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The map label for this gene is phoP [H]

Identifier: 167040620

GI number: 167040620

Start: 2007343

End: 2008047

Strand: Reverse

Name: phoP [H]

Synonym: Teth514_1997

Alternate gene names: 167040620

Gene position: 2008047-2007343 (Counterclockwise)

Preceding gene: 167040621

Following gene: 167040619

Centisome position: 81.72

GC content: 32.62

Gene sequence:

>705_bases
ATGGCCCATACGGTTTTGGTTATAGAAGATGAAATTCATATATTGGAACTTTTAAGATACAACTTGGAAGCAGCAGGATA
CAAAGTTATTACTTCGGAAAATGGAAAAGAAGGCTTGGATAAAGCACTTGAAGGAAAACCTGATTTGGTTATATTAGATT
TGATGTTGCCAGATGTGGATGGACTGGAAATATGTAAAATTTTAAAAAAGAATGATGAAACGAAAAATATACCGATAATA
ATGTTAACAGCAAAAAGCGAAGAATTTGATAAAGTATTGGGATTGGAGTTGGGAGCAGATGATTATATAACAAAGCCTTT
CAGCGTAAGAGAATTGTTAGCTCGAATTAAAGCCGTTCTTCGGCGAACCCAACAACCAGATGAAGAAAAAGAAGGAATAA
TAAAATTTGGTGATATAGTTATAGATACTGGAAAGCATTTGGTTTATAAAAAAGGAAAAGTCCTAGAATTGACTTTAAAA
GAGTTTGAGCTTTTAAAACTTTTGTCTCAAAATATGGGTAAAGTATTAACTAGAGACTATCTTTTAGACAAAGTATGGGG
ATATGAATATGCTGGAGAAACTCGAACTGTTGATGTACACATCAGGCATTTAAGAAAGAAAATAGAAGACGATGATAAAT
CCCCTGTATATATTGAAACTGTAAGAGGAATTGGGTATAAGTTAAATGATAAAGGTGAAGCGTAA

Upstream 100 bases:

>100_bases
ACGAACTTAAGAAACTTCTTAAAGAGAGTGAGACAAAAAAAGAAAATGCATAACTTTTTGCTTCAAAGGTGTACAAGCCA
TATTATCTGGAGGTGTCAAA

Downstream 100 bases:

>100_bases
TGTTGAAAAAATCCTATTGTAAATTGTTTTTTATAAACCTACTTGGAATTTTAATAGTCGCCATATTTTTTTTAGGCTAT
GTTCCAATGACTAAATTTAT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAHTVLVIEDEIHILELLRYNLEAAGYKVITSENGKEGLDKALEGKPDLVILDLMLPDVDGLEICKILKKNDETKNIPII
MLTAKSEEFDKVLGLELGADDYITKPFSVRELLARIKAVLRRTQQPDEEKEGIIKFGDIVIDTGKHLVYKKGKVLELTLK
EFELLKLLSQNMGKVLTRDYLLDKVWGYEYAGETRTVDVHIRHLRKKIEDDDKSPVYIETVRGIGYKLNDKGEA

Sequences:

>Translated_234_residues
MAHTVLVIEDEIHILELLRYNLEAAGYKVITSENGKEGLDKALEGKPDLVILDLMLPDVDGLEICKILKKNDETKNIPII
MLTAKSEEFDKVLGLELGADDYITKPFSVRELLARIKAVLRRTQQPDEEKEGIIKFGDIVIDTGKHLVYKKGKVLELTLK
EFELLKLLSQNMGKVLTRDYLLDKVWGYEYAGETRTVDVHIRHLRKKIEDDDKSPVYIETVRGIGYKLNDKGEA
>Mature_233_residues
AHTVLVIEDEIHILELLRYNLEAAGYKVITSENGKEGLDKALEGKPDLVILDLMLPDVDGLEICKILKKNDETKNIPIIM
LTAKSEEFDKVLGLELGADDYITKPFSVRELLARIKAVLRRTQQPDEEKEGIIKFGDIVIDTGKHLVYKKGKVLELTLKE
FELLKLLSQNMGKVLTRDYLLDKVWGYEYAGETRTVDVHIRHLRKKIEDDDKSPVYIETVRGIGYKLNDKGEA

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=42.4242424242424, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=41.7391304347826, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=42.152466367713, Blast_Score=174, Evalue=4e-45,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=40.7894736842105, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=40.625, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=42.1739130434783, Blast_Score=158, Evalue=3e-40,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=39.2070484581498, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=38.3928571428571, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=36.4035087719298, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=36.9565217391304, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=35.2422907488987, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=36.036036036036, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787229, Length=234, Percent_Identity=32.9059829059829, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=33.0472103004292, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=31.4814814814815, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=30.3703703703704, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=26.271186440678, Blast_Score=60, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26662; Mature: 26531

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTVLVIEDEIHILELLRYNLEAAGYKVITSENGKEGLDKALEGKPDLVILDLMLPDVD
CCEEEEEEECCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEEECCCCC
GLEICKILKKNDETKNIPIIMLTAKSEEFDKVLGLELGADDYITKPFSVRELLARIKAVL
HHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHH
RRTQQPDEEKEGIIKFGDIVIDTGKHLVYKKGKVLELTLKEFELLKLLSQNMGKVLTRDY
HHCCCCCHHHCCEEEECCEEEECCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
LLDKVWGYEYAGETRTVDVHIRHLRKKIEDDDKSPVYIETVRGIGYKLNDKGEA
HHHHHCCCEECCCCEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCC
>Mature Secondary Structure 
AHTVLVIEDEIHILELLRYNLEAAGYKVITSENGKEGLDKALEGKPDLVILDLMLPDVD
CEEEEEEECCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCCCEEEEEEECCCCC
GLEICKILKKNDETKNIPIIMLTAKSEEFDKVLGLELGADDYITKPFSVRELLARIKAVL
HHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCEECCCCCCCCCHHHHHHHHHHHHHH
RRTQQPDEEKEGIIKFGDIVIDTGKHLVYKKGKVLELTLKEFELLKLLSQNMGKVLTRDY
HHCCCCCHHHCCEEEECCEEEECCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
LLDKVWGYEYAGETRTVDVHIRHLRKKIEDDDKSPVYIETVRGIGYKLNDKGEA
HHHHHCCCEECCCCEEEEHHHHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]