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The map label for this gene is tdcB [H]

Identifier: 17545667

GI number: 17545667

Start: 995876

End: 996880

Strand: Direct

Name: tdcB [H]

Synonym: RSc0948

Alternate gene names: 17545667

Gene position: 995876-996880 (Clockwise)

Preceding gene: 17545664

Following gene: 17545669

Centisome position: 26.8

GC content: 70.05

Gene sequence:

>1005_bases
ATGCCGTCGATCGCCAATGCCGCTTCGCTCAATCGTGCCGCTGAACTGCGCCGTCTGCGCGCGGCTGCCGCCGTTGTCAA
TGCCGTGATCCCGCCGACGCCGCAGTACTGCTGGCCGCTGTTGTCGCAGGCGCTGGGGGCTGCCGTGTGGGTCAAGCACG
AGAACCATACGGAAGTGGGCGCCTTCAAGGTGCGCGGCGGGCTGAACTATCTGCACGCCTTGCGTCGTCGCGATCCGGAA
CTGCGCGGCGTGATCGCGGCGACACGCGGCAACCATGGGCAGTCGATCGCCCTGGCGGCGCGCAAGCAAGGCATGTCGGC
CACCATCGTGGTGCCCCACGGCAACAGCGTGGAAAAGAACGCCGCCATGCGCGCGCTCGGCGCCGAACTGGTCGAAGCCG
GCGAAGACTTCCAGGCGAGCCGCGAAGCCGCGGCAAGGCAGGCCGCCGAGCGCGGCCTGCACCTGGTGCCGGCCTTCCAC
GAAGACCTGGTGGCCGGGGTGGCCAGCTATTGGCTGGAGTTTTTCGAGGAGGCCGCGCCGCTGGACGTGGTCTACGTGCC
GATCGGCATGGGCTCGGGCATCTGCGCGGCGGCGGCGGCGCGCGATGCGTTCCGGCTGTCGACGCGCATCATCGGCGTGG
TGTCGGCGCATGCGCGATGCTATGACTACTCGTTCAATTGCGGCGCGCCGATTTCCGCGCCGGTATCGACGCAACTGGCC
GACGGCCTGGCATGCCGGACGCCGGATGCGACGGCGCTGGAGGTGATCCGCGCGGGCGTCGACGAAATCGTCACGGTGAC
GGACGACGAAGTCGCCGAGGCCATCCGCCTGTACTTCTCCACCACGCACAACATTGCGGAGGGTGCCGCCGCCGCGGCCC
TGGCGGCGGCCTGGCAGCAGCGCGACCAGTTGGCCGGCCTGCGCGTCGGCCTGCCGCTGACCGGCGGCAACATCGACCGC
GCCACGCTGGCGCGGGTGCTGGCCGGTCAGCCGATCGGCGCTTAA

Upstream 100 bases:

>100_bases
CGGAACAGTTTGACCGACAAATCGCGGAATTGTCGATGTCGCCGGCGGTGGCGGGCTGGGAAGATCGGGCCATCTTCCGA
ACTGTCCGCAGGAGCCCGCC

Downstream 100 bases:

>100_bases
GCCGGCTGCTGGCGGCGGCGCTGTACCAGCCAGCCGCCGCCGAGCACCACCATGAACACGATCGCGTAGACCGCCCACGC
CAGCAGGGGCTGTTCGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MPSIANAASLNRAAELRRLRAAAAVVNAVIPPTPQYCWPLLSQALGAAVWVKHENHTEVGAFKVRGGLNYLHALRRRDPE
LRGVIAATRGNHGQSIALAARKQGMSATIVVPHGNSVEKNAAMRALGAELVEAGEDFQASREAAARQAAERGLHLVPAFH
EDLVAGVASYWLEFFEEAAPLDVVYVPIGMGSGICAAAAARDAFRLSTRIIGVVSAHARCYDYSFNCGAPISAPVSTQLA
DGLACRTPDATALEVIRAGVDEIVTVTDDEVAEAIRLYFSTTHNIAEGAAAAALAAAWQQRDQLAGLRVGLPLTGGNIDR
ATLARVLAGQPIGA

Sequences:

