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The map label for this gene is glpD [H]

Identifier: 170748597

GI number: 170748597

Start: 2321005

End: 2322537

Strand: Reverse

Name: glpD [H]

Synonym: Mrad2831_2179

Alternate gene names: 170748597

Gene position: 2322537-2321005 (Counterclockwise)

Preceding gene: 170748598

Following gene: 170748596

Centisome position: 38.21

GC content: 72.02

Gene sequence:

>1533_bases
ATGGCGGCAGCACCGGGCCAGCGCGAGCCGTCCGACGCCTACGATCTCCTGATCATCGGCGGCGGCATCAACGGCACGGG
CATCGCCCGGGACGCGGCCGGCCGGGGCCTTTCGGTCCTGCTGGCCGAGCGCGGGGATCTGGCGGGCTTCACGTCCTCGT
CCTCGACGAAGCTGATCCACGGCGGCCTGCGTTACCTCGAATATTACGAGTTCCGCCTGGTGCGGGAGGCGCTCGCCGAG
CGCGAGCGGCTGCTGCGGCTCGCCCCGCACGTGATCTGGCCCCTGCGCTTCGTCCTGCCCCACGACGAGGGCCTGCGCCC
GGCCTGGATGCTGCGGCTGGGCCTGTTCCTGTACGATCACCTCGCGCGGCTGCGCACCCTCCCGGGCTCGCACGGGGTCG
ACCTGCGCAGCTCCGCCTACGGAGCGCCGCTGCAGCGGCGCCTGAAGCGCGGCTTCGTCTATTCCGACTGCTGGGTCGAG
GACAGCCGCCTCGTGGTGCTAAACGCCATGGACGCCCGCGAGCGCGGCGCGACGGTGCTGACCCGAACCGGCGTGGTCTC
GGCCCGGCGTGAGGGTGACGGCTGGGCCGCGACCTTGCGCGACGAGCGCGGCGGCACCGAGCGGACGATCCGCGCGACGG
CCGTCGTCAACGCCGCCGGCCCCTGGGTCAGCGAGACGCTCGGCGGCACGCTCGGCGTCAACAGCCGCGCGGCGGTGCGG
CTGATCAAGGGCAGCCACATCGTGGTCAAGCGCCTGTTCGACGGCGATCAGGCCTACATCCTGCAGCAGCCCGACAAGCG
CATCATCTTCGCGATCCCCTACGAGCGCGACTTCACGCTGATCGGCACCACGGACGTTCCCTACGAGGGCGAGCCCGGCC
CGGTCACGATCTCGGAGAGCGAGACCGACTATCTCTGCGGCTGCATCAACCGCTCCTTCGACACGACGCTCACCCCGGCC
GACGTGGTCTGGAGCTATGCGGGCGTGCGCCCGCTCTACGACGACGCGGCGGAGAACGCCTCGGCCGTGACCCGCGACTA
CGTCCTCGACGTGGAGGACCAGGGCGGGACTGCGGCGGTGCTGTCGGTCTTCGGCGGCAAGATCACGACCTACCGGCGGC
TCGCCGAGCACGCGCTCGAGAAGCTGAAGCCCTATTTCCCGCACCTCAAGAAGGCCTGGACCGGCGACGCGGTCCTGCCC
GGCGGCGCCATGAAGGACGCGGATTTCGACCGGTTCCTCGCCGAGCTGAGGGCCGAGAAGCCGTTCCTGCCGGAGGAGAC
CGCCCGCCGGCTCGCCCGCGCCTACGGAACCCGGGCCCGGGACATCGTCGGGACGGCGCGGTCCATGGCGGATCTCGGCG
AGGCCTTCGACGGCGGCCTCACCGCCGCCGAGGTCGATTACCTGCGCACCGAGGAATGGGCGGTCACCGCCGACGACATC
CTGTGGCGGCGGTCGAAGCTCGGCCTGCGCACCGGCGCGGAGAGCGCCGCGCGCCTCGCCGCCTACCTCGACCGCAGGGC
CGAGGCCGCCTGA

Upstream 100 bases:

