Click here to switch to the map view.

The map label for this gene is nuoB [H]

Identifier: 161870822

GI number: 161870822

Start: 1954330

End: 1954704

Strand: Reverse

Name: nuoB [H]

Synonym: NMCC_1904

Alternate gene names: 161870822

Gene position: 1954704-1954330 (Counterclockwise)

Preceding gene: 161870823

Following gene: 161870821

Centisome position: 90.77

GC content: 57.87

Gene sequence:

>375_bases
ATGGGAATAGAAGGCGTTTTGAAAAAAGGTTTCATCACCACCAGCGCGGATACGGTGTTGAACTATATGCGTACCGGTTC
GTTGTGGCCGGTTACTTTCGGCTTGGCCTGCTGCGCCGTGGAAATGATGCACGCGGGTATGGCGCGTTATGACCTTGACC
GTTTCGGCATCATTTTCCGTCCGTCCCCACGTCAGGCCGACCTGATGATTGTGCGGGGTACGCTGACCAACAAAATGGCA
CCCGCCCTGCGCCGCGTGTATGACCAGCTCGCCGAGCCGCGCTGGGTATTGTCTATGGGCTCGTGTGCCAACGGCGGCGG
CTATTATCACTATTCTTATTCCGTTGTGCGCGGTGCCGACCGCGTCGTGCGGTAG

Upstream 100 bases:

>100_bases
TGTTCAAAGATTTGGGCGCGTACGGCTTCTGGTCTATGCTGGTGTTTATCGTCGTTCTGACGGTAGGCTTTGTTTACGAA
TGGAAAAAAGGTGCGCTGGA

Downstream 100 bases:

>100_bases
ACGTTTATGTGCCGGGTTGTCCGCCGACTGCGGAAGCCCTGATTTACGGCCTGATTCAGCTCCAACAAAAAATCAAGCGC
ACTTCCACCATCGCGCGTGA

Product: NADH dehydrogenase I chain B

Products: NA

Alternate protein names: NADH dehydrogenase I subunit B; NDH-1 subunit B [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MGIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMHAGMARYDLDRFGIIFRPSPRQADLMIVRGTLTNKMA
PALRRVYDQLAEPRWVLSMGSCANGGGYYHYSYSVVRGADRVVR

Sequences:

>Translated_124_residues
MGIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMHAGMARYDLDRFGIIFRPSPRQADLMIVRGTLTNKMA
PALRRVYDQLAEPRWVLSMGSCANGGGYYHYSYSVVRGADRVVR
>Mature_123_residues
GIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMHAGMARYDLDRFGIIFRPSPRQADLMIVRGTLTNKMAP
ALRRVYDQLAEPRWVLSMGSCANGGGYYHYSYSVVRGADRVVR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG0377

COG function: function code C; NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 20 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI187281616, Length=113, Percent_Identity=71.6814159292035, Blast_Score=185, Evalue=9e-48,
Organism=Escherichia coli, GI1788624, Length=122, Percent_Identity=48.3606557377049, Blast_Score=125, Evalue=6e-31,
Organism=Escherichia coli, GI1789074, Length=91, Percent_Identity=37.3626373626374, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1788834, Length=91, Percent_Identity=38.4615384615385, Blast_Score=62, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17509685, Length=116, Percent_Identity=67.2413793103448, Blast_Score=179, Evalue=3e-46,
Organism=Drosophila melanogaster, GI18859983, Length=107, Percent_Identity=75.7009345794392, Blast_Score=189, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24642371, Length=107, Percent_Identity=75.7009345794392, Blast_Score=189, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24651058, Length=107, Percent_Identity=75.7009345794392, Blast_Score=185, Evalue=5e-48,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006137
- InterPro:   IPR006138
- InterPro:   IPR014406 [H]

Pfam domain/function: PF01058 Oxidored_q6 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13804; Mature: 13673

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMHAGMARYDLDRFGIIFR
CCCCHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHCCEEEC
PSPRQADLMIVRGTLTNKMAPALRRVYDQLAEPRWVLSMGSCANGGGYYHYSYSVVRGAD
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEHHHHHCHH
RVVR
HHCC
>Mature Secondary Structure 
GIEGVLKKGFITTSADTVLNYMRTGSLWPVTFGLACCAVEMMHAGMARYDLDRFGIIFR
CCCHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHCCEEEC
PSPRQADLMIVRGTLTNKMAPALRRVYDQLAEPRWVLSMGSCANGGGYYHYSYSVVRGAD
CCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEHHHHHCHH
RVVR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA