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The map label for this gene is qorA [H]

Identifier: 170026069

GI number: 170026069

Start: 4248397

End: 4249380

Strand: Direct

Name: qorA [H]

Synonym: YPK_3856

Alternate gene names: 170026069

Gene position: 4248397-4249380 (Clockwise)

Preceding gene: 170026064

Following gene: 170026072

Centisome position: 90.59

GC content: 54.07

Gene sequence:

>984_bases
ATGGCAAAGCATATTCAATTTACCACCACGGGTGGACCAGATGTATTGCAATATCTTGAATTCACCCCCTCAGACCCCGC
CCCCCATGAAGTCCAGGTCGAAAATAAAGCTATCGGTATCAATTATATCGATACTTATGTCCGCAGCGGGCTTTATCCTC
CTGCCCATTTGCCCAGTGGTTTAGGTACAGAAGCGGCCGGTATCGTCAGTAAAGTGGGGGCGGCGGTCAGTTCCGTGAAG
GTCGGTGATCGGGTGGTGTATGCCCAATCCGCTCTCGGTGCTTACAGCGAAGTGCATAATGTTCCAGCGGATAAAATCGC
CTTACTGCCGGAGCAGATCTCTTTTGAACAAGCGGCAGCCTCGTTTTTAAAAGGGCTGACTGCCTATTATTTGTTGCGCC
AGACCCACGAGATTAAACCGGGGGAAGTGTTCCTGTTCCACGCTGCGGCGGGAGGGGTTGGGCTGATTGCCTGCCAATGG
GCCAAAGCACTGGGTGCCAAATTGATCGGCACGGTGGGATCCGATGAGAAAGCCCAATTGGCCAAAGCGGCCGGGGCTTG
GGCGACCATCAACTATCGGACAGAAAATATTGCTCAGCGGGTGGCCGAGCTAACCGAGGGTGAGAAAGTAGGCGTCGTGT
ATGACTCGGTTGGGAAAAGCACTTGGGAAGCCTCGCTTGATAGCTTAAAGCGCCGGGGCCTGCTGGTTAGCTTTGGTAAT
GCCTCTGGGCCGGTAACGGGTGTCAACCTCGGGATTCTAAACCAAAAAGGGGGGATCTATGTCACCCGCCCTTCACTGAA
TGTCTATGTCGCCAACCGGCAAGAACTGGAAAGCGCCAGCCAGCAACTCTTTTCAATGATTACCAGTGGGGCGATTAATG
TGGATGTTGCTCAAGCGCAGCAATTCCCGCTATGTGACGCACAACGCGCCCATGAAACACTCGAGGGCCGCCAGACGACA
GGCTCCAGCTTGCTGATCCCGTAA

Upstream 100 bases:

>100_bases
GCACAAATCCCGATAAGCTGATATCCGTCAGTGAGTCAGGTAAGTGAACAGAGCGGCCCTTGTAACCTCAAGTAAGAAGG
CTATACCTCGAGGAACTGAC

Downstream 100 bases:

>100_bases
GTTTAGATGATTGAAAATGAGTTTACATGATTGAAAAACAGAGGGCCCCGATTAAGGAGCCCTCTGTCATTACACTTTCT
TTGATGCATATGTAGGGGTA

Product: quinone oxidoreductase, NADPH-dependent

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSGLGTEAAGIVSKVGAAVSSVK
VGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAASFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQW
AKALGAKLIGTVGSDEKAQLAKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
ASGPVTGVNLGILNQKGGIYVTRPSLNVYVANRQELESASQQLFSMITSGAINVDVAQAQQFPLCDAQRAHETLEGRQTT
GSSLLIP

Sequences:

>Translated_327_residues
MAKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSGLGTEAAGIVSKVGAAVSSVK
VGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAASFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQW
AKALGAKLIGTVGSDEKAQLAKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
ASGPVTGVNLGILNQKGGIYVTRPSLNVYVANRQELESASQQLFSMITSGAINVDVAQAQQFPLCDAQRAHETLEGRQTT
GSSLLIP
>Mature_326_residues
AKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSGLGTEAAGIVSKVGAAVSSVKV
GDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAASFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQWA
KALGAKLIGTVGSDEKAQLAKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGNA
SGPVTGVNLGILNQKGGIYVTRPSLNVYVANRQELESASQQLFSMITSGAINVDVAQAQQFPLCDAQRAHETLEGRQTTG
SSLLIP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=27.6595744680851, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=27.6595744680851, Blast_Score=128, Evalue=9e-30,
Organism=Homo sapiens, GI194239676, Length=203, Percent_Identity=34.9753694581281, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI22538446, Length=329, Percent_Identity=30.3951367781155, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI22538444, Length=329, Percent_Identity=30.3951367781155, Blast_Score=118, Evalue=7e-27,
Organism=Homo sapiens, GI18379349, Length=312, Percent_Identity=29.8076923076923, Blast_Score=111, Evalue=9e-25,
Organism=Homo sapiens, GI28557745, Length=308, Percent_Identity=30.1948051948052, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI24308257, Length=239, Percent_Identity=28.8702928870293, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI47519420, Length=244, Percent_Identity=27.8688524590164, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=73.394495412844, Blast_Score=496, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17507255, Length=258, Percent_Identity=32.5581395348837, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17536829, Length=174, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562584, Length=324, Percent_Identity=24.3827160493827, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=330, Percent_Identity=37.2727272727273, Blast_Score=195, Evalue=8e-51,
Organism=Saccharomyces cerevisiae, GI6319621, Length=266, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=253, Percent_Identity=26.8774703557312, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=293, Percent_Identity=26.2798634812287, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=270, Percent_Identity=25.5555555555556, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45550423, Length=304, Percent_Identity=26.9736842105263, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34640; Mature: 34508

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSG
CCCEEEEEECCCHHHHHHHHCCCCCCCCCEEEECCCEEEHHHHHHHHHCCCCCCCCCCCC
LGTEAAGIVSKVGAAVSSVKVGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAA
CCCHHHHHHHHHHHHHHHEECCCEEEEEHHHHHHHHHHHCCCHHHEECCHHHHHHHHHHH
SFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQWAKALGAKLIGTVGSDEKAQL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCHHHHH
AKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
HHHCCCEEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEECC
ASGPVTGVNLGILNQKGGIYVTRPSLNVYVANRQELESASQQLFSMITSGAINVDVAQAQ
CCCCEEEEEEEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEHHHHC
QFPLCDAQRAHETLEGRQTTGSSLLIP
CCCCCCHHHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure 
AKHIQFTTTGGPDVLQYLEFTPSDPAPHEVQVENKAIGINYIDTYVRSGLYPPAHLPSG
CCEEEEEECCCHHHHHHHHCCCCCCCCCEEEECCCEEEHHHHHHHHHCCCCCCCCCCCC
LGTEAAGIVSKVGAAVSSVKVGDRVVYAQSALGAYSEVHNVPADKIALLPEQISFEQAAA
CCCHHHHHHHHHHHHHHHEECCCEEEEEHHHHHHHHHHHCCCHHHEECCHHHHHHHHHHH
SFLKGLTAYYLLRQTHEIKPGEVFLFHAAAGGVGLIACQWAKALGAKLIGTVGSDEKAQL
HHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHEECCCCCHHHHH
AKAAGAWATINYRTENIAQRVAELTEGEKVGVVYDSVGKSTWEASLDSLKRRGLLVSFGN
HHHCCCEEEEEECHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCEEEEECC
ASGPVTGVNLGILNQKGGIYVTRPSLNVYVANRQELESASQQLFSMITSGAINVDVAQAQ
CCCCEEEEEEEEEECCCCEEEECCCEEEEECCHHHHHHHHHHHHHHHHCCCCEEEHHHHC
QFPLCDAQRAHETLEGRQTTGSSLLIP
CCCCCCHHHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]