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The map label for this gene is yneF [H]

Identifier: 169628927

GI number: 169628927

Start: 1838612

End: 1839703

Strand: Direct

Name: yneF [H]

Synonym: MAB_1839

Alternate gene names: 169628927

Gene position: 1838612-1839703 (Clockwise)

Preceding gene: 169628926

Following gene: 169628931

Centisome position: 36.28

GC content: 64.38

Gene sequence:

>1092_bases
GTGGTTACCACATATCCGGGTCGGAACGGCTTCGGATCAGAGTCGAACCGGTGTAGTACAGGCGCACAGGTTTACGGGGC
CAACAACGACATTCTTGAACGGGTCGGGCTGCGGCGACCGGTCTCGCGGGCGAACGCGGTATTCATCACGGCCGTCGGTG
CGGCGGCAATCCTGCTCGCCGCCACGGGAATGTCGACAATTCCCTTGCTGTGTATCTCCCTGTCGATTCCGGCGTTCCTC
TGGGGAATTCGTTACGCGAGGGCCCGGGCGGTGACCTATGGGGAGTCGGTCGCGTACGTCCTGTACTGCGATGTGGCCAT
TCTGATCGGCATCTGCGTCGTGACGACGACCGGCGTCGCCTTTGTGAAGTTGGCGTGGCTACTGGCGGTCAGCGCGTACG
TATCCCTGGTCCATGGCCGGGTGGCGGTCGCGATGCAATCGCTGGTGACCACTGCCGGAACCGTGCTGGCGGTAGTGGGA
GCGGTATCCCGCGACGAGTACTCGGCGGCCGCTCTCGCCGCGGCGGTGGTAACGATGCTGTTGGCGAATCTGTTTGCCGG
ATTGGTCATCTACGTGGGTAAGGCGCAGTTCAGTGAGCACGCCGACGGGCGAGATCGCCTGGCGCGCCACGATGTGCTGA
CCGGCCTGCTGAACAGGCGCGGTCTGCAGGAAGCATATGAGGCCACGGTCGGCGTTCCCGGCATGCACGTGACTGTCGTG
GTGGTCGATCTGAACCTGTTCAAGCAGATCAACGATACCTTCGGTCACCATGTCGGTGATCAGGTGCTGCAACGCACGGC
GCACCGGCTGCGATCGGTGGTGGGGCCGGATGCCTTGTTGGCCAGGCTCGGTGGCGATGAGTTCGGCATCGTGGTGGTCG
GCGACGCGCCACCGCACATCGACTATCAGCGGGCGGTGGAAGAGGCGTTGAACAGTGCGAGCGAGGACGTCCCGGTGAGC
GCCAGCGTCGGGGTCGCCGCCGCGATCCTGCCCGAATCGGACCGTACGACGATCCACACCCTGGGGCCCATCGTCACCCA
CCTTTTGGTCGAGGCTGACGGCGCGATGTACGGCGCCAAGAAGGCGGGATAG

Upstream 100 bases:

>100_bases
TGGATTGGGGATTGGCGGTGACCACAGTTGGCTGGCCGTCGATTGGGTCGGGCAATGTCGGTTTGCGGTGTGTCGATGGT
TGCTTGGGTAGGGGCGATAC

Downstream 100 bases:

>100_bases
TTCGGCGGCGGCCCGGACACCAGGCCGCCGCCAACAACTTCCGCCCGGCTACCAGACGCGCACGTAGTCGACGAGCATCT
CCGCCGGGTACGAGCCGCCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MVTTYPGRNGFGSESNRCSTGAQVYGANNDILERVGLRRPVSRANAVFITAVGAAAILLAATGMSTIPLLCISLSIPAFL
WGIRYARARAVTYGESVAYVLYCDVAILIGICVVTTTGVAFVKLAWLLAVSAYVSLVHGRVAVAMQSLVTTAGTVLAVVG
AVSRDEYSAAALAAAVVTMLLANLFAGLVIYVGKAQFSEHADGRDRLARHDVLTGLLNRRGLQEAYEATVGVPGMHVTVV
VVDLNLFKQINDTFGHHVGDQVLQRTAHRLRSVVGPDALLARLGGDEFGIVVVGDAPPHIDYQRAVEEALNSASEDVPVS
ASVGVAAAILPESDRTTIHTLGPIVTHLLVEADGAMYGAKKAG

Sequences:

>Translated_363_residues
MVTTYPGRNGFGSESNRCSTGAQVYGANNDILERVGLRRPVSRANAVFITAVGAAAILLAATGMSTIPLLCISLSIPAFL
WGIRYARARAVTYGESVAYVLYCDVAILIGICVVTTTGVAFVKLAWLLAVSAYVSLVHGRVAVAMQSLVTTAGTVLAVVG
AVSRDEYSAAALAAAVVTMLLANLFAGLVIYVGKAQFSEHADGRDRLARHDVLTGLLNRRGLQEAYEATVGVPGMHVTVV
VVDLNLFKQINDTFGHHVGDQVLQRTAHRLRSVVGPDALLARLGGDEFGIVVVGDAPPHIDYQRAVEEALNSASEDVPVS
ASVGVAAAILPESDRTTIHTLGPIVTHLLVEADGAMYGAKKAG
>Mature_363_residues
MVTTYPGRNGFGSESNRCSTGAQVYGANNDILERVGLRRPVSRANAVFITAVGAAAILLAATGMSTIPLLCISLSIPAFL
WGIRYARARAVTYGESVAYVLYCDVAILIGICVVTTTGVAFVKLAWLLAVSAYVSLVHGRVAVAMQSLVTTAGTVLAVVG
AVSRDEYSAAALAAAVVTMLLANLFAGLVIYVGKAQFSEHADGRDRLARHDVLTGLLNRRGLQEAYEATVGVPGMHVTVV
VVDLNLFKQINDTFGHHVGDQVLQRTAHRLRSVVGPDALLARLGGDEFGIVVVGDAPPHIDYQRAVEEALNSASEDVPVS
ASVGVAAAILPESDRTTIHTLGPIVTHLLVEADGAMYGAKKAG

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787802, Length=164, Percent_Identity=33.5365853658537, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786584, Length=341, Percent_Identity=26.9794721407625, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788085, Length=195, Percent_Identity=31.2820512820513, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=31.5789473684211, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI145693134, Length=174, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787541, Length=163, Percent_Identity=32.5153374233129, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=31.9277108433735, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081974, Length=132, Percent_Identity=30.3030303030303, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788381, Length=164, Percent_Identity=30.4878048780488, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=30.3571428571429, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160 [H]

Pfam domain/function: PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 38030; Mature: 38030

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTYPGRNGFGSESNRCSTGAQVYGANNDILERVGLRRPVSRANAVFITAVGAAAILLA
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHCCEEEEEHHHHHHHHHH
ATGMSTIPLLCISLSIPAFLWGIRYARARAVTYGESVAYVLYCDVAILIGICVVTTTGVA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVKLAWLLAVSAYVSLVHGRVAVAMQSLVTTAGTVLAVVGAVSRDEYSAAALAAAVVTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LANLFAGLVIYVGKAQFSEHADGRDRLARHDVLTGLLNRRGLQEAYEATVGVPGMHVTVV
HHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEE
VVDLNLFKQINDTFGHHVGDQVLQRTAHRLRSVVGPDALLARLGGDEFGIVVVGDAPPHI
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCC
DYQRAVEEALNSASEDVPVSASVGVAAAILPESDRTTIHTLGPIVTHLLVEADGAMYGAK
CHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
KAG
CCC
>Mature Secondary Structure
MVTTYPGRNGFGSESNRCSTGAQVYGANNDILERVGLRRPVSRANAVFITAVGAAAILLA
CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHCCCCCHHHCCEEEEEHHHHHHHHHH
ATGMSTIPLLCISLSIPAFLWGIRYARARAVTYGESVAYVLYCDVAILIGICVVTTTGVA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVKLAWLLAVSAYVSLVHGRVAVAMQSLVTTAGTVLAVVGAVSRDEYSAAALAAAVVTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LANLFAGLVIYVGKAQFSEHADGRDRLARHDVLTGLLNRRGLQEAYEATVGVPGMHVTVV
HHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEE
VVDLNLFKQINDTFGHHVGDQVLQRTAHRLRSVVGPDALLARLGGDEFGIVVVGDAPPHI
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEEECCCCCCC
DYQRAVEEALNSASEDVPVSASVGVAAAILPESDRTTIHTLGPIVTHLLVEADGAMYGAK
CHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
KAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]