>100_bases
CGCGGCCGAACCCTAACGAACATCGATTTTTTCGCTTGCGAAAGCCGAGGGCTGCGTCAATATACTGCCAATCCGCCAGC
AGGGCGGCTCCGGAGGAACC

Downstream 100 bases:

>100_bases
TGCTTTCGAACCCGATCCGGCGGCAGACCGGTCGGGCCTATGAAGGGAGGGAACGATGAGCCGTTACGTCGGGGCCATCG
ACCAGGGTACCACCAGCAGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MAAAPGQREPSDAYDLLIIGGGINGTGIARDAAGRGLSVLLAERGDLAGFTSSSSTKLIHGGLRYLEYYEFRLVREALAE
RERLLRLAPHVIWPLRFVLPHDEGLRPAWMLRLGLFLYDHLARLRTLPGSHGVDLRSSAYGAPLQRRLKRGFVYSDCWVE
DSRLVVLNAMDARERGATVLTRTGVVSARREGDGWAATLRDERGGTERTIRATAVVNAAGPWVSETLGGTLGVNSRAAVR
LIKGSHIVVKRLFDGDQAYILQQPDKRIIFAIPYERDFTLIGTTDVPYEGEPGPVTISESETDYLCGCINRSFDTTLTPA
DVVWSYAGVRPLYDDAAENASAVTRDYVLDVEDQGGTAAVLSVFGGKITTYRRLAEHALEKLKPYFPHLKKAWTGDAVLP
GGAMKDADFDRFLAELRAEKPFLPEETARRLARAYGTRARDIVGTARSMADLGEAFDGGLTAAEVDYLRTEEWAVTADDI
LWRRSKLGLRTGAESAARLAAYLDRRAEAA

Sequences:

>Translated_510_residues
MAAAPGQREPSDAYDLLIIGGGINGTGIARDAAGRGLSVLLAERGDLAGFTSSSSTKLIHGGLRYLEYYEFRLVREALAE
RERLLRLAPHVIWPLRFVLPHDEGLRPAWMLRLGLFLYDHLARLRTLPGSHGVDLRSSAYGAPLQRRLKRGFVYSDCWVE
DSRLVVLNAMDARERGATVLTRTGVVSARREGDGWAATLRDERGGTERTIRATAVVNAAGPWVSETLGGTLGVNSRAAVR
LIKGSHIVVKRLFDGDQAYILQQPDKRIIFAIPYERDFTLIGTTDVPYEGEPGPVTISESETDYLCGCINRSFDTTLTPA
DVVWSYAGVRPLYDDAAENASAVTRDYVLDVEDQGGTAAVLSVFGGKITTYRRLAEHALEKLKPYFPHLKKAWTGDAVLP
GGAMKDADFDRFLAELRAEKPFLPEETARRLARAYGTRARDIVGTARSMADLGEAFDGGLTAAEVDYLRTEEWAVTADDI
LWRRSKLGLRTGAESAARLAAYLDRRAEAA
>Mature_509_residues
AAAPGQREPSDAYDLLIIGGGINGTGIARDAAGRGLSVLLAERGDLAGFTSSSSTKLIHGGLRYLEYYEFRLVREALAER
ERLLRLAPHVIWPLRFVLPHDEGLRPAWMLRLGLFLYDHLARLRTLPGSHGVDLRSSAYGAPLQRRLKRGFVYSDCWVED
SRLVVLNAMDARERGATVLTRTGVVSARREGDGWAATLRDERGGTERTIRATAVVNAAGPWVSETLGGTLGVNSRAAVRL
IKGSHIVVKRLFDGDQAYILQQPDKRIIFAIPYERDFTLIGTTDVPYEGEPGPVTISESETDYLCGCINRSFDTTLTPAD
VVWSYAGVRPLYDDAAENASAVTRDYVLDVEDQGGTAAVLSVFGGKITTYRRLAEHALEKLKPYFPHLKKAWTGDAVLPG
GAMKDADFDRFLAELRAEKPFLPEETARRLARAYGTRARDIVGTARSMADLGEAFDGGLTAAEVDYLRTEEWAVTADDIL
WRRSKLGLRTGAESAARLAAYLDRRAEAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=549, Percent_Identity=29.3260473588342, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI285002231, Length=549, Percent_Identity=29.3260473588342, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI2367226, Length=467, Percent_Identity=51.8201284796574, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788574, Length=489, Percent_Identity=27.19836400818, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115534726, Length=514, Percent_Identity=29.3774319066148, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17509253, Length=508, Percent_Identity=30.511811023622, Blast_Score=160, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322036, Length=560, Percent_Identity=30, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161077125, Length=530, Percent_Identity=30.377358490566, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24653942, Length=530, Percent_Identity=30.377358490566, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24653944, Length=530, Percent_Identity=30.377358490566, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI20130025, Length=530, Percent_Identity=30.377358490566, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24586295, Length=507, Percent_Identity=28.0078895463511, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI19921278, Length=536, Percent_Identity=25, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56002; Mature: 55871

