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The map label for this gene is ndk [H]

Identifier: 161870180

GI number: 161870180

Start: 1213706

End: 1214017

Strand: Direct

Name: ndk [H]

Synonym: NMCC_1220

Alternate gene names: 161870180

Gene position: 1213706-1214017 (Clockwise)

Preceding gene: 161870179

Following gene: 161870181

Centisome position: 56.36

GC content: 50.96

Gene sequence:

>312_bases
ATGAAGCAGCTTACTCTCAAAGAGGCGCAAGAATTTTATGCGGTTCATAAAGACCGCCCCTTCTACGCCGGATTGGTTGA
ATTTATGACCGGCGGTCCGGTTATGATTCAGGTATTAGAGGGTGAAAACGCCGTCCTGAAAAACCGCGAACTGATGGGTG
CAACTAATCCTTCCGAAGCCGCCGAAGGCACGATACGCGCGGACTTTGCCACTTCGGTCAGCATTAATGCCGTACACGGT
TCCGACAGCGTGGAAAATGCCGCTTTGGAAATTGCCTACTTTTTCAGCCAAACCGAAATCTGCCCCCGTTGA

Upstream 100 bases:

>100_bases
TACCATCTCCATCATCAAACCCGATGCCGTCGGCAAAAATGTTATCGGCAAAATATACAGCCGCTTTGAGGAGAACGGTC
TGAAAATCGTTGCCGCCAAA

Downstream 100 bases:

>100_bases
TACAATACACCGCCCAACTCCTCTTCAGACGGCATAAATATATCCATGCCGTCTGAAAACTCTGTTGCAAAAGGCTTCAA
ATCAAACTTGCCTGCCCTGC

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MKQLTLKEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPSEAAEGTIRADFATSVSINAVHG
SDSVENAALEIAYFFSQTEICPR

Sequences:

>Translated_103_residues
MKQLTLKEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPSEAAEGTIRADFATSVSINAVHG
SDSVENAALEIAYFFSQTEICPR
>Mature_103_residues
MKQLTLKEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPSEAAEGTIRADFATSVSINAVHG
SDSVENAALEIAYFFSQTEICPR

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=91, Percent_Identity=49.4505494505495, Blast_Score=97, Evalue=4e-21,
Organism=Homo sapiens, GI4557797, Length=91, Percent_Identity=49.4505494505495, Blast_Score=96, Evalue=4e-21,
Organism=Homo sapiens, GI38045913, Length=91, Percent_Identity=49.4505494505495, Blast_Score=96, Evalue=4e-21,
Organism=Homo sapiens, GI66392203, Length=91, Percent_Identity=46.1538461538462, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI66392227, Length=91, Percent_Identity=46.1538461538462, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI66392205, Length=91, Percent_Identity=46.1538461538462, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI4505409, Length=91, Percent_Identity=46.1538461538462, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI66392192, Length=91, Percent_Identity=46.1538461538462, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI4826862, Length=103, Percent_Identity=42.7184466019417, Blast_Score=90, Evalue=4e-19,
Organism=Homo sapiens, GI5031951, Length=100, Percent_Identity=41, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI37574614, Length=104, Percent_Identity=36.5384615384615, Blast_Score=70, Evalue=4e-13,
Organism=Homo sapiens, GI7019465, Length=104, Percent_Identity=36.5384615384615, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788866, Length=103, Percent_Identity=60.1941747572816, Blast_Score=140, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17506807, Length=102, Percent_Identity=44.1176470588235, Blast_Score=95, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6322783, Length=95, Percent_Identity=42.1052631578947, Blast_Score=90, Evalue=6e-20,
Organism=Drosophila melanogaster, GI45549037, Length=92, Percent_Identity=46.7391304347826, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 11271; Mature: 11271

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLTLKEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPSEA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCEECCCEECCCCCCCCC
AEGTIRADFATSVSINAVHGSDSVENAALEIAYFFSQTEICPR
CCCEEEECEECEEEEEEEECCCCCCHHHEEEEEEECCCCCCCC
>Mature Secondary Structure
MKQLTLKEAQEFYAVHKDRPFYAGLVEFMTGGPVMIQVLEGENAVLKNRELMGATNPSEA
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCCCEECCCEECCCCCCCCC
AEGTIRADFATSVSINAVHGSDSVENAALEIAYFFSQTEICPR
CCCEEEECEECEEEEEEEECCCCCCHHHEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA