Click here to switch to the map view.

The map label for this gene is clpX [H]

Identifier: 170751515

GI number: 170751515

Start: 5458277

End: 5459548

Strand: Direct

Name: clpX [H]

Synonym: Mrad2831_5135

Alternate gene names: 170751515

Gene position: 5458277-5459548 (Clockwise)

Preceding gene: 170751514

Following gene: 170751516

Centisome position: 89.81

GC content: 66.59

Gene sequence:

>1272_bases
ATGAGCAAGACTGGCGGCAACGACTCGAAGAGCACGCTGTATTGCTCGTTCTGCGGCAAGAGCCAGCACGAGGTCCGCAA
GCTGATCGCCGGCCCCACGGTGTTCATCTGCGACGAGTGCGTCGAGCTGTGCATGGACATCATCCGCGAGGAGTCGAAAT
CCTCGCTGGTGAAGAGCCGCGACGGCGTGCCGACCCCCAAGGAGATCCGCCGCGTCCTCGACGACTACGTCATCGGCCAG
GACTTCGCCAAGAAGGTCCTCTCGGTCGCGGTGCACAACCACTACAAGCGGCTCGCCCACGCGACGAAGCACAACGACGT
CGAGCTGGCCAAGTCCAACATCATGCTGATCGGGCCGACCGGCTCGGGCAAGACCCTGCTCGCGCAGACGCTCGCCCGCA
TCCTGGACGTGCCGTTCACCATGGCGGACGCCACGACGCTGACCGAGGCCGGCTACGTCGGTGAGGACGTCGAGAACATC
ATCCTCAAGCTGCTCCAGGCCTCGGACTACAACGTCGAGCGGGCGCAGCGCGGCATCGTCTACATCGACGAGATCGACAA
GATCTCCCGCAAGTCCGACAACCCGTCGATCACCCGCGACGTGTCGGGCGAGGGCGTGCAGCAGGCGCTCCTGAAGATCA
TGGAGGGTACGGTCGCCTCCGTCCCGCCCCAGGGCGGACGGAAGCACCCGCAGCAGGAATTCCTGCAGGTCGACACGACC
AACATCCTGTTCATCTGCGGCGGCGCCTTCGCGGGGCTGGAGCGGATCATCTCCCAGCGCGGCAAGGGTACCTCGATCGG
CTTCGGCGCGACCGTCCAGGCCCCGGACGACCGCCGCACCGGCGAGATCTTCCGCTCGGTCGAGCCGGAGGACCTGCTGA
AGTTCGGCCTCATCCCCGAGTTCGTCGGCCGCCTGCCGGTCCTGGCGACGCTGGAGGACCTCGACGAGGCCGCGCTGAAG
AAGATCCTGCAGGAGCCGAAGAACGCCCTGGTGAAGCAGTACCAGCGGCTGTTCGAGATGGAGAACGTCGACCTGACCTT
CCAGGACGAGGCCCTGTCGCTCGTCGCCCGCAAGGCGATCGAGCGGAAGACCGGCGCCCGCGGCCTGCGCTCCATCCTGG
AGACGATCCTGCTGGACACGATGTACGACCTGCCGGGCCTCGAGTCCGTGGAGCAGGTGGTCATCGGCCCGGAGGTGGTC
GAGGGCAAGTCGCGCCCCCTCTACATCCACGGCGACCGCAACAAGGACGCGCCCGCCAGCGTCAGCGCGTAG

Upstream 100 bases:

>100_bases
AAAGGCGCGCAGCACACTGTTTCTTTAAACGGGCCCCCTACATTCATGCGATGCGCGTCCGCCCCTTGCCGGCTGCGGAC
GCGAGGAATCGGAGACCGAT

Downstream 100 bases:

>100_bases
GCGCTCGGTAGGGTTGCATGAGGCGCCCGGCTCTGGCCGGGCGCGCTGCGGAGGCCGCCTTGAAAACGCTCCCCCCCGCA
GCCACCTCAGGCTCAGCGCG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQ
DFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLERIISQRGKGTSIGFGATVQAPDDRRTGEIFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEAALK
KILQEPKNALVKQYQRLFEMENVDLTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVV
EGKSRPLYIHGDRNKDAPASVSA

Sequences:

>Translated_423_residues
MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQ
DFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENI
ILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
NILFICGGAFAGLERIISQRGKGTSIGFGATVQAPDDRRTGEIFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEAALK
KILQEPKNALVKQYQRLFEMENVDLTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVV
EGKSRPLYIHGDRNKDAPASVSA
>Mature_422_residues
SKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQD
FAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENII
LKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTN
ILFICGGAFAGLERIISQRGKGTSIGFGATVQAPDDRRTGEIFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEAALKK
ILQEPKNALVKQYQRLFEMENVDLTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVE
GKSRPLYIHGDRNKDAPASVSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=52.710843373494, Blast_Score=327, Evalue=2e-89,
Organism=Escherichia coli, GI1786642, Length=414, Percent_Identity=72.7053140096618, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=43.3962264150943, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=319, Percent_Identity=46.7084639498433, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=319, Percent_Identity=46.7084639498433, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=391, Percent_Identity=38.618925831202, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=418, Percent_Identity=38.2775119617225, Blast_Score=263, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24648291, Length=332, Percent_Identity=49.0963855421687, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI24648289, Length=332, Percent_Identity=49.0963855421687, Blast_Score=307, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46479; Mature: 46348

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPT
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLERIISQRGKGTSIGFGATVQAPDDRRTGEIFRSVEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHCCCHHHHHHHCCCHH
FVGRLPVLATLEDLDEAALKKILQEPKNALVKQYQRLFEMENVDLTFQDEALSLVARKAI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
ERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVEGKSRPLYIHGDRNKDAPAS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCCCC
VSA
CCC
>Mature Secondary Structure 
SKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSR
CCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPT
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEEEEECC
GSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIV
CCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCE
YIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTT
EEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLERIISQRGKGTSIGFGATVQAPDDRRTGEIFRSVEPEDLLKFGLIPE
CEEEEECCHHHHHHHHHHCCCCCCCCCCCCEECCCCCCHHHHHHHCCCHHHHHHHCCCHH
FVGRLPVLATLEDLDEAALKKILQEPKNALVKQYQRLFEMENVDLTFQDEALSLVARKAI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHH
ERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVEGKSRPLYIHGDRNKDAPAS
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHCCCCCCEEEECCCCCCCCCC
VSA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA