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The map label for this gene is nuoF [H]

Identifier: 161870818

GI number: 161870818

Start: 1949651

End: 1950952

Strand: Reverse

Name: nuoF [H]

Synonym: NMCC_1900

Alternate gene names: 161870818

Gene position: 1950952-1949651 (Counterclockwise)

Preceding gene: 161870819

Following gene: 161870817

Centisome position: 90.6

GC content: 52.69

Gene sequence:

>1302_bases
ATGGCTATTTACCAATCAGGCGTGATTTTTGACCAAGTGGATACCGCCAATCCCGATTGTTGGACATTGGACGAATACGT
CAAACGTGGCGGTTATACCGCCCTGCGTAAAATCCTGTCCGAAAACATCTCGCAAACCGATGTGATTGATGAAGTCAAAA
CCTCCGGCTTGCGCGGGCGTGGCGGTGCGGGCTTCCCGACCGGTTTGAAATGGAGCTTTATGCCCCGTTCCTTCCCGGGC
GAAAAATATGTGGTTTGCAACACCGACGAAGGCGAGCCGGGTACATTTAAAGACCGCGACATCATCATGTTCAATCCTCA
TGCCCTGATTGAAGGCATGATTATTGCCGGTTACGCGATGGGCGCAAAAGCGGGCTACAACTATATCCACGGCGAAATTT
TCGAAGGCTATCAACGCTTTGAGACCGCTTTGGCGCAGGCGCGTGCCGCAGGCTTTTTGGGTAAAAATATTTTAGGCTCG
GATTTTGAATTTGAACTCTTCGCCCACCACGGCTACGGCGCATATATTTGCGGCGAAGAAACCGCATTGCTCGAATCGCT
GGAAGGCAAAAAAGGCCAGCCGCGCTTTAAACCGCCATTCCCTGCTTCGTTCGGCCTGTACGGCAAACCGACTACCATCA
ACAATACCGAAACGTTCTCCTCCGTTCCATTCATTATCCGTGACGGCGGACAGGCGTTTGCCGATAAAGGTATTCCGAAT
GCAGGCGGTACCAAATTATTCTGTATTTCCGGCCATGTCGAGCGTCCGGGCAACTATGAAGTGCCATTGGGCACGCCGTT
TGCCGAAGTCCTGAAAATGGCAGGCGGTATGCGCGGCGGTAAAAAACTCAAAGCCGTTATTCCCGGCGGTTCGTCCGCGC
CCGTGTTGCCTGCCGATATCATGATGCAGACCAATATGGACTATGACTCGATTTCCAAAGCAGGCTCGATGTTGGGTTCC
GGCGCGATTATCGTCATGGACGAAGACGTGTGCATGGTGAAAGCTCTCGAACGGTTAAGCTACTTCTACTACGACGAGTC
TTGCGGCCAATGTACCCCCTGCCGCGAAGGTACCGGCTGGCTTTACCGCATCGTCCACCGCATCGTAGAAGGCAAAGGCT
GTATGGAAGACTTGGATTTGCTGGATTCTATCGGTAACCAAATGGCAGGCCGCACCATCTGCGCCCTTGCCGATGCCGCT
GTTTTCCCTGTTCGCAGCTTTACCAAGCATTTCCGTGATGAGTTTGTGTATTACATCGAACACGGCGGGCCGATGAAAGA
GCATAAGTGGGGAGGGTGGTAA

Upstream 100 bases:

>100_bases
ATTTTATTTCAGACGACGTTACAAGCCGGTACACAAAGACATCTTAAGGTCGTCTGAAACAGAGGCCGCAACCGATACGA
AAACGAATAGGCACACCAAA

Downstream 100 bases:

>100_bases
TGGCAGAAAAGAATTATTTTGGCTACCCTTGTGATGATTGGGAAGCAGCTAAACTAGAAGCAAAGAAATATTTGATTGAG
AAAGTTGCGAAACTAGGCAA

Product: NADH dehydrogenase I chain F

Products: NA

Alternate protein names: NADH dehydrogenase I subunit F 2; NDH-1 subunit F 2 [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MAIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENISQTDVIDEVKTSGLRGRGGAGFPTGLKWSFMPRSFPG
EKYVVCNTDEGEPGTFKDRDIIMFNPHALIEGMIIAGYAMGAKAGYNYIHGEIFEGYQRFETALAQARAAGFLGKNILGS
DFEFELFAHHGYGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTETFSSVPFIIRDGGQAFADKGIPN
AGGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGGMRGGKKLKAVIPGGSSAPVLPADIMMQTNMDYDSISKAGSMLGS
GAIIVMDEDVCMVKALERLSYFYYDESCGQCTPCREGTGWLYRIVHRIVEGKGCMEDLDLLDSIGNQMAGRTICALADAA
VFPVRSFTKHFRDEFVYYIEHGGPMKEHKWGGW

Sequences:

>Translated_433_residues
MAIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENISQTDVIDEVKTSGLRGRGGAGFPTGLKWSFMPRSFPG
EKYVVCNTDEGEPGTFKDRDIIMFNPHALIEGMIIAGYAMGAKAGYNYIHGEIFEGYQRFETALAQARAAGFLGKNILGS
DFEFELFAHHGYGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTETFSSVPFIIRDGGQAFADKGIPN
AGGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGGMRGGKKLKAVIPGGSSAPVLPADIMMQTNMDYDSISKAGSMLGS
GAIIVMDEDVCMVKALERLSYFYYDESCGQCTPCREGTGWLYRIVHRIVEGKGCMEDLDLLDSIGNQMAGRTICALADAA
VFPVRSFTKHFRDEFVYYIEHGGPMKEHKWGGW
>Mature_432_residues
AIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENISQTDVIDEVKTSGLRGRGGAGFPTGLKWSFMPRSFPGE
KYVVCNTDEGEPGTFKDRDIIMFNPHALIEGMIIAGYAMGAKAGYNYIHGEIFEGYQRFETALAQARAAGFLGKNILGSD
FEFELFAHHGYGAYICGEETALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTETFSSVPFIIRDGGQAFADKGIPNA
GGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGGMRGGKKLKAVIPGGSSAPVLPADIMMQTNMDYDSISKAGSMLGSG
AIIVMDEDVCMVKALERLSYFYYDESCGQCTPCREGTGWLYRIVHRIVEGKGCMEDLDLLDSIGNQMAGRTICALADAAV
FPVRSFTKHFRDEFVYYIEHGGPMKEHKWGGW

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=398, Percent_Identity=49.4974874371859, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI260656005, Length=398, Percent_Identity=49.4974874371859, Blast_Score=385, Evalue=1e-107,
Organism=Escherichia coli, GI1788620, Length=396, Percent_Identity=45.4545454545455, Blast_Score=350, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17531727, Length=399, Percent_Identity=49.1228070175439, Blast_Score=391, Evalue=1e-109,
Organism=Drosophila melanogaster, GI19920794, Length=398, Percent_Identity=50, Blast_Score=398, Evalue=1e-111,
Organism=Drosophila melanogaster, GI45550452, Length=395, Percent_Identity=48.8607594936709, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24653819, Length=407, Percent_Identity=37.5921375921376, Blast_Score=265, Evalue=7e-71,
Organism=Drosophila melanogaster, GI24653817, Length=358, Percent_Identity=37.1508379888268, Blast_Score=233, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR011537
- InterPro:   IPR011538
- InterPro:   IPR019554 [H]

Pfam domain/function: PF01512 Complex1_51K; PF10589 NADH_4Fe-4S; PF10531 SLBB [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47386; Mature: 47254

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENISQTDVIDEVKTSGLRGR
CCEECCCCEEECCCCCCCCCEEHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GGAGFPTGLKWSFMPRSFPGEKYVVCNTDEGEPGTFKDRDIIMFNPHALIEGMIIAGYAM
CCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
GAKAGYNYIHGEIFEGYQRFETALAQARAAGFLGKNILGSDFEFELFAHHGYGAYICGEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEECCH
TALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTETFSSVPFIIRDGGQAFADKGIPN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCC
AGGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGGMRGGKKLKAVIPGGSSAPVLPADI
CCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHH
MMQTNMDYDSISKAGSMLGSGAIIVMDEDVCMVKALERLSYFYYDESCGQCTPCREGTGW
EEECCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCCCCCHH
LYRIVHRIVEGKGCMEDLDLLDSIGNQMAGRTICALADAAVFPVRSFTKHFRDEFVYYIE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
HGGPMKEHKWGGW
CCCCCCCCCCCCC
>Mature Secondary Structure 
AIYQSGVIFDQVDTANPDCWTLDEYVKRGGYTALRKILSENISQTDVIDEVKTSGLRGR
CEECCCCEEECCCCCCCCCEEHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
GGAGFPTGLKWSFMPRSFPGEKYVVCNTDEGEPGTFKDRDIIMFNPHALIEGMIIAGYAM
CCCCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHH
GAKAGYNYIHGEIFEGYQRFETALAQARAAGFLGKNILGSDFEFELFAHHGYGAYICGEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEECCH
TALLESLEGKKGQPRFKPPFPASFGLYGKPTTINNTETFSSVPFIIRDGGQAFADKGIPN
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCC
AGGTKLFCISGHVERPGNYEVPLGTPFAEVLKMAGGMRGGKKLKAVIPGGSSAPVLPADI
CCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCHHH
MMQTNMDYDSISKAGSMLGSGAIIVMDEDVCMVKALERLSYFYYDESCGQCTPCREGTGW
EEECCCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHEEECCCCCCCCCCCCCCHH
LYRIVHRIVEGKGCMEDLDLLDSIGNQMAGRTICALADAAVFPVRSFTKHFRDEFVYYIE
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
HGGPMKEHKWGGW
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]