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The map label for this gene is oxyR [H]

Identifier: 170747065

GI number: 170747065

Start: 677600

End: 678535

Strand: Reverse

Name: oxyR [H]

Synonym: Mrad2831_0631

Alternate gene names: 170747065

Gene position: 678535-677600 (Counterclockwise)

Preceding gene: 170747068

Following gene: 170747064

Centisome position: 11.16

GC content: 74.25

Gene sequence:

>936_bases
ATGAACCTGGCCGGTCTCTCGCTCCGCGATCTCGAATATGTCGTCGCCGTCGCCGACGAGGGGCATTTCGGCCGGGCCGC
CGAGCGCTGCAACGTCAGCCAGCCGACGCTGAGCGTGCAGGTCCGTAAGCTGGAAACCGCGCTCGGCCTGACTTTGTTCG
AGCGGTCGAACCGGCGGATCCTGTTGACCGAAGCGGGGCAGGCCATCGTCCGGCAGGCGCGGGTCGTCCTGGCGGAGGCG
CAGCGTCTGCTGGCGCTGGCCAGCGAGGGCCGCGGCTCGCCGCTCACCGGGCGTCTCGTGCTGGCGGCGATCCAGACGCT
CGGTCCCTACTTCTTCCCGCTGGTGCTGCGGCCCCTGCGCGAGCAGTACCCCTTGCTGATGCTCTCGCTGTCGGAATCCC
GGACGGCCGACATCGTCGAGGGCCTGCGCGACGGCCGCATCGACGCGGCCCTGGTCTCGCTGCCGCTGCCGTCCCACGGG
CTCGCGGTCTCGCCGCTGTTCGTCGAGCCGTTCTGGCTCGCCTGCCCGGCCGAGCACGCCCTCGCCCGGGGCGGCGCGCT
CTCCGCGACCGAGATCGCCGGCCCGGATCTGCTGCTGCTCGACGAGGGCAACTGCCTGCGCGACCAGACGATCGCGGCCT
GCGGCGCCGGCTCCTCGGTCGGCCGCCACGCCACCAGCCTGGAGACGCTCCGCTCGATGGTGGCGGCCGGCGCCGGCTAC
ACGCTGCTCCCGGCCCTGGCGGTGCCGTCGAATCCCGATCCCAGCGGCCTGACGGTCACCCGCGCCTTCGACCTCGACGG
TCCCGGGCGGACCATCGCGCTGGTCTGGCGCGCGAGCGACCCGCGGGCCGCCGGGCTCGCGAGCCTGGCCGCCTTCTTCC
GCGCGCACGCGCCGGCGGGCACGGCCGCCTGCCGCGACGGCGAGACCGTCGCCTGA

Upstream 100 bases:

>100_bases
GACAGCGGGGTCAGCCTGGAACCGTTCTGGTGAAGGGTTATGACCGCGGCATGACCCCGAGGCAAATGCATCGTCACAAA
GGTTCTGATAGACGCAGCCT

Downstream 100 bases:

>100_bases
GCCGCCGCAAACGCCCGCATTATACAGTTGTGAATAGGAAGGCGGGCCGCGACGGGTCTATCAGGACCGAGACGGCAGGG
AGCGGCTCGATGCGGCGCAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MNLAGLSLRDLEYVVAVADEGHFGRAAERCNVSQPTLSVQVRKLETALGLTLFERSNRRILLTEAGQAIVRQARVVLAEA
QRLLALASEGRGSPLTGRLVLAAIQTLGPYFFPLVLRPLREQYPLLMLSLSESRTADIVEGLRDGRIDAALVSLPLPSHG
LAVSPLFVEPFWLACPAEHALARGGALSATEIAGPDLLLLDEGNCLRDQTIAACGAGSSVGRHATSLETLRSMVAAGAGY
TLLPALAVPSNPDPSGLTVTRAFDLDGPGRTIALVWRASDPRAAGLASLAAFFRAHAPAGTAACRDGETVA

Sequences:

