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The map label for this gene is sda2b [H]

Identifier: 17545819

GI number: 17545819

Start: 1157238

End: 1157570

Strand: Direct

Name: sda2b [H]

Synonym: RSc1100

Alternate gene names: 17545819

Gene position: 1157238-1157570 (Clockwise)

Preceding gene: 17545818

Following gene: 17545820

Centisome position: 31.14

GC content: 65.77

Gene sequence:

>333_bases
GTGGCGTGCTCGATGGCCGCGGCCGCGCTCGCCGCCGTGATGGGCGGCACCCCCGACCAGGTCGAGAACGCCGCGGAGAT
CGGCATGGAGCACAACCTCGGCATGACCTGCGATCCGGTCGGCGGCCTGGTGCAGATTCCCTGCATCGAGCGCAACGCGA
TGGGCGCGATCAAGGCGCTGAACGCATCACGCATGGCGCTCAAGGGCGACGGCACGCACTACGTGTCGCTCGATTCGGTC
ATCAAGACGATGCGCGAGACGAGCGCCGACATGAAGACGAAATACAAGGAAACGTCGCGCGGCGGCCTGGCCGTGAACGT
CATCGAATGCTAA

Upstream 100 bases:

>100_bases
TCGCATATCGAAGACGCCAATCGCCGCGGCGATCGGGATCATCTACAAGGAAACCGCGTCGATCTTCGGCGCCGAAGTCG
GCTGCCAGGGTGAGGTTGGC

Downstream 100 bases:

>100_bases
CGAAGGGTCCATCAGCATGAGCCGCTACTCGATATTCAACCTGTTCCGCAACGGCCTGTCGTACCACCAGCACTGGGAGC
GGCAGTGGAAGAGTCCTGAG

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 110; Mature: 109

Protein sequence:

>110_residues
MACSMAAAALAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKGDGTHYVSLDSV
IKTMRETSADMKTKYKETSRGGLAVNVIEC

Sequences:

>Translated_110_residues
MACSMAAAALAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKGDGTHYVSLDSV
IKTMRETSADMKTKYKETSRGGLAVNVIEC
>Mature_109_residues
ACSMAAAALAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKALNASRMALKGDGTHYVSLDSVI
KTMRETSADMKTKYKETSRGGLAVNVIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=107, Percent_Identity=66.3551401869159, Blast_Score=149, Evalue=5e-38,
Organism=Escherichia coli, GI48994925, Length=108, Percent_Identity=65.7407407407407, Blast_Score=148, Evalue=8e-38,
Organism=Escherichia coli, GI1789161, Length=110, Percent_Identity=62.7272727272727, Blast_Score=144, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 11462; Mature: 11331

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
8.2 %Met     (Translated Protein)
11.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
7.3 %Met     (Mature Protein)
11.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACSMAAAALAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKAL
CCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHC
NASRMALKGDGTHYVSLDSVIKTMRETSADMKTKYKETSRGGLAVNVIEC
CCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
ACSMAAAALAAVMGGTPDQVENAAEIGMEHNLGMTCDPVGGLVQIPCIERNAMGAIKAL
CCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHC
NASRMALKGDGTHYVSLDSVIKTMRETSADMKTKYKETSRGGLAVNVIEC
CCCCEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]