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The map label for this gene is nuoE [H]

Identifier: 161870819

GI number: 161870819

Start: 1951341

End: 1951814

Strand: Reverse

Name: nuoE [H]

Synonym: NMCC_1901

Alternate gene names: 161870819

Gene position: 1951814-1951341 (Counterclockwise)

Preceding gene: 161870820

Following gene: 161870818

Centisome position: 90.64

GC content: 53.16

Gene sequence:

>474_bases
ATGTTATCCACAGAATCCTTAAAACAAATCGACATAGAGTTGGCGAAATATCCTGCCGACCAACGCCGATCCGCCATTAT
GGGCGCATTGCGTATTGCCCAGACCGAAAAAGGCTGGCTTGCTCCCGAGACCATCGCCTTTGTCGCAGACTACATCGGCA
TATCGCCTGCACAAGCCTACGAAGTCGCTACCTTCTACAATATGTACGATCTTGAGCCTGTCGGCAAATACAAACTGACC
GTTTGTACCAACCTGCCCTGCGCCCTGCGCGGTGGTATGGCTACCGGCGAATACCTCAAACAAAGACTCGGTATCGGCTA
CGGCGAAATCACGCCCGACGGCAAATTTACCCTTGTCGAAGGCGAATGCATGGGCGCGTGCGGCGATGCCCCCGTTATGC
TGGTCAACAACCACAGCATGTGCAGCTTTATGACTGAAGAGGCGATTGAGAAGAAACTGGCGGAGTTGGAGTAG

Upstream 100 bases:

>100_bases
CCGTAGTGAAATCATTTACAAAACGAAGAGTGGATTTAACCGTTTAAATTTGTTTTCAGGCTGCCTGAAATTCCAAAAAA
ACCTAATTTAGGATTACAAG

Downstream 100 bases:

>100_bases
GTCGTCTGAAACGACGATTTAAACGTAGGTCGGATACTTGTATCCGACAGAGTGGGTAAAAAGGCAAAATGTCGGATTTA
AGAATCCGCCCTACTGAAAT

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I chain 2; NDH-1 subunit 2 [H]

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MLSTESLKQIDIELAKYPADQRRSAIMGALRIAQTEKGWLAPETIAFVADYIGISPAQAYEVATFYNMYDLEPVGKYKLT
VCTNLPCALRGGMATGEYLKQRLGIGYGEITPDGKFTLVEGECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE

Sequences:

>Translated_157_residues
MLSTESLKQIDIELAKYPADQRRSAIMGALRIAQTEKGWLAPETIAFVADYIGISPAQAYEVATFYNMYDLEPVGKYKLT
VCTNLPCALRGGMATGEYLKQRLGIGYGEITPDGKFTLVEGECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE
>Mature_157_residues
MLSTESLKQIDIELAKYPADQRRSAIMGALRIAQTEKGWLAPETIAFVADYIGISPAQAYEVATFYNMYDLEPVGKYKLT
VCTNLPCALRGGMATGEYLKQRLGIGYGEITPDGKFTLVEGECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=156, Percent_Identity=39.7435897435897, Blast_Score=128, Evalue=2e-30,
Organism=Escherichia coli, GI1788621, Length=152, Percent_Identity=32.2368421052632, Blast_Score=88, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561328, Length=136, Percent_Identity=41.1764705882353, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21355353, Length=155, Percent_Identity=41.2903225806452, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI18859877, Length=136, Percent_Identity=41.1764705882353, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17203; Mature: 17203

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTESLKQIDIELAKYPADQRRSAIMGALRIAQTEKGWLAPETIAFVADYIGISPAQAY
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHH
EVATFYNMYDLEPVGKYKLTVCTNLPCALRGGMATGEYLKQRLGIGYGEITPDGKFTLVE
HHHHHHCCCCCCCCCCEEEEEECCCCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEE
GECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSTESLKQIDIELAKYPADQRRSAIMGALRIAQTEKGWLAPETIAFVADYIGISPAQAY
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHH
EVATFYNMYDLEPVGKYKLTVCTNLPCALRGGMATGEYLKQRLGIGYGEITPDGKFTLVE
HHHHHHCCCCCCCCCCEEEEEECCCCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEE
GECMGACGDAPVMLVNNHSMCSFMTEEAIEKKLAELE
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020134 [H]