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The map label for this gene is ybhO [H]

Identifier: 17545189

GI number: 17545189

Start: 501368

End: 502636

Strand: Direct

Name: ybhO [H]

Synonym: RSc0470

Alternate gene names: 17545189

Gene position: 501368-502636 (Clockwise)

Preceding gene: 17545188

Following gene: 17545190

Centisome position: 13.49

GC content: 71.79

Gene sequence:

>1269_bases
ATGAAGGTCGCGCGCGATGCCGGGCCGTTGCGTTCGGAGTGGCGGCGGGGCAAGCCCCTGCCGGGCAACCGGATCGACCT
GCTGCACGGCGGCGCCGCGTTCTTTCCCGCGCTGATCGAAGCCATCGATGCCGCGCGCCGCCGCATCGCGCTGGAAACCT
ACATCTATATCGACGACGACACCGGGCGCCGCGTGACCGAGGCGCTGGCGCGCGCGGCGCGGCGCGGCGTGGACGTGCGC
GTCACCGTGGACGGCTTTGGTACCGGCACGCTGCCCGCCGGCATCGCGGCGATGCTGGATGCGGCCGGCGCGGCCTGGCG
GGTGTACCGGCCGGTGCGCGGCTTTCGCCTGCAGCGCCGCTACCTGCGCCGCCTGCATCGCAAGGTCGCCGTGATCGATG
ACGAGGTGGCGTTCGTCGGCGGCATCAACATCATCGACGACCTGAACCACACCCCGTTCCGCGACGACGCACTGGGTGCC
CGCTATGACTTCGCCGTGCGCGTGCGCGGGCCGCTGGTCGGCCAGATCGCGCTGATGGTCGACCGGCTGTGGTGGCAGAC
GGGCCTGCTCGCCGGCGTGCGCGAGGTGGGCGTGACCGGCGTGGCCGCCGAGTTTCCGGTGATGACCGACACGCCCAAGC
CGGGGCGGCGCGGTGCCTCGGGGACGCAGCACGATCAGGCGCCGGACAACGTGCTGGCGTCGCTGGTGCTGCGCGACAAC
GTGCGCAACCGCCGCGCCATCGAGCGCGAGTACCTGCGCGCGCTGGGCACGGCGCGGCACGAGGTGATCATCGCCAATGC
CTATTTCCTGCCGGGCGTGCGCTTCATGCGCGCGCTGGCCGCGTGCCGGCGCCGCGGCGTGCGGGTGCGCATGCTGCTGC
AGGGCCATGTCGAATATGCGGTGCAGCATTACGCAACGCGTTCGCTGTATCACATGCTGCTGCGCGACGGCGTGGAGATC
CACGAATACACGGCCAGCTTCCTGCACGCCAAGGTCGCGGTCGTGGATGGGCGCTGGGCGACGGTGGGTTCGAGCAACAT
CGATCCGTTCAGCCTGCTGCTGGCGCGCGAAGCCAACGTGGTCGCCTGGGACGCGGGGGTCGCCGGGCAGCTGCGCGCCG
CGCTGGAAGACGCCATTGCGCGCCATGCGCGGCCGATCCTCGCCGATGCGCATGCGGCCCGGCCCTGGTGGTGGCGCGTG
GTCGACTGGTGCGCGTATCGGCTGGTGCGGCTGGGCGTCGTCATCAGCGGCCGCGCGGCGCACTACTGA

Upstream 100 bases:

>100_bases
ATGTGCGCGGCTTCGAGATCGACCGCGCGCATGCGCTGACCGGCCGCGACTGGGCCCAGCGGTCCGATCACGTGCCCCTG
CTGGCGGAACTGTCGCGCTC

Downstream 100 bases:

>100_bases
CGCAAGGCGGGCGCCTGCAATCACACGGAGGGGACATGCAGGTCATCACGGCGGAGGAAGCGGCGCGGCTGGTGCAGCCG
GGCTGGACGGTGGCGTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKVARDAGPLRSEWRRGKPLPGNRIDLLHGGAAFFPALIEAIDAARRRIALETYIYIDDDTGRRVTEALARAARRGVDVR
VTVDGFGTGTLPAGIAAMLDAAGAAWRVYRPVRGFRLQRRYLRRLHRKVAVIDDEVAFVGGINIIDDLNHTPFRDDALGA
RYDFAVRVRGPLVGQIALMVDRLWWQTGLLAGVREVGVTGVAAEFPVMTDTPKPGRRGASGTQHDQAPDNVLASLVLRDN
VRNRRAIEREYLRALGTARHEVIIANAYFLPGVRFMRALAACRRRGVRVRMLLQGHVEYAVQHYATRSLYHMLLRDGVEI
HEYTASFLHAKVAVVDGRWATVGSSNIDPFSLLLAREANVVAWDAGVAGQLRAALEDAIARHARPILADAHAARPWWWRV
VDWCAYRLVRLGVVISGRAAHY

Sequences:

>Translated_422_residues
MKVARDAGPLRSEWRRGKPLPGNRIDLLHGGAAFFPALIEAIDAARRRIALETYIYIDDDTGRRVTEALARAARRGVDVR
VTVDGFGTGTLPAGIAAMLDAAGAAWRVYRPVRGFRLQRRYLRRLHRKVAVIDDEVAFVGGINIIDDLNHTPFRDDALGA
RYDFAVRVRGPLVGQIALMVDRLWWQTGLLAGVREVGVTGVAAEFPVMTDTPKPGRRGASGTQHDQAPDNVLASLVLRDN
VRNRRAIEREYLRALGTARHEVIIANAYFLPGVRFMRALAACRRRGVRVRMLLQGHVEYAVQHYATRSLYHMLLRDGVEI
HEYTASFLHAKVAVVDGRWATVGSSNIDPFSLLLAREANVVAWDAGVAGQLRAALEDAIARHARPILADAHAARPWWWRV
VDWCAYRLVRLGVVISGRAAHY
>Mature_422_residues
MKVARDAGPLRSEWRRGKPLPGNRIDLLHGGAAFFPALIEAIDAARRRIALETYIYIDDDTGRRVTEALARAARRGVDVR
VTVDGFGTGTLPAGIAAMLDAAGAAWRVYRPVRGFRLQRRYLRRLHRKVAVIDDEVAFVGGINIIDDLNHTPFRDDALGA
RYDFAVRVRGPLVGQIALMVDRLWWQTGLLAGVREVGVTGVAAEFPVMTDTPKPGRRGASGTQHDQAPDNVLASLVLRDN
VRNRRAIEREYLRALGTARHEVIIANAYFLPGVRFMRALAACRRRGVRVRMLLQGHVEYAVQHYATRSLYHMLLRDGVEI
HEYTASFLHAKVAVVDGRWATVGSSNIDPFSLLLAREANVVAWDAGVAGQLRAALEDAIARHARPILADAHAARPWWWRV
VDWCAYRLVRLGVVISGRAAHY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=404, Percent_Identity=37.1287128712871, Blast_Score=234, Evalue=8e-63,
Organism=Escherichia coli, GI1787502, Length=396, Percent_Identity=27.5252525252525, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 46970; Mature: 46970

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVARDAGPLRSEWRRGKPLPGNRIDLLHGGAAFFPALIEAIDAARRRIALETYIYIDDD
CCCCCCCCCCHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEEEECC
TGRRVTEALARAARRGVDVRVTVDGFGTGTLPAGIAAMLDAAGAAWRVYRPVRGFRLQRR
CCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YLRRLHRKVAVIDDEVAFVGGINIIDDLNHTPFRDDALGARYDFAVRVRGPLVGQIALMV
HHHHHHHHHHHCCCCCCEECCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHH
DRLWWQTGLLAGVREVGVTGVAAEFPVMTDTPKPGRRGASGTQHDQAPDNVLASLVLRDN
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
VRNRRAIEREYLRALGTARHEVIIANAYFLPGVRFMRALAACRRRGVRVRMLLQGHVEYA
CHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCHHHHHHHHHHHHCCCEEEEHHHHHHHHH
VQHYATRSLYHMLLRDGVEIHEYTASFLHAKVAVVDGRWATVGSSNIDPFSLLLAREANV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCEEECCCCCCCHHHHHEECCCCE
VAWDAGVAGQLRAALEDAIARHARPILADAHAARPWWWRVVDWCAYRLVRLGVVISGRAA
EEECCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCC
HY
CC
>Mature Secondary Structure
MKVARDAGPLRSEWRRGKPLPGNRIDLLHGGAAFFPALIEAIDAARRRIALETYIYIDDD
CCCCCCCCCCHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEEEECC
TGRRVTEALARAARRGVDVRVTVDGFGTGTLPAGIAAMLDAAGAAWRVYRPVRGFRLQRR
CCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
YLRRLHRKVAVIDDEVAFVGGINIIDDLNHTPFRDDALGARYDFAVRVRGPLVGQIALMV
HHHHHHHHHHHCCCCCCEECCCHHHHCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHH
DRLWWQTGLLAGVREVGVTGVAAEFPVMTDTPKPGRRGASGTQHDQAPDNVLASLVLRDN
HHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
VRNRRAIEREYLRALGTARHEVIIANAYFLPGVRFMRALAACRRRGVRVRMLLQGHVEYA
CHHHHHHHHHHHHHHCCCCCEEEEEECHHHCCHHHHHHHHHHHHCCCEEEEHHHHHHHHH
VQHYATRSLYHMLLRDGVEIHEYTASFLHAKVAVVDGRWATVGSSNIDPFSLLLAREANV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEECCCEEECCCCCCCHHHHHEECCCCE
VAWDAGVAGQLRAALEDAIARHARPILADAHAARPWWWRVVDWCAYRLVRLGVVISGRAA
EEECCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCC
HY
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]