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The map label for this gene is cysQ [H]

Identifier: 167626066

GI number: 167626066

Start: 5062834

End: 5063646

Strand: Reverse

Name: cysQ [H]

Synonym: Shal_4161

Alternate gene names: 167626066

Gene position: 5063646-5062834 (Counterclockwise)

Preceding gene: 167626067

Following gene: 167626065

Centisome position: 96.88

GC content: 47.48

Gene sequence:

>813_bases
ATGAATCCAGAGAATTATGTAGATCAAGTCATTGAAATCGCAACATTAGCAGGCAAGGAAATTCGTGATATTTATCAAAA
AGGTGATTTCGAACGCGAGATCAAATCTGATAATACGCCAGTGACCTCTGCAGATCTCGCCGCTCATGAAATCATTACTG
ATGCGCTTAAGGCGTTGACGCCCGATATCCCCGTATTATCTGAAGAAGATGCCGATATTCCGTTCGAGCAACGCTGTGAT
TGGCAACGCTACTGGTTAGTGGACCCATTGGATGGTACTGGCGAGTTTATCGCGGGTAGCGGTGATTTCTCAGTAATTAT
TGCGTTAGTTGAACATAACCGTCCGATTTTGGGCGTGGTGTATGTGCCAATGACTGAAGTCTGCTATTACGGCATTGCGG
GCTTAGGCTCCTACAAGCGTAAAGATGGAGCAGAAGTGCGCATCAGCAGTTTGCAGCTAAGCAAGGATGGTTCTGAGTCA
TTACGCTTAGCGGTAAGTCGCCGCCAAGATCCGCAATCTGTGATTAAACTTTTTAATCAGAGTAAGCACTGTGAACTGGT
GGTGCTCGGTGGCGCAGCGCTTAAAAGTTGCTTAGTCGCCGAAGGACGAGCCGATTGCTACGTACGTATTGGCCCAACTG
GTGAATGGGATACGGGTGCCGCGCAGATTATCGTTGAGGAAGCCGGTGGGCAGATCATGGATCTTAATCTACAGCCGCTG
ACTTACAATGAGCGAGAAAGCCTAGAAAACCCTAATTTTATAGTGGTCGGTGCGCCAGCACTTGAGTGGGACCAGATCCT
TATTAATGAATGA

Upstream 100 bases:

>100_bases
GAGTCTCGTAGTGTAAGTGCTTTATTTTTAGCGCAAAAACATCTACAACTAAGATAGACAAAACGACGCAGGTCATGGGT
GTTAGGCTGTTGGAGTAGTT

Downstream 100 bases:

>100_bases
TTCAACACTAATATCAATCGCTTGCAAGCAAGATCTTGCCGCGATTGATGCTCTTGAACGCCAATGTTTTGCTGGACATT
GTTATCCAGATTTTTTCTTT

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MNPENYVDQVIEIATLAGKEIRDIYQKGDFEREIKSDNTPVTSADLAAHEIITDALKALTPDIPVLSEEDADIPFEQRCD
WQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVVYVPMTEVCYYGIAGLGSYKRKDGAEVRISSLQLSKDGSES
LRLAVSRRQDPQSVIKLFNQSKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPL
TYNERESLENPNFIVVGAPALEWDQILINE

Sequences:

>Translated_270_residues
MNPENYVDQVIEIATLAGKEIRDIYQKGDFEREIKSDNTPVTSADLAAHEIITDALKALTPDIPVLSEEDADIPFEQRCD
WQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVVYVPMTEVCYYGIAGLGSYKRKDGAEVRISSLQLSKDGSES
LRLAVSRRQDPQSVIKLFNQSKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPL
TYNERESLENPNFIVVGAPALEWDQILINE
>Mature_270_residues
MNPENYVDQVIEIATLAGKEIRDIYQKGDFEREIKSDNTPVTSADLAAHEIITDALKALTPDIPVLSEEDADIPFEQRCD
WQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVVYVPMTEVCYYGIAGLGSYKRKDGAEVRISSLQLSKDGSES
LRLAVSRRQDPQSVIKLFNQSKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPL
TYNERESLENPNFIVVGAPALEWDQILINE

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=248, Percent_Identity=27.4193548387097, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5031789, Length=226, Percent_Identity=28.3185840707965, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI221625487, Length=263, Percent_Identity=26.615969581749, Blast_Score=74, Evalue=9e-14,
Organism=Escherichia coli, GI1790659, Length=251, Percent_Identity=43.8247011952191, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1788882, Length=240, Percent_Identity=30, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI193202572, Length=252, Percent_Identity=27.3809523809524, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193202570, Length=254, Percent_Identity=27.5590551181102, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71995897, Length=241, Percent_Identity=27.8008298755187, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71995905, Length=241, Percent_Identity=27.8008298755187, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24664922, Length=273, Percent_Identity=24.9084249084249, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664926, Length=237, Percent_Identity=26.5822784810127, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357329, Length=237, Percent_Identity=26.5822784810127, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29769; Mature: 29769

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPENYVDQVIEIATLAGKEIRDIYQKGDFEREIKSDNTPVTSADLAAHEIITDALKALT
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PDIPVLSEEDADIPFEQRCDWQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVV
CCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCEEEEE
YVPMTEVCYYGIAGLGSYKRKDGAEVRISSLQLSKDGSESLRLAVSRRQDPQSVIKLFNQ
ECCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCC
SKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPL
CCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCC
TYNERESLENPNFIVVGAPALEWDQILINE
CCCHHHCCCCCCEEEEECCCCCCCEEEECC
>Mature Secondary Structure
MNPENYVDQVIEIATLAGKEIRDIYQKGDFEREIKSDNTPVTSADLAAHEIITDALKALT
CCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHC
PDIPVLSEEDADIPFEQRCDWQRYWLVDPLDGTGEFIAGSGDFSVIIALVEHNRPILGVV
CCCCCCCCCCCCCCHHHCCCCEEEEEECCCCCCCCEEECCCCCEEEEEEEECCCCEEEEE
YVPMTEVCYYGIAGLGSYKRKDGAEVRISSLQLSKDGSESLRLAVSRRQDPQSVIKLFNQ
ECCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHCC
SKHCELVVLGGAALKSCLVAEGRADCYVRIGPTGEWDTGAAQIIVEEAGGQIMDLNLQPL
CCCEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCCCCCEEEEEECCCCEEEEEECCCC
TYNERESLENPNFIVVGAPALEWDQILINE
CCCHHHCCCCCCEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]