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The map label for this gene is aspC [H]

Identifier: 17228534

GI number: 17228534

Start: 1209924

End: 1211120

Strand: Direct

Name: aspC [H]

Synonym: alr1039

Alternate gene names: 17228534

Gene position: 1209924-1211120 (Clockwise)

Preceding gene: 17228533

Following gene: 17228535

Centisome position: 18.86

GC content: 41.19

Gene sequence:

>1197_bases
ATGACTAACTTCACTTCTCGGATGCAGGCGGTACAATCACCGATTATTCCTGTAGTTGGGGAATTAATTCAAAATTCACC
TGGGACTATTTCTTTGGGACAGGGTGTGGTTTCTTATAGTCCGCCACCAGAAGCTATTGAGCTTTTGCCGAGATTTTTGG
CTGACCCTGCTAATAATTTATATAAAGCTGTGGAGGGTATTCCTCCTTTGTTGAATGCGCTGACAGAAAAATTGTCTACA
TTCAACAACATTGAAATCACGACAGATAACTGTATTGTGGTGACGGCGGGAAGCAATATGGCGTTTATGAACGCTATTTT
GGCGATTACTTCTCCTGGTGATGAGATTATTCTGAATACGCCTTACTACTTCAACCACGAGATGGCGATCACCATGGCTG
GTTGTCGTGCAGTGTTGGTAGAAACCGATGAAAATTACCAACTGTGTCCAGAGGCGATCGCTCAAGCTATTACCCCAAAA
ACTCGCGCGGTGGTCACAATTTCCCCCAATAATCCTACAGGTGTTGTCTATTGCGAAGATTTGTTACGTAATGTAAATCA
AATTTGCGCTAATTATGGCATCTATCACATTAGTGATGAGGCTTATGAATACTTTACTTACGATGGTGTAAAACACGTTT
CTCCAGCCTCATTTGCAGGGAGTAGTGAGTATACAATTTCCCTTTATAGTCTTTCTAAAGCTTATGGGTTTGCCAGTTGG
CGAATTGGTTATATGGTAATTCCCAAACATCTGCTTGTCGCCATTAAAAAAGTCCAAGACACAATTTTGATTTGTCCGCC
TGTGGTTTCTCAGTATGCAGCTTTGGGAGCATTACAAGCAAAACCAGAGTATTTACAGGATCATATTGGAGCGTTGGCGC
AGCCTGCCGTAGGCATCGCTCAAGTCAGACAAATAGTATTCGACTACCTCAAGCAACTGCAAGGCTTATGTAATATTACT
CCCGCCGATGGTGCTTTCTATGTTTTTCTAAAAGTGCATACTCAGATAGATGCTTTTGCATTAGTCAAACAACTAATTCA
AGAATATAAAGTGGCTGTAATTCCGGGGACAACTTTTGGCATGGAAAATGGTTGTTATCTGCGGGTTGCTTACGGTGCTT
TGCAAAAAGATACAGTCAAAGAAGGTATTGAAAGGTTAGTACAAGGATTGAAAACAATTTTAGATACAGGAAAATGA

Upstream 100 bases:

>100_bases
AAGCTTGTCAACAGTGGCTTCAAGGACACAAACGCCATAAACAGATCGTCTCTCTGTTCAAATATATTAAAAGTTAGATA
TTAAGCAATACCTATGGCTG

Downstream 100 bases:

>100_bases
GATAATAATTTTCATAATCCATCATTCAGAAGTCAGAATCAATAAGACTTTGATATTACAGCTTAGTGCTTTGAATAAAA
TTAAAGCTATTATGATTGAT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPRFLADPANNLYKAVEGIPPLLNALTEKLST
FNNIEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNTPYYFNHEMAITMAGCRAVLVETDENYQLCPEAIAQAITPK
TRAVVTISPNNPTGVVYCEDLLRNVNQICANYGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIGALAQPAVGIAQVRQIVFDYLKQLQGLCNIT
PADGAFYVFLKVHTQIDAFALVKQLIQEYKVAVIPGTTFGMENGCYLRVAYGALQKDTVKEGIERLVQGLKTILDTGK

Sequences:

>Translated_398_residues
MTNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPRFLADPANNLYKAVEGIPPLLNALTEKLST
FNNIEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNTPYYFNHEMAITMAGCRAVLVETDENYQLCPEAIAQAITPK
TRAVVTISPNNPTGVVYCEDLLRNVNQICANYGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIGALAQPAVGIAQVRQIVFDYLKQLQGLCNIT
PADGAFYVFLKVHTQIDAFALVKQLIQEYKVAVIPGTTFGMENGCYLRVAYGALQKDTVKEGIERLVQGLKTILDTGK
>Mature_397_residues
TNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPRFLADPANNLYKAVEGIPPLLNALTEKLSTF
NNIEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNTPYYFNHEMAITMAGCRAVLVETDENYQLCPEAIAQAITPKT
RAVVTISPNNPTGVVYCEDLLRNVNQICANYGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASWR
IGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIGALAQPAVGIAQVRQIVFDYLKQLQGLCNITP
ADGAFYVFLKVHTQIDAFALVKQLIQEYKVAVIPGTTFGMENGCYLRVAYGALQKDTVKEGIERLVQGLKTILDTGK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=26.6497461928934, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI56713254, Length=392, Percent_Identity=26.7857142857143, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI95147551, Length=251, Percent_Identity=31.0756972111554, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI169881279, Length=251, Percent_Identity=31.0756972111554, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI169881281, Length=164, Percent_Identity=31.0975609756098, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI1786816, Length=366, Percent_Identity=27.0491803278689, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788722, Length=374, Percent_Identity=26.4705882352941, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788627, Length=378, Percent_Identity=25.6613756613757, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=26.530612244898, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=26.530612244898, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17567369, Length=430, Percent_Identity=23.7209302325581, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17567663, Length=325, Percent_Identity=23.6923076923077, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=402, Percent_Identity=28.3582089552239, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323118, Length=360, Percent_Identity=25.2777777777778, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320317, Length=383, Percent_Identity=24.0208877284595, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573069, Length=254, Percent_Identity=26.3779527559055, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24646114, Length=254, Percent_Identity=26.3779527559055, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573067, Length=254, Percent_Identity=26.3779527559055, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573065, Length=254, Percent_Identity=26.3779527559055, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI18859735, Length=300, Percent_Identity=25.6666666666667, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43419; Mature: 43287

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPRFLADPANNL
CCCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHH
YKAVEGIPPLLNALTEKLSTFNNIEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNT
HHHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEECCCCHHHHHEEEEEECCCCEEEECC
PYYFNHEMAITMAGCRAVLVETDENYQLCPEAIAQAITPKTRAVVTISPNNPTGVVYCED
CEEECCEEEEEEECCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEHHH
LLRNVNQICANYGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
HHHHHHHHHHHCCEEEECCCHHHEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHCCHHE
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIGALAQPAVGIA
EEEEEEHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
QVRQIVFDYLKQLQGLCNITPADGAFYVFLKVHTQIDAFALVKQLIQEYKVAVIPGTTFG
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHCCEEEECCCCCC
MENGCYLRVAYGALQKDTVKEGIERLVQGLKTILDTGK
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNFTSRMQAVQSPIIPVVGELIQNSPGTISLGQGVVSYSPPPEAIELLPRFLADPANNL
CCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHH
YKAVEGIPPLLNALTEKLSTFNNIEITTDNCIVVTAGSNMAFMNAILAITSPGDEIILNT
HHHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEECCCCHHHHHEEEEEECCCCEEEECC
PYYFNHEMAITMAGCRAVLVETDENYQLCPEAIAQAITPKTRAVVTISPNNPTGVVYCED
CEEECCEEEEEEECCEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCEEEEHHH
LLRNVNQICANYGIYHISDEAYEYFTYDGVKHVSPASFAGSSEYTISLYSLSKAYGFASW
HHHHHHHHHHHCCEEEECCCHHHEEEECCCCCCCCCCCCCCCCEEEEEEEHHHHHCCHHE
RIGYMVIPKHLLVAIKKVQDTILICPPVVSQYAALGALQAKPEYLQDHIGALAQPAVGIA
EEEEEEHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHH
QVRQIVFDYLKQLQGLCNITPADGAFYVFLKVHTQIDAFALVKQLIQEYKVAVIPGTTFG
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHCCEEEECCCCCC
MENGCYLRVAYGALQKDTVKEGIERLVQGLKTILDTGK
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]