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The map label for this gene is waaA [H]

Identifier: 170026356

GI number: 170026356

Start: 4582268

End: 4583587

Strand: Direct

Name: waaA [H]

Synonym: YPK_4149

Alternate gene names: 170026356

Gene position: 4582268-4583587 (Clockwise)

Preceding gene: 170026355

Following gene: 170026357

Centisome position: 97.71

GC content: 49.47

Gene sequence:

>1320_bases
ATGGTATTATTCTTAATAATCCATATAAATGAAATTGATAGAATGCTGCTGCGTTTATACCAGGTATTACTCTACCTTAT
TCAACCTCTGATTTGGCTGCGTTTACTATTACGTAGCCGTAAAGCCCCCGCTTATCGCAAGCGTTGGGGGGAACGCTATG
GTTTTTGTGCCGGTAAAGTCGTTGCTGGCGGTATCATGCTGCATTCCGTTTCAGTCGGGGAAACACTGGCTGCAATCCCA
TTGGTCAGAGCATTACGCCACCGTTACCCGTCGCTGCCTATCACGGTGACCACGATGACGCCTACCGGCTCAGAGCGCGT
CCAGTCTGCTTTTGGTAAAGATGTTCACCACGTTTATTTACCTTATGATCTCCCCGGCTCTGTGAACCGTTTCCTTGACC
AGGTCAATCCCAAACTGGTTATCATCATGGAAACTGAACTTTGGCCTAACCTGATCAACACTCTGCATCGCCGTAAGATC
CCACTGGTTATTGCCAATGCACGTCTTTCTGCCCGCTCTGCGGCAGGTTACAAGAAGATCGGTAGTTTTATCCGCACTAT
ACTGCAACGGATCACGTTGATTGCGGCACAGAACCAAGAGGATGGTGACCGCTTCATCGAACTGGGGCTTAAACGTTCCC
AGCTCACCGTGACGGGTAGTCTGAAGTTTGATATTTCTGTCACACCGGAGTTGGCAGCCAGAGCGGTGACATTACGCCGC
CAATGGGCACCGCACCGCCCCGTTTGGATTGCGACTAGCACACATGACGGTGAAGAAACTATCTTGTTGGAAGCCCATCG
GCAGCTATTACAACAGTTCCCAACATTGCTACTGATCCTGGTACCTCGCCATCCTGAACGCTTCGGAAAGGCCGTTGAAT
TAACACAAAAGATAGGCTTGAGTTATACATTACGTAGTAAAGGTGAAGTGCCCTCGAGTAGCACCCAAGTCGTTATCGGC
GACACGATGGGTGAGCTGATGCTGCTGTACGGTATTGCCGACCTGGCCTTTGTTGGCGGTAGTTTGGTTGAACGTGGCGG
TCATAACCCACTGGAAGCAGCGGCTCATGCTATTCCCGTGTTGATGGGCCCACATACCTTTAACTTTAAAGATATTTGCG
CCAAGCTGGAGCAGGCTGAAGGGTTAATTACCGTGACTGATACTCTATCGCTGGTAAAAGAAATCACGGTGTTACTGACT
GATGAAGATTGCCGCCTCTACTATGGCCGCCACGCGGTTGATGTCTTACATGAAAATCAGGGCGCATTACAACGGTTATT
ACATTTGTTGGAGCCTTATCTGCCACAACGGAGCCACTAA

Upstream 100 bases:

>100_bases
TTTATCACTCAGAGCAAGATATTATATTCTTCCTATGAATAACCACGGCTCAATGTGGTGCTCCGCCCTCCTAGCCGGAA
AGAGCCTTTTTTGCCCAGAT

Downstream 100 bases:

>100_bases
ATGGGTACCAAAAAACGTCTGTCGGTGGTGATGATAACCAAGAATGAAGCCTCTCTGCTGACGGACTGTTTAGCATCCGT
GGCCTGGGCTGATGAAATAA

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MVLFLIIHINEIDRMLLRLYQVLLYLIQPLIWLRLLLRSRKAPAYRKRWGERYGFCAGKVVAGGIMLHSVSVGETLAAIP
LVRALRHRYPSLPITVTTMTPTGSERVQSAFGKDVHHVYLPYDLPGSVNRFLDQVNPKLVIIMETELWPNLINTLHRRKI
PLVIANARLSARSAAGYKKIGSFIRTILQRITLIAAQNQEDGDRFIELGLKRSQLTVTGSLKFDISVTPELAARAVTLRR
QWAPHRPVWIATSTHDGEETILLEAHRQLLQQFPTLLLILVPRHPERFGKAVELTQKIGLSYTLRSKGEVPSSSTQVVIG
DTMGELMLLYGIADLAFVGGSLVERGGHNPLEAAAHAIPVLMGPHTFNFKDICAKLEQAEGLITVTDTLSLVKEITVLLT
DEDCRLYYGRHAVDVLHENQGALQRLLHLLEPYLPQRSH

