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The map label for this gene is oxaA [H]

Identifier: 167626216

GI number: 167626216

Start: 5224189

End: 5225823

Strand: Reverse

Name: oxaA [H]

Synonym: Shal_4311

Alternate gene names: 167626216

Gene position: 5225823-5224189 (Counterclockwise)

Preceding gene: 167626217

Following gene: 167626215

Centisome position: 99.98

GC content: 43.49

Gene sequence:

>1635_bases
ATGGAATCTCAACGCAATATATTGCTGATCGGTTTGCTGTTTGTCAGCTTCCTACTGTGGCAACAGTGGCAAGCAGATCA
AGCGCCTCAACCGGTGGCAGCAGCTCAAACACAGTCTTCAATTCCAGCTTCAACAGTTGCTGACTCTCACAGTTCAGATG
TGCCTGATGCTGATTCAGCCGTACCTGAAGCTATAACAGCATCTAAAGAACTGATCACCGTATTTACTGACCAACTAGAA
ATCAAAATTGATCCAGTTGGCGGTGATATTGTTTACTCTGCCCTACTTTCTCATAAGCTTGAGGAAAACGGAGATGACCC
GTTTGTTCTTCTAGAGCAGACAAACGATATCTATTATATCGCACAAAGTGGCCTTATTGGTCGTGACGGTATCGACAGTA
GCGTAAAAGGTCGAGCTCACTTTGACAGCGCTTCACGTGAGTACAAATTGGCAGACGGCCAAGACACACTTAGCGTGCCA
TTGACTTACGTTAGTGACAAAGGTGTAACTTACACAAAATCATTTGTCTTCACTCGTGGTAAGTACAACATCGCCGTTGA
TTACAAAATAAACAACACTTCTGATGCTTCGCTTCAAGTTCAAATGTATGGACAGATCAAGCACAGCATCAAGAAGAGCG
AAAGCAGCATGATGATGCCAACCTATCTTGGTGGTGCTTTCTCTACAGATGATATTCGTTACGAAAAGTACAGCTTCGAT
GATATGGCTGACAAAAACCTAGATGATTCAACACTAGGTGGCTGGGTTGCTATGCTGCAACATTACTTCGTATCAGCATG
GGTACCACCAGCAACTGAAAAGAACATTATCTTCTCTAGCATGAAGAATGGTCTTGCTAATATTGGTTTCCGTGGCGAGC
TACATGATATTGCACCCGGTAGCGAACAGGTTATTAAGTCTGAGTTCTATGTTGGTCCTAAAGATCAAAAAGCACTATCA
GTACTTTCTCCATCGCTAAACCTAGTTGTCGACTATGGCTTCCTATGGTGGTTAGCAGTACCTATCTACAAACTATTGAT
GTTCTTCCATTCAATCGTTGGTAACTGGGGCTTTGCTATTATCTTAATTACGCTAACAGTTCGTGGTTTGCTATACCCGC
TAACTAAAGCGCAATACACCTCTATGGCGAAAATGCGCAATCTACAGCCTAAGCTTGCTGAACTGAAAGAGCGTTTTGGT
GATGACCGTCAGAAGATGGGTCAAGCTATGATGGAACTGTACAAGAAAGAGAAAGTGAACCCTATGGGTGGCTGTCTACC
AATCTTGCTACAGATGCCTATCTTCATCGCACTTTACTGGGTACTACTAGAAAGTGTTGAATTGCGTCACGCGCCATTCA
TGCTTTGGATTACTGACTTGTCAGTACAAGATCCATACTACGTACTACCTATCCTAATGGGTATCTCGATGTTCGTGATG
CAGAAAATGCAGCCAATGGCACCGACGATGGACCCAATGCAAGTTAAGATGATGCAGTGGATGCCAGTAATCTTTACCGT
ATTCTTCCTATGGTTCCCAGCGGGTCTGGTTCTATACTGGTTGGTAGGTAACTTAGTCGCGATTACGCAGCAGAAAATTA
TCTATGCGGGTCTGGAGAAAAAAGGGTTAAAATAA

Upstream 100 bases:

>100_bases
GTGTTGGTTTGCAGCGAAACGCATATTAAGATGTCACCCTTTACATCCGGGCGGTGAAGACCCCGTCCCTAACAAAAAAC
ATAGGTGCGATAAATAGGTT

Downstream 100 bases:

>100_bases
CCTTTAGCTCCGACTAACAAAAAGCGGTCTAATACTGAGTATTGACCGCTTTTTTGCTTTCTATATAGAAGCCGTATTTT
TATAAACACCTGAAATTAGA

Product: 60 kDa inner membrane insertion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MESQRNILLIGLLFVSFLLWQQWQADQAPQPVAAAQTQSSIPASTVADSHSSDVPDADSAVPEAITASKELITVFTDQLE
IKIDPVGGDIVYSALLSHKLEENGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQDTLSVP
LTYVSDKGVTYTKSFVFTRGKYNIAVDYKINNTSDASLQVQMYGQIKHSIKKSESSMMMPTYLGGAFSTDDIRYEKYSFD
DMADKNLDDSTLGGWVAMLQHYFVSAWVPPATEKNIIFSSMKNGLANIGFRGELHDIAPGSEQVIKSEFYVGPKDQKALS
VLSPSLNLVVDYGFLWWLAVPIYKLLMFFHSIVGNWGFAIILITLTVRGLLYPLTKAQYTSMAKMRNLQPKLAELKERFG
DDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVLPILMGISMFVM
QKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK

Sequences:

>Translated_544_residues
MESQRNILLIGLLFVSFLLWQQWQADQAPQPVAAAQTQSSIPASTVADSHSSDVPDADSAVPEAITASKELITVFTDQLE
IKIDPVGGDIVYSALLSHKLEENGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQDTLSVP
LTYVSDKGVTYTKSFVFTRGKYNIAVDYKINNTSDASLQVQMYGQIKHSIKKSESSMMMPTYLGGAFSTDDIRYEKYSFD
DMADKNLDDSTLGGWVAMLQHYFVSAWVPPATEKNIIFSSMKNGLANIGFRGELHDIAPGSEQVIKSEFYVGPKDQKALS
VLSPSLNLVVDYGFLWWLAVPIYKLLMFFHSIVGNWGFAIILITLTVRGLLYPLTKAQYTSMAKMRNLQPKLAELKERFG
DDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVLPILMGISMFVM
QKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK
>Mature_544_residues
MESQRNILLIGLLFVSFLLWQQWQADQAPQPVAAAQTQSSIPASTVADSHSSDVPDADSAVPEAITASKELITVFTDQLE
IKIDPVGGDIVYSALLSHKLEENGDDPFVLLEQTNDIYYIAQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQDTLSVP
LTYVSDKGVTYTKSFVFTRGKYNIAVDYKINNTSDASLQVQMYGQIKHSIKKSESSMMMPTYLGGAFSTDDIRYEKYSFD
DMADKNLDDSTLGGWVAMLQHYFVSAWVPPATEKNIIFSSMKNGLANIGFRGELHDIAPGSEQVIKSEFYVGPKDQKALS
VLSPSLNLVVDYGFLWWLAVPIYKLLMFFHSIVGNWGFAIILITLTVRGLLYPLTKAQYTSMAKMRNLQPKLAELKERFG
DDRQKMGQAMMELYKKEKVNPMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVLPILMGISMFVM
QKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEKKGLK

Specific function: Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and indepe

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790140, Length=552, Percent_Identity=50.9057971014493, Blast_Score=547, Evalue=1e-157,
Organism=Drosophila melanogaster, GI24662345, Length=211, Percent_Identity=25.1184834123223, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356443, Length=211, Percent_Identity=25.1184834123223, Blast_Score=84, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019998
- InterPro:   IPR001708 [H]

Pfam domain/function: PF02096 60KD_IMP [H]

EC number: NA

Molecular weight: Translated: 61177; Mature: 61177

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADQAPQPVAAAQTQSSIPASTVADSHSSDVPDADSA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHCCCCCCCCCCCCHH
VPEAITASKELITVFTDQLEIKIDPVGGDIVYSALLSHKLEENGDDPFVLLEQTNDIYYI
CCHHHHCCHHHHEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEE
AQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQDTLSVPLTYVSDKGVTYTKSFVFTRG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEEEHEEEECC
KYNIAVDYKINNTSDASLQVQMYGQIKHSIKKSESSMMMPTYLGGAFSTDDIRYEKYSFD
EEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHCCCCEECHHHCCCCCCCCCCEEEECCCH
DMADKNLDDSTLGGWVAMLQHYFVSAWVPPATEKNIIFSSMKNGLANIGFRGELHDIAPG
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
SEQVIKSEFYVGPKDQKALSVLSPSLNLVVDYGFLWWLAVPIYKLLMFFHSIVGNWGFAI
HHHHHHHHCCCCCCCHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ILITLTVRGLLYPLTKAQYTSMAKMRNLQPKLAELKERFGDDRQKMGQAMMELYKKEKVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
PMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVLPILMGISMFVM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
QKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEK
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
KGLK
CCCC
>Mature Secondary Structure
MESQRNILLIGLLFVSFLLWQQWQADQAPQPVAAAQTQSSIPASTVADSHSSDVPDADSA
CCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHCCCCCCCCCCCCHH
VPEAITASKELITVFTDQLEIKIDPVGGDIVYSALLSHKLEENGDDPFVLLEQTNDIYYI
CCHHHHCCHHHHEEEECEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEE
AQSGLIGRDGIDSSVKGRAHFDSASREYKLADGQDTLSVPLTYVSDKGVTYTKSFVFTRG
ECCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCEEEEHEEEECC
KYNIAVDYKINNTSDASLQVQMYGQIKHSIKKSESSMMMPTYLGGAFSTDDIRYEKYSFD
EEEEEEEEEECCCCCCEEEEEEHHHHHHHHHHCCCCEECHHHCCCCCCCCCCEEEECCCH
DMADKNLDDSTLGGWVAMLQHYFVSAWVPPATEKNIIFSSMKNGLANIGFRGELHDIAPG
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
SEQVIKSEFYVGPKDQKALSVLSPSLNLVVDYGFLWWLAVPIYKLLMFFHSIVGNWGFAI
HHHHHHHHCCCCCCCHHHHHHHCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
ILITLTVRGLLYPLTKAQYTSMAKMRNLQPKLAELKERFGDDRQKMGQAMMELYKKEKVN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
PMGGCLPILLQMPIFIALYWVLLESVELRHAPFMLWITDLSVQDPYYVLPILMGISMFVM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
QKMQPMAPTMDPMQVKMMQWMPVIFTVFFLWFPAGLVLYWLVGNLVAITQQKIIYAGLEK
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHH
KGLK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA