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The map label for this gene is yadA [H]

Identifier: 170024898

GI number: 170024898

Start: 2944132

End: 2945226

Strand: Reverse

Name: yadA [H]

Synonym: YPK_2673

Alternate gene names: 170024898

Gene position: 2945226-2944132 (Counterclockwise)

Preceding gene: 170024899

Following gene: 170024897

Centisome position: 62.81

GC content: 40.46

Gene sequence:

>1095_bases
ATGTTTACAAAACGTAATTTCAAAAAATCGGTTGTTATCATCACGGCAATTTTTTCTGGGTCTGTGTTCGCGGATGTCAA
TATTGGTGATTTAAATACGGGGGTTATTGGCAATGGAACTGCGGTAGGGAATAATAACTCGCTTGGCGGTTCGACAAATG
GTGTCGTTGTTGGCAACGGTGGCAGCTTATCCAACTCGACAAATGGCGTTGTCATTGGGAATGGCAGTGTTAGTGATGGG
GATGGAGTATCGATAGGTGGCGGCACGTCAACGAATGGCGGAATTGCGATTGGTAGCGGCTCCAATGCAACACAATCTGA
TGAAATAAACATCGGTGATCGCCAGATAACCGGTGTTAAAGCGGGTGTTGCAGATACCGATGCGGCGAATGTCGGTCAAC
TGGTTGCTAAAGCTGGCGAGACACTTAATAGCGCTAATATATATGTGGATAACCAAGCGACCGAAACACTTAATAATGCG
AATCTATACACAGATAACAAAGCGACTGAAACAATTAATAATGCCAATACATACACGGATAACAAATCATCCGAAACGCT
AAATTCAGCAAATAGCTATACTGATAATAAATCATCTGAAACATTGAATAGTGCAAATACTTATACTGACAGCAAAACTG
CTGAGATATTTAATACAAATAAAACATACATGGACGAGAAGTCGAAAGAAACGCTAAATAACACCTATGACTATGTAGAT
AGTAAAGTTTCATCAATTGTTTATGATGTAAATAGCTATACAGATAAGACGGTAAATACAGCGTTTGAAACCTCATTATC
CGATGCTAAAAGTTATGTTGATGATAAATACAATCAACTTAGTGATAAAGTTAACAAGAATTTCAATAAGACTAATGCAG
GTATTTCTGGTGCAATGGCGATGTCAGGTATTCCTCAAAAATTCGGATATGAAAAATCGTTTGGGATGGCGATAGGGGCT
TATCGCGGGCAAAGTGCACTCGCTGTGGGAGGCGACTGGAACATCAATCATAAAACGATAACGCGAGTCAATGTTTCTGC
CGACACTGAAGGCGGTGTCGGTGTTGCAGCGGGTTTTGCTTTTGGCATTAATTAA

Upstream 100 bases:

>100_bases
GTTGTAATGGAATGGACGCCCCATTGATTCGGTATCAATGTATCAAAATATAATGGGGTGAAAATAATGCAAATTCTAAT
AGCATTTATGGATATTAAAC

Downstream 100 bases:

>100_bases
TGAATAAGGAAATTAAACGGATGCAACGGATGCAATGCATATATATCGCCACTTGGTTAATCGCAGTATTTATCTCGCCG
ATAGCGATAGCTAACAATAC

Product: hemagluttinin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MFTKRNFKKSVVIITAIFSGSVFADVNIGDLNTGVIGNGTAVGNNNSLGGSTNGVVVGNGGSLSNSTNGVVIGNGSVSDG
DGVSIGGGTSTNGGIAIGSGSNATQSDEINIGDRQITGVKAGVADTDAANVGQLVAKAGETLNSANIYVDNQATETLNNA
NLYTDNKATETINNANTYTDNKSSETLNSANSYTDNKSSETLNSANTYTDSKTAEIFNTNKTYMDEKSKETLNNTYDYVD
SKVSSIVYDVNSYTDKTVNTAFETSLSDAKSYVDDKYNQLSDKVNKNFNKTNAGISGAMAMSGIPQKFGYEKSFGMAIGA
YRGQSALAVGGDWNINHKTITRVNVSADTEGGVGVAAGFAFGIN

Sequences:

>Translated_364_residues
MFTKRNFKKSVVIITAIFSGSVFADVNIGDLNTGVIGNGTAVGNNNSLGGSTNGVVVGNGGSLSNSTNGVVIGNGSVSDG
DGVSIGGGTSTNGGIAIGSGSNATQSDEINIGDRQITGVKAGVADTDAANVGQLVAKAGETLNSANIYVDNQATETLNNA
NLYTDNKATETINNANTYTDNKSSETLNSANSYTDNKSSETLNSANTYTDSKTAEIFNTNKTYMDEKSKETLNNTYDYVD
SKVSSIVYDVNSYTDKTVNTAFETSLSDAKSYVDDKYNQLSDKVNKNFNKTNAGISGAMAMSGIPQKFGYEKSFGMAIGA
YRGQSALAVGGDWNINHKTITRVNVSADTEGGVGVAAGFAFGIN
>Mature_364_residues
MFTKRNFKKSVVIITAIFSGSVFADVNIGDLNTGVIGNGTAVGNNNSLGGSTNGVVVGNGGSLSNSTNGVVIGNGSVSDG
DGVSIGGGTSTNGGIAIGSGSNATQSDEINIGDRQITGVKAGVADTDAANVGQLVAKAGETLNSANIYVDNQATETLNNA
NLYTDNKATETINNANTYTDNKSSETLNSANSYTDNKSSETLNSANTYTDSKTAEIFNTNKTYMDEKSKETLNNTYDYVD
SKVSSIVYDVNSYTDKTVNTAFETSLSDAKSYVDDKYNQLSDKVNKNFNKTNAGISGAMAMSGIPQKFGYEKSFGMAIGA
YRGQSALAVGGDWNINHKTITRVNVSADTEGGVGVAAGFAFGIN

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 37726; Mature: 37726

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTKRNFKKSVVIITAIFSGSVFADVNIGDLNTGVIGNGTAVGNNNSLGGSTNGVVVGNG
CCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCEECCCEEECCCCCCCCCCCCEEEECC
GSLSNSTNGVVIGNGSVSDGDGVSIGGGTSTNGGIAIGSGSNATQSDEINIGDRQITGVK
CCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEE
AGVADTDAANVGQLVAKAGETLNSANIYVDNQATETLNNANLYTDNKATETINNANTYTD
CCCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCCEEECCCHHHHCCCCCCCCC
NKSSETLNSANSYTDNKSSETLNSANTYTDSKTAEIFNTNKTYMDEKSKETLNNTYDYVD
CCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHH
SKVSSIVYDVNSYTDKTVNTAFETSLSDAKSYVDDKYNQLSDKVNKNFNKTNAGISGAMA
HHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
MSGIPQKFGYEKSFGMAIGAYRGQSALAVGGDWNINHKTITRVNVSADTEGGVGVAAGFA
HCCCCHHHCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEECCCCCCCCEEEEEEE
FGIN
ECCC
>Mature Secondary Structure
MFTKRNFKKSVVIITAIFSGSVFADVNIGDLNTGVIGNGTAVGNNNSLGGSTNGVVVGNG
CCCCCCCCCEEEEEEEEECCCEEEEEECCCCCCCEECCCEEECCCCCCCCCCCCEEEECC
GSLSNSTNGVVIGNGSVSDGDGVSIGGGTSTNGGIAIGSGSNATQSDEINIGDRQITGVK
CCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEE
AGVADTDAANVGQLVAKAGETLNSANIYVDNQATETLNNANLYTDNKATETINNANTYTD
CCCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCCEEECCCHHHHCCCCCCCCC
NKSSETLNSANSYTDNKSSETLNSANTYTDSKTAEIFNTNKTYMDEKSKETLNNTYDYVD
CCCHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHHHHH
SKVSSIVYDVNSYTDKTVNTAFETSLSDAKSYVDDKYNQLSDKVNKNFNKTNAGISGAMA
HHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
MSGIPQKFGYEKSFGMAIGAYRGQSALAVGGDWNINHKTITRVNVSADTEGGVGVAAGFA
HCCCCHHHCCCCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEECCCCCCCCEEEEEEE
FGIN
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2761389; 7934875; 2592347; 1548243 [H]