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The map label for this gene is mmgC [H]

Identifier: 169628951

GI number: 169628951

Start: 1859977

End: 1861137

Strand: Direct

Name: mmgC [H]

Synonym: MAB_1863

Alternate gene names: 169628951

Gene position: 1859977-1861137 (Clockwise)

Preceding gene: 169628950

Following gene: 169628952

Centisome position: 36.71

GC content: 62.1

Gene sequence:

>1161_bases
ATGTCCGAACTGTTCCCTGCCTACCGTGCGTCCTGGGAGACCGACGCGCACCGCGACCTGCGTAAGCATGCCGCCGAATT
CCTGCGCAAGGAATCCACGCCCAACCAGGAACGTTGGAGCGCCCAGCATCAGGTGGACCGTGAGTTCTGGAACAAGATGG
GCGATGCGGGTCTGTTGGGCCTGGACCTTCCGGAGGAATACGGTGGTGCCGGCGGTGATTTCGGATTCTCGGCGGTGGTG
GGCGAAGAACTGGCGCTCGCGCAGGACACCTCGACCGGATGGGCCGTGCACTCGCCGATCGTCGCGCACTACATCAACAC
CTACGGCAATGAGGAGCAGCGTGCCCGCTGGATGCCGGGCATCATCAGTGGCGATTTGGTCCTCGCCATCGCGATGACCG
AGCCCGGCACCGGCTCGGACCTGCAGGCGGTGCGCACCACCGCGATTCCCGACGGTGACCACTACGTCATCAACGGATCG
AAAACCTTCATCTCCAACGGAACTCACTGTGACCTGCTGGTCATTGTCGCCAAGACTGACCCATCTCAGGGTGCCGCCGG
CGTCTCACTCATCGTCGCCGAAACCAAGGATCTCCCCGGATTCGAGCGCGGTCGGGTGCTGGAGAAGGTGGGTCAGCACG
GTCAGGACACGCGGGAGCTGTTCTTCACCGACATGCGTGTGCCGATCGCAAACCGCCTCGGCGACAAGGACGGCCTGGGC
TTCTACCAGCTCATGGAACAGCTGGCCCGCGAGCGGCTGATCATCGCCGCCGTCTGCTCCGGCATGGCCGAGGGCGCCTT
GATCGAGGCCATCAAGTACACCAAGGAACGCGAGGCATTCGGCAAGCCGCTCATCAAATTCCAGAACACCAAATTCCAGC
TGGCCGAGCTCAAGGCCGAGGTGCTGTCCATCAAGACCACGGTGGACTACTGCGTTCAGGACTACATCAACGGGAACAAC
GACCCGGCAACGGCATCCATGGCCAAGCTGATCGCCGCGGATAAGGCGGTCTCGGTGGTGGACCGTTGTGTGCAGTTCTT
CGGCGGTTACGGATACATGATGGAGTACCCGATCGCACGGGCCTACGCCGCGGCGCGCGTCAACAAAATCTACGGCGGTA
CAAGCGAAATCATGAAGGAAATCATCAGCCGGTCCCTGTAG

Upstream 100 bases:

>100_bases
GCACACATGAAAGTCTGCGTACCGCGTTCTCCGGCAAGACCATCGCCCAGCTCGAAGCCATTGCGGCCGAGGCCGATATC
CCTCTGAATGGAGTGAAGTA

Downstream 100 bases:

>100_bases
ACGGCGCGAAGGAGACATGCAATGAAGCAGCAGAACAAGGTGTTCGTCGTCGGTGTCGGCATGACCAAATTCGAGAAGCC
CGGGCGCAGGGAGGGCTGGG

Product: acyl-CoA dehydrogenase FadE

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVDREFWNKMGDAGLLGLDLPEEYGGAGGDFGFSAVV
GEELALAQDTSTGWAVHSPIVAHYINTYGNEEQRARWMPGIISGDLVLAIAMTEPGTGSDLQAVRTTAIPDGDHYVINGS
KTFISNGTHCDLLVIVAKTDPSQGAAGVSLIVAETKDLPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLG
FYQLMEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQLAELKAEVLSIKTTVDYCVQDYINGNN
DPATASMAKLIAADKAVSVVDRCVQFFGGYGYMMEYPIARAYAAARVNKIYGGTSEIMKEIISRSL

Sequences:

>Translated_386_residues
MSELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVDREFWNKMGDAGLLGLDLPEEYGGAGGDFGFSAVV
GEELALAQDTSTGWAVHSPIVAHYINTYGNEEQRARWMPGIISGDLVLAIAMTEPGTGSDLQAVRTTAIPDGDHYVINGS
KTFISNGTHCDLLVIVAKTDPSQGAAGVSLIVAETKDLPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLG
FYQLMEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQLAELKAEVLSIKTTVDYCVQDYINGNN
DPATASMAKLIAADKAVSVVDRCVQFFGGYGYMMEYPIARAYAAARVNKIYGGTSEIMKEIISRSL
>Mature_385_residues
SELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVDREFWNKMGDAGLLGLDLPEEYGGAGGDFGFSAVVG
EELALAQDTSTGWAVHSPIVAHYINTYGNEEQRARWMPGIISGDLVLAIAMTEPGTGSDLQAVRTTAIPDGDHYVINGSK
TFISNGTHCDLLVIVAKTDPSQGAAGVSLIVAETKDLPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLGF
YQLMEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQLAELKAEVLSIKTTVDYCVQDYINGNND
PATASMAKLIAADKAVSVVDRCVQFFGGYGYMMEYPIARAYAAARVNKIYGGTSEIMKEIISRSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=373, Percent_Identity=44.7721179624665, Blast_Score=316, Evalue=3e-86,
Organism=Homo sapiens, GI226958412, Length=378, Percent_Identity=32.2751322751323, Blast_Score=215, Evalue=4e-56,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=32.3529411764706, Blast_Score=205, Evalue=5e-53,
Organism=Homo sapiens, GI226958414, Length=394, Percent_Identity=31.9796954314721, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4557233, Length=385, Percent_Identity=33.7662337662338, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=29.6791443850267, Blast_Score=182, Evalue=6e-46,
Organism=Homo sapiens, GI187960098, Length=377, Percent_Identity=32.3607427055703, Blast_Score=181, Evalue=7e-46,
Organism=Homo sapiens, GI4557231, Length=377, Percent_Identity=32.3607427055703, Blast_Score=181, Evalue=9e-46,
Organism=Homo sapiens, GI21361497, Length=348, Percent_Identity=30.7471264367816, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI4557235, Length=391, Percent_Identity=28.9002557544757, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI76496475, Length=391, Percent_Identity=28.9002557544757, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI4503943, Length=346, Percent_Identity=28.3236994219653, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI48976061, Length=289, Percent_Identity=29.757785467128, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI211971008, Length=289, Percent_Identity=29.757785467128, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI7669494, Length=320, Percent_Identity=28.75, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38505218, Length=333, Percent_Identity=27.027027027027, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI87081958, Length=345, Percent_Identity=30.4347826086957, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786223, Length=360, Percent_Identity=26.6666666666667, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17538396, Length=370, Percent_Identity=34.3243243243243, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=33.8709677419355, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI17569725, Length=380, Percent_Identity=32.3684210526316, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=31.6062176165803, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=329, Percent_Identity=32.5227963525836, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17551932, Length=392, Percent_Identity=32.1428571428571, Blast_Score=185, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=31.7204301075269, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=329, Percent_Identity=33.1306990881459, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17505929, Length=374, Percent_Identity=31.5508021390374, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI71990804, Length=287, Percent_Identity=34.8432055749129, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71985184, Length=349, Percent_Identity=29.7994269340974, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=33.7662337662338, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=29.3478260869565, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=273, Percent_Identity=31.5018315018315, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17534353, Length=379, Percent_Identity=26.3852242744063, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=290, Percent_Identity=28.2758620689655, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21355753, Length=388, Percent_Identity=32.2164948453608, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=30.8510638297872, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24660351, Length=383, Percent_Identity=31.8537859007833, Blast_Score=178, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=31.7333333333333, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24666513, Length=377, Percent_Identity=28.6472148541114, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281363737, Length=360, Percent_Identity=29.4444444444444, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI19920834, Length=366, Percent_Identity=24.8633879781421, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42391; Mature: 42259

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVDREFWNKMGDAGLLG
CCCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LDLPEEYGGAGGDFGFSAVVGEELALAQDTSTGWAVHSPIVAHYINTYGNEEQRARWMPG
CCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHCCCC
IISGDLVLAIAMTEPGTGSDLQAVRTTAIPDGDHYVINGSKTFISNGTHCDLLVIVAKTD
CCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCEEEECCCEEEECCCCCEEEEEEEEECC
PSQGAAGVSLIVAETKDLPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLG
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCCCCCC
FYQLMEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQLAELKAE
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
VLSIKTTVDYCVQDYINGNNDPATASMAKLIAADKAVSVVDRCVQFFGGYGYMMEYPIAR
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AYAAARVNKIYGGTSEIMKEIISRSL
HHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SELFPAYRASWETDAHRDLRKHAAEFLRKESTPNQERWSAQHQVDREFWNKMGDAGLLG
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LDLPEEYGGAGGDFGFSAVVGEELALAQDTSTGWAVHSPIVAHYINTYGNEEQRARWMPG
CCCCHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHCCCC
IISGDLVLAIAMTEPGTGSDLQAVRTTAIPDGDHYVINGSKTFISNGTHCDLLVIVAKTD
CCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCEEEECCCEEEECCCCCEEEEEEEEECC
PSQGAAGVSLIVAETKDLPGFERGRVLEKVGQHGQDTRELFFTDMRVPIANRLGDKDGLG
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHCCCCCCCC
FYQLMEQLARERLIIAAVCSGMAEGALIEAIKYTKEREAFGKPLIKFQNTKFQLAELKAE
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHH
VLSIKTTVDYCVQDYINGNNDPATASMAKLIAADKAVSVVDRCVQFFGGYGYMMEYPIAR
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AYAAARVNKIYGGTSEIMKEIISRSL
HHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]