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAPGQREPSDAYDLLIIGGGINGTGIARDAAGRGLSVLLAERGDLAGFTSSSSTKLIH
CCCCCCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCCCCCCCCCCHHH
GGLRYLEYYEFRLVREALAERERLLRLAPHVIWPLRFVLPHDEGLRPAWMLRLGLFLYDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
LARLRTLPGSHGVDLRSSAYGAPLQRRLKRGFVYSDCWVEDSRLVVLNAMDARERGATVL
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECEECCCCEEEEEECCCCCCCCEEE
TRTGVVSARREGDGWAATLRDERGGTERTIRATAVVNAAGPWVSETLGGTLGVNSRAAVR
EECCCEEECCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHCCCCCCCCCCCEEE
LIKGSHIVVKRLFDGDQAYILQQPDKRIIFAIPYERDFTLIGTTDVPYEGEPGPVTISES
EECCCEEEEEEECCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEECCC
ETDYLCGCINRSFDTTLTPADVVWSYAGVRPLYDDAAENASAVTRDYVLDVEDQGGTAAV
CCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHCCHHHEEHEEEEEECCCCCHHHH
LSVFGGKITTYRRLAEHALEKLKPYFPHLKKAWTGDAVLPGGAMKDADFDRFLAELRAEK
HHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
PFLPEETARRLARAYGTRARDIVGTARSMADLGEAFDGGLTAAEVDYLRTEEWAVTADDI
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEHHHH
LWRRSKLGLRTGAESAARLAAYLDRRAEAA
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAAPGQREPSDAYDLLIIGGGINGTGIARDAAGRGLSVLLAERGDLAGFTSSSSTKLIH
CCCCCCCCCCCCEEEEEEECCCCCCCCCHHCCCCCEEEEEECCCCCCCCCCCCCCCHHH
GGLRYLEYYEFRLVREALAERERLLRLAPHVIWPLRFVLPHDEGLRPAWMLRLGLFLYDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
LARLRTLPGSHGVDLRSSAYGAPLQRRLKRGFVYSDCWVEDSRLVVLNAMDARERGATVL
HHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEECEECCCCEEEEEECCCCCCCCEEE
TRTGVVSARREGDGWAATLRDERGGTERTIRATAVVNAAGPWVSETLGGTLGVNSRAAVR
EECCCEEECCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCHHHHHCCCCCCCCCCCEEE
LIKGSHIVVKRLFDGDQAYILQQPDKRIIFAIPYERDFTLIGTTDVPYEGEPGPVTISES
EECCCEEEEEEECCCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCEEECCC
ETDYLCGCINRSFDTTLTPADVVWSYAGVRPLYDDAAENASAVTRDYVLDVEDQGGTAAV
CCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHCCHHHEEHEEEEEECCCCCHHHH
LSVFGGKITTYRRLAEHALEKLKPYFPHLKKAWTGDAVLPGGAMKDADFDRFLAELRAEK
HHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCC
PFLPEETARRLARAYGTRARDIVGTARSMADLGEAFDGGLTAAEVDYLRTEEWAVTADDI
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEEHHHH
LWRRSKLGLRTGAESAARLAAYLDRRAEAA
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]