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The map label for this gene is aer [C]

Identifier: 170746645

GI number: 170746645

Start: 199181

End: 200887

Strand: Reverse

Name: aer [C]

Synonym: Mrad2831_0196

Alternate gene names: 170746645

Gene position: 200887-199181 (Counterclockwise)

Preceding gene: 170746647

Following gene: 170746644

Centisome position: 3.31

GC content: 70.77

Gene sequence:

>1707_bases
ATGGTGTCTTTCCCTATTCTGCGCGATGATCACTATGATTTGGGTTTCAGGACCTTCGTGATCGGCTTCACGGCCTCGTT
GTTGTGTATTCCCTTCGCATTCGGTTGCGTTTCGGCATTTCAATTTGGCACCATCGACTCCTCCAGTCGGTCTCTGGTCA
GAGAGATCGAAGTTGTCAGGCTTCTCGGCACCATGAAGCAGCTGACTCAGGAACTTCGCGCGCTCGACCATCTGGCGCAC
GCCGCATCGACCGATCGGGCGCGCCGCGACGAGGCCGCCCGGACTGCGCAGGTGCGCGACGCATTCACACGGGCCTGGAG
CGCCTATGCGCCGACCGTCCGGACGGCGGATGAGCGGAAGCGGGCGCAAGGTCTGTGGGAAGCCTGGCAGCACTTCCTGA
CCGCGGAGGCCGAAGCAGCCGCCCTCGACCGAGCCGGGGAGCGCGATCTCGCCGAGACGGTCCTGATGACAGTGTCGCAG
GCCGACGCGGCGGCCTTCACGCAGACGGCCGACGCGGTGCTGAGCGACCACGAGGCAGGGATCACGGCGCTGATCGATGC
TGTCGAGGCCGCCGGCACGACCTATCGTCTGGCGCTCGCGATCGGCTCGTGGGGCGCCGCCCTCGCTGCCCTGGGGCTGA
TGCGTCTCGCCCTGCGCCGCGTCGCGCACCCGATGACCGCGCTGGCCTCAGCCCTGCAGCGACTGGCCGACAACGACCTC
ACGGTTTCGATCCCTTCGACGTCGCGTCCCGCCGAACTCGGCGTCATGGCGGCCGCGACGAGAGCCGTTCAGGAGACCTT
GCGGCACGCGGGGCGGCGCGACGCGGAGGCTGCTCGGTTGCAAAGTCAGGGCGAGAAGCGCCGCATCGTGGTCGAAGAAG
CGACCGTGCGGGTCGAAAGCGCGATCGCCGGCATCGTCGAGACCGTGAGTTCCAGCGCCGCGGCGCTGCGCGGCACCGCC
GACGGCGTCGGCCGTTCGATCTGCGAGACGGCACGTCGATCGACGATGATGAACGCCCTGCTCGCGCAGACGCGATCGAG
CGTCCGGCGGGTCGCCGACTCCGCCGGCGCGCTCGGCGCGGCGGTCGGCGAGGTCGGCGCGCAGGCGGAGGCCGCCGCAA
CCCTGGCCGAGACAGCCGCGGCGGAGGCGGAGCAGTCGACCGCCCGTGTGCGGGCGCTCAGCGGCGTCGCGGACCGGATC
GGCGACGGAGTCCGCCTCCTCGCGAAGGTAACCGCTCAGACGGATCTTCTAGCGCTCAATGCCACGATCGAGGCCGCGCG
GGCCGGCGACGCGGGCCGCGGCTTCGCCGTGGTCGCTTCCGAAGTGAAGGCCCTGGCCGCGCAGACCAAGGACGCCACCG
ACACCATCGGCCAGCACGTGGCCGAGATCCGCGGCTCCACCGCGGAGGCGGTATTGGCGATCGCGGGCGTCGCGGCGCGG
ATCGAGGGCATGAGCCGCGCGGCGCGTGCCATCGTGGATGCCGTGGCGCGGCAGGGCGCGGCCGCGCGGGAGATCGCGCA
GAGCATCGCGGCGGCGGCCGACGGCACCGACCAGTTGGACACCGACAGCGCGGGCGTCGCCGACACGCCGGAGACGGTCG
ATCCGGCCGCGACCGCCGTGCTCACCGCGGCGGAGAGCCTGACGCAGGACGCCGCGCGTCTCGGCGACGAGATCGCCGGC
ATCTTGGAGAGCCTTCGTGCGGCCTGA

Upstream 100 bases:

>100_bases
TTCGATCTGTCGCGCTGGCGCGTGTAATTGTCGTGAGCGATTGATTTTCTGCGGCTCGTAAAATAGACGCGGTCTCGAGG
TCATGCCTCGGACCGCATCT

Downstream 100 bases:

>100_bases
ATTGTGTAGCGCGGCGAGCGGGACGGAACAGGCCTGATGACATCCTGGACCGTGTGGGTGCGCGGCCGCTTCGCCGGCCG
GTCGCTCCGAAAAGCAGCCC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MVSFPILRDDHYDLGFRTFVIGFTASLLCIPFAFGCVSAFQFGTIDSSSRSLVREIEVVRLLGTMKQLTQELRALDHLAH
AASTDRARRDEAARTAQVRDAFTRAWSAYAPTVRTADERKRAQGLWEAWQHFLTAEAEAAALDRAGERDLAETVLMTVSQ
ADAAAFTQTADAVLSDHEAGITALIDAVEAAGTTYRLALAIGSWGAALAALGLMRLALRRVAHPMTALASALQRLADNDL
TVSIPSTSRPAELGVMAAATRAVQETLRHAGRRDAEAARLQSQGEKRRIVVEEATVRVESAIAGIVETVSSSAAALRGTA
DGVGRSICETARRSTMMNALLAQTRSSVRRVADSAGALGAAVGEVGAQAEAAATLAETAAAEAEQSTARVRALSGVADRI
GDGVRLLAKVTAQTDLLALNATIEAARAGDAGRGFAVVASEVKALAAQTKDATDTIGQHVAEIRGSTAEAVLAIAGVAAR
IEGMSRAARAIVDAVARQGAAAREIAQSIAAAADGTDQLDTDSAGVADTPETVDPAATAVLTAAESLTQDAARLGDEIAG
ILESLRAA

Sequences:

>Translated_568_residues
MVSFPILRDDHYDLGFRTFVIGFTASLLCIPFAFGCVSAFQFGTIDSSSRSLVREIEVVRLLGTMKQLTQELRALDHLAH
AASTDRARRDEAARTAQVRDAFTRAWSAYAPTVRTADERKRAQGLWEAWQHFLTAEAEAAALDRAGERDLAETVLMTVSQ
ADAAAFTQTADAVLSDHEAGITALIDAVEAAGTTYRLALAIGSWGAALAALGLMRLALRRVAHPMTALASALQRLADNDL
TVSIPSTSRPAELGVMAAATRAVQETLRHAGRRDAEAARLQSQGEKRRIVVEEATVRVESAIAGIVETVSSSAAALRGTA
DGVGRSICETARRSTMMNALLAQTRSSVRRVADSAGALGAAVGEVGAQAEAAATLAETAAAEAEQSTARVRALSGVADRI
GDGVRLLAKVTAQTDLLALNATIEAARAGDAGRGFAVVASEVKALAAQTKDATDTIGQHVAEIRGSTAEAVLAIAGVAAR
IEGMSRAARAIVDAVARQGAAAREIAQSIAAAADGTDQLDTDSAGVADTPETVDPAATAVLTAAESLTQDAARLGDEIAG
ILESLRAA
>Mature_568_residues
MVSFPILRDDHYDLGFRTFVIGFTASLLCIPFAFGCVSAFQFGTIDSSSRSLVREIEVVRLLGTMKQLTQELRALDHLAH
AASTDRARRDEAARTAQVRDAFTRAWSAYAPTVRTADERKRAQGLWEAWQHFLTAEAEAAALDRAGERDLAETVLMTVSQ
ADAAAFTQTADAVLSDHEAGITALIDAVEAAGTTYRLALAIGSWGAALAALGLMRLALRRVAHPMTALASALQRLADNDL
TVSIPSTSRPAELGVMAAATRAVQETLRHAGRRDAEAARLQSQGEKRRIVVEEATVRVESAIAGIVETVSSSAAALRGTA
DGVGRSICETARRSTMMNALLAQTRSSVRRVADSAGALGAAVGEVGAQAEAAATLAETAAAEAEQSTARVRALSGVADRI
GDGVRLLAKVTAQTDLLALNATIEAARAGDAGRGFAVVASEVKALAAQTKDATDTIGQHVAEIRGSTAEAVLAIAGVAAR
IEGMSRAARAIVDAVARQGAAAREIAQSIAAAADGTDQLDTDSAGVADTPETVDPAATAVLTAAESLTQDAARLGDEIAG
ILESLRAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=159, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788194, Length=184, Percent_Identity=32.6086956521739, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788195, Length=226, Percent_Identity=28.3185840707965, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787690, Length=221, Percent_Identity=33.4841628959276, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI2367378, Length=304, Percent_Identity=27.3026315789474, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58940; Mature: 58940