>Translated_311_residues
MNLAGLSLRDLEYVVAVADEGHFGRAAERCNVSQPTLSVQVRKLETALGLTLFERSNRRILLTEAGQAIVRQARVVLAEA
QRLLALASEGRGSPLTGRLVLAAIQTLGPYFFPLVLRPLREQYPLLMLSLSESRTADIVEGLRDGRIDAALVSLPLPSHG
LAVSPLFVEPFWLACPAEHALARGGALSATEIAGPDLLLLDEGNCLRDQTIAACGAGSSVGRHATSLETLRSMVAAGAGY
TLLPALAVPSNPDPSGLTVTRAFDLDGPGRTIALVWRASDPRAAGLASLAAFFRAHAPAGTAACRDGETVA
>Mature_311_residues
MNLAGLSLRDLEYVVAVADEGHFGRAAERCNVSQPTLSVQVRKLETALGLTLFERSNRRILLTEAGQAIVRQARVVLAEA
QRLLALASEGRGSPLTGRLVLAAIQTLGPYFFPLVLRPLREQYPLLMLSLSESRTADIVEGLRDGRIDAALVSLPLPSHG
LAVSPLFVEPFWLACPAEHALARGGALSATEIAGPDLLLLDEGNCLRDQTIAACGAGSSVGRHATSLETLRSMVAAGAGY
TLLPALAVPSNPDPSGLTVTRAFDLDGPGRTIALVWRASDPRAAGLASLAAFFRAHAPAGTAACRDGETVA

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=293, Percent_Identity=42.6621160409556, Blast_Score=219, Evalue=1e-58,
Organism=Escherichia coli, GI1788748, Length=261, Percent_Identity=32.9501915708812, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788887, Length=288, Percent_Identity=28.4722222222222, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI157672245, Length=252, Percent_Identity=31.3492063492063, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787879, Length=255, Percent_Identity=30.9803921568627, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI2367136, Length=243, Percent_Identity=31.2757201646091, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787806, Length=299, Percent_Identity=27.0903010033445, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787530, Length=256, Percent_Identity=28.125, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1790208, Length=270, Percent_Identity=29.2592592592593, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=27.1255060728745, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786401, Length=158, Percent_Identity=32.2784810126582, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788481, Length=203, Percent_Identity=26.1083743842365, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788626, Length=245, Percent_Identity=30.2040816326531, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788296, Length=216, Percent_Identity=28.7037037037037, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790262, Length=266, Percent_Identity=26.6917293233083, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=301, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081904, Length=179, Percent_Identity=32.9608938547486, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787601, Length=180, Percent_Identity=25, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32656; Mature: 32656

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAGLSLRDLEYVVAVADEGHFGRAAERCNVSQPTLSVQVRKLETALGLTLFERSNRRI
CCCCCCCHHCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEHHHHHHHHCCCEEECCCCEE
LLTEAGQAIVRQARVVLAEAQRLLALASEGRGSPLTGRLVLAAIQTLGPYFFPLVLRPLR
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
EQYPLLMLSLSESRTADIVEGLRDGRIDAALVSLPLPSHGLAVSPLFVEPFWLACPAEHA
HCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCEECCEEEECCHHHH
LARGGALSATEIAGPDLLLLDEGNCLRDQTIAACGAGSSVGRHATSLETLRSMVAAGAGY
HHCCCCCCCHHCCCCCEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
TLLPALAVPSNPDPSGLTVTRAFDLDGPGRTIALVWRASDPRAAGLASLAAFFRAHAPAG
HHHHEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
TAACRDGETVA
CCCCCCCCCCC
>Mature Secondary Structure
MNLAGLSLRDLEYVVAVADEGHFGRAAERCNVSQPTLSVQVRKLETALGLTLFERSNRRI
CCCCCCCHHCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEHHHHHHHHCCCEEECCCCEE
LLTEAGQAIVRQARVVLAEAQRLLALASEGRGSPLTGRLVLAAIQTLGPYFFPLVLRPLR
EEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHH
EQYPLLMLSLSESRTADIVEGLRDGRIDAALVSLPLPSHGLAVSPLFVEPFWLACPAEHA
HCCCEEEEEECCCCHHHHHHHHHCCCCCEEEEECCCCCCCCEECCCEECCEEEECCHHHH
LARGGALSATEIAGPDLLLLDEGNCLRDQTIAACGAGSSVGRHATSLETLRSMVAAGAGY
HHCCCCCCCHHCCCCCEEEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCC
TLLPALAVPSNPDPSGLTVTRAFDLDGPGRTIALVWRASDPRAAGLASLAAFFRAHAPAG
HHHHEEECCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCC
TAACRDGETVA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA