Click here to switch to the map view.

The map label for this gene is ptsG [H]

Identifier: 170755203

GI number: 170755203

Start: 358518

End: 359027

Strand: Direct

Name: ptsG [H]

Synonym: CLD_0472

Alternate gene names: 170755203

Gene position: 358518-359027 (Clockwise)

Preceding gene: 170754623

Following gene: 170755076

Centisome position: 9.06

GC content: 30.59

Gene sequence:

>510_bases
ATGTTTAAAAAAATTAAATCTCTTTTAACTAATGATCAATCAGATATTCAACAAGAAGATTTAAATGAAGTATTTGTAAG
TCCTATTTCTGGAGAAATAATAAGTCTAGATGATGTTCCAGATGAGGTATTTTCTCAAAGAATGATGGGAGATGGGTTTG
CTATACAGCCTGAAAATGGAGAGGTATTTTCACCAGTGGATGGAACAATTACAGCAGTTTTCCCTACCAAACATGCTATT
TCTATAAAAAGTGAATCTGGAGTTGAGATTTTGGTTCATTTTGGCTTAGATACAGTTAACTTAAATGGAGAAGGTTTTCA
GGTTTATGTTGAGGAAGGAAATCAAGTAAAAGCAGGAGATATGTTACTAAAGGTTAATATTGAAGAAATAAAGGATAAAG
TTCCTTCACTTATTGTTCCTATAATATTTATGGATCTTAATGGAAAGAGCTTTAGTTATAATACTGGTAAGGTTACAGCT
AAAGAGCCAAATATAATAACATTAAAGTAA

Upstream 100 bases:

>100_bases
AGAAAAATTATTGTAAAATTAGTTGAGACTGCCAAAAGTAGATTAAAATCTATTTTAGACAGTCTCTTTTGAAAATAAGG
TATACATAGGAGGAATTAAA

Downstream 100 bases:

>100_bases
TCTGCATATATACATATTTTAAAATTCTAATTATGATAATTATATATTTTAAGTTTATTAGTTCATGAAAATTTCTAACA
CATGTTCCTTTGTTATATTT

Product: PTS system, glucose/glucoside family, IIA component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MFKKIKSLLTNDQSDIQQEDLNEVFVSPISGEIISLDDVPDEVFSQRMMGDGFAIQPENGEVFSPVDGTITAVFPTKHAI
SIKSESGVEILVHFGLDTVNLNGEGFQVYVEEGNQVKAGDMLLKVNIEEIKDKVPSLIVPIIFMDLNGKSFSYNTGKVTA
KEPNIITLK

Sequences:

>Translated_169_residues
MFKKIKSLLTNDQSDIQQEDLNEVFVSPISGEIISLDDVPDEVFSQRMMGDGFAIQPENGEVFSPVDGTITAVFPTKHAI
SIKSESGVEILVHFGLDTVNLNGEGFQVYVEEGNQVKAGDMLLKVNIEEIKDKVPSLIVPIIFMDLNGKSFSYNTGKVTA
KEPNIITLK
>Mature_169_residues
MFKKIKSLLTNDQSDIQQEDLNEVFVSPISGEIISLDDVPDEVFSQRMMGDGFAIQPENGEVFSPVDGTITAVFPTKHAI
SIKSESGVEILVHFGLDTVNLNGEGFQVYVEEGNQVKAGDMLLKVNIEEIKDKVPSLIVPIIFMDLNGKSFSYNTGKVTA
KEPNIITLK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=170, Percent_Identity=41.1764705882353, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI1786894, Length=123, Percent_Identity=43.0894308943089, Blast_Score=119, Evalue=9e-29,
Organism=Escherichia coli, GI1790159, Length=141, Percent_Identity=41.1347517730496, Blast_Score=109, Evalue=8e-26,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR011535 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 18577; Mature: 18577

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKIKSLLTNDQSDIQQEDLNEVFVSPISGEIISLDDVPDEVFSQRMMGDGFAIQPENG
CHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCC
EVFSPVDGTITAVFPTKHAISIKSESGVEILVHFGLDTVNLNGEGFQVYVEEGNQVKAGD
CEECCCCCEEEEEECCCEEEEEECCCCEEEEEEECCEEEEECCCCEEEEEECCCEEECCC
MLLKVNIEEIKDKVPSLIVPIIFMDLNGKSFSYNTGKVTAKEPNIITLK
EEEEEEHHHHHHHCCCEEEEEEEEECCCCEEEECCCEEEECCCCEEEEC
>Mature Secondary Structure
MFKKIKSLLTNDQSDIQQEDLNEVFVSPISGEIISLDDVPDEVFSQRMMGDGFAIQPENG
CHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCC
EVFSPVDGTITAVFPTKHAISIKSESGVEILVHFGLDTVNLNGEGFQVYVEEGNQVKAGD
CEECCCCCEEEEEECCCEEEEEECCCCEEEEEEECCEEEEECCCCEEEEEECCCEEECCC
MLLKVNIEEIKDKVPSLIVPIIFMDLNGKSFSYNTGKVTAKEPNIITLK
EEEEEEHHHHHHHCCCEEEEEEEEECCCCEEEECCCEEEECCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7670643 [H]