Click here to switch to the map view.

The map label for this gene is dsdA [H]

Identifier: 170746681

GI number: 170746681

Start: 248206

End: 249495

Strand: Reverse

Name: dsdA [H]

Synonym: Mrad2831_0232

Alternate gene names: 170746681

Gene position: 249495-248206 (Counterclockwise)

Preceding gene: 170746683

Following gene: 170746680

Centisome position: 4.1

GC content: 73.72

Gene sequence:

>1290_bases
ATGGCAGCGGCCGTCGAGATGCAGTCCCGACAGTGGGGCGACCGGATCCCGGAGGCCGTCAGGCATGCCAGCCCCGCGGT
CTGGACGAACCCGTCGCTGACCGCCACCGCCTCCGTGCTGCCCAATCTGGCGATCGGCCGCGCCGACGTGGACGGGGCCG
TGGCGCGCTGGAACCGGTTCGCACCGCTTCTCGCCCGGCTGTTCCCTGAAGAGGGTGCCGGCCGGATCGACTCGCCGCTC
GTCCCGCTCGACGGACCGCTGGCCCGGGACATCTTGGACGGGGCCGCCGGGCGCGTGCTCGTGAAGGCCGACCACGCGCT
GCCGGTGACCGGCTGCATCAAGGCGCGCGGCGGCGTCTACGAGGTCCTGGCCTACGCCGAGGAACTGGCCCGACGGGCCG
GCCTGCTCGCCGAGGGGCAAACCTACGCGGCCTTCGCCGATCCGGACTTCCGCGCCCTGTTCGCCCGCCACATCATCGCG
GTCGGCAGCACCGGCAACCTCGGGTTCAGCGTCGGCCTGATGGGCCGGGCGCTCGGCTTCGCGGTGGAGGTTCACATGTC
CCACGACGCCAAGGCGTGGAAGAAGCAGCGCCTGCGCGAACTCGGCGCCCGCGTCGTCGAGCATCGCGGCGATTACGGCG
CCGCGGTCGCGGCGGCGCGCGGCGCCTTTGCCGGCCGGGCCGACGCCCATTTCGTCGACGACGAGGATTCGGTCGATCTG
TTCCTCGGCTACGCGGCCGCGGCCCTCGACCTGCAGCGGCAGCTCGCGGAGGCCGGTATCGCGGTGGGGCCGGCGCATCC
CCTGTTCGTCTACCTGCCCTGCGGCGTCGGCGGTGCGCCGGGCGGCGTCGCCTTCGGGCTGAAGCTGCTGTTCGGCGACG
TGGTGCACCCGGTTTTCGTCGAGCCGGTCGCGTCCCCGTGCATGCTGGTCCAGCTGGCCGCCGGCCTCGACCGCTCGGTC
AGCGTCTACGATGTCGGCCTCGACAATCGCACCGCGGCGGACGGGCTGGCCTGCGCCTCCGCGTCGATGCTCGTCGCCCG
GACGCTGGAGAAGCTCGTCGCGGCCGTGGTCACGGTGCCCGACGACGCGCTCTATCACTGGCTCAAGGTGATGTGGACCG
AGGCCGCCGTTCGCCTGGAGCCTTCGGCGGCGGCCGGCTTCGCGGCTGCCGGGCGCTTCGCCGCCACACTGCCCGCGGAG
GCGCGCGCCGACGCCACCCACGTGATCTGGACGACGGGCGGCGCGCACCTCCCGGCCGAGGAGTTCGAGGCGGCCCTCGC
CCGCGGCTGA

Upstream 100 bases:

>100_bases
ATAAGCTGGCCTAATAGGCTGCACCAGAGAATATAATTGGCCGCCCCTCGGTCTTTCGCGCAGGTTCGGCGCGCACGTAC
CCAGCAGGATCGGAAGCGCC

Downstream 100 bases:

>100_bases
GGCGCGAGCCGGCGCATCGATGCCGGCTGAGGATCGGAGAACGCGCGGCCCTCGGCGCCGCGTGCACGGGCGGCCGAGCC
CGACTCGGCAACCTGCGCGG

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MAAAVEMQSRQWGDRIPEAVRHASPAVWTNPSLTATASVLPNLAIGRADVDGAVARWNRFAPLLARLFPEEGAGRIDSPL
VPLDGPLARDILDGAAGRVLVKADHALPVTGCIKARGGVYEVLAYAEELARRAGLLAEGQTYAAFADPDFRALFARHIIA
VGSTGNLGFSVGLMGRALGFAVEVHMSHDAKAWKKQRLRELGARVVEHRGDYGAAVAAARGAFAGRADAHFVDDEDSVDL
FLGYAAAALDLQRQLAEAGIAVGPAHPLFVYLPCGVGGAPGGVAFGLKLLFGDVVHPVFVEPVASPCMLVQLAAGLDRSV
SVYDVGLDNRTAADGLACASASMLVARTLEKLVAAVVTVPDDALYHWLKVMWTEAAVRLEPSAAAGFAAAGRFAATLPAE
ARADATHVIWTTGGAHLPAEEFEAALARG

Sequences:

>Translated_429_residues
MAAAVEMQSRQWGDRIPEAVRHASPAVWTNPSLTATASVLPNLAIGRADVDGAVARWNRFAPLLARLFPEEGAGRIDSPL
VPLDGPLARDILDGAAGRVLVKADHALPVTGCIKARGGVYEVLAYAEELARRAGLLAEGQTYAAFADPDFRALFARHIIA
VGSTGNLGFSVGLMGRALGFAVEVHMSHDAKAWKKQRLRELGARVVEHRGDYGAAVAAARGAFAGRADAHFVDDEDSVDL
FLGYAAAALDLQRQLAEAGIAVGPAHPLFVYLPCGVGGAPGGVAFGLKLLFGDVVHPVFVEPVASPCMLVQLAAGLDRSV
SVYDVGLDNRTAADGLACASASMLVARTLEKLVAAVVTVPDDALYHWLKVMWTEAAVRLEPSAAAGFAAAGRFAATLPAE
ARADATHVIWTTGGAHLPAEEFEAALARG
>Mature_428_residues
AAAVEMQSRQWGDRIPEAVRHASPAVWTNPSLTATASVLPNLAIGRADVDGAVARWNRFAPLLARLFPEEGAGRIDSPLV
PLDGPLARDILDGAAGRVLVKADHALPVTGCIKARGGVYEVLAYAEELARRAGLLAEGQTYAAFADPDFRALFARHIIAV
GSTGNLGFSVGLMGRALGFAVEVHMSHDAKAWKKQRLRELGARVVEHRGDYGAAVAAARGAFAGRADAHFVDDEDSVDLF
LGYAAAALDLQRQLAEAGIAVGPAHPLFVYLPCGVGGAPGGVAFGLKLLFGDVVHPVFVEPVASPCMLVQLAAGLDRSVS
VYDVGLDNRTAADGLACASASMLVARTLEKLVAAVVTVPDDALYHWLKVMWTEAAVRLEPSAAAGFAAAGRFAATLPAEA
RADATHVIWTTGGAHLPAEEFEAALARG

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788708, Length=417, Percent_Identity=47.7218225419664, Blast_Score=352, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011780
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.18 [H]

Molecular weight: Translated: 44814; Mature: 44682

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAVEMQSRQWGDRIPEAVRHASPAVWTNPSLTATASVLPNLAIGRADVDGAVARWNRF
CCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
APLLARLFPEEGAGRIDSPLVPLDGPLARDILDGAAGRVLVKADHALPVTGCIKARGGVY
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCCCHH
EVLAYAEELARRAGLLAEGQTYAAFADPDFRALFARHIIAVGSTGNLGFSVGLMGRALGF
HHHHHHHHHHHHCCCEECCCEEEEECCCHHHHHHHHHHHEECCCCCCCEEHHHHHHHHEE
AVEVHMSHDAKAWKKQRLRELGARVVEHRGDYGAAVAAARGAFAGRADAHFVDDEDSVDL
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHH
FLGYAAAALDLQRQLAEAGIAVGPAHPLFVYLPCGVGGAPGGVAFGLKLLFGDVVHPVFV
HHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
EPVASPCMLVQLAAGLDRSVSVYDVGLDNRTAADGLACASASMLVARTLEKLVAAVVTVP
HHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DDALYHWLKVMWTEAAVRLEPSAAAGFAAAGRFAATLPAEARADATHVIWTTGGAHLPAE
CHHHHHHHHHHHHHHHEEECCCHHCCHHHHCCHHEECCCCCCCCCEEEEEECCCCCCCHH
EFEAALARG
HHHHHHHCC
>Mature Secondary Structure 
AAAVEMQSRQWGDRIPEAVRHASPAVWTNPSLTATASVLPNLAIGRADVDGAVARWNRF
CCCHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHH
APLLARLFPEEGAGRIDSPLVPLDGPLARDILDGAAGRVLVKADHALPVTGCIKARGGVY
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHCCCCHH
EVLAYAEELARRAGLLAEGQTYAAFADPDFRALFARHIIAVGSTGNLGFSVGLMGRALGF
HHHHHHHHHHHHCCCEECCCEEEEECCCHHHHHHHHHHHEECCCCCCCEEHHHHHHHHEE
AVEVHMSHDAKAWKKQRLRELGARVVEHRGDYGAAVAAARGAFAGRADAHFVDDEDSVDL
EEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHH
FLGYAAAALDLQRQLAEAGIAVGPAHPLFVYLPCGVGGAPGGVAFGLKLLFGDVVHPVFV
HHHHHHHHHHHHHHHHHCCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
EPVASPCMLVQLAAGLDRSVSVYDVGLDNRTAADGLACASASMLVARTLEKLVAAVVTVP
HHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
DDALYHWLKVMWTEAAVRLEPSAAAGFAAAGRFAATLPAEARADATHVIWTTGGAHLPAE
CHHHHHHHHHHHHHHHEEECCCHHCCHHHHCCHHEECCCCCCCCCEEEEEECCCCCCCHH
EFEAALARG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA