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The map label for this gene is potC

Identifier: 16273255

GI number: 16273255

Start: 1421416

End: 1422159

Strand: Reverse

Name: potC

Synonym: HI1345

Alternate gene names: 16273255

Gene position: 1422159-1421416 (Counterclockwise)

Preceding gene: 16273256

Following gene: 16273254

Centisome position: 77.71

GC content: 36.69

Gene sequence:

>744_bases
ATGTTTGTGGTATACGCTTATTTGTATATCCCAATTATTATTTTAGTCACTAATTCCTTTAACAAAGATCGTTATGGTTT
GAGTTGGAAAGGTTTTAGCTGGAACTGGTACGAGCGTTTATTTAATAACGACACCTTAATACAAGCTGCGATTCATTCGG
TAACTATTGCATTTTTTGCGGCTACCCTAGCTACTATTGTAGGTGGATTAACTGCAATCGCACTTTATCGCTATCGATTC
CGCGGTAAACAAGCAGTAAGCGGTATGCTATTTATCGTTATGATGTCTCCAGATATTGTAATGGCAGTATCTTTACTTGC
ATTATTTATGGTTGTGGGTATTTCATTGGGCTTCTGGTCTTTACTACTTGCCCACGTAACTTTCTGTTTACCGTATGTGA
CCGTAACTATCTTCTCTCGCTTAAATGGCTTTGATTCCAGAATGTTAGAAGCGGCGAAAGACTTAGGTGCAAGCGAAGTG
ACTATTTTACGTAAAATTATCCTTCCTTTAGCATTACCTGCAGTTGTATCTGGTTGGTTATTAAGTTTCACTATTTCATT
AGATGATGTTGTGGTTTCATCATTTGTCAGTGGTGTAAGTTATGAAATCTTACCATTGAGAATATTCTCTCTAGTGAAAA
CTGGTGTAACACCTGAAGTTAATGCTTTAGCAACGATTATGATCGTGCTTTCATTAGCTCTTGTCGTTTTAAGCCAGCTA
ATTACACGAAAAAATAACCATTAA

Upstream 100 bases:

>100_bases
GTTCTAATGGCATTGTTGATTTTCGTGTACTACCGCGCGAATAAACTATTGAATAGGAAAGTGGAGTTAGAATAATGAGT
CGTTTCTACGTAATGCATTT

Downstream 100 bases:

>100_bases
TTAACAAAAGGTTTCACAAACCTTTGAATTTAAAATAGAATACGCCTTGACGCACAATCAAGGCGTTTTTTTATGCCTGT
CATTCGGCAGGTGGTTTTTT

Product: spermidine/putrescine ABC transporter membrane protein

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MFVVYAYLYIPIIILVTNSFNKDRYGLSWKGFSWNWYERLFNNDTLIQAAIHSVTIAFFAATLATIVGGLTAIALYRYRF
RGKQAVSGMLFIVMMSPDIVMAVSLLALFMVVGISLGFWSLLLAHVTFCLPYVTVTIFSRLNGFDSRMLEAAKDLGASEV
TILRKIILPLALPAVVSGWLLSFTISLDDVVVSSFVSGVSYEILPLRIFSLVKTGVTPEVNALATIMIVLSLALVVLSQL
ITRKNNH

Sequences:

>Translated_247_residues
MFVVYAYLYIPIIILVTNSFNKDRYGLSWKGFSWNWYERLFNNDTLIQAAIHSVTIAFFAATLATIVGGLTAIALYRYRF
RGKQAVSGMLFIVMMSPDIVMAVSLLALFMVVGISLGFWSLLLAHVTFCLPYVTVTIFSRLNGFDSRMLEAAKDLGASEV
TILRKIILPLALPAVVSGWLLSFTISLDDVVVSSFVSGVSYEILPLRIFSLVKTGVTPEVNALATIMIVLSLALVVLSQL
ITRKNNH
>Mature_247_residues
MFVVYAYLYIPIIILVTNSFNKDRYGLSWKGFSWNWYERLFNNDTLIQAAIHSVTIAFFAATLATIVGGLTAIALYRYRF
RGKQAVSGMLFIVMMSPDIVMAVSLLALFMVVGISLGFWSLLLAHVTFCLPYVTVTIFSRLNGFDSRMLEAAKDLGASEV
TILRKIILPLALPAVVSGWLLSFTISLDDVVVSSFVSGVSYEILPLRIFSLVKTGVTPEVNALATIMIVLSLALVVLSQL
ITRKNNH

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787368, Length=247, Percent_Identity=71.2550607287449, Blast_Score=352, Evalue=1e-98,
Organism=Escherichia coli, GI1787081, Length=231, Percent_Identity=43.2900432900433, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI1787714, Length=244, Percent_Identity=27.4590163934426, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788764, Length=211, Percent_Identity=27.9620853080569, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): POTC_HAEIN (P45169)

Other databases:

- EMBL:   L42023
- PIR:   I64117
- RefSeq:   NP_439496.1
- ProteinModelPortal:   P45169
- SMR:   P45169
- GeneID:   950267
- GenomeReviews:   L42023_GR
- KEGG:   hin:HI1345
- NMPDR:   fig|71421.1.peg.1281
- TIGR:   HI_1345
- HOGENOM:   HBG685300
- ProtClustDB:   PRK09500
- BioCyc:   HINF71421:HI_1345-MONOMER
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 27344; Mature: 27344

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdac52e4)-; HASH(0xd9bf85c)-; HASH(0xe34a594)-; HASH(0xe2e0ce4)-; HASH(0xe7e9430)-; HASH(0xe7599bc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCH
>Mature Secondary Structure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HHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800