Sequences:

>Translated_439_residues
MVLFLIIHINEIDRMLLRLYQVLLYLIQPLIWLRLLLRSRKAPAYRKRWGERYGFCAGKVVAGGIMLHSVSVGETLAAIP
LVRALRHRYPSLPITVTTMTPTGSERVQSAFGKDVHHVYLPYDLPGSVNRFLDQVNPKLVIIMETELWPNLINTLHRRKI
PLVIANARLSARSAAGYKKIGSFIRTILQRITLIAAQNQEDGDRFIELGLKRSQLTVTGSLKFDISVTPELAARAVTLRR
QWAPHRPVWIATSTHDGEETILLEAHRQLLQQFPTLLLILVPRHPERFGKAVELTQKIGLSYTLRSKGEVPSSSTQVVIG
DTMGELMLLYGIADLAFVGGSLVERGGHNPLEAAAHAIPVLMGPHTFNFKDICAKLEQAEGLITVTDTLSLVKEITVLLT
DEDCRLYYGRHAVDVLHENQGALQRLLHLLEPYLPQRSH
>Mature_439_residues
MVLFLIIHINEIDRMLLRLYQVLLYLIQPLIWLRLLLRSRKAPAYRKRWGERYGFCAGKVVAGGIMLHSVSVGETLAAIP
LVRALRHRYPSLPITVTTMTPTGSERVQSAFGKDVHHVYLPYDLPGSVNRFLDQVNPKLVIIMETELWPNLINTLHRRKI
PLVIANARLSARSAAGYKKIGSFIRTILQRITLIAAQNQEDGDRFIELGLKRSQLTVTGSLKFDISVTPELAARAVTLRR
QWAPHRPVWIATSTHDGEETILLEAHRQLLQQFPTLLLILVPRHPERFGKAVELTQKIGLSYTLRSKGEVPSSSTQVVIG
DTMGELMLLYGIADLAFVGGSLVERGGHNPLEAAAHAIPVLMGPHTFNFKDICAKLEQAEGLITVTDTLSLVKEITVLLT
DEDCRLYYGRHAVDVLHENQGALQRLLHLLEPYLPQRSH

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers two molecules of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=425, Percent_Identity=79.7647058823529, Blast_Score=708, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 49333; Mature: 49333

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFLIIHINEIDRMLLRLYQVLLYLIQPLIWLRLLLRSRKAPAYRKRWGERYGFCAGKV
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHCCCCHHHH
VAGGIMLHSVSVGETLAAIPLVRALRHRYPSLPITVTTMTPTGSERVQSAFGKDVHHVYL
HHCHHEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEE
PYDLPGSVNRFLDQVNPKLVIIMETELWPNLINTLHRRKIPLVIANARLSARSAAGYKKI
CCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCHHHHCCHHHH
GSFIRTILQRITLIAAQNQEDGDRFIELGLKRSQLTVTGSLKFDISVTPELAARAVTLRR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEEEEEEEECHHHHHHHHHHHH
QWAPHRPVWIATSTHDGEETILLEAHRQLLQQFPTLLLILVPRHPERFGKAVELTQKIGL
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCC
SYTLRSKGEVPSSSTQVVIGDTMGELMLLYGIADLAFVGGSLVERGGHNPLEAAAHAIPV
EEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHE
LMGPHTFNFKDICAKLEQAEGLITVTDTLSLVKEITVLLTDEDCRLYYGRHAVDVLHENQ
EECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHEEEEECCCCEEEECCHHHHHHHCCH
GALQRLLHLLEPYLPQRSH
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVLFLIIHINEIDRMLLRLYQVLLYLIQPLIWLRLLLRSRKAPAYRKRWGERYGFCAGKV
CEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHCCCCHHHH
VAGGIMLHSVSVGETLAAIPLVRALRHRYPSLPITVTTMTPTGSERVQSAFGKDVHHVYL
HHCHHEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCEEEEE
PYDLPGSVNRFLDQVNPKLVIIMETELWPNLINTLHRRKIPLVIANARLSARSAAGYKKI
CCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCCHHHHCCHHHH
GSFIRTILQRITLIAAQNQEDGDRFIELGLKRSQLTVTGSLKFDISVTPELAARAVTLRR
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEEEEEEEEECHHHHHHHHHHHH
QWAPHRPVWIATSTHDGEETILLEAHRQLLQQFPTLLLILVPRHPERFGKAVELTQKIGL
HCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCC
SYTLRSKGEVPSSSTQVVIGDTMGELMLLYGIADLAFVGGSLVERGGHNPLEAAAHAIPV
EEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHE
LMGPHTFNFKDICAKLEQAEGLITVTDTLSLVKEITVLLTDEDCRLYYGRHAVDVLHENQ
EECCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHEEEEECCCCEEEECCHHHHHHHCCH
GALQRLLHLLEPYLPQRSH
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]