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The map label for this gene is bdlA [H]

Identifier: 170746647

GI number: 170746647

Start: 203242

End: 204726

Strand: Reverse

Name: bdlA [H]

Synonym: Mrad2831_0198

Alternate gene names: 170746647

Gene position: 204726-203242 (Counterclockwise)

Preceding gene: 170746648

Following gene: 170746645

Centisome position: 3.37

GC content: 69.63

Gene sequence:

>1485_bases
ATGTTCGAGGGCGCGAAGGTTCGGAGAGATCAGGCTGCCAAGCTCGCGGCCCTCAGCCGGTCCCTGGCCACGATCGAATT
CGCGTTGGACGGCACGATCCTCGACGCGAACCCGAATTTCCTGGCGACGGTGGGCTACACGCTCGAGGAGATCCGTGGCC
GGCATCACAGCCTCTTCGTTCCGCCGTCCGAGCTGGGGAGCGACGCCTATCGGGAGTTCTGGGACAGCCTGCGACGCGGC
ACCTTCGCCAGTGCCGAGTACAAGCGGCTCGCCAAGGGTGGACGGGAGGTCTGGATCCAGGCCTCCTACAACCCGGTGCT
CGACGCCAGCGGCAAGCCAGTGAAGATCGTCAAGTTCGCCACGGACATCACTGACCAGAAGCTCCGCGCCCTCGATCTCG
AAGGGCAGATCAGCGCGCTGCACCGCTCGCAAGCGGTGATCGCCTTCTCGCTAGACGGCACGATCCTGACCGCCAACGCC
AATTTCCTCGATGCCGTGGGCTATCGGCTCGACGAGATCGTCGGTCGGCATCACAGCCTGTTCGTCGGCGAGGCGGAGCG
CGTCGGCGAGGAGTACCGGATGTTCTGGGCCGCACTCGCGCGAGGGGAGTTCCAGTCCGGCGCGTTCAGGCGCACCGGCA
AAGGCGGTCGCGAGATCTGGATCCAGGCGACCTACAACCCGATCACGGACGCGGATGGACGGCCCGTCCGGGTCGTCAAG
TTCGCCACAGACATCACCGCCCAGGTCCACGAACGGCAGCAGCGCGCCGCCGCGCAGCGCGCCATCGGCGCGGAGCTGGA
CGCCATCGGCGACGCCGTGGCGAACGTGACCCGGCAAGCCGACGCGGCGGTCGCGCGCGTGGGCCGCGTGTCCGGCGACA
TCCGGTCGGTGGCCACCGGCGCTGAGCAACTGTCGGCCTCGGTGGACGAGATCAGCCAGCAAGTGAGCCACGCCGCCGAG
ACGGCCGGGCAAGCCGTGGAGCAGGCGCAGCGCACCGGCCGGATCGTGACGGGCCTCAGCGACCAGGCCGCCCAGATCGG
CGAGGTTCTGGGCCTCATCTCCGGCATCGCCGCGCAGACGAACCTGCTCGCGCTCAACGCCACCATCGAGGCGGCCCGCG
CCGGCGAGGCCGGTCGCGGCTTCGCGGTGGTGGCGTCGGAGGTGAAGATTCTGGCGGCGCAGACCGGCCGCGCGACGGAT
CAGATCCGCCACCAGATCGCCTCGACGCAGGCGGCGACCCGCGAAGCCGTCGACGCCATCGACGCGATCCAGGGCACGAT
CCGGACATTGAACGCGGTCTCGTCGACCATCGCGGCGGCGGTAGAGGAGCAATCCGCGGTGATGCGCGAGATGTCGGGCA
GCATGCAGACCGCTGCGGAGGACGTCTCGGCGATTTCCGGCGGGATGACCACGATCGCGCAGGCGAGCGGCCGGGCGGAC
CGAGCGGCGCGGCAGGTCCGGGAGACCGCCCGGGCCTTCGGGTGA

Upstream 100 bases:

>100_bases
GCCCAGCCCGATAGAAGGCGGACTCGGTCAAGAAGATCTTGATCTGACCGCCCAGGTGCGCGTTTCGGCCGCACCCTCAT
CACGGGATGCGGAGGAATCG

Downstream 100 bases:

>100_bases
GGCGATCCGCGCGTTCGACGCCGGCTCAGGGCGGTTCGGCGCCTTCGTCCGCGCGCTCGTCCTCGACCAAGCGCCCGATC
CGCGGGATCAGCGGGCAGTC

Product: methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MFEGAKVRRDQAAKLAALSRSLATIEFALDGTILDANPNFLATVGYTLEEIRGRHHSLFVPPSELGSDAYREFWDSLRRG
TFASAEYKRLAKGGREVWIQASYNPVLDASGKPVKIVKFATDITDQKLRALDLEGQISALHRSQAVIAFSLDGTILTANA
NFLDAVGYRLDEIVGRHHSLFVGEAERVGEEYRMFWAALARGEFQSGAFRRTGKGGREIWIQATYNPITDADGRPVRVVK
FATDITAQVHERQQRAAAQRAIGAELDAIGDAVANVTRQADAAVARVGRVSGDIRSVATGAEQLSASVDEISQQVSHAAE
TAGQAVEQAQRTGRIVTGLSDQAAQIGEVLGLISGIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKILAAQTGRATD
QIRHQIASTQAATREAVDAIDAIQGTIRTLNAVSSTIAAAVEEQSAVMREMSGSMQTAAEDVSAISGGMTTIAQASGRAD
RAARQVRETARAFG

Sequences:

>Translated_494_residues
MFEGAKVRRDQAAKLAALSRSLATIEFALDGTILDANPNFLATVGYTLEEIRGRHHSLFVPPSELGSDAYREFWDSLRRG
TFASAEYKRLAKGGREVWIQASYNPVLDASGKPVKIVKFATDITDQKLRALDLEGQISALHRSQAVIAFSLDGTILTANA
NFLDAVGYRLDEIVGRHHSLFVGEAERVGEEYRMFWAALARGEFQSGAFRRTGKGGREIWIQATYNPITDADGRPVRVVK
FATDITAQVHERQQRAAAQRAIGAELDAIGDAVANVTRQADAAVARVGRVSGDIRSVATGAEQLSASVDEISQQVSHAAE
TAGQAVEQAQRTGRIVTGLSDQAAQIGEVLGLISGIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKILAAQTGRATD
QIRHQIASTQAATREAVDAIDAIQGTIRTLNAVSSTIAAAVEEQSAVMREMSGSMQTAAEDVSAISGGMTTIAQASGRAD
RAARQVRETARAFG
>Mature_494_residues
MFEGAKVRRDQAAKLAALSRSLATIEFALDGTILDANPNFLATVGYTLEEIRGRHHSLFVPPSELGSDAYREFWDSLRRG
TFASAEYKRLAKGGREVWIQASYNPVLDASGKPVKIVKFATDITDQKLRALDLEGQISALHRSQAVIAFSLDGTILTANA
NFLDAVGYRLDEIVGRHHSLFVGEAERVGEEYRMFWAALARGEFQSGAFRRTGKGGREIWIQATYNPITDADGRPVRVVK
FATDITAQVHERQQRAAAQRAIGAELDAIGDAVANVTRQADAAVARVGRVSGDIRSVATGAEQLSASVDEISQQVSHAAE
TAGQAVEQAQRTGRIVTGLSDQAAQIGEVLGLISGIAAQTNLLALNATIEAARAGEAGRGFAVVASEVKILAAQTGRATD
QIRHQIASTQAATREAVDAIDAIQGTIRTLNAVSSTIAAAVEEQSAVMREMSGSMQTAAEDVSAISGGMTTIAQASGRAD
RAARQVRETARAFG

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=199, Percent_Identity=37.1859296482412, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788195, Length=199, Percent_Identity=32.6633165829146, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI2367378, Length=129, Percent_Identity=40.3100775193798, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788194, Length=175, Percent_Identity=35.4285714285714, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1789453, Length=126, Percent_Identity=40.4761904761905, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 52543; Mature: 52543

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEGAKVRRDQAAKLAALSRSLATIEFALDGTILDANPNFLATVGYTLEEIRGRHHSLFV
CCCCCCCCHHHHHHHHHHHHHHHEEEEEECCEEEECCCCEEEECCCHHHHHCCCCCEEEC
PPSELGSDAYREFWDSLRRGTFASAEYKRLAKGGREVWIQASYNPVLDASGKPVKIVKFA
CHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEE
TDITDQKLRALDLEGQISALHRSQAVIAFSLDGTILTANANFLDAVGYRLDEIVGRHHSL
CCCCHHHHHHCCCCCHHHHHHCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCEE
FVGEAERVGEEYRMFWAALARGEFQSGAFRRTGKGGREIWIQATYNPITDADGRPVRVVK
EECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEE
FATDITAQVHERQQRAAAQRAIGAELDAIGDAVANVTRQADAAVARVGRVSGDIRSVATG
EHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AEQLSASVDEISQQVSHAAETAGQAVEQAQRTGRIVTGLSDQAAQIGEVLGLISGIAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHC
NLLALNATIEAARAGEAGRGFAVVASEVKILAAQTGRATDQIRHQIASTQAATREAVDAI
EEEEEECHHHHHHCCCCCCCCEEEHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
DAIQGTIRTLNAVSSTIAAAVEEQSAVMREMSGSMQTAAEDVSAISGGMTTIAQASGRAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCHH
RAARQVRETARAFG
HHHHHHHHHHHHCC
>Mature Secondary Structure
MFEGAKVRRDQAAKLAALSRSLATIEFALDGTILDANPNFLATVGYTLEEIRGRHHSLFV
CCCCCCCCHHHHHHHHHHHHHHHEEEEEECCEEEECCCCEEEECCCHHHHHCCCCCEEEC
PPSELGSDAYREFWDSLRRGTFASAEYKRLAKGGREVWIQASYNPVLDASGKPVKIVKFA
CHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEEE
TDITDQKLRALDLEGQISALHRSQAVIAFSLDGTILTANANFLDAVGYRLDEIVGRHHSL
CCCCHHHHHHCCCCCHHHHHHCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHCCCCEE
FVGEAERVGEEYRMFWAALARGEFQSGAFRRTGKGGREIWIQATYNPITDADGRPVRVVK
EECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEE
FATDITAQVHERQQRAAAQRAIGAELDAIGDAVANVTRQADAAVARVGRVSGDIRSVATG
EHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AEQLSASVDEISQQVSHAAETAGQAVEQAQRTGRIVTGLSDQAAQIGEVLGLISGIAAQT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHC
NLLALNATIEAARAGEAGRGFAVVASEVKILAAQTGRATDQIRHQIASTQAATREAVDAI
EEEEEECHHHHHHCCCCCCCCEEEHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
DAIQGTIRTLNAVSSTIAAAVEEQSAVMREMSGSMQTAAEDVSAISGGMTTIAQASGRAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHCCCHH
RAARQVRETARAFG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]