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The map label for this gene is pdxA [H]

Identifier: 170746987

GI number: 170746987

Start: 593216

End: 594331

Strand: Reverse

Name: pdxA [H]

Synonym: Mrad2831_0553

Alternate gene names: 170746987

Gene position: 594331-593216 (Counterclockwise)

Preceding gene: 170746988

Following gene: 170746986

Centisome position: 9.78

GC content: 74.28

Gene sequence:

>1116_bases
ATGCCGCCCCTCGCCCTCACCCTCGGAGATCCCGCCGGCATCGGTCCGGAGCTGGCGCTCAGCGCGTGGCTCGGTCGGGG
CGGCGCAGATCCGCTGCCGCCCTTCTTCCTGGTGGCCGATTCGGACTTCGTCGAGCGCCTCGCTCACCGCCTCGACCGTC
CCGTGCCGGTGGCGGAGGTGGATCCCGAGACCGCCGCCGAGGTGTTCCCGCGCGCGCTCCCCGTGGTGCCCCTGCCGAGC
GGCGCCCGCGTCGCCGCCGAGCCGGGCGTACCCGATTCGGTGAATGCCGGCGCGACCATCGAGTCGATCACCGCGGCGGT
GGAGTTCGTGAAGGCCGGGCGCGCGAGCGCGGTGGTGACCAACCCGATCGCCAAGTTCGTGCTGACCCGGACGGGCTTCG
CCCATCCCGGGCACACCGAGTTCCTGGCCGCCCTCGCTGTGCCGCCCGGCGTGACGCCGCCCCGGCCGGTGATGATGATC
TGGAGCGCAGGCCTCTCGGTGGTGCCGGTGACGATCCACGTCCCGCTGAAGGACGTGCCGGACCTGCTCACCCAGGAGCT
CGTCGAGGAGACCGCCGCGATCGTCGCCCGTGACCTGCGGGAGCGGTTCGGCCTGCCCGAGCCGCGCCTCGTCCTCGCGG
GTCTGAACCCGCACGCGGGCGAGGCCGGGACGATCGGCCACGAGGACCGCGACGTCCTCGCCCCCGCGGTGGCACGGCTG
CGGGCGCGGGGCATCGACATCCGCGGGCCACTCCCCGCCGACACCCTGTTCCACGCCCGCGCCCGGGAGACCTACGACGT
CGCTCTCGCACCGACGCACGACCAGGCCCTCATCCCGATCAAGACGATCGCGTTCGACGACGGCGTGAACGTCACCCTCG
GCCTGCCGTTCGTGCGCACCTCCCCGGACCACGGCACGGCCTTCGACATCGCCGGTAAGGGCGTCGCCCGGCCCGACAGC
CTCGTGGCGGCCCTGCGCCTCGCCGACCGGCTGGCCGCCAACGCGGCGGCGCAGGACGAGGCCCCCGGCGGGGCCGAGAT
CATCCCGTTCAGCGTCTATGCCGGCCGGCCGCGCCCTGCGGGGGCCCGCCATTTCGATCCCGAGGACGAGCTGTGA

Upstream 100 bases:

>100_bases
GTCGCGGTCCCATCGCGCGCCGGGCGGCGGGATCCGGCTCCGCGCACGGCCGCGCTCTGCCGAGGATGCGCCCGCGCCGC
GCGGGCGCTATAGAGCGCCC

Downstream 100 bases:

>100_bases
GGGACCCAGCATGAGCGCCGGGGACGGGCTTCCGCCGCTGCGCGAGGTGGTCGCCCGCCACGGCCTGGAGCCGAAGAAGG
CGCTCGGCCAGAACTTCCTC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MPPLALTLGDPAGIGPELALSAWLGRGGADPLPPFFLVADSDFVERLAHRLDRPVPVAEVDPETAAEVFPRALPVVPLPS
GARVAAEPGVPDSVNAGATIESITAAVEFVKAGRASAVVTNPIAKFVLTRTGFAHPGHTEFLAALAVPPGVTPPRPVMMI
WSAGLSVVPVTIHVPLKDVPDLLTQELVEETAAIVARDLRERFGLPEPRLVLAGLNPHAGEAGTIGHEDRDVLAPAVARL
RARGIDIRGPLPADTLFHARARETYDVALAPTHDQALIPIKTIAFDDGVNVTLGLPFVRTSPDHGTAFDIAGKGVARPDS
LVAALRLADRLAANAAAQDEAPGGAEIIPFSVYAGRPRPAGARHFDPEDEL

