GGCCTTCAATTCGTGGCGATCCTGATCATTCTTGGCGTGCTTTTGTACCGGGAAGGGATTTGAGGAGAGGCCATCGACGG
CTCCAGGAGGGACGAATGCT

Downstream 100 bases:

>100_bases
TCTCGCCTCGAGGCGTTCATAATTTACGACAGGACGATGAAATAACCTCCTTTTTTCCAGAAAAACCTTTGCCTTTAAAG
AAAATCACGTAAAATTTCGG

Product: ATP--cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVVLTRIYTRGGDGGTTSLGTGERRKKQDLRIETYGTVDEANACIGLARIHTASEAAHAKLDAMLLCIQNDLFDLGADLC
MPENTAANPKVEALRILPAQVERLERDIDTINAGLEPLSSFVLPGGTPAAAALHLARTVARRAERLLCALRETPGESVGA
PTLAYLNRLSDFLFVAARHVNQQGAGDVLWVPGLNR

Sequences:

>Translated_196_residues
MVVLTRIYTRGGDGGTTSLGTGERRKKQDLRIETYGTVDEANACIGLARIHTASEAAHAKLDAMLLCIQNDLFDLGADLC
MPENTAANPKVEALRILPAQVERLERDIDTINAGLEPLSSFVLPGGTPAAAALHLARTVARRAERLLCALRETPGESVGA
PTLAYLNRLSDFLFVAARHVNQQGAGDVLWVPGLNR
>Mature_196_residues
MVVLTRIYTRGGDGGTTSLGTGERRKKQDLRIETYGTVDEANACIGLARIHTASEAAHAKLDAMLLCIQNDLFDLGADLC
MPENTAANPKVEALRILPAQVERLERDIDTINAGLEPLSSFVLPGGTPAAAALHLARTVARRAERLLCALRETPGESVGA
PTLAYLNRLSDFLFVAARHVNQQGAGDVLWVPGLNR

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=176, Percent_Identity=38.6363636363636, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI115534154, Length=167, Percent_Identity=32.3353293413174, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 21025; Mature: 21025

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVLTRIYTRGGDGGTTSLGTGERRKKQDLRIETYGTVDEANACIGLARIHTASEAAHAK
CEEEEEEEECCCCCCCCCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LDAMLLCIQNDLFDLGADLCMPENTAANPKVEALRILPAQVERLERDIDTINAGLEPLSS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
FVLPGGTPAAAALHLARTVARRAERLLCALRETPGESVGAPTLAYLNRLSDFLFVAARHV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NQQGAGDVLWVPGLNR
CCCCCCCEEECCCCCC
>Mature Secondary Structure
MVVLTRIYTRGGDGGTTSLGTGERRKKQDLRIETYGTVDEANACIGLARIHTASEAAHAK
CEEEEEEEECCCCCCCCCCCCCCHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LDAMLLCIQNDLFDLGADLCMPENTAANPKVEALRILPAQVERLERDIDTINAGLEPLSS
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
FVLPGGTPAAAALHLARTVARRAERLLCALRETPGESVGAPTLAYLNRLSDFLFVAARHV
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NQQGAGDVLWVPGLNR
CCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]