Click here to switch to the map view.

The map label for this gene is exuT [H]

Identifier: 170746680

GI number: 170746680

Start: 246834

End: 248063

Strand: Reverse

Name: exuT [H]

Synonym: Mrad2831_0231

Alternate gene names: 170746680

Gene position: 248063-246834 (Counterclockwise)

Preceding gene: 170746681

Following gene: 170746679

Centisome position: 4.08

GC content: 66.75

Gene sequence:

>1230_bases
ATGGACCCCGCCCAGCCCGCGCGACCGGGCCGACCCTATCTGGGGTTCGCGCTGCTGTACGCCGCCTACTGCATCTCCTA
CGTGGACCGCGCCGCGATCGCGCTGGCCCTGACCCAGATCGGGCGGGAGTTCGGCCTCAGTCCGACCGAGTACGGCGTGA
TCCTGAGCGTCTTCTTCTTCGGTTACTCGCTGATGCAGCTGCCCGGCGGCTGGCTCGCGGACCGGTTCGGGTCGAAATAC
GTCGTCATCGGCACGGCCGTCGCGTGGTCGATCTTCACCGCGCTGACCGGGCTCGCGTGGTCGTTCACGTCCCTGATCGT
CATCCGGCTGATCTTCGGTCTGGCCGAGGGCGGCTTTCCGGCGGCCTGCATCAAGGCGGTCTCGGAGCAGTTCACCGGAC
CGGCACGCCCGAAGATGTCGTCGCTGATGATCTCGTCGAACTACGTCGGAAGCCTGCTCGCGCCCCTGGTGATGGCCCCG
CTGCTGATCTATTTCGGCTGGCGCCACGCCTTCTTCATCGTCGGCGCCGCGGGCCTCATCTTCGGGCTCGTCTATGACCG
CATGATCCCGCACCGCCCCCCCGCAGAGGTCCCCGGCGCAGCCCGCGCCGGACGCGGCCCGTCGGCTCCGGCGCGCGAAC
TCCTGCGCAACCCGCTCCTGTGGCAGCTGATGCTCGTCTGGTTCGGCCTCGGCTGCATCAACAAGGGCCTCGACGCGTGG
ATGCCGACCTACCTGCTCCAGGCGCGCGGTCTCGACCTCAAGGCGGTCGGCCTGCTGACGCCCCTCCCCTTCATCATGGC
GAGCATCGCGACGGCGATCGGCGGCTGGGTCATGATCCGGTTCTTCGATGGCCGGGAAAAATACATGATCGTGGTCAGCA
CGATGCTGACCGGAATCTTCCTCTATCTGATGTACCAGGCACCGACGATCGCGGGCGTGATCACCTTCCAGTCGATCACC
TACTTCTTCAAATCGTTCGTCTTCGCCGCGGCCTTCGCCCTCCCGACCAAGCTCATGCGGGACGATCAGATCGGCACCAG
CATCGGCATGGTCAATCTGGGAGGCCAGTGCGCCGGCTTCATCGCGCCCCTGGTGATGGGCCTGCTGGTCGATCACTACG
GCACTTACGACGCCGCGTTCGACTTCCTGTTGACCGCCGCCGCCGTTGCGACCCTGGTCGCATTGACCATCCGGAGCCGC
TCGACCGCCGCCGTGCCGCAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCGCGGCCCTCGGCGCCGCGTGCACGGGCGGCCGAGCCCGACTCGGCAACCTGCGCGGGGTTTCGGCTCCGCGCGCGCTT
TATCGAACCGGAGCCAGACC

Downstream 100 bases:

>100_bases
CGAAGTTTCCCATCGATCCGCGTGCCGAATTCTGACGGAGATGACGCCGTGACCGACCTTTGCGACATGTCCGCGGTGGA
CCTGCGCCGCCTCATCGGGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MDPAQPARPGRPYLGFALLYAAYCISYVDRAAIALALTQIGREFGLSPTEYGVILSVFFFGYSLMQLPGGWLADRFGSKY
VVIGTAVAWSIFTALTGLAWSFTSLIVIRLIFGLAEGGFPAACIKAVSEQFTGPARPKMSSLMISSNYVGSLLAPLVMAP
LLIYFGWRHAFFIVGAAGLIFGLVYDRMIPHRPPAEVPGAARAGRGPSAPARELLRNPLLWQLMLVWFGLGCINKGLDAW
MPTYLLQARGLDLKAVGLLTPLPFIMASIATAIGGWVMIRFFDGREKYMIVVSTMLTGIFLYLMYQAPTIAGVITFQSIT
YFFKSFVFAAAFALPTKLMRDDQIGTSIGMVNLGGQCAGFIAPLVMGLLVDHYGTYDAAFDFLLTAAAVATLVALTIRSR
STAAVPQAA