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSFPILRDDHYDLGFRTFVIGFTASLLCIPFAFGCVSAFQFGTIDSSSRSLVREIEVVR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LLGTMKQLTQELRALDHLAHAASTDRARRDEAARTAQVRDAFTRAWSAYAPTVRTADERK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RAQGLWEAWQHFLTAEAEAAALDRAGERDLAETVLMTVSQADAAAFTQTADAVLSDHEAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ITALIDAVEAAGTTYRLALAIGSWGAALAALGLMRLALRRVAHPMTALASALQRLADNDL
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVSIPSTSRPAELGVMAAATRAVQETLRHAGRRDAEAARLQSQGEKRRIVVEEATVRVES
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHH
AIAGIVETVSSSAAALRGTADGVGRSICETARRSTMMNALLAQTRSSVRRVADSAGALGA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGEVGAQAEAAATLAETAAAEAEQSTARVRALSGVADRIGDGVRLLAKVTAQTDLLALN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEH
ATIEAARAGDAGRGFAVVASEVKALAAQTKDATDTIGQHVAEIRGSTAEAVLAIAGVAAR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IEGMSRAARAIVDAVARQGAAAREIAQSIAAAADGTDQLDTDSAGVADTPETVDPAATAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LTAAESLTQDAARLGDEIAGILESLRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSFPILRDDHYDLGFRTFVIGFTASLLCIPFAFGCVSAFQFGTIDSSSRSLVREIEVVR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
LLGTMKQLTQELRALDHLAHAASTDRARRDEAARTAQVRDAFTRAWSAYAPTVRTADERK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
RAQGLWEAWQHFLTAEAEAAALDRAGERDLAETVLMTVSQADAAAFTQTADAVLSDHEAG
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
ITALIDAVEAAGTTYRLALAIGSWGAALAALGLMRLALRRVAHPMTALASALQRLADNDL
HHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TVSIPSTSRPAELGVMAAATRAVQETLRHAGRRDAEAARLQSQGEKRRIVVEEATVRVES
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEHHHHHHHHHH
AIAGIVETVSSSAAALRGTADGVGRSICETARRSTMMNALLAQTRSSVRRVADSAGALGA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGEVGAQAEAAATLAETAAAEAEQSTARVRALSGVADRIGDGVRLLAKVTAQTDLLALN
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHEEEH
ATIEAARAGDAGRGFAVVASEVKALAAQTKDATDTIGQHVAEIRGSTAEAVLAIAGVAAR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IEGMSRAARAIVDAVARQGAAAREIAQSIAAAADGTDQLDTDSAGVADTPETVDPAATAV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHH
LTAAESLTQDAARLGDEIAGILESLRAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA