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The map label for this gene is recQ [H]

Identifier: 167622376

GI number: 167622376

Start: 509886

End: 511709

Strand: Direct

Name: recQ [H]

Synonym: Shal_0436

Alternate gene names: 167622376

Gene position: 509886-511709 (Clockwise)

Preceding gene: 167622373

Following gene: 167622378

Centisome position: 9.76

GC content: 49.29

Gene sequence:

>1824_bases
ATGGATCAGGCCGCGCTCGATAATTCAGTCGATCAGTTATCTTCCACCCTTCAGTCGGTATTTGGTTATCGTACTTTTAG
AGAGGGGCAGCGAGAGGTAATTGAACAGATCTGCGCGGGACAAGATTGCCTAGTGATCATGCCAACGGGTGGCGGTAAAA
GCCTGTGTTATCAATTGCCAGCATTAATCATGCCCGGTTTGACTGTGGTGGTATCTCCGCTGATCTCATTAATGAAAGAT
CAGGTCGACAGCCTTATCCAAACCGGCGTCTCAGCGGCCTACTTAAACTCATCTCTGCCAAGAGAGGAGAGTCTACAAGT
CTTACAAAAGATGCGCTATGGCGAGCTAAAGTTGCTGTATGTATCGCCGGAGCGTCTACTACAAGCAAGTTTTATCGATA
GGCTACATGAGCTTAATGTCTCTTTGTTTGCGATTGACGAGGCGCACTGTATCTCGCAGTGGGGTCATGACTTTAGGCCC
GAATATGCCGCATTAGGCCGCTTACGCCAGCAATTTCCCCAAGTCCCTATCATGGCACTGACGGCGACGGCCGATAAAGC
GACCCGAGCCGACATTTGTGAGCGTTTAACCATTACGCCGCACTCTTTACTGACCAGTTTTGATCGACCCAATATTCGCT
ATACCGTAGCTGAAAAGCTCAATGCAGCGAATCAGTTGCGTCAGTTTGTCGATGCGCAAAACGGGACTAGTGGCATTGTG
TACTGTAGCAGTCGACGTCGAGTCGATGAGGTCGCAGAGCGCTTGCGTCTGCAGGGGCATCAAGCCGAAGCTTACCATGC
GGGTAAAACTCAAGAAGAGCGAGCTGATGTTCAAGACCGATTTTTAAAAGACCAGCTCGATATTGTGGTGGCAACCGTGG
CATTTGGTATGGGGATCAACAAGTCAAACGTGCGCTACGTGGTGCATTACGATATCCCTAAGAGCGTAGAGGCTTACTAC
CAAGAAACTGGTCGTGCTGGGCGAGATGGCTTAGATTCTGAAGCTCTGATGCTATTTGACCCTGCCGATATCGGTCGAGT
GCGGCACTTAATCGAGCAGTCAGAGCCTGGGCCGCAGCAACAAGTTGAGTTTCACAAGCTCAATACTATGGCTGCTTTTG
CCGAGGCGCAGACTTGCCGTCGCCAAGTGTTATTACATTATTTCGATGAACCTGCGCTAAAGGCGTGTGGTAACTGCGAT
ATTTGCCTCGACCCGCCTAAAAAATACAACGGTATTCAAGATGCACAAAAAGTGCTGTCTTGCATCTACCGGATTGGGCA
ACGTTTTGGCATTAACCACCTTATCGAAGTGCTACGTGGGTCAAAGTCGGCGAGCGTGATTGAGCGTGGGCATGACAAGT
TATCTACCTGGGGCATTGGTAAAGAGAAGAGCCACGAGCATTGGCTCAGCGTGATAAGACAGTTGATCCATCTAGGGCTT
GCCAATCAGGACATTACCCGAGGTTCTTCGGTGACGCTTAACCCATCTGCACGTGCAGTACTAAAAGGTGAAGTTGAGTT
ACTGCTTGCTGAGCCAAGAATCGTCATTCAAACCACTAAGCGCCGCAGTAATAATTCACGTGCGCCGCTTAATTACGATC
GTAAGTTGTTCGCAAGACTTAAGTTGTTGCGTCGCACGCTGGCAGAGGAGTTAGATGTGCCGCCATACTTAGTGTTTAAT
GATGCAACTTTGGCTGAAATGGCTGCAATACTACCAACCAGTCCTGGCGAGATGTTGGCTGTAAACGGCGTAGGTGAACG
CAAGTTAGAACGCTTTGGTGGTGAGTTTCTTGATGAAATAGCGGACTACCTCGCAGAAGGTTAA

Upstream 100 bases:

>100_bases
AGGATGCAAGCTCAAAATTTATTCAGTAACGACAATCGAGAGAGACAATAGCCTCACGCTCATTTAGAATAGTCGACCCT
ATTTTTAACACAGGTTCACT

Downstream 100 bases:

>100_bases
TCGATCGTTCTTAGTCTGTCATTACTTGAAATAACGGCCTTACGGTTCTTAATTACTCATTGGCACTTGTTACTGAGAGA
CGCATGCTGACCGGTTTTAG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MDQAALDNSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLPALIMPGLTVVVSPLISLMKD
QVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLYVSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRP
EYAALGRLRQQFPQVPIMALTATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGTSGIV
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERADVQDRFLKDQLDIVVATVAFGMGINKSNVRYVVHYDIPKSVEAYY
QETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQQVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCD
ICLDPPKKYNGIQDAQKVLSCIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
ANQDITRGSSVTLNPSARAVLKGEVELLLAEPRIVIQTTKRRSNNSRAPLNYDRKLFARLKLLRRTLAEELDVPPYLVFN
DATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEIADYLAEG

Sequences:

>Translated_607_residues
MDQAALDNSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLPALIMPGLTVVVSPLISLMKD
QVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLYVSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRP
EYAALGRLRQQFPQVPIMALTATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGTSGIV
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERADVQDRFLKDQLDIVVATVAFGMGINKSNVRYVVHYDIPKSVEAYY
QETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQQVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCD
ICLDPPKKYNGIQDAQKVLSCIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
ANQDITRGSSVTLNPSARAVLKGEVELLLAEPRIVIQTTKRRSNNSRAPLNYDRKLFARLKLLRRTLAEELDVPPYLVFN
DATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEIADYLAEG
>Mature_607_residues
MDQAALDNSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLPALIMPGLTVVVSPLISLMKD
QVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLYVSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRP
EYAALGRLRQQFPQVPIMALTATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGTSGIV
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERADVQDRFLKDQLDIVVATVAFGMGINKSNVRYVVHYDIPKSVEAYY
QETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQQVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCD
ICLDPPKKYNGIQDAQKVLSCIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
ANQDITRGSSVTLNPSARAVLKGEVELLLAEPRIVIQTTKRRSNNSRAPLNYDRKLFARLKLLRRTLAEELDVPPYLVFN
DATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEIADYLAEG

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=629, Percent_Identity=35.2941176470588, Blast_Score=352, Evalue=4e-97,
Organism=Homo sapiens, GI169218196, Length=502, Percent_Identity=37.0517928286853, Blast_Score=312, Evalue=5e-85,
Organism=Homo sapiens, GI110735439, Length=502, Percent_Identity=37.0517928286853, Blast_Score=312, Evalue=6e-85,
Organism=Homo sapiens, GI14591902, Length=458, Percent_Identity=38.2096069868996, Blast_Score=299, Evalue=5e-81,
Organism=Homo sapiens, GI14591904, Length=458, Percent_Identity=38.2096069868996, Blast_Score=299, Evalue=5e-81,
Organism=Homo sapiens, GI148612816, Length=424, Percent_Identity=38.2075471698113, Blast_Score=272, Evalue=6e-73,
Organism=Homo sapiens, GI51242943, Length=363, Percent_Identity=40.495867768595, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI51242947, Length=363, Percent_Identity=40.495867768595, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI284005309, Length=366, Percent_Identity=38.2513661202186, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI148613856, Length=339, Percent_Identity=25.6637168141593, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI38201710, Length=339, Percent_Identity=25.6637168141593, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4758138, Length=337, Percent_Identity=24.9258160237389, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI222352149, Length=330, Percent_Identity=21.2121212121212, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI21071032, Length=92, Percent_Identity=34.7826086956522, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI7661920, Length=346, Percent_Identity=21.0982658959538, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4758112, Length=327, Percent_Identity=25.3822629969419, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI18375623, Length=327, Percent_Identity=25.3822629969419, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994977, Length=598, Percent_Identity=57.8595317725752, Blast_Score=720, Evalue=0.0,
Organism=Escherichia coli, GI87082221, Length=339, Percent_Identity=25.9587020648968, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787016, Length=351, Percent_Identity=24.5014245014245, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788930, Length=338, Percent_Identity=24.8520710059172, Blast_Score=66, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=655, Percent_Identity=34.3511450381679, Blast_Score=334, Evalue=9e-92,
Organism=Caenorhabditis elegans, GI32564293, Length=691, Percent_Identity=30.9696092619392, Blast_Score=302, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI71987993, Length=408, Percent_Identity=38.2352941176471, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI71987997, Length=408, Percent_Identity=38.2352941176471, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17552866, Length=462, Percent_Identity=35.0649350649351, Blast_Score=257, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI17537549, Length=370, Percent_Identity=21.8918918918919, Blast_Score=82, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71987143, Length=349, Percent_Identity=22.6361031518625, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=532, Percent_Identity=36.6541353383459, Blast_Score=327, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6324217, Length=336, Percent_Identity=25.5952380952381, Blast_Score=89, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320224, Length=353, Percent_Identity=21.5297450424929, Blast_Score=84, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325138, Length=140, Percent_Identity=27.1428571428571, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324778, Length=143, Percent_Identity=28.6713286713287, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320041, Length=344, Percent_Identity=22.093023255814, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24646066, Length=633, Percent_Identity=33.175355450237, Blast_Score=337, Evalue=1e-92,
Organism=Drosophila melanogaster, GI24664226, Length=447, Percent_Identity=35.5704697986577, Blast_Score=275, Evalue=8e-74,
Organism=Drosophila melanogaster, GI24664230, Length=447, Percent_Identity=35.5704697986577, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI62472181, Length=447, Percent_Identity=35.5704697986577, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI21358123, Length=359, Percent_Identity=37.3259052924791, Blast_Score=212, Evalue=6e-55,
Organism=Drosophila melanogaster, GI28574962, Length=343, Percent_Identity=27.1137026239067, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI18857967, Length=357, Percent_Identity=25.4901960784314, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644483, Length=340, Percent_Identity=22.6470588235294, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281361218, Length=341, Percent_Identity=22.5806451612903, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644481, Length=341, Percent_Identity=22.5806451612903, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644487, Length=340, Percent_Identity=22.6470588235294, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45551833, Length=340, Percent_Identity=22.6470588235294, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644485, Length=340, Percent_Identity=22.6470588235294, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24644479, Length=341, Percent_Identity=22.5806451612903, Blast_Score=73, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355075, Length=352, Percent_Identity=20.7386363636364, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17977678, Length=344, Percent_Identity=23.8372093023256, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24645031, Length=123, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 67904; Mature: 67904

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQAALDNSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLP
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
ALIMPGLTVVVSPLISLMKDQVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
VSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRPEYAALGRLRQQFPQVPIMAL
ECHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
TATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGTSGIV
EECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCEEE
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERADVQDRFLKDQLDIVVATVAFGMGIN
EECCCCCHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSNVRYVVHYDIPKSVEAYYQETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQ
CCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHH
QVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCDICLDPPKKYNGIQDAQKVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCHHCCCHHHHHHHHH
CIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
ANQDITRGSSVTLNPSARAVLKGEVELLLAEPRIVIQTTKRRSNNSRAPLNYDRKLFARL
CCCCCCCCCCEEECCCCCEEEECCEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHH
KLLRRTLAEELDVPPYLVFNDATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEI
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
ADYLAEG
HHHHCCC
>Mature Secondary Structure
MDQAALDNSVDQLSSTLQSVFGYRTFREGQREVIEQICAGQDCLVIMPTGGGKSLCYQLP
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
ALIMPGLTVVVSPLISLMKDQVDSLIQTGVSAAYLNSSLPREESLQVLQKMRYGELKLLY
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCCEEEEE
VSPERLLQASFIDRLHELNVSLFAIDEAHCISQWGHDFRPEYAALGRLRQQFPQVPIMAL
ECHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEE
TATADKATRADICERLTITPHSLLTSFDRPNIRYTVAEKLNAANQLRQFVDAQNGTSGIV
EECCCHHHHHHHHHHCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCEEE
YCSSRRRVDEVAERLRLQGHQAEAYHAGKTQEERADVQDRFLKDQLDIVVATVAFGMGIN
EECCCCCHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KSNVRYVVHYDIPKSVEAYYQETGRAGRDGLDSEALMLFDPADIGRVRHLIEQSEPGPQQ
CCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHHHHHCCCCCCHH
QVEFHKLNTMAAFAEAQTCRRQVLLHYFDEPALKACGNCDICLDPPKKYNGIQDAQKVLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCEECCCCHHCCCHHHHHHHHH
CIYRIGQRFGINHLIEVLRGSKSASVIERGHDKLSTWGIGKEKSHEHWLSVIRQLIHLGL
HHHHHHHHCCHHHHHHHHHCCCHHHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCC
ANQDITRGSSVTLNPSARAVLKGEVELLLAEPRIVIQTTKRRSNNSRAPLNYDRKLFARL
CCCCCCCCCCEEECCCCCEEEECCEEEEEECCEEEEEECCCCCCCCCCCCCHHHHHHHHH
KLLRRTLAEELDVPPYLVFNDATLAEMAAILPTSPGEMLAVNGVGERKLERFGGEFLDEI
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
ADYLAEG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]