Click here to switch to the map view.

The map label for this gene is appB [H]

Identifier: 170754630

GI number: 170754630

Start: 1360767

End: 1361720

Strand: Reverse

Name: appB [H]

Synonym: CLD_3342

Alternate gene names: 170754630

Gene position: 1361720-1360767 (Counterclockwise)

Preceding gene: 170755096

Following gene: 170757306

Centisome position: 34.4

GC content: 28.62

Gene sequence:

>954_bases
TTGAGTAAATACATAAGAAAACGAATTGTGGAAGCAATTCCCATACTTATTTTCATTTCTATAATTTCTTTTTTACTAAT
AAAATTAGCACCGGGAGATCCTATTAGAGCCTTTATAAATCCCAAAATGAAGCCTTCTGATATAGCTAGAATTAGGCATA
ATTTAGGTCTTGATAAACCTATATATATACAATATATCTTATGGTTAAAAAATGTATTAAAAGGTGATTTAGGTTATTCT
TTAATAAACTCTAGACCAATTTCTACACAAATAATAGAAAGACTTCCTGCTACCTTACTTCTTATAGGTTCCTCTTTATT
AATATCTTTAGTTTTAGGTATAATTTTGGGAGTTATTTCTGCAGTTAATAAAAATAAACTTATAGATAATATCCTTTCAG
TAATCTCTTATATAGGTATATCTATACCTAGTTTTTGGTTTGCTATGATACTAATATACATTTTTTCCGTTAACCTTAAA
TTGCTACCCAGTGTTGGTATGCATACTATAGGTGTAGATTCTAGATTAGATGTATTAAAACATCTTATTTTACCTTGCAC
AGTATTAAGTTTTGGAAACATATCAGTTATTACTAGATATATAAGATCCAATGTAATCTCTGAACTGTCTGAAGATTATG
TTATGATTGCCTATGCCAAAGGATTATCTAAAAAAAGAATATTATATAAACATGTTTTAAAGAATGCCCTTTTGCCTATT
ATCACCATATTAGGCATGTCCTTACCTAATTTAGTAGCTGGTGCTTTTATAACTGAAACTATTTTTGGATGGCCTGGTAT
GGGTAGACTAGGTATAAAAGCTATATTTGGTTTTGACTATCCTCTTATTATGGCTATAACTATGTTAACTTCTGTTTTAC
TTATAATAGGTAACCTTTTAGCAGACATATGTTATAGCTTAATAGATCCTAGAATTAAAGAGTTAGGTAGGTGA

Upstream 100 bases:

>100_bases
TATTTTTTATTTAATATATCAAAGCACTAAAATTTAGCTAACAATTATTATTTAATCTTTAAATTATATAATAAAAATAA
TTAAGAAAGGTAGGATATAT

Downstream 100 bases:

>100_bases
TAAATTTGTTCTTAAATGAAAGACTTAAACTAAATTTAAAAATACAATTTAAAGAAAATAAATTAGGATATATTTCCTTA
TCTATAATATTGATATTAAT

Product: putative oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPKMKPSDIARIRHNLGLDKPIYIQYILWLKNVLKGDLGYS
LINSRPISTQIIERLPATLLLIGSSLLISLVLGIILGVISAVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLK
LLPSVGMHTIGVDSRLDVLKHLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLLADICYSLIDPRIKELGR

Sequences:

>Translated_317_residues
MSKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPKMKPSDIARIRHNLGLDKPIYIQYILWLKNVLKGDLGYS
LINSRPISTQIIERLPATLLLIGSSLLISLVLGIILGVISAVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLK
LLPSVGMHTIGVDSRLDVLKHLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLLADICYSLIDPRIKELGR
>Mature_316_residues
SKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPKMKPSDIARIRHNLGLDKPIYIQYILWLKNVLKGDLGYSL
INSRPISTQIIERLPATLLLIGSSLLISLVLGIILGVISAVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLKL
LPSVGMHTIGVDSRLDVLKHLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPII
TILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLLADICYSLIDPRIKELGR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=313, Percent_Identity=36.4217252396166, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1789888, Length=317, Percent_Identity=35.0157728706625, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1789965, Length=337, Percent_Identity=34.1246290801187, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=35.5421686746988, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI1787497, Length=314, Percent_Identity=33.4394904458599, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=32.3529411764706, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788504, Length=364, Percent_Identity=29.6703296703297, Blast_Score=149, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35239; Mature: 35108

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPKMKPSDIARIRHNLGLDKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCH
IYIQYILWLKNVLKGDLGYSLINSRPISTQIIERLPATLLLIGSSLLISLVLGIILGVIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLKLLPSVGMHTIGVDSRLDVLK
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHHHHHH
HLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHH
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ADICYSLIDPRIKELGR
HHHHHHHHCHHHHHHCC
>Mature Secondary Structure 
SKYIRKRIVEAIPILIFISIISFLLIKLAPGDPIRAFINPKMKPSDIARIRHNLGLDKP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCH
IYIQYILWLKNVLKGDLGYSLINSRPISTQIIERLPATLLLIGSSLLISLVLGIILGVIS
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVNKNKLIDNILSVISYIGISIPSFWFAMILIYIFSVNLKLLPSVGMHTIGVDSRLDVLK
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCCHHCCCCHHHHHHH
HLILPCTVLSFGNISVITRYIRSNVISELSEDYVMIAYAKGLSKKRILYKHVLKNALLPI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHH
ITILGMSLPNLVAGAFITETIFGWPGMGRLGIKAIFGFDYPLIMAITMLTSVLLIIGNLL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ADICYSLIDPRIKELGR
HHHHHHHHCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]