Sequences:

>Translated_371_residues
MPPLALTLGDPAGIGPELALSAWLGRGGADPLPPFFLVADSDFVERLAHRLDRPVPVAEVDPETAAEVFPRALPVVPLPS
GARVAAEPGVPDSVNAGATIESITAAVEFVKAGRASAVVTNPIAKFVLTRTGFAHPGHTEFLAALAVPPGVTPPRPVMMI
WSAGLSVVPVTIHVPLKDVPDLLTQELVEETAAIVARDLRERFGLPEPRLVLAGLNPHAGEAGTIGHEDRDVLAPAVARL
RARGIDIRGPLPADTLFHARARETYDVALAPTHDQALIPIKTIAFDDGVNVTLGLPFVRTSPDHGTAFDIAGKGVARPDS
LVAALRLADRLAANAAAQDEAPGGAEIIPFSVYAGRPRPAGARHFDPEDEL
>Mature_370_residues
PPLALTLGDPAGIGPELALSAWLGRGGADPLPPFFLVADSDFVERLAHRLDRPVPVAEVDPETAAEVFPRALPVVPLPSG
ARVAAEPGVPDSVNAGATIESITAAVEFVKAGRASAVVTNPIAKFVLTRTGFAHPGHTEFLAALAVPPGVTPPRPVMMIW
SAGLSVVPVTIHVPLKDVPDLLTQELVEETAAIVARDLRERFGLPEPRLVLAGLNPHAGEAGTIGHEDRDVLAPAVARLR
ARGIDIRGPLPADTLFHARARETYDVALAPTHDQALIPIKTIAFDDGVNVTLGLPFVRTSPDHGTAFDIAGKGVARPDSL
VAALRLADRLAANAAAQDEAPGGAEIIPFSVYAGRPRPAGARHFDPEDEL

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=336, Percent_Identity=37.797619047619, Blast_Score=204, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 38806; Mature: 38675

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPLALTLGDPAGIGPELALSAWLGRGGADPLPPFFLVADSDFVERLAHRLDRPVPVAEV
CCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCC
DPETAAEVFPRALPVVPLPSGARVAAEPGVPDSVNAGATIESITAAVEFVKAGRASAVVT
CCHHHHHHHHHHCCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHH
NPIAKFVLTRTGFAHPGHTEFLAALAVPPGVTPPRPVMMIWSAGLSVVPVTIHVPLKDVP
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEEEECHHHHH
DLLTQELVEETAAIVARDLRERFGLPEPRLVLAGLNPHAGEAGTIGHEDRDVLAPAVARL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
RARGIDIRGPLPADTLFHARARETYDVALAPTHDQALIPIKTIAFDDGVNVTLGLPFVRT
HHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEECCCCEEEEECCEEEC
SPDHGTAFDIAGKGVARPDSLVAALRLADRLAANAAAQDEAPGGAEIIPFSVYAGRPRPA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCC
GARHFDPEDEL
CCCCCCCCCCC
>Mature Secondary Structure 
PPLALTLGDPAGIGPELALSAWLGRGGADPLPPFFLVADSDFVERLAHRLDRPVPVAEV
CCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCC
DPETAAEVFPRALPVVPLPSGARVAAEPGVPDSVNAGATIESITAAVEFVKAGRASAVVT
CCHHHHHHHHHHCCCEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHH
NPIAKFVLTRTGFAHPGHTEFLAALAVPPGVTPPRPVMMIWSAGLSVVPVTIHVPLKDVP
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCEEEEEEEEECHHHHH
DLLTQELVEETAAIVARDLRERFGLPEPRLVLAGLNPHAGEAGTIGHEDRDVLAPAVARL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
RARGIDIRGPLPADTLFHARARETYDVALAPTHDQALIPIKTIAFDDGVNVTLGLPFVRT
HHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEEECCCCEEEEECCEEEC
SPDHGTAFDIAGKGVARPDSLVAALRLADRLAANAAAQDEAPGGAEIIPFSVYAGRPRPA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCCC
GARHFDPEDEL
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA