Click here to switch to the map view.

The map label for this gene is dmsB [H]

Identifier: 170023696

GI number: 170023696

Start: 1605517

End: 1606134

Strand: Reverse

Name: dmsB [H]

Synonym: YPK_1455

Alternate gene names: 170023696

Gene position: 1606134-1605517 (Counterclockwise)

Preceding gene: 170023697

Following gene: 170023695

Centisome position: 34.25

GC content: 50.81

Gene sequence:

>618_bases
ATGAAGCAATATGGTTTTTTTGTTGACTCCACCAAGTGCACGGGGTGTAAAACCTGCCAAGTCAGTTGTAAGGACGAAAA
GAATCTGGACCTTGGGCCGAAACTGCGTCGGGTCTATGAATACGGAGGAGGCAGTTGGACCCAACAGGACAATATCTGGG
TACAAAATGTCTTCAGTTATTATCTGTCCATTGCCTGTAACCACTGTTCGTCACCCACCTGTGTGACAGGCTGCCCAACG
GGTGCCATGCACAAACGTGAAGAAGACGGTTTGGTGGTGGTTAATCAGGATCTGTGTGTCGGGTGCCGCTATTGCGAAAT
GCGCTGCCCTTACGGTGCGCCACAATTTGATGCCAAAAAACAGCTAATGACCAAGTGTGATGGCTGCTACGAACGCGTGG
CTCAAGGGGATAAGCCCGTCTGCGTCGATTCTTGCCCACAACGCGCGTTGGATTTCGATGAAATCTCGGTGTTACGTGAT
AAATACGGTGACGAAAATGCAATTGCACCGTTACCCCATGCGCATCTGACACAGCCTAATCTCGTGATTCGTGGCCACCG
CGATGCAAAACCATCCGGTGATACATCAGGCCGCATCCAAAACCCGGCGGAGGTATAA

Upstream 100 bases:

>100_bases
GTATCAATACGTTGACGACACAACGCCCTTCGCCATTGGCGAAAGGTAATCCTCAACACACCAACCTCGTTGAAGTAAAA
CGTGCATAAGGAGCTGAATA

Downstream 100 bases:

>100_bases
AATGCATGAATTACCTTTAGTATTTTTTACCGTGCTCGGGCAGACCGCCGTCGGGCTGTTTACACTGGCGTGGCTCAGTA
ACAAGCTAGGGATGACCACG

Product: dimethylsulfoxide reductase subunit B

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MKQYGFFVDSTKCTGCKTCQVSCKDEKNLDLGPKLRRVYEYGGGSWTQQDNIWVQNVFSYYLSIACNHCSSPTCVTGCPT
GAMHKREEDGLVVVNQDLCVGCRYCEMRCPYGAPQFDAKKQLMTKCDGCYERVAQGDKPVCVDSCPQRALDFDEISVLRD
KYGDENAIAPLPHAHLTQPNLVIRGHRDAKPSGDTSGRIQNPAEV

Sequences:

>Translated_205_residues
MKQYGFFVDSTKCTGCKTCQVSCKDEKNLDLGPKLRRVYEYGGGSWTQQDNIWVQNVFSYYLSIACNHCSSPTCVTGCPT
GAMHKREEDGLVVVNQDLCVGCRYCEMRCPYGAPQFDAKKQLMTKCDGCYERVAQGDKPVCVDSCPQRALDFDEISVLRD
KYGDENAIAPLPHAHLTQPNLVIRGHRDAKPSGDTSGRIQNPAEV
>Mature_205_residues
MKQYGFFVDSTKCTGCKTCQVSCKDEKNLDLGPKLRRVYEYGGGSWTQQDNIWVQNVFSYYLSIACNHCSSPTCVTGCPT
GAMHKREEDGLVVVNQDLCVGCRYCEMRCPYGAPQFDAKKQLMTKCDGCYERVAQGDKPVCVDSCPQRALDFDEISVLRD
KYGDENAIAPLPHAHLTQPNLVIRGHRDAKPSGDTSGRIQNPAEV

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=203, Percent_Identity=61.0837438423645, Blast_Score=281, Evalue=2e-77,
Organism=Escherichia coli, GI1787872, Length=203, Percent_Identity=60.0985221674877, Blast_Score=278, Evalue=2e-76,
Organism=Escherichia coli, GI1789370, Length=202, Percent_Identity=28.7128712871287, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787740, Length=94, Percent_Identity=44.6808510638298, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1787478, Length=95, Percent_Identity=44.2105263157895, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI2367345, Length=155, Percent_Identity=32.9032258064516, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI226510944, Length=151, Percent_Identity=32.4503311258278, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1790326, Length=154, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787749, Length=154, Percent_Identity=31.1688311688312, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI2367245, Length=147, Percent_Identity=31.2925170068027, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI87082179, Length=158, Percent_Identity=30.379746835443, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1789067, Length=184, Percent_Identity=29.8913043478261, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI87082180, Length=147, Percent_Identity=25.8503401360544, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787963, Length=145, Percent_Identity=24.8275862068966, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788811, Length=162, Percent_Identity=27.1604938271605, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 22803; Mature: 22803

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
9.8 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
9.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYGFFVDSTKCTGCKTCQVSCKDEKNLDLGPKLRRVYEYGGGSWTQQDNIWVQNVFSY
CCCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHH
YLSIACNHCSSPTCVTGCPTGAMHKREEDGLVVVNQDLCVGCRYCEMRCPYGAPQFDAKK
HHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCEECCCEEEEECCCCCCCCHHHH
QLMTKCDGCYERVAQGDKPVCVDSCPQRALDFDEISVLRDKYGDENAIAPLPHAHLTQPN
HHHHHHHHHHHHHHCCCCCEECCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LVIRGHRDAKPSGDTSGRIQNPAEV
EEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKQYGFFVDSTKCTGCKTCQVSCKDEKNLDLGPKLRRVYEYGGGSWTQQDNIWVQNVFSY
CCCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHH
YLSIACNHCSSPTCVTGCPTGAMHKREEDGLVVVNQDLCVGCRYCEMRCPYGAPQFDAKK
HHHHHHHCCCCCCEEECCCCCCCCCCCCCCEEEECCCCEECCCEEEEECCCCCCCCHHHH
QLMTKCDGCYERVAQGDKPVCVDSCPQRALDFDEISVLRDKYGDENAIAPLPHAHLTQPN
HHHHHHHHHHHHHHCCCCCEECCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LVIRGHRDAKPSGDTSGRIQNPAEV
EEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062312; 8905232; 9278503; 2174699; 1653010 [H]