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The map label for this gene is nuoC [H]

Identifier: 161870821

GI number: 161870821

Start: 1953617

End: 1954210

Strand: Reverse

Name: nuoC [H]

Synonym: NMCC_1903

Alternate gene names: 161870821

Gene position: 1954210-1953617 (Counterclockwise)

Preceding gene: 161870822

Following gene: 161870820

Centisome position: 90.75

GC content: 51.52

Gene sequence:

>594_bases
ATGGCAAGCATTCAAAACTTATACGAGACCGTTGTCGGCGTGCTTGGCGATCAGGCAAGCAAAGTCATTTCTGCTTTGGG
CGAGATTACCGTTGAGTGTCTGCCCGAACACTATATTTCAGTCATGACCGCATTGCGCGACCATGAAGAGTTGCATTTCG
AGCTTCTGGTCGACTTGTGCGGTGTCGATTACAGCACTTACAAAAACGAAGTATGGCAGGGCAAACGCTTTGCCGTCGTC
AGTCAGTTGCTTTCCGTTAAAAACAATCAACGCATCCGCGTACGCGTCTGGGTTTCAGACGACGACTTCCCCGTAGTCGA
ATCCGTAGTTCCCGTTTACAACAGCGCGGATTGGTACGAGCGCGAAGCCTTCGATTTGTACGGCATCATGTTCAACAACC
ATCCCGACTTGCGCCGCATCCTGACCGATTACGGCTTTGTCGGACATCCGTTCCGCAAAGACTTCCCGATTTCCGGCTAT
GTGGAAATGCGTTACGACGAAGAGCAAAAACGCGTGATTTACCAACCTGTTACCATTGAGCCGCGCGAGATCACGCCGCG
TATCGTCCGTGAGGAGAACTACGGTGGCCAATAA

Upstream 100 bases:

>100_bases
TCCGCCGACTGCGGAAGCCCTGATTTACGGCCTGATTCAGCTCCAACAAAAAATCAAGCGCACTTCCACCATCGCGCGTG
ACGAGTAAGGAGAGGACGAT

Downstream 100 bases:

>100_bases
ATTAAGAAACTACACCATCAACTTCGGCCCGCAACACCCTGCGGCGCACGGCGTATTGCGTATGATTTTGGAGTTGGAAG
GCGAAACCATCGTCCGTGCC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MASIQNLYETVVGVLGDQASKVISALGEITVECLPEHYISVMTALRDHEELHFELLVDLCGVDYSTYKNEVWQGKRFAVV
SQLLSVKNNQRIRVRVWVSDDDFPVVESVVPVYNSADWYEREAFDLYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGY
VEMRYDEEQKRVIYQPVTIEPREITPRIVREENYGGQ

Sequences:

>Translated_197_residues
MASIQNLYETVVGVLGDQASKVISALGEITVECLPEHYISVMTALRDHEELHFELLVDLCGVDYSTYKNEVWQGKRFAVV
SQLLSVKNNQRIRVRVWVSDDDFPVVESVVPVYNSADWYEREAFDLYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGY
VEMRYDEEQKRVIYQPVTIEPREITPRIVREENYGGQ
>Mature_196_residues
ASIQNLYETVVGVLGDQASKVISALGEITVECLPEHYISVMTALRDHEELHFELLVDLCGVDYSTYKNEVWQGKRFAVVS
QLLSVKNNQRIRVRVWVSDDDFPVVESVVPVYNSADWYEREAFDLYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGYV
EMRYDEEQKRVIYQPVTIEPREITPRIVREENYGGQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=157, Percent_Identity=52.2292993630573, Blast_Score=167, Evalue=5e-42,
Organism=Escherichia coli, GI145693162, Length=132, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=174, Percent_Identity=44.2528735632184, Blast_Score=149, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71990788, Length=154, Percent_Identity=46.7532467532467, Blast_Score=149, Evalue=7e-37,
Organism=Drosophila melanogaster, GI24656494, Length=157, Percent_Identity=49.0445859872611, Blast_Score=158, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 22928; Mature: 22797

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIQNLYETVVGVLGDQASKVISALGEITVECLPEHYISVMTALRDHEELHFELLVDLC
CCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVDYSTYKNEVWQGKRFAVVSQLLSVKNNQRIRVRVWVSDDDFPVVESVVPVYNSADWYE
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCHH
REAFDLYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGYVEMRYDEEQKRVIYQPVTIE
HHHHHEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
PREITPRIVREENYGGQ
CHHCCHHHEECCCCCCC
>Mature Secondary Structure 
ASIQNLYETVVGVLGDQASKVISALGEITVECLPEHYISVMTALRDHEELHFELLVDLC
CHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVDYSTYKNEVWQGKRFAVVSQLLSVKNNQRIRVRVWVSDDDFPVVESVVPVYNSADWYE
CCCHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCCHH
REAFDLYGIMFNNHPDLRRILTDYGFVGHPFRKDFPISGYVEMRYDEEQKRVIYQPVTIE
HHHHHEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
PREITPRIVREENYGGQ
CHHCCHHHEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA