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The map label for this gene is ffh

Identifier: 170762113

GI number: 170762113

Start: 111242

End: 112588

Strand: Direct

Name: ffh

Synonym: UPA3_0092

Alternate gene names: 170762113

Gene position: 111242-112588 (Clockwise)

Preceding gene: 170761892

Following gene: 170761999

Centisome position: 14.8

GC content: 30.36

Gene sequence:

>1347_bases
ATGTTCAAAGCAATGATAGGTAGTATTGTAAGTAAACAAATGTCAAAAAAATTAAAAAATGCGACAATTGTTGAAGAAGA
TATTAAAGAATTATTAAGCGAGATAAGAATAGCATTATTAGATGCTGACGTTAATTTATTAGTTGTTAAAAAATTTATTA
AAAACATCAAAGAAAAAACAATTGGATTGTATGTTGAAGCAAACCAAAAGCCAGCAGATCTTGTTTTAAAAATAATTAAA
GATGAATTAGTTGAAATTTTAGGAAAAGAAAATAAGCCAGTTAACACAGCTAAATCACAATTAAAAATTATGATGGTTGG
TTTACAAGGTTCAGGTAAAACAACAACTACTGGTAAATTAGCTAATTATTTTAAAAATAAATACAATAAAAAACCATTAT
TAGTGGCGGCTGATATCTATCGTCCAGCGGCGATTGATCAATTAAGAACATTAGCAAAACAAGTTCGTGTAGATTTTTGA
GAAGAAGGAACACAACGCCCTGATTTAATTGTAAAAAATGCTTTAAACAAAGCTGATGAAAATGAAAATAATTTGATAAT
TGTTGATACAGCTGGACGTTTACAAACAAACGAAGAGTTAATGCAAGAATTAGTAAATGTTAAAAAAACACTAAATCCTG
ATGAGGTTTTTTTAGTTGTTGATGCTATGGCAGGCCAAGACATTATTAACGTTGCTACAGAATTCAATAATTGATTAAAA
TTAACAGGTATTATTGTTACTAAATTAGATTCAGATGCACGTGCTGGAGCTGTTTTATCATTAACATCGTTATTAAATAT
ACCAATTAAATTCACAGGTACTGGTGAAAAAATAGGATCAATTGATAGTTTCTATCCAGAACGAATGGCTGATCGAATTT
TAGGTCTTGGTGATATCATGACTTTAGCAGAGAAAGCAGCTGATGTTATTGATGAAAAACAAGTTCGTGGTTCGATGCAA
CGAATGATGGCAGGAAAAATGGATTTAGAAGATTTAATGCGTCAAATGAGTCAAATTAGTAAATTAGGTAGTTTTTCAGG
AATAGCTAAGATGATTCCTGGATTGAACAATATTTCTGAAAACCAAATTGGTGATGCTGAGAGCAAAATGAAAATATGAA
CAATTTTATTATCAAGTATGACTTTAAAAGAACGTCGTGATCCGCGCGTTTTTAAAAAAGAACCATCAAGACGCATACGG
GTTTTAAAAGGATCAGGACGTTCGCCTGATGAATTAAATAAGTTATTAAAACAGTGGGAAGTGTCACGTGATAAAATGGC
AGAACTTGGTAAAATGTTACAAAAAGGAAAAAATCCTTTTAGTAAATCTGGTGGGTTATTTAGTTAA

Upstream 100 bases:

>100_bases
GTTTTTTATAATTTTATAAATTTCTTATTAAGAAATACAAAGATTAAATAATATAATTAATGATTAGTACAATAATTTTT
AAAATATAAAGAGGTAATTG

Downstream 100 bases:

>100_bases
AAATGGTTATACACCATTTTTTTATTTTATTTAATATAATAAATTGTTGAATAAGAAAAAATAAAACACTATCTTAATAA
TTTTTCTTATTATTCCATAT

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MFKAMIGSIVSKQMSKKLKNATIVEEDIKELLSEIRIALLDADVNLLVVKKFIKNIKEKTIGLYVEANQKPADLVLKIIK
DELVEILGKENKPVNTAKSQLKIMMVGLQGSGKTTTTGKLANYFKNKYNKKPLLVAADIYRPAAIDQLRTLAKQVRVDFW
EEGTQRPDLIVKNALNKADENENNLIIVDTAGRLQTNEELMQELVNVKKTLNPDEVFLVVDAMAGQDIINVATEFNNWLK
LTGIIVTKLDSDARAGAVLSLTSLLNIPIKFTGTGEKIGSIDSFYPERMADRILGLGDIMTLAEKAADVIDEKQVRGSMQ
RMMAGKMDLEDLMRQMSQISKLGSFSGIAKMIPGLNNISENQIGDAESKMKIWTILLSSMTLKERRDPRVFKKEPSRRIR
VLKGSGRSPDELNKLLKQWEVSRDKMAELGKMLQKGKNPFSKSGGLFS

Sequences:

>Translated_448_residues
MFKAMIGSIVSKQMSKKLKNATIVEEDIKELLSEIRIALLDADVNLLVVKKFIKNIKEKTIGLYVEANQKPADLVLKIIK
DELVEILGKENKPVNTAKSQLKIMMVGLQGSGKTTTTGKLANYFKNKYNKKPLLVAADIYRPAAIDQLRTLAKQVRVDF*
EEGTQRPDLIVKNALNKADENENNLIIVDTAGRLQTNEELMQELVNVKKTLNPDEVFLVVDAMAGQDIINVATEFNN*LK
LTGIIVTKLDSDARAGAVLSLTSLLNIPIKFTGTGEKIGSIDSFYPERMADRILGLGDIMTLAEKAADVIDEKQVRGSMQ
RMMAGKMDLEDLMRQMSQISKLGSFSGIAKMIPGLNNISENQIGDAESKMKI*TILLSSMTLKERRDPRVFKKEPSRRIR
VLKGSGRSPDELNKLLKQWEVSRDKMAELGKMLQKGKNPFSKSGGLFS
>Mature_448_residues
MFKAMIGSIVSKQMSKKLKNATIVEEDIKELLSEIRIALLDADVNLLVVKKFIKNIKEKTIGLYVEANQKPADLVLKIIK
DELVEILGKENKPVNTAKSQLKIMMVGLQGSGKTTTTGKLANYFKNKYNKKPLLVAADIYRPAAIDQLRTLAKQVRVDF*
EEGTQRPDLIVKNALNKADENENNLIIVDTAGRLQTNEELMQELVNVKKTLNPDEVFLVVDAMAGQDIINVATEFNN*LK
LTGIIVTKLDSDARAGAVLSLTSLLNIPIKFTGTGEKIGSIDSFYPERMADRILGLGDIMTLAEKAADVIDEKQVRGSMQ
RMMAGKMDLEDLMRQMSQISKLGSFSGIAKMIPGLNNISENQIGDAESKMKI*TILLSSMTLKERRDPRVFKKEPSRRIR
VLKGSGRSPDELNKLLKQWEVSRDKMAELGKMLQKGKNPFSKSGGLFS

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=413, Percent_Identity=33.1719128329298, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI226371618, Length=324, Percent_Identity=34.5679012345679, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI295424842, Length=318, Percent_Identity=24.2138364779874, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI23308697, Length=318, Percent_Identity=24.2138364779874, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI89061728, Length=140, Percent_Identity=36.4285714285714, Blast_Score=86, Evalue=8e-17,
Organism=Escherichia coli, GI1788963, Length=419, Percent_Identity=40.3341288782816, Blast_Score=313, Evalue=1e-86,
Organism=Escherichia coli, GI1789874, Length=251, Percent_Identity=35.4581673306773, Blast_Score=134, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17539958, Length=439, Percent_Identity=33.2574031890661, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI193206261, Length=279, Percent_Identity=28.673835125448, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325345, Length=418, Percent_Identity=36.3636363636364, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320498, Length=304, Percent_Identity=26.6447368421053, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647949, Length=413, Percent_Identity=31.4769975786925, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24641198, Length=200, Percent_Identity=31, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49401; Mature: 49401

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50191 CRAL_TRIO ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKAMIGSIVSKQMSKKLKNATIVEEDIKELLSEIRIALLDADVNLLVVKKFIKNIKEKT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IGLYVEANQKPADLVLKIIKDELVEILGKENKPVNTAKSQLKIMMVGLQGSGKTTTTGKL
EEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCEEEEEEEECCCCCCCCHHHH
ANYFKNKYNKKPLLVAADIYRPAAIDQLRTLAKQVRVDFEEGTQRPDLIVKNALNKADEN
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCC
ENNLIIVDTAGRLQTNEELMQELVNVKKTLNPDEVFLVVDAMAGQDIINVATEFNNLKLT
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCEEEE
GIIVTKLDSDARAGAVLSLTSLLNIPIKFTGTGEKIGSIDSFYPERMADRILGLGDIMTL
EEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHCCHHHHHHHHHHHHHHCHHHHHHH
AEKAADVIDEKQVRGSMQRMMAGKMDLEDLMRQMSQISKLGSFSGIAKMIPGLNNISENQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC
IGDAESKMKITILLSSMTLKERRDPRVFKKEPSRRIRVLKGSGRSPDELNKLLKQWEVSR
CCCCCCCEEEEEEEEHHHHHHCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
DKMAELGKMLQKGKNPFSKSGGLFS
HHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MFKAMIGSIVSKQMSKKLKNATIVEEDIKELLSEIRIALLDADVNLLVVKKFIKNIKEKT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IGLYVEANQKPADLVLKIIKDELVEILGKENKPVNTAKSQLKIMMVGLQGSGKTTTTGKL
EEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCEEEEEEEECCCCCCCCHHHH
ANYFKNKYNKKPLLVAADIYRPAAIDQLRTLAKQVRVDFEEGTQRPDLIVKNALNKADEN
HHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCC
ENNLIIVDTAGRLQTNEELMQELVNVKKTLNPDEVFLVVDAMAGQDIINVATEFNNLKLT
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHCCCEEEE
GIIVTKLDSDARAGAVLSLTSLLNIPIKFTGTGEKIGSIDSFYPERMADRILGLGDIMTL
EEEEEEECCCCCCCHHHHHHHHHCCCEEEECCCCHHCCHHHHHHHHHHHHHHCHHHHHHH
AEKAADVIDEKQVRGSMQRMMAGKMDLEDLMRQMSQISKLGSFSGIAKMIPGLNNISENQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCC
IGDAESKMKITILLSSMTLKERRDPRVFKKEPSRRIRVLKGSGRSPDELNKLLKQWEVSR
CCCCCCCEEEEEEEEHHHHHHCCCCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCH
DKMAELGKMLQKGKNPFSKSGGLFS
HHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]