Sequences:

>Translated_409_residues
MDPAQPARPGRPYLGFALLYAAYCISYVDRAAIALALTQIGREFGLSPTEYGVILSVFFFGYSLMQLPGGWLADRFGSKY
VVIGTAVAWSIFTALTGLAWSFTSLIVIRLIFGLAEGGFPAACIKAVSEQFTGPARPKMSSLMISSNYVGSLLAPLVMAP
LLIYFGWRHAFFIVGAAGLIFGLVYDRMIPHRPPAEVPGAARAGRGPSAPARELLRNPLLWQLMLVWFGLGCINKGLDAW
MPTYLLQARGLDLKAVGLLTPLPFIMASIATAIGGWVMIRFFDGREKYMIVVSTMLTGIFLYLMYQAPTIAGVITFQSIT
YFFKSFVFAAAFALPTKLMRDDQIGTSIGMVNLGGQCAGFIAPLVMGLLVDHYGTYDAAFDFLLTAAAVATLVALTIRSR
STAAVPQAA
>Mature_409_residues
MDPAQPARPGRPYLGFALLYAAYCISYVDRAAIALALTQIGREFGLSPTEYGVILSVFFFGYSLMQLPGGWLADRFGSKY
VVIGTAVAWSIFTALTGLAWSFTSLIVIRLIFGLAEGGFPAACIKAVSEQFTGPARPKMSSLMISSNYVGSLLAPLVMAP
LLIYFGWRHAFFIVGAAGLIFGLVYDRMIPHRPPAEVPGAARAGRGPSAPARELLRNPLLWQLMLVWFGLGCINKGLDAW
MPTYLLQARGLDLKAVGLLTPLPFIMASIATAIGGWVMIRFFDGREKYMIVVSTMLTGIFLYLMYQAPTIAGVITFQSIT
YFFKSFVFAAAFALPTKLMRDDQIGTSIGMVNLGGQCAGFIAPLVMGLLVDHYGTYDAAFDFLLTAAAVATLVALTIRSR
STAAVPQAA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=349, Percent_Identity=25.7879656160458, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI6912666, Length=266, Percent_Identity=25.5639097744361, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4885441, Length=376, Percent_Identity=24.2021276595745, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI9945322, Length=407, Percent_Identity=21.3759213759214, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI9966811, Length=411, Percent_Identity=20.9245742092457, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI148743791, Length=332, Percent_Identity=24.6987951807229, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI5031955, Length=252, Percent_Identity=27.3809523809524, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI2367379, Length=382, Percent_Identity=26.9633507853403, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789515, Length=437, Percent_Identity=26.7734553775744, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1789152, Length=429, Percent_Identity=26.5734265734266, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=28.8372093023256, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI2367193, Length=381, Percent_Identity=23.0971128608924, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082071, Length=423, Percent_Identity=25.531914893617, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082310, Length=326, Percent_Identity=21.4723926380368, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082231, Length=200, Percent_Identity=28.5, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=258, Percent_Identity=23.6434108527132, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=285, Percent_Identity=25.2631578947368, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=285, Percent_Identity=25.2631578947368, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17552542, Length=261, Percent_Identity=25.6704980842912, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920686, Length=248, Percent_Identity=26.6129032258064, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24583789, Length=264, Percent_Identity=28.030303030303, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24641682, Length=400, Percent_Identity=23.25, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648416, Length=260, Percent_Identity=25.3846153846154, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356189, Length=260, Percent_Identity=25.3846153846154, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24584153, Length=356, Percent_Identity=22.752808988764, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI45550460, Length=416, Percent_Identity=23.0769230769231, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24655255, Length=372, Percent_Identity=23.9247311827957, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI45550364, Length=279, Percent_Identity=25.4480286738351, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281361682, Length=377, Percent_Identity=26.790450928382, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI20130167, Length=383, Percent_Identity=22.1932114882507, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44163; Mature: 44163

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]