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The map label for this gene is pgsA [H]

Identifier: 17545791

GI number: 17545791

Start: 1125524

End: 1126099

Strand: Direct

Name: pgsA [H]

Synonym: RSc1072

Alternate gene names: 17545791

Gene position: 1125524-1126099 (Clockwise)

Preceding gene: 17545790

Following gene: 17545792

Centisome position: 30.29

GC content: 64.93

Gene sequence:

>576_bases
ATGCCTTTCAACTTCCCGATCCTCCTGACCTGGCTGCGGGTCGCCATGATCCCGCTGGTGGTGGGCGTGTTCTACGTGCC
GGATGCCTGGATGGCGCCGCCCGTCAAGAACCTGACCGCCGCGGCGTTCTTCATCGTTGCGAGCCTGACCGACTGGTTCG
ACGGATTCCTGGCGCGCCGCTGGAACCAGACTTCGGCGTTCGGCGCCTTCCTGGACCCGGTCGCCGACAAGCTGATGGTG
GCCGCTGCGTTGCTGGTGCTGCTGGCGCTTGGCCGTGTGTCGGACGTCATCGCGCTCGTCATCATCGGCCGCGAGATCAC
CATCTCGGCGCTGCGCGAGTGGATGGCGCAGATCGGTGCCTCACGCAGCGTTGCGGTCAACTTCCTCGGCAAGCTGAAGA
CGACCTTCCAGATGGTCGCGATTCCGCTGCTGCTGTTCGAGGGCCGCCTGTTCGATGTGGTCGATGCGCGGGTGTGGGGG
GCGTGGCTGATCTATGTGGCTGCGGTGCTGACGCTGTGGTCGATGGCGTACTACATGAAGCTGGCCTGGCCGCAGATCCG
GGAGCGCTCGAAATGA

Upstream 100 bases:

>100_bases
TGGCCGAAGAAATCTACCGCCAATTGCACTGATCGGCGACAATGGCCCCTCGTGCCGCGCCGGGGCTGGAACCGCGCGGC
GGTTGTCCTGTCGACTAGCC

Downstream 100 bases:

>100_bases
GCCCGCAAAAAACTTTTGCGCAAAGGTGTTGACGAGGACCATTCTTTTTTGCCATAATTTCGTTCTCGCGTTGCACTGAA
CGTAACGCGAAAGACCGGTG

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase transmembrane protein

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MPFNFPILLTWLRVAMIPLVVGVFYVPDAWMAPPVKNLTAAAFFIVASLTDWFDGFLARRWNQTSAFGAFLDPVADKLMV
AAALLVLLALGRVSDVIALVIIGREITISALREWMAQIGASRSVAVNFLGKLKTTFQMVAIPLLLFEGRLFDVVDARVWG
AWLIYVAAVLTLWSMAYYMKLAWPQIRERSK

Sequences:

>Translated_191_residues
MPFNFPILLTWLRVAMIPLVVGVFYVPDAWMAPPVKNLTAAAFFIVASLTDWFDGFLARRWNQTSAFGAFLDPVADKLMV
AAALLVLLALGRVSDVIALVIIGREITISALREWMAQIGASRSVAVNFLGKLKTTFQMVAIPLLLFEGRLFDVVDARVWG
AWLIYVAAVLTLWSMAYYMKLAWPQIRERSK
>Mature_190_residues
PFNFPILLTWLRVAMIPLVVGVFYVPDAWMAPPVKNLTAAAFFIVASLTDWFDGFLARRWNQTSAFGAFLDPVADKLMVA
AALLVLLALGRVSDVIALVIIGREITISALREWMAQIGASRSVAVNFLGKLKTTFQMVAIPLLLFEGRLFDVVDARVWGA
WLIYVAAVLTLWSMAYYMKLAWPQIRERSK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=184, Percent_Identity=51.6304347826087, Blast_Score=156, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21397; Mature: 21266

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFNFPILLTWLRVAMIPLVVGVFYVPDAWMAPPVKNLTAAAFFIVASLTDWFDGFLARR
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVAAALLVLLALGRVSDVIALVIIGREITISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SRSVAVNFLGKLKTTFQMVAIPLLLFEGRLFDVVDARVWGAWLIYVAAVLTLWSMAYYMK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAWPQIRERSK
HHCHHHHCCCC
>Mature Secondary Structure 
PFNFPILLTWLRVAMIPLVVGVFYVPDAWMAPPVKNLTAAAFFIVASLTDWFDGFLARR
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WNQTSAFGAFLDPVADKLMVAAALLVLLALGRVSDVIALVIIGREITISALREWMAQIGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
SRSVAVNFLGKLKTTFQMVAIPLLLFEGRLFDVVDARVWGAWLIYVAAVLTLWSMAYYMK
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAWPQIRERSK
HHCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]