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The map label for this gene is ttdA [C]

Identifier: 16764127

GI number: 16764127

Start: 825478

End: 826323

Strand: Reverse

Name: ttdA [C]

Synonym: STM0762

Alternate gene names: 16764127

Gene position: 826323-825478 (Counterclockwise)

Preceding gene: 16764129

Following gene: 16764126

Centisome position: 17.01

GC content: 40.9

Gene sequence:

>846_bases
ATGAGTCGTATATTAAATACAGAAATTATCATTCCGATTATCGAAAAACTTGTAAAAAAAGCTTGTTATGAACTGGATGA
TAATCTCATGTGTTCTTTTCGTAAAGCATATGATAAAGAAGAGTCAAAGATCGGCAAGGAAACCATTAAGATATTAATTG
ATAATGGAGAGTATGCAAAAAAAGAACAACTTGCATGCTGCCATGATACCGGCACTTGTATCGTTATAATGGAAATTGGA
CAACATGTATGCTGGGAAGGTAAGCCGCTTAAAGATCAGGTGAACCAGGGTGTTCGCCAGGGCTATGAAAATGGATACTT
AAGAAAATCCATGGTTGCAGATCCATTAGAACGTATTAATACTAATGATAATACTCCTGCAATTTTACATACTGAAATTG
TTGATGGTGACCGAGTGACAATTACCGTTATGCCAAAGGGCGGCGGTAGCGAAAATATGGGAACTTTTAAAACATTGCTT
CCCGGCGATGGTATTGATGGTATAAAAGATTTTGTTCTGGAAACTGTCCGTCGTGTAGGAGGCAATCCATGCCCTCCTTA
TATTATTGGTATCGGCGTTGGCGGTACAATGGATCACTGTTCGTGGATGGCGAAGAAAGCATTATTACGCCCTCTTGGTG
AGTTCAATGCTAAACCACTTTATGCCCAGCTCGAAGCTGAATTATTAGAGGCCGTGAATAATACAGGGATCGGCCCTTTA
GGTATGGGCGGGCGTATTACGGCGTTAGGCGTGCATGTCGATTACTATCCTTGCCATATCACTGCACTGCCAGTCGCAAT
CAATTTCCAATGTAATGCAAGCCGCCACGCTAGTGAAATCATTTAA

Upstream 100 bases:

>100_bases
TCATTTAATAAAAATAACATATTTCCTTCCTACAATGAATACGAATATCATGAAAATGTGATCAATGGATAAAACAATGC
AACATAGCACTGGAGGGAGT

Downstream 100 bases:

>100_bases
TACCTGGAGAAGCTATGATGGAATTAACATTACCATTGACTAAAGAGAAAGCGAAAACTCTTAAGGTCGGCGATATATTA
TTTCTCACTGGATTTGCTTA

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSRILNTEIIIPIIEKLVKKACYELDDNLMCSFRKAYDKEESKIGKETIKILIDNGEYAKKEQLACCHDTGTCIVIMEIG
QHVCWEGKPLKDQVNQGVRQGYENGYLRKSMVADPLERINTNDNTPAILHTEIVDGDRVTITVMPKGGGSENMGTFKTLL
PGDGIDGIKDFVLETVRRVGGNPCPPYIIGIGVGGTMDHCSWMAKKALLRPLGEFNAKPLYAQLEAELLEAVNNTGIGPL
GMGGRITALGVHVDYYPCHITALPVAINFQCNASRHASEII

Sequences:

>Translated_281_residues
MSRILNTEIIIPIIEKLVKKACYELDDNLMCSFRKAYDKEESKIGKETIKILIDNGEYAKKEQLACCHDTGTCIVIMEIG
QHVCWEGKPLKDQVNQGVRQGYENGYLRKSMVADPLERINTNDNTPAILHTEIVDGDRVTITVMPKGGGSENMGTFKTLL
PGDGIDGIKDFVLETVRRVGGNPCPPYIIGIGVGGTMDHCSWMAKKALLRPLGEFNAKPLYAQLEAELLEAVNNTGIGPL
GMGGRITALGVHVDYYPCHITALPVAINFQCNASRHASEII
>Mature_280_residues
SRILNTEIIIPIIEKLVKKACYELDDNLMCSFRKAYDKEESKIGKETIKILIDNGEYAKKEQLACCHDTGTCIVIMEIGQ
HVCWEGKPLKDQVNQGVRQGYENGYLRKSMVADPLERINTNDNTPAILHTEIVDGDRVTITVMPKGGGSENMGTFKTLLP
GDGIDGIKDFVLETVRRVGGNPCPPYIIGIGVGGTMDHCSWMAKKALLRPLGEFNAKPLYAQLEAELLEAVNNTGIGPLG
MGGRITALGVHVDYYPCHITALPVAINFQCNASRHASEII

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=273, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1790564, Length=257, Percent_Identity=32.295719844358, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1787897, Length=256, Percent_Identity=31.25, Blast_Score=96, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30831; Mature: 30700

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS00244 REACTION_CENTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILNTEIIIPIIEKLVKKACYELDDNLMCSFRKAYDKEESKIGKETIKILIDNGEYAK
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCEEEEEEECCCCCCC
KEQLACCHDTGTCIVIMEIGQHVCWEGKPLKDQVNQGVRQGYENGYLRKSMVADPLERIN
HHCCEEEECCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
TNDNTPAILHTEIVDGDRVTITVMPKGGGSENMGTFKTLLPGDGIDGIKDFVLETVRRVG
CCCCCCEEEEEEEECCCEEEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHC
GNPCPPYIIGIGVGGTMDHCSWMAKKALLRPLGEFNAKPLYAQLEAELLEAVNNTGIGPL
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
GMGGRITALGVHVDYYPCHITALPVAINFQCNASRHASEII
CCCCEEEEEEEEEEEEEEEEEEEEEEEEEEECCCHHHHHCC
>Mature Secondary Structure 
SRILNTEIIIPIIEKLVKKACYELDDNLMCSFRKAYDKEESKIGKETIKILIDNGEYAK
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHCCEEEEEEECCCCCCC
KEQLACCHDTGTCIVIMEIGQHVCWEGKPLKDQVNQGVRQGYENGYLRKSMVADPLERIN
HHCCEEEECCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCC
TNDNTPAILHTEIVDGDRVTITVMPKGGGSENMGTFKTLLPGDGIDGIKDFVLETVRRVG
CCCCCCEEEEEEEECCCEEEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHC
GNPCPPYIIGIGVGGTMDHCSWMAKKALLRPLGEFNAKPLYAQLEAELLEAVNNTGIGPL
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCC
GMGGRITALGVHVDYYPCHITALPVAINFQCNASRHASEII
CCCCEEEEEEEEEEEEEEEEEEEEEEEEEEECCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]