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The map label for this gene is soxB2 [H]

Identifier: 17545820

GI number: 17545820

Start: 1157587

End: 1158831

Strand: Direct

Name: soxB2 [H]

Synonym: RSc1101

Alternate gene names: 17545820

Gene position: 1157587-1158831 (Clockwise)

Preceding gene: 17545819

Following gene: 17545821

Centisome position: 31.15

GC content: 66.67

Gene sequence:

>1245_bases
ATGAGCCGCTACTCGATATTCAACCTGTTCCGCAACGGCCTGTCGTACCACCAGCACTGGGAGCGGCAGTGGAAGAGTCC
TGAGCCGAAGCGCGAGTACGACGTCGTGATCGTCGGCGGCGGCGGGCACGGCCTGGCAACCGCGTACTACCTCGCGAAGG
AGCACGGCATCACCAACGTCGCGGTGCTCGAGAAGGGCTGGATCGGCGGCGGCAATACCGCGCGCAACACGACGATCGTG
CGCTCGAACTATCTGTGGGACGAATCGGCCGCGCTGTACGAGAAGGCGATGAAGCTGTGGGAAGGGCTGTCGCAGGACCT
GAACTACAACGTGATGTTCAGCCAGCGCGGCGTGATGAACCTCGCGCACACGCTGCAGGACGTGCGCGACACCGAGCGCC
GCGTGAACGCGAACCGGCTGAACGGCGTCGACGCCGAATTCCTGACGCCTGCGCAGATCAAGGCCATCGAGCCGACGATC
AACCTGAACAGCCGCTACCCGGTGCTCGGCGCATCGATCCAGCGGCGCGCTGGCGTCGCCCGGCATGACGCGGTGGCGTG
GGGCTTCGCGCGCGGCGCGGACCGTGCGGGTGTCGACATCGTCCAGAACTGCCAGGTGACGGGCATCCGCCGCGAAGGCG
GCCAGGTCGTGGGCGTCGATACGGTGAAGGGCTTCATCAAGGCGAAGAAGGTCGCGGTGGTCGCGGCCGGCAATACGACC
ACGCTGGCCGACATGGCCGGCATCCGCCTGCCGATCGAAAGCCATCCGCTGCAGGCGCTGGTGTCGGAGCCGATCAAGCC
CGTCGTCAACTCGGTGATCATGTCGAACGCGGTGCACGCCTACATCAGCCAGTCCGACAAGGGCGACCTCGTGATCGGCG
CGGGCATCGACCAGTACACGGGCTTTGGCCAGCGCGGCAGCTTCCACATCATCGAAGGCACGCTGCAGGCCATTGTCGAG
ATGTTTCCGGTGTTCTCGCGCGTGCGGATGAACCGCCAGTGGGGCGGCATCGTCGATGTGTCGCCGGACGCGTGCCCGAT
CATCGGCAAGACCGACGTGAAGGGCCTGTACTTCAACTGCGGCTGGGGCACGGGCGGCTTCAAGGCGACGCCGGGCTCGG
GCTGGGTGTTCGCGCACACGATCGCGCGCGACGAGCCGCATCCGCTGAACGCGCCGTTCGCGCTTGAGCGCTTCTATACG
GGGCACCTGATCGACGAGCACGGCGCCGCCGCCGTCGCGCACTGA

Upstream 100 bases:

>100_bases
ATGCGCGAGACGAGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGCCTGGCCGTGAACGTCATCGAATG
CTAACGAAGGGTCCATCAGC

Downstream 100 bases:

>100_bases
ACCCGACCACCACCAGGAGAAGGAAACATGCTGCTGATCGAATGTCCGTGGTGCGGGCCGCGCGCCGAATCCGAGTTCAC
GTGCGGCGGCGAAGCCGACA

Product: sarcosine oxidase subunit beta

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSRYSIFNLFRNGLSYHQHWERQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAVLEKGWIGGGNTARNTTIV
RSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKAIEPTI
NLNSRYPVLGASIQRRAGVARHDAVAWGFARGADRAGVDIVQNCQVTGIRREGGQVVGVDTVKGFIKAKKVAVVAAGNTT
TLADMAGIRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFHIIEGTLQAIVE
MFPVFSRVRMNRQWGGIVDVSPDACPIIGKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFALERFYT
GHLIDEHGAAAVAH

Sequences:

>Translated_414_residues
MSRYSIFNLFRNGLSYHQHWERQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAVLEKGWIGGGNTARNTTIV
RSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKAIEPTI
NLNSRYPVLGASIQRRAGVARHDAVAWGFARGADRAGVDIVQNCQVTGIRREGGQVVGVDTVKGFIKAKKVAVVAAGNTT
TLADMAGIRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFHIIEGTLQAIVE
MFPVFSRVRMNRQWGGIVDVSPDACPIIGKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFALERFYT
GHLIDEHGAAAVAH
>Mature_413_residues
SRYSIFNLFRNGLSYHQHWERQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNVAVLEKGWIGGGNTARNTTIVR
SNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMNLAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKAIEPTIN
LNSRYPVLGASIQRRAGVARHDAVAWGFARGADRAGVDIVQNCQVTGIRREGGQVVGVDTVKGFIKAKKVAVVAAGNTTT
LADMAGIRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYTGFGQRGSFHIIEGTLQAIVEM
FPVFSRVRMNRQWGGIVDVSPDACPIIGKTDVKGLYFNCGWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFALERFYTG
HLIDEHGAAAVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=394, Percent_Identity=24.1116751269036, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI21361378, Length=394, Percent_Identity=24.1116751269036, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24797151, Length=397, Percent_Identity=23.1738035264484, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI194306651, Length=382, Percent_Identity=23.0366492146597, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787438, Length=330, Percent_Identity=23.9393939393939, Blast_Score=68, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20130091, Length=383, Percent_Identity=23.4986945169713, Blast_Score=82, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45236; Mature: 45105

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYSIFNLFRNGLSYHQHWERQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNV
CCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEE
AVLEKGWIGGGNTARNTTIVRSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMN
EEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
LAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKAIEPTINLNSRYPVLGASIQRRAGVA
HHHHHHHHHHHHHHCCCHHCCCCCCHHCCCCCEEEECCEEECCCCCCCCCCHHHHHCCCC
RHDAVAWGFARGADRAGVDIVQNCQVTGIRREGGQVVGVDTVKGFIKAKKVAVVAAGNTT
HHHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCEEEEHHHHHHHHEEEEEEEEECCCCE
TLADMAGIRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYT
EHHHHCCEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHC
GFGQRGSFHIIEGTLQAIVEMFPVFSRVRMNRQWGGIVDVSPDACPIIGKTDVKGLYFNC
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCCCEEEEEC
GWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFALERFYTGHLIDEHGAAAVAH
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCEECCCCCEECCC
>Mature Secondary Structure 
SRYSIFNLFRNGLSYHQHWERQWKSPEPKREYDVVIVGGGGHGLATAYYLAKEHGITNV
CCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEE
AVLEKGWIGGGNTARNTTIVRSNYLWDESAALYEKAMKLWEGLSQDLNYNVMFSQRGVMN
EEEECCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
LAHTLQDVRDTERRVNANRLNGVDAEFLTPAQIKAIEPTINLNSRYPVLGASIQRRAGVA
HHHHHHHHHHHHHHCCCHHCCCCCCHHCCCCCEEEECCEEECCCCCCCCCCHHHHHCCCC
RHDAVAWGFARGADRAGVDIVQNCQVTGIRREGGQVVGVDTVKGFIKAKKVAVVAAGNTT
HHHHHHHHHHCCCCCCCCHHHCCCEEEEEECCCCEEEEHHHHHHHHEEEEEEEEECCCCE
TLADMAGIRLPIESHPLQALVSEPIKPVVNSVIMSNAVHAYISQSDKGDLVIGAGIDQYT
EHHHHCCEECCCCCCCHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCEEEECCCHHHC
GFGQRGSFHIIEGTLQAIVEMFPVFSRVRMNRQWGGIVDVSPDACPIIGKTDVKGLYFNC
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCCCEEEEEC
GWGTGGFKATPGSGWVFAHTIARDEPHPLNAPFALERFYTGHLIDEHGAAAVAH
CCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]