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The map label for this gene is surA [H]

Identifier: 162149098

GI number: 162149098

Start: 3420765

End: 3422144

Strand: Direct

Name: surA [H]

Synonym: GDI_3328

Alternate gene names: 162149098

Gene position: 3420765-3422144 (Clockwise)

Preceding gene: 162149097

Following gene: 162149099

Centisome position: 86.73

GC content: 67.25

Gene sequence:

>1380_bases
ATGCGTGAGAGACCGAGCAGAATGCGACGCCGCCCCACCAAGACCGGTTTTTCCTCGAATGTCATGGCATGCCTGCTGGC
GGCCGGGCTGGCGGCCGTCGCCGGCGGCCCGGCGCTGGCCGCCCGCCATGCGCCCCCCCCCGCTTCCGCCCATTCATCCG
ACCAGTCGGACGCGACGAGCCAGGATGCGATCATCGCCATCATCGACGGCACGCTGCTGACCCGCCGGGACGTGGACAAT
CGCGGACGGCTGTTCGCGCTGTCGGCGGGCCTGACGCTCAGCGACGACGTCATGGCCCGGCTGCGGCCGCAGATCCTCCG
GCAGCTGATCGACGAGCGCCTGCGGCAGAACGAGATGCTCTCGCGCCACATCAACGTGTCGCCCGACCAGATCGCCGCCT
CGATCGCCGACATCGAACGCCGGAACGGCATGCCGAAGAACGCCCTGCGCGACCGGCTGGCCCAGGACGGAATTTCGCTG
ACCACCATGATCGACCAGATCCGCGTGCAACTGGGCTGGTCGCAGGTGCTGCGCGAGGAAATGGGAACCCGCGGCCGCAT
CACCGCGGCCGAGATCTCCCAGCGCGAGGAGGCCCTGCGGCACGAGGACGGCAAGCCGCAATACCTGATCAGCGAAATCT
TCATCCCGGTCGACGATCCCCGCCATTCCGAGGACGAGCTGAAATTCACCCAGACCATCATCCAGGAACTGCGCAACGGC
GCGCCGTTCCCCATCGTGGCGGCCCAGTTCTCGCAGAACCAGGCGGCGCTCGAAGGCGGATTGATGGGCTGGGTGCAGGA
GGACAGCCTGGACCCGCAGGTCGTCGAAATCGCCAAGGCCATGCCGCCCGGCGCCATTTCCAACCCGATCCGCGTCGCGG
GCGGCTATGTCATCGCGACGCTGAACGGCCGCCGCGTGATCGGTCACCAGATGGGCACGCTGGTGTCGCTGCGCGAGGCG
TTCATTCCCTTCACCACGCCCCTGGACCCGCAGGCGCCGAGCGAGCAGCAGCGCGATGCGCTGAAGCAGGCGCAGCAGAT
TTCCACGACCGTGCATTCGTGCCCGGAGCTTGAGGCGATCAACCACAAATTCGGCGACAAGCACCCGTCCAATCCGGGCG
ACGTGCAGCTCGAACGCGTCAACGAGCAGATGCAGAAGGTCCTGACCGGCCTGACCCCGGGCCAGGCCAGCCATCCGCTG
GTGGCCCCCGACGGTATCGCGGTGCTGATGGTCTGCTCCCGCCAGCAGAAGAACTTCGCCCAGCAGACCCCCAGCGACAT
CGCCGACCAGCTGATGAACGAACGGGCGGAACAGACGTCGCGCCAGCTGGATCGCGACCTGCATCGCCGCGCCATCATCG
AAATGCGCTCGAAGGTATGA

Upstream 100 bases:

>100_bases
AAGCAATATACGTCGATCGGCGGCCAACAGCGCAATTCGACCATCATGTTCACCCTGACCTTCAAGACCATCGGTGCCTT
TGGTATTCGTGGCTGATCCG

Downstream 100 bases:

>100_bases
GGCAGCCGCTCTGACCACTCCACCCCTGCCCGGTAGCCAGCCGTTGCTGGAACCGCTGCGCGACGTGATCGCCCGCCACG
GGCTGGATGCGCGCAAGGCC

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRERPSRMRRRPTKTGFSSNVMACLLAAGLAAVAGGPALAARHAPPPASAHSSDQSDATSQDAIIAIIDGTLLTRRDVDN
RGRLFALSAGLTLSDDVMARLRPQILRQLIDERLRQNEMLSRHINVSPDQIAASIADIERRNGMPKNALRDRLAQDGISL
TTMIDQIRVQLGWSQVLREEMGTRGRITAAEISQREEALRHEDGKPQYLISEIFIPVDDPRHSEDELKFTQTIIQELRNG
APFPIVAAQFSQNQAALEGGLMGWVQEDSLDPQVVEIAKAMPPGAISNPIRVAGGYVIATLNGRRVIGHQMGTLVSLREA
FIPFTTPLDPQAPSEQQRDALKQAQQISTTVHSCPELEAINHKFGDKHPSNPGDVQLERVNEQMQKVLTGLTPGQASHPL
VAPDGIAVLMVCSRQQKNFAQQTPSDIADQLMNERAEQTSRQLDRDLHRRAIIEMRSKV

