| Definition | Mycobacterium abscessus ATCC 19977 chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010397 |
| Length | 5,067,172 |
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The map label for this gene is dnaJ2 [H]
Identifier: 169628756
GI number: 169628756
Start: 1694348
End: 1695493
Strand: Direct
Name: dnaJ2 [H]
Synonym: MAB_1666
Alternate gene names: 169628756
Gene position: 1694348-1695493 (Clockwise)
Preceding gene: 169628755
Following gene: 169628757
Centisome position: 33.44
GC content: 69.9
Gene sequence:
>1146_bases GTGGCGCGTGATTACTACGGCATCCTCGGGGTGAGCAAGGGTGCCAGCGACAGCGAGCTCAAGCGGGCCTATCGCAAGCT CGCCCGCGAGCTGCACCCCGACATCAACCCCGATGAGCAGGCGCAGGCCCGGTTCAAAGAGGTCAGCATCGCCTACGAGG TGCTGACCGACCCCGAGAAGCGGCGCGTGGTCGACCTCGGAGGCGACCCGCTGGAGAACGGCGGCGGTGGCAACGGGTTC GGCGGCTTCGGTTCGGGCTTCGGCGGCCTGGGCGACGTGTTCGAGGCATTCTTCGGCGGATCGGCGGGCGGATCACGCGG TCCGCGTGGCCGGGTGCAGCCCGGGGCCGACTCCCTGCTACGGATGCGCCTGGACCTGGTGGAATGCGCGACGGGCGTCA GCAAGCAGGTGACCGTCGACACCGCCATCCTGTGCGACGGGTGCGCCGGTAAGGGCACGCACGGAAACTCGGCACCGAGC GCCTGCGAGACCTGCGGCGGCCGTGGCGAGGTGCAGACCGTCCAGCGTTCACTGCTCGGTCAGGTACTGACATCGCGTCC CTGCCCGACCTGCCAGGGTGCCGGTGAGGTCATCACCGACCCCTGCCACAAATGTGGCGGCGACGGCCGCGTGCGGGCGC GCCGGGAGATCACCGTCAAGATCCCGGCCGGTGTCGGCGATGGGATGAGGGTGCGGTTGGCGGCCCAGGGCGAGGTCGGT CCCGGGGGCGGCCCGGCTGGCGACCTGTACGTCGAGGTGCACGAGAAGCCACACGATGTCTTCATTCGCGACGGCGACGA CCTGCACTTCACGGTGCGTGTCCCGATGGTCGAGGCGGCGCTGGGCACCAGCGTCTCCGTGGAGGCCATCCTGGACGGCG ACACCGTCATCAAGGTCGAGCCGGGCTCGCAGCCCGGGTCGGTGGTGACACTGCGTGGCAAGGGCATGCCCCATTTGCGC ACGGGCGTGCGCGGCAACCTGCACGCTCACCTCGACGTCGTGGTGCCGACCCGGCTGGACTCCAAGGAACGCGAGCTGTT GAAGGACTTCAGGGCTCGCAACAAGGAAGGTGCCGAGGTCGTGTGGGCCGAGTCGGCCTCCGGCGGGGTGTTCTCGCGGC TGCGCGAGGCCTTCACGGGGCGGTAG
Upstream 100 bases:
>100_bases TCGCGAATGTTGCGGCGGTTGCCATGTATATCGGCGAAGTGCTAGCTAATCGCTAGCAGCATGTGAAGTAGACAGATACC AACGGAGCGAGATCAACACA
Downstream 100 bases:
>100_bases ATGGCGGCAGCCACGATCTTCTACGTTCCGCGGGTTCCCTCAGCCGGGGAGCAGGTGCTGCTCGACGGGGATGAGGGCCA CCACGCGGCGCGGGTGTTGC
Product: chaperone protein DnaJ
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 381; Mature: 380
Protein sequence:
>381_residues MARDYYGILGVSKGASDSELKRAYRKLARELHPDINPDEQAQARFKEVSIAYEVLTDPEKRRVVDLGGDPLENGGGGNGF GGFGSGFGGLGDVFEAFFGGSAGGSRGPRGRVQPGADSLLRMRLDLVECATGVSKQVTVDTAILCDGCAGKGTHGNSAPS ACETCGGRGEVQTVQRSLLGQVLTSRPCPTCQGAGEVITDPCHKCGGDGRVRARREITVKIPAGVGDGMRVRLAAQGEVG PGGGPAGDLYVEVHEKPHDVFIRDGDDLHFTVRVPMVEAALGTSVSVEAILDGDTVIKVEPGSQPGSVVTLRGKGMPHLR TGVRGNLHAHLDVVVPTRLDSKERELLKDFRARNKEGAEVVWAESASGGVFSRLREAFTGR
Sequences:
>Translated_381_residues MARDYYGILGVSKGASDSELKRAYRKLARELHPDINPDEQAQARFKEVSIAYEVLTDPEKRRVVDLGGDPLENGGGGNGF GGFGSGFGGLGDVFEAFFGGSAGGSRGPRGRVQPGADSLLRMRLDLVECATGVSKQVTVDTAILCDGCAGKGTHGNSAPS ACETCGGRGEVQTVQRSLLGQVLTSRPCPTCQGAGEVITDPCHKCGGDGRVRARREITVKIPAGVGDGMRVRLAAQGEVG PGGGPAGDLYVEVHEKPHDVFIRDGDDLHFTVRVPMVEAALGTSVSVEAILDGDTVIKVEPGSQPGSVVTLRGKGMPHLR TGVRGNLHAHLDVVVPTRLDSKERELLKDFRARNKEGAEVVWAESASGGVFSRLREAFTGR >Mature_380_residues ARDYYGILGVSKGASDSELKRAYRKLARELHPDINPDEQAQARFKEVSIAYEVLTDPEKRRVVDLGGDPLENGGGGNGFG GFGSGFGGLGDVFEAFFGGSAGGSRGPRGRVQPGADSLLRMRLDLVECATGVSKQVTVDTAILCDGCAGKGTHGNSAPSA CETCGGRGEVQTVQRSLLGQVLTSRPCPTCQGAGEVITDPCHKCGGDGRVRARREITVKIPAGVGDGMRVRLAAQGEVGP GGGPAGDLYVEVHEKPHDVFIRDGDDLHFTVRVPMVEAALGTSVSVEAILDGDTVIKVEPGSQPGSVVTLRGKGMPHLRT GVRGNLHAHLDVVVPTRLDSKERELLKDFRARNKEGAEVVWAESASGGVFSRLREAFTGR
Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon
COG id: COG0484
COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 J domain [H]
Homologues:
Organism=Homo sapiens, GI5031741, Length=342, Percent_Identity=36.5497076023392, Blast_Score=178, Evalue=9e-45, Organism=Homo sapiens, GI205360838, Length=352, Percent_Identity=30.1136363636364, Blast_Score=172, Evalue=7e-43, Organism=Homo sapiens, GI205360840, Length=352, Percent_Identity=30.1136363636364, Blast_Score=171, Evalue=9e-43, Organism=Homo sapiens, GI194328758, Length=342, Percent_Identity=32.4561403508772, Blast_Score=159, Evalue=3e-39, Organism=Homo sapiens, GI194328760, Length=342, Percent_Identity=32.4561403508772, Blast_Score=159, Evalue=4e-39, Organism=Homo sapiens, GI4504511, Length=366, Percent_Identity=31.9672131147541, Blast_Score=156, Evalue=2e-38, Organism=Homo sapiens, GI7706495, Length=358, Percent_Identity=31.5642458100559, Blast_Score=126, Evalue=4e-29, Organism=Homo sapiens, GI6631085, Length=367, Percent_Identity=28.3378746594005, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI194328762, Length=306, Percent_Identity=29.4117647058824, Blast_Score=120, Evalue=2e-27, Organism=Homo sapiens, GI194306642, Length=102, Percent_Identity=48.0392156862745, Blast_Score=91, Evalue=2e-18, Organism=Homo sapiens, GI194306640, Length=102, Percent_Identity=48.0392156862745, Blast_Score=91, Evalue=2e-18, Organism=Homo sapiens, GI201862518, Length=116, Percent_Identity=37.9310344827586, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI201862587, Length=116, Percent_Identity=37.9310344827586, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI56549115, Length=116, Percent_Identity=37.9310344827586, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI23503241, Length=104, Percent_Identity=47.1153846153846, Blast_Score=82, Evalue=8e-16, Organism=Homo sapiens, GI47777312, Length=105, Percent_Identity=45.7142857142857, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI5453690, Length=69, Percent_Identity=50.7246376811594, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI17388799, Length=104, Percent_Identity=47.1153846153846, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI72534740, Length=103, Percent_Identity=42.7184466019417, Blast_Score=77, Evalue=3e-14, Organism=Homo sapiens, GI21553335, Length=100, Percent_Identity=44, Blast_Score=77, Evalue=4e-14, Organism=Homo sapiens, GI4885495, Length=114, Percent_Identity=41.2280701754386, Blast_Score=76, Evalue=5e-14, Organism=Homo sapiens, GI9558755, Length=99, Percent_Identity=40.4040404040404, Blast_Score=76, Evalue=7e-14, Organism=Homo sapiens, GI27151736, Length=105, Percent_Identity=43.8095238095238, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI88501736, Length=105, Percent_Identity=43.8095238095238, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI56687498, Length=106, Percent_Identity=40.5660377358491, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI5453980, Length=97, Percent_Identity=42.2680412371134, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI22749377, Length=103, Percent_Identity=41.747572815534, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI39204547, Length=112, Percent_Identity=35.7142857142857, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI24308127, Length=94, Percent_Identity=40.4255319148936, Blast_Score=69, Evalue=1e-11, Organism=Homo sapiens, GI29126218, Length=64, Percent_Identity=51.5625, Blast_Score=68, Evalue=2e-11, Organism=Escherichia coli, GI1786197, Length=352, Percent_Identity=43.1818181818182, Blast_Score=251, Evalue=7e-68, Organism=Escherichia coli, GI1787235, Length=150, Percent_Identity=37.3333333333333, Blast_Score=94, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17553096, Length=359, Percent_Identity=30.08356545961, Blast_Score=155, Evalue=5e-38, Organism=Caenorhabditis elegans, GI17553098, Length=359, Percent_Identity=30.08356545961, Blast_Score=154, Evalue=6e-38, Organism=Caenorhabditis elegans, GI17507263, Length=353, Percent_Identity=36.5439093484419, Blast_Score=150, Evalue=8e-37, Organism=Caenorhabditis elegans, GI17563890, Length=376, Percent_Identity=30.3191489361702, Blast_Score=124, Evalue=7e-29, Organism=Caenorhabditis elegans, GI17534355, Length=362, Percent_Identity=28.7292817679558, Blast_Score=120, Evalue=1e-27, Organism=Caenorhabditis elegans, GI212645553, Length=362, Percent_Identity=28.7292817679558, Blast_Score=104, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17554644, Length=97, Percent_Identity=54.639175257732, Blast_Score=94, Evalue=8e-20, Organism=Caenorhabditis elegans, GI17551190, Length=74, Percent_Identity=50, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17538236, Length=113, Percent_Identity=38.9380530973451, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI115532476, Length=65, Percent_Identity=50.7692307692308, Blast_Score=68, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17510335, Length=77, Percent_Identity=44.1558441558442, Blast_Score=66, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6324265, Length=351, Percent_Identity=35.8974358974359, Blast_Score=172, Evalue=1e-43, Organism=Saccharomyces cerevisiae, GI6323870, Length=370, Percent_Identity=32.7027027027027, Blast_Score=140, Evalue=3e-34, Organism=Saccharomyces cerevisiae, GI6321094, Length=377, Percent_Identity=31.0344827586207, Blast_Score=119, Evalue=6e-28, Organism=Saccharomyces cerevisiae, GI6323119, Length=384, Percent_Identity=27.0833333333333, Blast_Score=114, Evalue=2e-26, Organism=Saccharomyces cerevisiae, GI6324252, Length=451, Percent_Identity=24.390243902439, Blast_Score=103, Evalue=3e-23, Organism=Saccharomyces cerevisiae, GI6323813, Length=109, Percent_Identity=43.1192660550459, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324103, Length=71, Percent_Identity=49.2957746478873, Blast_Score=70, Evalue=7e-13, Organism=Saccharomyces cerevisiae, GI6320888, Length=91, Percent_Identity=42.8571428571429, Blast_Score=66, Evalue=7e-12, Organism=Saccharomyces cerevisiae, GI6322194, Length=99, Percent_Identity=41.4141414141414, Blast_Score=66, Evalue=1e-11, Organism=Drosophila melanogaster, GI45552813, Length=376, Percent_Identity=32.4468085106383, Blast_Score=166, Evalue=3e-41, Organism=Drosophila melanogaster, GI45549272, Length=376, Percent_Identity=32.4468085106383, Blast_Score=165, Evalue=4e-41, Organism=Drosophila melanogaster, GI45552811, Length=378, Percent_Identity=32.8042328042328, Blast_Score=165, Evalue=5e-41, Organism=Drosophila melanogaster, GI24646562, Length=345, Percent_Identity=34.2028985507246, Blast_Score=151, Evalue=6e-37, Organism=Drosophila melanogaster, GI24646560, Length=345, Percent_Identity=34.2028985507246, Blast_Score=151, Evalue=6e-37, Organism=Drosophila melanogaster, GI24646558, Length=345, Percent_Identity=34.2028985507246, Blast_Score=151, Evalue=6e-37, Organism=Drosophila melanogaster, GI24646556, Length=345, Percent_Identity=34.2028985507246, Blast_Score=151, Evalue=6e-37, Organism=Drosophila melanogaster, GI21357547, Length=345, Percent_Identity=34.2028985507246, Blast_Score=151, Evalue=6e-37, Organism=Drosophila melanogaster, GI20129487, Length=340, Percent_Identity=31.7647058823529, Blast_Score=147, Evalue=1e-35, Organism=Drosophila melanogaster, GI24584014, Length=340, Percent_Identity=31.7647058823529, Blast_Score=147, Evalue=1e-35, Organism=Drosophila melanogaster, GI19920464, Length=374, Percent_Identity=28.8770053475936, Blast_Score=133, Evalue=2e-31, Organism=Drosophila melanogaster, GI85726398, Length=372, Percent_Identity=29.0322580645161, Blast_Score=123, Evalue=3e-28, Organism=Drosophila melanogaster, GI28574949, Length=352, Percent_Identity=27.5568181818182, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24658562, Length=366, Percent_Identity=27.3224043715847, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI24658555, Length=366, Percent_Identity=27.3224043715847, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI18858081, Length=360, Percent_Identity=30.2777777777778, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI24654066, Length=115, Percent_Identity=45.2173913043478, Blast_Score=88, Evalue=1e-17, Organism=Drosophila melanogaster, GI24654070, Length=115, Percent_Identity=45.2173913043478, Blast_Score=88, Evalue=1e-17, Organism=Drosophila melanogaster, GI24654068, Length=115, Percent_Identity=45.2173913043478, Blast_Score=88, Evalue=1e-17, Organism=Drosophila melanogaster, GI24654072, Length=115, Percent_Identity=45.2173913043478, Blast_Score=88, Evalue=1e-17, Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=60.9375, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21355911, Length=94, Percent_Identity=48.936170212766, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24668492, Length=69, Percent_Identity=46.3768115942029, Blast_Score=73, Evalue=4e-13, Organism=Drosophila melanogaster, GI21358273, Length=66, Percent_Identity=56.0606060606061, Blast_Score=70, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012724 - InterPro: IPR002939 - InterPro: IPR001623 - InterPro: IPR008971 - InterPro: IPR015609 - InterPro: IPR003095 - InterPro: IPR001305 [H]
Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]
EC number: NA
Molecular weight: Translated: 40082; Mature: 39950
Theoretical pI: Translated: 6.98; Mature: 6.98
Prosite motif: PS50076 DNAJ_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.4 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 2.4 %Cys (Mature Protein) 1.1 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MARDYYGILGVSKGASDSELKRAYRKLARELHPDINPDEQAQARFKEVSIAYEVLTDPEK CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC RRVVDLGGDPLENGGGGNGFGGFGSGFGGLGDVFEAFFGGSAGGSRGPRGRVQPGADSLL CEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH RMRLDLVECATGVSKQVTVDTAILCDGCAGKGTHGNSAPSACETCGGRGEVQTVQRSLLG HHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHH QVLTSRPCPTCQGAGEVITDPCHKCGGDGRVRARREITVKIPAGVGDGMRVRLAAQGEVG HHHHCCCCCCCCCCCCHHCCHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCC PGGGPAGDLYVEVHEKPHDVFIRDGDDLHFTVRVPMVEAALGTSVSVEAILDGDTVIKVE CCCCCCCCEEEEEECCCCEEEEECCCCEEEEEECCEEHHHHCCCEEEEEEECCCEEEEEC PGSQPGSVVTLRGKGMPHLRTGVRGNLHAHLDVVVPTRLDSKERELLKDFRARNKEGAEV CCCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEE VWAESASGGVFSRLREAFTGR EEECCCCCHHHHHHHHHHCCC >Mature Secondary Structure ARDYYGILGVSKGASDSELKRAYRKLARELHPDINPDEQAQARFKEVSIAYEVLTDPEK CCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCC RRVVDLGGDPLENGGGGNGFGGFGSGFGGLGDVFEAFFGGSAGGSRGPRGRVQPGADSLL CEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHH RMRLDLVECATGVSKQVTVDTAILCDGCAGKGTHGNSAPSACETCGGRGEVQTVQRSLLG HHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHH QVLTSRPCPTCQGAGEVITDPCHKCGGDGRVRARREITVKIPAGVGDGMRVRLAAQGEVG HHHHCCCCCCCCCCCCHHCCHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCC PGGGPAGDLYVEVHEKPHDVFIRDGDDLHFTVRVPMVEAALGTSVSVEAILDGDTVIKVE CCCCCCCCEEEEEECCCCEEEEECCCCEEEEEECCEEHHHHCCCEEEEEEECCCEEEEEC PGSQPGSVVTLRGKGMPHLRTGVRGNLHAHLDVVVPTRLDSKERELLKDFRARNKEGAEV CCCCCCCEEEEECCCCCHHHHCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEE VWAESASGGVFSRLREAFTGR EEECCCCCHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11234002 [H]