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The map label for this gene is pabB [H]

Identifier: 170024674

GI number: 170024674

Start: 2680983

End: 2682359

Strand: Direct

Name: pabB [H]

Synonym: YPK_2449

Alternate gene names: 170024674

Gene position: 2680983-2682359 (Clockwise)

Preceding gene: 170024672

Following gene: 170024675

Centisome position: 57.17

GC content: 51.13

Gene sequence:

>1377_bases
ATGTGTGAGAAATTTTTAACCGTCAAAGAGTTACCTTATCACCCTGATGCCCTGCTTCAACAATTCACCCCACTTGCCAA
CCAAGCTTGGGCGATGTTGTTGCACTCAGGATTTGCTCAACACCCCCATAGTCGCTTTGATATCTTGGTCGCTGATCCAA
AAATAACGCTGACAACTCATGGGGATAAAACGGTTATTGTCAGTGATCAGGGGCAGGAAACCTCCCTCGCGGATCCCTTC
TCTTTGCTGCAGCAGCAACTGGATAAATTCGCCCCAGCGATGCCTGCTCACCCTGATCTGCCGTTTCAGGGCGGAGCGTT
AGGGCTATTTGGTTACGACTTAGGCCGCCGAGTTGAAAAATTGCCTGAACTGGCGGCGCACGATATCGCCTTGCCGGATA
TGGCCATTGGCCTGTATGACTGGGCGCTCATTGCTGACCACTCTCGGCAGAAGCTCACGCTGGTATCCCTTGGCGATGCC
GAACAGCGCTTGCATTGGCTGCATCAGCAAACAACCGATGAGAACCTCGTCCCCTTCAAACTCACGGTTCCATGGCAGGC
AGATATGTCACGGGAGCAGTACGGCGAAAAATTCCGCCAAATTCAAGCGTATCTGCGTAGCGGTGACTGTTACCAAATCA
ATCTGGCACAAAGATTCAGCGCAGAGTATCAGGGGGATGAATGGCAAGCATTTCTGTCACTGAGTCGTAGCAATCAAGCC
CCCTTTTCAGCTTTTATTCGCTTACCCGACAACGCCATATTGAGTGTTTCACCAGAACGTTTCTTGTGGTTGGAGAATCA
TCAGGTTCAAACCCGGCCGATTAAAGGTACGCTACCCCGTTTGGCCGATCCTGAGCAGGATCGCCAGCAAGCTGAGCGAT
TGGCGAATTCAGCCAAAGATCAGGCTGAAAATCTCATGATTGTGGACTTGCTGCGTAACGATATTGGCCGTGTCGCACGT
CCGGGTAGCGTCCGCGTACCAGAGCTGTTTGTGGTGGAGCCTTTTCCTGCGGTGCACCACTTAGTCAGTACAATTACCGC
AATACTTCCCCCAAAATGTTCGCCGACCGAATTACTGCGCGCCTGTTTCCCCGGCGGGTCAATTACTGGTGCCCCCAAGG
TCCGAGCAATGGAAATTATTGAACAACTCGAACCCTATCGACGCAATGCTTATTGCGGTAACATTGGCTACATAAGTTGC
TGCGGCACCATGGATACCAATATTACTATCCGTACCCTGATGACAGAGAACGGTAAGATATATTGTTCTGCCGGAGGGGG
GATTGTCGCCGACAGCCAAGAGCAAGCTGAATATCAAGAAACGTTCGATAAGGTCGCCCGTATTTTACCGCAACTGGGGG
AGTGTGTTATTTCGTGA

Upstream 100 bases:

>100_bases
GCCACCACTGTCTTAGTGATTTATGCAGCCTTGTAGCCCATTGCCAACATGTACATAAGACATCTCTTTATGACCATTCG
AAAGAAAAGAATAGCGACCT

Downstream 100 bases:

>100_bases
GTGAATTAATTACTGGGCAGTACTTGTCCGAGTTTATTAACCGTTTCCAACTACAACTGCCGCAACCCGATAACGTTTTG
ACTCATAGTCACTATTTTTC

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MCEKFLTVKELPYHPDALLQQFTPLANQAWAMLLHSGFAQHPHSRFDILVADPKITLTTHGDKTVIVSDQGQETSLADPF
SLLQQQLDKFAPAMPAHPDLPFQGGALGLFGYDLGRRVEKLPELAAHDIALPDMAIGLYDWALIADHSRQKLTLVSLGDA
EQRLHWLHQQTTDENLVPFKLTVPWQADMSREQYGEKFRQIQAYLRSGDCYQINLAQRFSAEYQGDEWQAFLSLSRSNQA
PFSAFIRLPDNAILSVSPERFLWLENHQVQTRPIKGTLPRLADPEQDRQQAERLANSAKDQAENLMIVDLLRNDIGRVAR
PGSVRVPELFVVEPFPAVHHLVSTITAILPPKCSPTELLRACFPGGSITGAPKVRAMEIIEQLEPYRRNAYCGNIGYISC
CGTMDTNITIRTLMTENGKIYCSAGGGIVADSQEQAEYQETFDKVARILPQLGECVIS

Sequences:

>Translated_458_residues
MCEKFLTVKELPYHPDALLQQFTPLANQAWAMLLHSGFAQHPHSRFDILVADPKITLTTHGDKTVIVSDQGQETSLADPF
SLLQQQLDKFAPAMPAHPDLPFQGGALGLFGYDLGRRVEKLPELAAHDIALPDMAIGLYDWALIADHSRQKLTLVSLGDA
EQRLHWLHQQTTDENLVPFKLTVPWQADMSREQYGEKFRQIQAYLRSGDCYQINLAQRFSAEYQGDEWQAFLSLSRSNQA
PFSAFIRLPDNAILSVSPERFLWLENHQVQTRPIKGTLPRLADPEQDRQQAERLANSAKDQAENLMIVDLLRNDIGRVAR
PGSVRVPELFVVEPFPAVHHLVSTITAILPPKCSPTELLRACFPGGSITGAPKVRAMEIIEQLEPYRRNAYCGNIGYISC
CGTMDTNITIRTLMTENGKIYCSAGGGIVADSQEQAEYQETFDKVARILPQLGECVIS
>Mature_458_residues
MCEKFLTVKELPYHPDALLQQFTPLANQAWAMLLHSGFAQHPHSRFDILVADPKITLTTHGDKTVIVSDQGQETSLADPF
SLLQQQLDKFAPAMPAHPDLPFQGGALGLFGYDLGRRVEKLPELAAHDIALPDMAIGLYDWALIADHSRQKLTLVSLGDA
EQRLHWLHQQTTDENLVPFKLTVPWQADMSREQYGEKFRQIQAYLRSGDCYQINLAQRFSAEYQGDEWQAFLSLSRSNQA
PFSAFIRLPDNAILSVSPERFLWLENHQVQTRPIKGTLPRLADPEQDRQQAERLANSAKDQAENLMIVDLLRNDIGRVAR
PGSVRVPELFVVEPFPAVHHLVSTITAILPPKCSPTELLRACFPGGSITGAPKVRAMEIIEQLEPYRRNAYCGNIGYISC
CGTMDTNITIRTLMTENGKIYCSAGGGIVADSQEQAEYQETFDKVARILPQLGECVIS

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=446, Percent_Identity=66.5919282511211, Blast_Score=605, Evalue=1e-174,
Organism=Escherichia coli, GI1787518, Length=395, Percent_Identity=33.9240506329114, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87082077, Length=197, Percent_Identity=27.4111675126904, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786809, Length=219, Percent_Identity=25.5707762557078, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=439, Percent_Identity=31.6628701594533, Blast_Score=205, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6324361, Length=395, Percent_Identity=27.5949367088608, Blast_Score=149, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 51245; Mature: 51245

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCEKFLTVKELPYHPDALLQQFTPLANQAWAMLLHSGFAQHPHSRFDILVADPKITLTTH
CCCCCCCHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEC
GDKTVIVSDQGQETSLADPFSLLQQQLDKFAPAMPAHPDLPFQGGALGLFGYDLGRRVEK
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
LPELAAHDIALPDMAIGLYDWALIADHSRQKLTLVSLGDAEQRLHWLHQQTTDENLVPFK
HHHHHHHCCCCCHHHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEE
LTVPWQADMSREQYGEKFRQIQAYLRSGDCYQINLAQRFSAEYQGDEWQAFLSLSRSNQA
EECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCHHHHHHHHHCCCCC
PFSAFIRLPDNAILSVSPERFLWLENHQVQTRPIKGTLPRLADPEQDRQQAERLANSAKD
CCEEEEECCCCCEEEECCCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QAENLMIVDLLRNDIGRVARPGSVRVPELFVVEPFPAVHHLVSTITAILPPKCSPTELLR
HHCCEEHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHH
ACFPGGSITGAPKVRAMEIIEQLEPYRRNAYCGNIGYISCCGTMDTNITIRTLMTENGKI
HHCCCCCCCCCCCHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCCCEEEEEEEECCCEE
YCSAGGGIVADSQEQAEYQETFDKVARILPQLGECVIS
EEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCEKFLTVKELPYHPDALLQQFTPLANQAWAMLLHSGFAQHPHSRFDILVADPKITLTTH
CCCCCCCHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEEEEEC
GDKTVIVSDQGQETSLADPFSLLQQQLDKFAPAMPAHPDLPFQGGALGLFGYDLGRRVEK
CCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEHHHHHHHHHHH
LPELAAHDIALPDMAIGLYDWALIADHSRQKLTLVSLGDAEQRLHWLHQQTTDENLVPFK
HHHHHHHCCCCCHHHHHHHHHHHEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCEEEE
LTVPWQADMSREQYGEKFRQIQAYLRSGDCYQINLAQRFSAEYQGDEWQAFLSLSRSNQA
EECCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEHHHHHCCCCCCCHHHHHHHHHCCCCC
PFSAFIRLPDNAILSVSPERFLWLENHQVQTRPIKGTLPRLADPEQDRQQAERLANSAKD
CCEEEEECCCCCEEEECCCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QAENLMIVDLLRNDIGRVARPGSVRVPELFVVEPFPAVHHLVSTITAILPPKCSPTELLR
HHCCEEHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHH
ACFPGGSITGAPKVRAMEIIEQLEPYRRNAYCGNIGYISCCGTMDTNITIRTLMTENGKI
HHCCCCCCCCCCCHHHHHHHHHHCHHHHCCCCCCCCEEEEECCCCCCEEEEEEEECCCEE
YCSAGGGIVADSQEQAEYQETFDKVARILPQLGECVIS
EEECCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]