Sequences:

>Translated_459_residues
MRERPSRMRRRPTKTGFSSNVMACLLAAGLAAVAGGPALAARHAPPPASAHSSDQSDATSQDAIIAIIDGTLLTRRDVDN
RGRLFALSAGLTLSDDVMARLRPQILRQLIDERLRQNEMLSRHINVSPDQIAASIADIERRNGMPKNALRDRLAQDGISL
TTMIDQIRVQLGWSQVLREEMGTRGRITAAEISQREEALRHEDGKPQYLISEIFIPVDDPRHSEDELKFTQTIIQELRNG
APFPIVAAQFSQNQAALEGGLMGWVQEDSLDPQVVEIAKAMPPGAISNPIRVAGGYVIATLNGRRVIGHQMGTLVSLREA
FIPFTTPLDPQAPSEQQRDALKQAQQISTTVHSCPELEAINHKFGDKHPSNPGDVQLERVNEQMQKVLTGLTPGQASHPL
VAPDGIAVLMVCSRQQKNFAQQTPSDIADQLMNERAEQTSRQLDRDLHRRAIIEMRSKV
>Mature_459_residues
MRERPSRMRRRPTKTGFSSNVMACLLAAGLAAVAGGPALAARHAPPPASAHSSDQSDATSQDAIIAIIDGTLLTRRDVDN
RGRLFALSAGLTLSDDVMARLRPQILRQLIDERLRQNEMLSRHINVSPDQIAASIADIERRNGMPKNALRDRLAQDGISL
TTMIDQIRVQLGWSQVLREEMGTRGRITAAEISQREEALRHEDGKPQYLISEIFIPVDDPRHSEDELKFTQTIIQELRNG
APFPIVAAQFSQNQAALEGGLMGWVQEDSLDPQVVEIAKAMPPGAISNPIRVAGGYVIATLNGRRVIGHQMGTLVSLREA
FIPFTTPLDPQAPSEQQRDALKQAQQISTTVHSCPELEAINHKFGDKHPSNPGDVQLERVNEQMQKVLTGLTPGQASHPL
VAPDGIAVLMVCSRQQKNFAQQTPSDIADQLMNERAEQTSRQLDRDLHRRAIIEMRSKV

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=229, Percent_Identity=30.5676855895196, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 50594; Mature: 50594

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRERPSRMRRRPTKTGFSSNVMACLLAAGLAAVAGGPALAARHAPPPASAHSSDQSDATS
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCC
QDAIIAIIDGTLLTRRDVDNRGRLFALSAGLTLSDDVMARLRPQILRQLIDERLRQNEML
CCCEEEEECCCEEECCCCCCCCCEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
SRHINVSPDQIAASIADIERRNGMPKNALRDRLAQDGISLTTMIDQIRVQLGWSQVLREE
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
MGTRGRITAAEISQREEALRHEDGKPQYLISEIFIPVDDPRHSEDELKFTQTIIQELRNG
HCCCCCEEHHHHHHHHHHHHCCCCCCCEEHHHHEEECCCCCCCHHHHHHHHHHHHHHHCC
APFPIVAAQFSQNQAALEGGLMGWVQEDSLDPQVVEIAKAMPPGAISNPIRVAGGYVIAT
CCCCEEEHHHCCCHHHHHCCHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCEEEEE
LNGRRVIGHQMGTLVSLREAFIPFTTPLDPQAPSEQQRDALKQAQQISTTVHSCPELEAI
ECCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
NHKFGDKHPSNPGDVQLERVNEQMQKVLTGLTPGQASHPLVAPDGIAVLMVCSRQQKNFA
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QQTPSDIADQLMNERAEQTSRQLDRDLHRRAIIEMRSKV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRERPSRMRRRPTKTGFSSNVMACLLAAGLAAVAGGPALAARHAPPPASAHSSDQSDATS
CCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCC
QDAIIAIIDGTLLTRRDVDNRGRLFALSAGLTLSDDVMARLRPQILRQLIDERLRQNEML
CCCEEEEECCCEEECCCCCCCCCEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
SRHINVSPDQIAASIADIERRNGMPKNALRDRLAQDGISLTTMIDQIRVQLGWSQVLREE
HHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHH
MGTRGRITAAEISQREEALRHEDGKPQYLISEIFIPVDDPRHSEDELKFTQTIIQELRNG
HCCCCCEEHHHHHHHHHHHHCCCCCCCEEHHHHEEECCCCCCCHHHHHHHHHHHHHHHCC
APFPIVAAQFSQNQAALEGGLMGWVQEDSLDPQVVEIAKAMPPGAISNPIRVAGGYVIAT
CCCCEEEHHHCCCHHHHHCCHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEEEECCEEEEE
LNGRRVIGHQMGTLVSLREAFIPFTTPLDPQAPSEQQRDALKQAQQISTTVHSCPELEAI
ECCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
NHKFGDKHPSNPGDVQLERVNEQMQKVLTGLTPGQASHPLVAPDGIAVLMVCSRQQKNFA
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QQTPSDIADQLMNERAEQTSRQLDRDLHRRAIIEMRSKV
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]