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The map label for this gene is grxB [H]

Identifier: 161870581

GI number: 161870581

Start: 1680320

End: 1681015

Strand: Reverse

Name: grxB [H]

Synonym: NMCC_1647

Alternate gene names: 161870581

Gene position: 1681015-1680320 (Counterclockwise)

Preceding gene: 161870584

Following gene: 161870580

Centisome position: 78.06

GC content: 52.16

Gene sequence:

>696_bases
GTGGCGCGGGGTGTTAAGGTAGCCGGTACCGACAGGTTGACGAGGAATATTTTGATGAAACTGTATATTTACGACCATTG
CCCGTTTTGCGTGCGTGCGCGGATGGCTGCCGGGCTGTTTGGCGCGGACGTTGAAGAAGCCGTGCTGGCAAACGACGACG
AGGCAACGCCGATCGGTATGATCGGTGCGAAACAAGTGCCCGTCCTGCAAAAAGAAGACGGTTCGTTTATGGGCGAGAGT
TTGGACATTGTGCGGCATTTCGACCGCGAAGACCGTCTGAAAGACGAAGTCCGCCCCGAGATACGGGCGTGGCTGGACAA
GGTGGGCGGATACAACGACAAACTGGTGCAGCCGCGCGTGATCAAAATCGGGCTGCCTGAATTTGCAACGCCGGAAGCGG
TGAAATATTTTACAGACAAAAAAGAGAAAAGCATCGGCAGCTTTTCCGCCAATTTGAATAAAACCGCCCAATACCTCGAA
CGGATAAACGCAGATTTGCAAGAGTTGGAAAATTTGATGGACGGTGCTTCAGACGGCATCAACGGCGGAATCGGTATGGA
GGATATTTTGGTTTTCCCCGTTTTGAGGAATCTGACCGTGGTGCGCGGCATCGAATGGCCCCAAAAGGTGATGGGTTATT
TGATGACGATGAGTGAAAAATCGGGCGTGCCGCTTTATTTTGACAGGGCATTGTAA

Upstream 100 bases:

>100_bases
GGCGCATTTTTATGCGTCAAATTTCGTTAACAGACTATTTTTGCAAAGGTCTCAGCTTATTTATTTACGGTGCATAGGCG
GGAAGATAAACTTGTTTCGG

Downstream 100 bases:

>100_bases
AAGTGGCTGTTATTAACTGACAGATGAAGGAGGTTCTACCCTATTTGAGGTAAACTCTATTTACCATTGGCCGAAATACC
AGTGCTTATCTCCAAGACGA

Product: glutaredoxin 2

Products: NA

Alternate protein names: Grx2 [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MARGVKVAGTDRLTRNILMKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGMIGAKQVPVLQKEDGSFMGES
LDIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRVIKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLE
RINADLQELENLMDGASDGINGGIGMEDILVFPVLRNLTVVRGIEWPQKVMGYLMTMSEKSGVPLYFDRAL

Sequences:

>Translated_231_residues
MARGVKVAGTDRLTRNILMKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGMIGAKQVPVLQKEDGSFMGES
LDIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRVIKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLE
RINADLQELENLMDGASDGINGGIGMEDILVFPVLRNLTVVRGIEWPQKVMGYLMTMSEKSGVPLYFDRAL
>Mature_230_residues
ARGVKVAGTDRLTRNILMKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGMIGAKQVPVLQKEDGSFMGESL
DIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRVIKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLER
INADLQELENLMDGASDGINGGIGMEDILVFPVLRNLTVVRGIEWPQKVMGYLMTMSEKSGVPLYFDRAL

Specific function: Involved in reducing some disulfides in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase [H]

COG id: COG2999

COG function: function code O; Glutaredoxin 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787303, Length=216, Percent_Identity=45.8333333333333, Blast_Score=191, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR007494
- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR011901
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF04399 Glutaredoxin2_C [H]

EC number: NA

Molecular weight: Translated: 25832; Mature: 25701

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARGVKVAGTDRLTRNILMKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGM
CCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEC
IGAKQVPVLQKEDGSFMGESLDIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRV
CCCCCCCCEECCCCCCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCEE
IKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLERINADLQELENLMDGASDGI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCC
NGGIGMEDILVFPVLRNLTVVRGIEWPQKVMGYLMTMSEKSGVPLYFDRAL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCC
>Mature Secondary Structure 
ARGVKVAGTDRLTRNILMKLYIYDHCPFCVRARMAAGLFGADVEEAVLANDDEATPIGM
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCEEC
IGAKQVPVLQKEDGSFMGESLDIVRHFDREDRLKDEVRPEIRAWLDKVGGYNDKLVQPRV
CCCCCCCCEECCCCCCCHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCEE
IKIGLPEFATPEAVKYFTDKKEKSIGSFSANLNKTAQYLERINADLQELENLMDGASDGI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHCCCCCCC
NGGIGMEDILVFPVLRNLTVVRGIEWPQKVMGYLMTMSEKSGVPLYFDRAL
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]