Click here to switch to the map view.

The map label for this gene is rfaC [H]

Identifier: 170026355

GI number: 170026355

Start: 4580925

End: 4581890

Strand: Direct

Name: rfaC [H]

Synonym: YPK_4148

Alternate gene names: 170026355

Gene position: 4580925-4581890 (Clockwise)

Preceding gene: 170026354

Following gene: 170026356

Centisome position: 97.69

GC content: 50.72

Gene sequence:

>966_bases
ATGCACGTATTAATCGTTAAAACCTCGTCAATGGGCGATGTTTTACATACCTTACCCGCGCTGACGGATGCCATGAATGC
CATACCCGGTATTCGCTTCGATTGGGTGGTAGAAGAAGGGTTCAGCCAAATCCCCAGTTGGCATCCGGCGGTGGATAAAG
TGATCCCGGTGGCCATCCGCCGTTGGCGTAAAAACTGGTTTGGTAGTGATACCCGGCAGGAACGCTGTGATTTTAAGCGT
GTGGTACAACAACGCAGTTATGATCGGGTCATTGATGCCCAAGGGTTGATTAAAAGCGCCGCGCTGATAACCCGGATTGC
GAAAGGCACGAAGCACGGGCCGGATTGTAAAAGTGCCCGTGAGCCGTTTGCCAGTTGGTTTTATAACTGCCGCCATGAAA
TTGATACCAAACAACATGCCGTAGAACGTATACGTCAACTGTTTGCTAAAAGCCTCGGCTATGATAAACCGGAAAGTTAT
GGCGACTATGCCATCGCACAACGCTTTTTAAATCAGTTACCGGCCGATGCAGGTCAGTACTTGGTTTTCCTACATGCGAC
GACCCGTGACAACAAGCACTGGCCCGAGAGCCATTGGGTACAATTGATTGAGTTAGTGCAACCCACAGGTTTAAAAATCA
AACTACCGTGGGGCGCAGAACATGAGCATCAGCGCGCTTTACGATTAGCGGAACATTTCCCACACGTAGAGGTTCTGCCT
AAGCTCAGTCTTCAGCAGGTCGCCGAGGTTCTGGCGGGTGCAAAAGCCGTAGTCTCTGTCGATACTGGCCTCAGCCATCT
GACCGCCGCCCTGGATCGCCCAAACATTACGCTGTTTGGCCCCACTGACCCCGGTTTAATCGGCGGCTACGGGAAAAACC
AAATTGCCGTGATTTCCGAGCAAAAAAAGATGGATAGCCTCTCTGCGCCCACTATTATGGCACGATTAGAAACACTCATT
TCATAG

Upstream 100 bases:

>100_bases
GCTATCATCAAAGTTTGATTGATATCCAACCCGAACACGTGATGGCCGCGCTTGAGAAGCAATTGGCTACGCAAGAATGC
TCAGTCAAAGGGGGCGATTA

Downstream 100 bases:

>100_bases
CGCTGCTTTATTGTCTCTGAAAGAGTGAGTTCATAAACATCCGATATAAAACTTTCATCGATTCTGGTAATTATCAGGGT
CGATGAAATTGAGAAATATT

Product: ADP-heptose:LPS heptosyl transferase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MHVLIVKTSSMGDVLHTLPALTDAMNAIPGIRFDWVVEEGFSQIPSWHPAVDKVIPVAIRRWRKNWFGSDTRQERCDFKR
VVQQRSYDRVIDAQGLIKSAALITRIAKGTKHGPDCKSAREPFASWFYNCRHEIDTKQHAVERIRQLFAKSLGYDKPESY
GDYAIAQRFLNQLPADAGQYLVFLHATTRDNKHWPESHWVQLIELVQPTGLKIKLPWGAEHEHQRALRLAEHFPHVEVLP
KLSLQQVAEVLAGAKAVVSVDTGLSHLTAALDRPNITLFGPTDPGLIGGYGKNQIAVISEQKKMDSLSAPTIMARLETLI
S

Sequences:

>Translated_321_residues
MHVLIVKTSSMGDVLHTLPALTDAMNAIPGIRFDWVVEEGFSQIPSWHPAVDKVIPVAIRRWRKNWFGSDTRQERCDFKR
VVQQRSYDRVIDAQGLIKSAALITRIAKGTKHGPDCKSAREPFASWFYNCRHEIDTKQHAVERIRQLFAKSLGYDKPESY
GDYAIAQRFLNQLPADAGQYLVFLHATTRDNKHWPESHWVQLIELVQPTGLKIKLPWGAEHEHQRALRLAEHFPHVEVLP
KLSLQQVAEVLAGAKAVVSVDTGLSHLTAALDRPNITLFGPTDPGLIGGYGKNQIAVISEQKKMDSLSAPTIMARLETLI
S
>Mature_321_residues
MHVLIVKTSSMGDVLHTLPALTDAMNAIPGIRFDWVVEEGFSQIPSWHPAVDKVIPVAIRRWRKNWFGSDTRQERCDFKR
VVQQRSYDRVIDAQGLIKSAALITRIAKGTKHGPDCKSAREPFASWFYNCRHEIDTKQHAVERIRQLFAKSLGYDKPESY
GDYAIAQRFLNQLPADAGQYLVFLHATTRDNKHWPESHWVQLIELVQPTGLKIKLPWGAEHEHQRALRLAEHFPHVEVLP
KLSLQQVAEVLAGAKAVVSVDTGLSHLTAALDRPNITLFGPTDPGLIGGYGKNQIAVISEQKKMDSLSAPTIMARLETLI
S

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=319, Percent_Identity=68.3385579937304, Blast_Score=461, Evalue=1e-131,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 36116; Mature: 36116

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVLIVKTSSMGDVLHTLPALTDAMNAIPGIRFDWVVEEGFSQIPSWHPAVDKVIPVAIR
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHH
RWRKNWFGSDTRQERCDFKRVVQQRSYDRVIDAQGLIKSAALITRIAKGTKHGPDCKSAR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
EPFASWFYNCRHEIDTKQHAVERIRQLFAKSLGYDKPESYGDYAIAQRFLNQLPADAGQY
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
LVFLHATTRDNKHWPESHWVQLIELVQPTGLKIKLPWGAEHEHQRALRLAEHFPHVEVLP
EEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHH
KLSLQQVAEVLAGAKAVVSVDTGLSHLTAALDRPNITLFGPTDPGLIGGYGKNQIAVISE
CCCHHHHHHHHCCCHHEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEC
QKKMDSLSAPTIMARLETLIS
HHHHHHCCCHHHHHHHHHHHC
>Mature Secondary Structure
MHVLIVKTSSMGDVLHTLPALTDAMNAIPGIRFDWVVEEGFSQIPSWHPAVDKVIPVAIR
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCHHHHHHHHHHHH
RWRKNWFGSDTRQERCDFKRVVQQRSYDRVIDAQGLIKSAALITRIAKGTKHGPDCKSAR
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
EPFASWFYNCRHEIDTKQHAVERIRQLFAKSLGYDKPESYGDYAIAQRFLNQLPADAGQY
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
LVFLHATTRDNKHWPESHWVQLIELVQPTGLKIKLPWGAEHEHQRALRLAEHFPHVEVLP
EEEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHCCCHHHHH
KLSLQQVAEVLAGAKAVVSVDTGLSHLTAALDRPNITLFGPTDPGLIGGYGKNQIAVISE
CCCHHHHHHHHCCCHHEEEECCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEEEEC
QKKMDSLSAPTIMARLETLIS
HHHHHHCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8478319; 8041620; 9278503; 1624462 [H]