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The map label for this gene is nudL

Identifier: 170024675

GI number: 170024675

Start: 2682356

End: 2682955

Strand: Direct

Name: nudL

Synonym: YPK_2450

Alternate gene names: 170024675

Gene position: 2682356-2682955 (Clockwise)

Preceding gene: 170024674

Following gene: 170024676

Centisome position: 57.2

GC content: 50.17

Gene sequence:

>600_bases
GTGAGTGAATTAATTACTGGGCAGTACTTGTCCGAGTTTATTAACCGTTTCCAACTACAACTGCCGCAACCCGATAACGT
TTTGACTCATAGTCACTATTTTTCTGCCACTAACCGCCGTGCTGCTGTATTGATACCCATTATTTGCCGCCCAGAGCCCA
CATTATTACTGACCCGCCGCGCTGATCACTTGCGTAAACACGCGGGTCAGGTCGCGTTCCCGGGTGGGAAGGCCGATCCT
GACGATCAGTCACTGATTAGTACCGCGCTACGTGAAGCCGAAGAGGAAGTCGCCATTCCGGCATCCGTAGTTCATGTGTT
AGGGAAACTGGCTCCCCTGAACAGTTCTAGTGGTTATCACGTCACGCCAATTGTGGGATTAGTACCAGCCAATATCCCTT
TTTACGGCAATGACGAAGAAGTGGCTGGGCTATTTGAAATCCCCTTACATGAAGCGCTGAGCCTCTCTCGCTACCATTCG
CTGGATATTCATCGGGAGGGAATCAATCACCGGGTCTATCTTTCATGGTACGAAAACCAATTTATCTGGGGCCTGACCGC
CACGATTATTCGCCATCTGGCGCAGCAAGTCAGTATTTGA

Upstream 100 bases:

>100_bases
GAGGGGGGATTGTCGCCGACAGCCAAGAGCAAGCTGAATATCAAGAAACGTTCGATAAGGTCGCCCGTATTTTACCGCAA
CTGGGGGAGTGTGTTATTTC

Downstream 100 bases:

>100_bases
CTCATAAAGCCGCCATTTGGCGGCTGTTAACCTGTGACATCCGTCACATCGTGCAGCTAAAAAACAGTAATAACAGCATA
AAGCGATCCTTGTCACCTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADP
DDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHS
LDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI

Sequences:

>Translated_199_residues
MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADP
DDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHS
LDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI
>Mature_198_residues
SELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPD
DQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSL
DIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Homo sapiens, GI157785656, Length=111, Percent_Identity=39.6396396396396, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI32469515, Length=106, Percent_Identity=41.5094339622642, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1788115, Length=190, Percent_Identity=57.3684210526316, Blast_Score=196, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17536993, Length=171, Percent_Identity=31.5789473684211, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859683, Length=138, Percent_Identity=36.231884057971, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDL_YERP3 (A7FJ95)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001401323.1
- ProteinModelPortal:   A7FJ95
- SMR:   A7FJ95
- STRING:   A7FJ95
- GeneID:   5384982
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_2354
- eggNOG:   COG0494
- HOGENOM:   HBG729456
- OMA:   PAHETVT
- ProtClustDB:   PRK10707
- BioCyc:   YPSE349747:YPSIP31758_2354-MONOMER
- HAMAP:   MF_01592
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 22245; Mature: 22113

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX; PS01293 NUDIX_COA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRR
CCCCHHHHHHHHHHHHHEECCCCCCCEEECCHHCCCCCCCEEEEEEEEECCCCCEEEEHH
ADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYH
HHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEE
VTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQ
EEEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCHHECCCCCEEEEEEEECCE
FIWGLTATIIRHLAQQVSI
EEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRR
CCCHHHHHHHHHHHHHEECCCCCCCEEECCHHCCCCCCCEEEEEEEEECCCCCEEEEHH
ADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYH
HHHHHHHCCCEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCEE
VTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQ
EEEEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHHHHHCCHHECCCCCEEEEEEEECCE
FIWGLTATIIRHLAQQVSI
EEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA