Click here to switch to the map view.

The map label for this gene is zur [H]

Identifier: 170026072

GI number: 170026072

Start: 4251748

End: 4252260

Strand: Direct

Name: zur [H]

Synonym: YPK_3859

Alternate gene names: 170026072

Gene position: 4251748-4252260 (Clockwise)

Preceding gene: 170026069

Following gene: 170026075

Centisome position: 90.67

GC content: 48.34

Gene sequence:

>513_bases
ATGATGAACCCTATCAATCAGGAAAAGCTGCTCGCACAAGCTGAAAGCCTGTGCCAACAACGAAACGTCCGGCTGACCCC
GCAACGTCTTGAAGTATTACGTCTAATGGCGCAACAGCCCGGTGCAATTAGCGCTTATGATCTGCTGGATCTACTACGAG
TCGCTGAGCCACAAGCCAAACCGCCTACCGTTTATCGCGCACTGGATTTTTTATTGGAGCAAGGGTTTATTCACCGTGTT
GAATCAGCCAATAGCTATGTTCTCTGCCACCACTTTGAAGAACCCACGCATACTTCTGCCTTGTTTATCTGTGATCGCTG
CAAGATTGTGACAGAACGCCCTACCGTTGGTATTGAAGAGGCATTGGCACAGTTAGCAAAACAGTCAGGTTTTACACTGC
GCCATAGCGTGGTGGAAGCACACGGTTTATGTACTGAATGTGGGGTAGTTGAAGCCTGCGAAAGCCACGATGATTGTGAG
CATGACCACTCCATCGTCGTTAAAAAGAAGTAA

Upstream 100 bases:

>100_bases
TGTAAAATTGTGATCTCATAGCGCCATTTCCCTCCCCCCTATCGGCGATTACAGGTAAACATGATAAAATCACGTTCAAT
TCTAAAGCTGCGGGATGAAT

Downstream 100 bases:

>100_bases
TATCTTGATTAATAAGAAGTCGTATCGTGATTAAGATGAGATAGAACAGCAAAAAGCAAAAAGCAAAAAGCAAAAAGCAA
AAAGCAAAAAGCAAAAAGCA

Product: zinc uptake transcriptional repressor

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MMNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAKPPTVYRALDFLLEQGFIHRV
ESANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEEALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCE
HDHSIVVKKK

Sequences:

>Translated_170_residues
MMNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAKPPTVYRALDFLLEQGFIHRV
ESANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEEALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCE
HDHSIVVKKK
>Mature_170_residues
MMNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAKPPTVYRALDFLLEQGFIHRV
ESANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEEALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCE
HDHSIVVKKK

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=169, Percent_Identity=69.2307692307692, Blast_Score=243, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 19114; Mature: 19114

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAK
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PPTVYRALDFLLEQGFIHRVESANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEE
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCCCHHH
ALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCEHDHSIVVKKK
HHHHHHHHCCCHHHHHHHHHHCCHHHCCHHHHHHCCCCCCCCCCEEEECC
>Mature Secondary Structure
MMNPINQEKLLAQAESLCQQRNVRLTPQRLEVLRLMAQQPGAISAYDLLDLLRVAEPQAK
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCC
PPTVYRALDFLLEQGFIHRVESANSYVLCHHFEEPTHTSALFICDRCKIVTERPTVGIEE
CCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCEEEECCCCCCHHH
ALAQLAKQSGFTLRHSVVEAHGLCTECGVVEACESHDDCEHDHSIVVKKK
HHHHHHHHCCCHHHHHHHHHHCCHHHCCHHHHHHCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]