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The map label for this gene is glpR [H]

Identifier: 170748598

GI number: 170748598

Start: 2322622

End: 2323443

Strand: Reverse

Name: glpR [H]

Synonym: Mrad2831_2180

Alternate gene names: 170748598

Gene position: 2323443-2322622 (Counterclockwise)

Preceding gene: 170748599

Following gene: 170748597

Centisome position: 38.23

GC content: 70.19

Gene sequence:

>822_bases
ATGTCACGACCGCTCGACCGGAGATCCGACGACAGGATCGAGGCGACCGGTGTCGAGGGGCGGCGCAGCGCCATCGTCGC
CTCGGTCCGCCAGCGCGGCTTCGTGACGATCGAGGCCCTGGCGGCGCAGTTCGGCGTCACCGTTCAGACGATCCGGCGCG
ACCTCAACGAACTGAGCGCCGAGGGCCGGCTGGAACGCTACCGCGGCGGCGGGGGACTGCCCTCCAGCGTCGAGAATATC
GACTACGCCGACCGCCGGGTGACCCTGCTGCCGGAGAAGAGCCGCATCGGCCGCCTCGCGGCGAGCCGCATCCCGTCGCA
CTGCTCGGTCTTCATCAACATCGGCACGACGCCGGAGGCCGTCGCCCGCGAGCTGGCCCGGCACGACGATCTCAGCATCA
TCACCAACAACCTCAACGTGGCGATCTCCCTCGCCGAGACGACCGAGTTCCGCATCGTCGTGGCGGGCGGAACCGTTCGG
AACCGCGACGGCGCGGTGCTGGGCCAGCTCACCTGCGACACGCTCAGCCAGTTCCGGGTCGACGTGGCGGTGATCGGCAT
CAGCGGCATCGACGGCGACGGGGCGCTCCTCGACTACGATTACGAGGAGGTGCGGGCGACGCAGACGATCCTGGCCCACG
CCCGGAAGACCTTCCTGGTGGCGGACCACACCAAGTTCACCCGCCGCCCGATGGTCCAGGTCGGGCGCCTGGAGCAGGTC
GACACCTTCTTCACGGACCGGCCTCCCCCGGCCGAGATCGTCGCGCTCATGGAGCGCCAGGGCGTCACCCTGGCGGTGGC
GGACGGCGCGGCCGAACCCTAA

Upstream 100 bases:

>100_bases
TCGCGCGAAAGCCGCGGCGCCCGGAAAATGTTCGCAAACGAACATCGCCCGATCATCAGTACAGCGGCGCGGCGGCCTGA
CGGAAGGCGAGGGAGCACCG

Downstream 100 bases:

>100_bases
CGAACATCGATTTTTTCGCTTGCGAAAGCCGAGGGCTGCGTCAATATACTGCCAATCCGCCAGCAGGGCGGCTCCGGAGG
AACCATGGCGGCAGCACCGG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSRPLDRRSDDRIEATGVEGRRSAIVASVRQRGFVTIEALAAQFGVTVQTIRRDLNELSAEGRLERYRGGGGLPSSVENI
DYADRRVTLLPEKSRIGRLAASRIPSHCSVFINIGTTPEAVARELARHDDLSIITNNLNVAISLAETTEFRIVVAGGTVR
NRDGAVLGQLTCDTLSQFRVDVAVIGISGIDGDGALLDYDYEEVRATQTILAHARKTFLVADHTKFTRRPMVQVGRLEQV
DTFFTDRPPPAEIVALMERQGVTLAVADGAAEP

Sequences:

>Translated_273_residues
MSRPLDRRSDDRIEATGVEGRRSAIVASVRQRGFVTIEALAAQFGVTVQTIRRDLNELSAEGRLERYRGGGGLPSSVENI
DYADRRVTLLPEKSRIGRLAASRIPSHCSVFINIGTTPEAVARELARHDDLSIITNNLNVAISLAETTEFRIVVAGGTVR
NRDGAVLGQLTCDTLSQFRVDVAVIGISGIDGDGALLDYDYEEVRATQTILAHARKTFLVADHTKFTRRPMVQVGRLEQV
DTFFTDRPPPAEIVALMERQGVTLAVADGAAEP
>Mature_272_residues
SRPLDRRSDDRIEATGVEGRRSAIVASVRQRGFVTIEALAAQFGVTVQTIRRDLNELSAEGRLERYRGGGGLPSSVENID
YADRRVTLLPEKSRIGRLAASRIPSHCSVFINIGTTPEAVARELARHDDLSIITNNLNVAISLAETTEFRIVVAGGTVRN
RDGAVLGQLTCDTLSQFRVDVAVIGISGIDGDGALLDYDYEEVRATQTILAHARKTFLVADHTKFTRRPMVQVGRLEQVD
TFFTDRPPPAEIVALMERQGVTLAVADGAAEP

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=46.5587044534413, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI87082344, Length=233, Percent_Identity=39.4849785407725, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1788069, Length=246, Percent_Identity=29.2682926829268, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=26.5873015873016, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI226510968, Length=248, Percent_Identity=27.4193548387097, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=26.8398268398268, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787063, Length=249, Percent_Identity=25.7028112449799, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1790635, Length=253, Percent_Identity=25.6916996047431, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787540, Length=252, Percent_Identity=24.6031746031746, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29767; Mature: 29636

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPLDRRSDDRIEATGVEGRRSAIVASVRQRGFVTIEALAAQFGVTVQTIRRDLNELSA
CCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCHHHHHHHHHHHHHH
EGRLERYRGGGGLPSSVENIDYADRRVTLLPEKSRIGRLAASRIPSHCSVFINIGTTPEA
CCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHH
VARELARHDDLSIITNNLNVAISLAETTEFRIVVAGGTVRNRDGAVLGQLTCDTLSQFRV
HHHHHHCCCCCEEEECCCEEEEEEECCCEEEEEEECCEEECCCCCEEEEEEHHHHHHHEE
DVAVIGISGIDGDGALLDYDYEEVRATQTILAHARKTFLVADHTKFTRRPMVQVGRLEQV
EEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCHHHHCHHHHHCCHHHH
DTFFTDRPPPAEIVALMERQGVTLAVADGAAEP
HHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure 
SRPLDRRSDDRIEATGVEGRRSAIVASVRQRGFVTIEALAAQFGVTVQTIRRDLNELSA
CCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEHHHHHHHHCCHHHHHHHHHHHHHH
EGRLERYRGGGGLPSSVENIDYADRRVTLLPEKSRIGRLAASRIPSHCSVFINIGTTPEA
CCCHHHHCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCHHH
VARELARHDDLSIITNNLNVAISLAETTEFRIVVAGGTVRNRDGAVLGQLTCDTLSQFRV
HHHHHHCCCCCEEEECCCEEEEEEECCCEEEEEEECCEEECCCCCEEEEEEHHHHHHHEE
DVAVIGISGIDGDGALLDYDYEEVRATQTILAHARKTFLVADHTKFTRRPMVQVGRLEQV
EEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHHHHEEEEECCCHHHHCHHHHHCCHHHH
DTFFTDRPPPAEIVALMERQGVTLAVADGAAEP
HHHHCCCCCHHHHHHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]