>Translated_334_residues
MPSIANAASLNRAAELRRLRAAAAVVNAVIPPTPQYCWPLLSQALGAAVWVKHENHTEVGAFKVRGGLNYLHALRRRDPE
LRGVIAATRGNHGQSIALAARKQGMSATIVVPHGNSVEKNAAMRALGAELVEAGEDFQASREAAARQAAERGLHLVPAFH
EDLVAGVASYWLEFFEEAAPLDVVYVPIGMGSGICAAAAARDAFRLSTRIIGVVSAHARCYDYSFNCGAPISAPVSTQLA
DGLACRTPDATALEVIRAGVDEIVTVTDDEVAEAIRLYFSTTHNIAEGAAAAALAAAWQQRDQLAGLRVGLPLTGGNIDR
ATLARVLAGQPIGA
>Mature_333_residues
PSIANAASLNRAAELRRLRAAAAVVNAVIPPTPQYCWPLLSQALGAAVWVKHENHTEVGAFKVRGGLNYLHALRRRDPEL
RGVIAATRGNHGQSIALAARKQGMSATIVVPHGNSVEKNAAMRALGAELVEAGEDFQASREAAARQAAERGLHLVPAFHE
DLVAGVASYWLEFFEEAAPLDVVYVPIGMGSGICAAAAARDAFRLSTRIIGVVSAHARCYDYSFNCGAPISAPVSTQLAD
GLACRTPDATALEVIRAGVDEIVTVTDDEVAEAIRLYFSTTHNIAEGAAAAALAAAWQQRDQLAGLRVGLPLTGGNIDRA
TLARVLAGQPIGA

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=298, Percent_Identity=30.2013422818792, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI19923959, Length=261, Percent_Identity=28.3524904214559, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1790207, Length=290, Percent_Identity=27.9310344827586, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789505, Length=290, Percent_Identity=30.6896551724138, Blast_Score=108, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71991565, Length=318, Percent_Identity=27.9874213836478, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17537387, Length=292, Percent_Identity=31.1643835616438, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508781, Length=280, Percent_Identity=27.1428571428571, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322631, Length=310, Percent_Identity=31.9354838709677, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320930, Length=259, Percent_Identity=32.046332046332, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355833, Length=288, Percent_Identity=30.2083333333333, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24645328, Length=219, Percent_Identity=30.1369863013699, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 1344 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 35078; Mature: 34947

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSIANAASLNRAAELRRLRAAAAVVNAVIPPTPQYCWPLLSQALGAAVWVKHENHTEVG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCC
AFKVRGGLNYLHALRRRDPELRGVIAATRGNHGQSIALAARKQGMSATIVVPHGNSVEKN
EEEECCCHHHHHHHHHCCCHHHEEEEEECCCCCCEEEEEHHHCCCEEEEEEECCCCCHHH
AAMRALGAELVEAGEDFQASREAAARQAAERGLHLVPAFHEDLVAGVASYWLEFFEEAAP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHCCC
LDVVYVPIGMGSGICAAAAARDAFRLSTRIIGVVSAHARCYDYSFNCGAPISAPVSTQLA
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHH
DGLACRTPDATALEVIRAGVDEIVTVTDDEVAEAIRLYFSTTHNIAEGAAAAALAAAWQQ
CCCCCCCCCHHHHHHHHHCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDQLAGLRVGLPLTGGNIDRATLARVLAGQPIGA
HHHHCCEEEECEECCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PSIANAASLNRAAELRRLRAAAAVVNAVIPPTPQYCWPLLSQALGAAVWVKHENHTEVG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCC
AFKVRGGLNYLHALRRRDPELRGVIAATRGNHGQSIALAARKQGMSATIVVPHGNSVEKN
EEEECCCHHHHHHHHHCCCHHHEEEEEECCCCCCEEEEEHHHCCCEEEEEEECCCCCHHH
AAMRALGAELVEAGEDFQASREAAARQAAERGLHLVPAFHEDLVAGVASYWLEFFEEAAP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHHHCCC
LDVVYVPIGMGSGICAAAAARDAFRLSTRIIGVVSAHARCYDYSFNCGAPISAPVSTQLA
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCHHHHH
DGLACRTPDATALEVIRAGVDEIVTVTDDEVAEAIRLYFSTTHNIAEGAAAAALAAAWQQ
CCCCCCCCCHHHHHHHHHCHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDQLAGLRVGLPLTGGNIDRATLARVLAGQPIGA
HHHHCCEEEECEECCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA